Apolipoprotein CII

Apolipoprotein CII (apoCII) ndi puloteni yomwe imapezeka m'magulu akuluakulu amafuta omwe m'mimba mwake mumayamwa. Amapezekanso mu lipoprotein yotsika kwambiri (VLDL), yomwe imapangidwa ndi triglycerides (mtundu wamafuta m'magazi anu).

Nkhaniyi ikufotokoza za mayeso omwe amagwiritsidwa ntchito kuwunika apoCII mchitsanzo cha magazi anu.

Muyenera kuyesa magazi.

Mutha kuuzidwa kuti musadye kapena kumwa chilichonse kwa maola 4 kapena 6 mayeso asanayesedwe.

Singano ikalowetsedwa kuti mutenge magazi, mutha kumva kupweteka, kapena kungobaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka komwe singano idalowetsedwa.

Kuyeza kwa ApoCII kumatha kuthandizira kudziwa mtundu kapena chifukwa chamafuta am'magazi ambiri. Sizikudziwika ngati zotsatira zoyeserera zimathandizira chithandizo. Chifukwa cha izi, makampani ambiri a inshuwaransi yazaumoyo sangalipire mayeso. Ngati mulibe cholesterol chambiri kapena matenda amtima kapena mbiri yamabanja pazomwezi, mayesowa sangakulimbikitseni.

Mtundu wabwinobwino ndi 3 mpaka 5 mg / dL. Komabe, zotsatira za apoCII nthawi zambiri zimanenedwa kuti zilipo kapena palibe.

Zitsanzo pamwambapa ndizoyesa wamba pazotsatira za mayesowa. Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi dokotala wanu tanthauzo la zotsatira zanu zoyesa.

Kuchuluka kwa apoCII kumatha kukhala chifukwa cha mbiri ya banja yakusowa kwa lipoprotein lipase. Izi ndizomwe thupi silimaphwanya mafuta mwachizolowezi.

Magawo a ApoCII amawonekeranso mwa anthu omwe ali ndi vuto losowa lotchedwa mabanja apoprotein CII. Izi zimayambitsa matenda a chylomicronemia, vuto lina lomwe thupi silimaphwanya mafuta mwachizolowezi.

Zowopsa zomwe zimakhudza kukoka magazi ndizochepa koma zingaphatikizepo:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Hematoma (magazi akuchuluka pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Kuyeza kwa apolipoprotein kungapereke tsatanetsatane wokhudzana ndi chiwopsezo cha matenda amtima, koma phindu lowonjezera la mayesowa kupitirira gulu la lipid silikudziwika.

ApoCII; Apopuloteni CII; ApoC2; Lipoprotein lipase kusowa - apolipoprotein CII; Chylomicronemia syndrome - apolipoprotein CII

• Kuyezetsa magazi

Chen X, Zhou L, Hussain MM. Lipids ndi dyslipoproteinemia. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 17.

Genest J, Libby P. Lipoprotein zovuta ndi matenda amtima. Mu: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2019: chap 48.

Remaley AT, Mtsinje wa TD, Warnick GR. Lipids, lipoproteins, apolipoproteins, ndi zina zowopsa pamtima. Mu: Rifai N, mkonzi. Tietz Textbook of Clinical Chemistry ndi Molecular Diagnostics. Lachisanu ndi chimodzi. St Louis, MO: Elsevier; 2018: mutu 34.

Robinson JG. Matenda amadzimadzi amadzimadzi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 195.