Antigen ya HLA-B27
HLA-B27 ndiyeso la magazi kuti mupeze mapuloteni omwe amapezeka pamwamba pamaselo oyera amwazi. Puloteni amatchedwa leukocyte antigen ya anthu B27 (HLA-B27).
Ma antigen a leukocyte (HLAs) ndi mapuloteni omwe amathandiza chitetezo cha mthupi kudziwa kusiyana pakati pa maselo ake ndi zinthu zakunja, zovulaza. Amapangidwa kuchokera kumalangizo ndi majini obadwa nawo.
Muyenera kuyesa magazi. Nthawi zambiri, magazi amatengedwa pamitsempha yomwe ili mkati mwa chigongono kapena kumbuyo kwa dzanja.
Nthawi zambiri, palibe njira zapadera zofunika kukonzekera mayeso.
Singano ikalowetsedwa kuti mutenge magazi, mutha kumva kupweteka pang'ono, kapena kungomva kapena kubaya. Pambuyo pake, pakhoza kukhala kupindika.
Wothandizira zaumoyo wanu akhoza kuyitanitsa mayesowa kuti athandize kudziwa chomwe chimayambitsa kupweteka limodzi, kuuma, kapena kutupa. Mayesowa atha kuchitidwa limodzi ndi mayeso ena, kuphatikiza:
- Mapuloteni othandizira C
- Mlingo wa sedimentation wa erythrocyte (ESR)
- Chifuwa cha nyamakazi
- X-ray
Kuyesedwa kwa HLA kumagwiritsidwanso ntchito kufananitsa minofu yoperekedwa ndi mnofu wa munthu yemwe akumupangira chiwalo. Mwachitsanzo, zitha kuchitika ngati munthu akufuna kumuika impso kapena kumuika m'mafupa.
Zotsatira zabwinobwino (zoipa) zikutanthauza kuti HLA-B27 kulibe.
Kuyesedwa koyenera kumatanthauza kuti HLA-B27 ilipo. Ikuwonetsa chiopsezo chachikulu kuposa chiwopsezo chokhala ndi zovuta zina zama auto. Matenda osokoneza bongo ndi omwe amapezeka pomwe chitetezo chamthupi chimagwirira molakwika ndikuwononga minofu yabwinobwino ya thupi.
Zotsatira zabwino zitha kuthandizira omwe akukuthandizani kuti adziwe mtundu wina wamatenda am'mimba wotchedwa spondyloarthritis. Matenda amtunduwu amaphatikizapo zovuta izi:
- Ankylosing spondylitis
- Matenda a nyamakazi okhudzana ndi matenda a Crohn kapena ulcerative colitis
- Matenda a Psoriatic (nyamakazi yokhudzana ndi psoriasis)
- Matenda a nyamakazi
- Sacroiliitis (kutupa kwa mgwirizano wa sacroiliac)
- Uveitis
Ngati muli ndi zizindikilo za spondyloarthritis, mayeso abwino a HLA-B27 angathandize kutsimikizira kuti ali ndi matendawa. Komabe, HLA-B27 imapezeka mwa anthu wamba ndipo sizitanthauza kuti muli ndi matenda nthawi zonse.
Zowopsa zokoka magazi ndizochepa, koma zingaphatikizepo:
- Kutaya magazi kwambiri
- Kukomoka kapena kumva mopepuka
- Hematoma (magazi akuchuluka pansi pa khungu)
- Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)
Mankhwala a leukocyte antigen B27; Ankylosing spondylitis-HLA; Matenda a Psoriatic-HLA; Matenda a nyamakazi-HLA
- Kuyezetsa magazi
Chernecky CC, Berger BJ. Human Leukocyte Antigen (HLA) B-27 - magazi. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 654-655.
Fagoaga KAPENA. Antigen ya leukocyte antigen: vuto lalikulu kwambiri lofananira kwamunthu. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 49.
Inman RD. Mitundu ya spondyloarthropathies. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 265.
McPherson RA, Massey HD. Chidule cha chitetezo cha mthupi komanso matenda amthupi. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 43.
Fotokozerani JD. Spondyloarthritis. Mu: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, AJ ochepa, Weyand CM, eds. Clinical Immunology: Mfundo ndi Zochita. 5th ed. Philadelphia, PA: Elsevier; 2019: mutu 57.