Mlembi: Morris Wright
Tsiku La Chilengedwe: 26 Epulo 2021
Sinthani Tsiku: 12 Epulo 2025
Anonim
Paramyloidosis: ndi chiyani ndipo zizindikiro zake ndi ziti - Thanzi
Paramyloidosis: ndi chiyani ndipo zizindikiro zake ndi ziti - Thanzi

Zamkati

Paramyloidosis, yotchedwanso matenda am'mapazi kapena Familial Amyloidotic Polyneuropathy, ndi matenda osowa omwe alibe mankhwala, obadwa nawo, omwe amadziwika ndikupanga ulusi wama amyloid ndi chiwindi, womwe umayika m'matumbo ndi misempha, kuwawononga pang'onopang'ono.

Matendawa amatchedwa matenda a kumapazi chifukwa ndi m'mapazi pomwe zizindikiro zimawonekera koyamba ndipo, pang'ono ndi pang'ono, zimawonekera m'malo ena amthupi.

Mu paramyloidosis, kuwonongeka kwa mitsempha yotumphukira kumapangitsa kuti madera osakhudzidwa ndi mitsempha iyi akhudzidwe, zomwe zimabweretsa kusintha pakumva kutentha, kuzizira, kupweteka, kukhudzidwa ndi kugwedera. Kuphatikiza apo, mphamvu yamagalimoto imakhudzidwanso ndipo minofu imataya minofu yawo, kuvutika kwambiri ndi kuchepa mphamvu, zomwe zimabweretsa zovuta kuyenda ndikugwiritsa ntchito ziwalozo.

Zizindikiro zake ndi ziti

Paramyloidosis imakhudza zotumphukira zamanjenje, zomwe zimapangitsa kuti:


  • Mavuto amtima, monga kuthamanga kwa magazi, arrhythmias ndi ma atrioventricular;
  • Kulephera kwa Erectile;
  • Mavuto am'mimba, monga kudzimbidwa, kutsegula m'mimba, kusachita bwino m'mimbamo ndi nseru ndi kusanza, chifukwa chovuta kutulutsa m'mimba;
  • Zovuta zamikodzo, monga kusungira mkodzo ndi kusadziletsa komanso kusintha kwa kusefera kwaminyewa;
  • Matenda amaso, monga kuwonongeka kwa ophunzira komanso khungu lotsatira.

Kuphatikiza apo, pakadwala matendawa, munthuyo amatha kudwala chifukwa chochepetsedwa, kufuna njinga ya olumala kapena kugona.

Matendawa nthawi zambiri amakhala azaka zapakati pa 20 ndi 40, zomwe zimayambitsa kufa kwa zaka 10 mpaka 15 kuyambira pomwe zizindikiro zoyambirira zidayamba.

Zomwe zingayambitse

Paramyloidosis ndi matenda obadwa nawo otetezedwa ndi autosomal omwe alibe mankhwala ndipo amayamba chifukwa cha kusintha kwa majini mu protein ya TTR, yomwe imakhala ndikutulutsa m'minyewa ndi mitsempha ya chinthu cha fibrillar chotulutsa chiwindi, chotchedwa amyloid.


Kuyika kwa chinthuchi m'matumba kumabweretsa kuchepa kwachangu pakukhudzidwa ndi chidwi ndi kuyendetsa galimoto.

Momwe mankhwalawa amachitikira

Chithandizo chothandiza kwambiri cha paramyloidosis ndikuthira chiwindi, komwe kumatha kuchepetsa kukula kwa matendawa pang'ono. Kugwiritsa ntchito mankhwala osokoneza bongo kumawonetsa kuti thupi la munthu limakana chiwalo chatsopanocho, koma zotsatira zoyipa zimatha.

Kuphatikiza apo, adotolo amathanso kulangiza mankhwala, otchedwa Tafamidis, omwe amathandiza kuchepetsa kupita patsogolo kwa matendawa.

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