Kuwerengera kwa RBC

Kuwerengera kwa RBC ndi kuyezetsa magazi komwe kumayeza kuchuluka kwamagazi ofiira (RBCs) omwe muli nawo.

Ma RBC ali ndi hemoglobin, yomwe imanyamula mpweya. Kuchuluka kwa mpweya wamatupi amthupi mwanu kumadalira kuchuluka kwa ma RBC omwe muli nawo komanso momwe amagwirira ntchito.

Muyenera kuyesa magazi.

Palibe kukonzekera kwapadera kofunikira.

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Kuwerengera kwa RBC nthawi zambiri kumakhala gawo la kuyesa kwathunthu kwa magazi (CBC).

Kuyesaku kungathandize kuzindikira mitundu yosiyanasiyana ya kuchepa kwa magazi m'thupi (ma RBC ochepa) ndi zina zomwe zimakhudza maselo ofiira.

Zina zomwe zingafune kuwerengera RBC ndi:

• Matenda omwe amawononga mitsempha ya impso (Alport syndrome)
• Khansa yoyera yamagazi (Waldenström macroglobulinemia)
• Kusokonezeka komwe maselo ofiira amafa msanga kuposa nthawi zonse (paroxysmal nocturnal hemoglobinuria)
• Matenda a mafupa omwe mafupa ake amalowetsedwa ndi zilonda zam'mimba (myelofibrosis)

Mitundu yabwinobwino ya RBC ndi iyi:

• Amuna: maselo 4.7 mpaka 6.1 miliyoni pa microliter (maselo / mcL)
• Mkazi: masentimita 4.2 mpaka 5.4 miliyoni / mcL

Magawo omwe ali pamwambapa ndi miyeso yodziwika pazotsatira za mayesowa. Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amayesa mitundu yosiyanasiyana. Lankhulani ndi wothandizira zaumoyo wanu za tanthauzo la zotsatira zanu zoyeserera.

Ziwerengero zoposa ma RBC zitha kukhala chifukwa cha:

• Kusuta ndudu
• Vuto ndi kapangidwe ka mtima ndi magwiridwe antchito omwe amapezeka pakubadwa (matenda obadwa nawo amtima)
• Kulephera kwa mbali yakumanja ya mtima (cor pulmonale)
• Kutaya madzi m'thupi (mwachitsanzo, kutsekula m'mimba)
• Chotupa cha impso (aimpso cell carcinoma)
• Mulingo wama oxygen ochepa (hypoxia)
• Kutupa kapena kukhuthala kwamapapu (pulmonary fibrosis)
• Matenda a mafupa omwe amachititsa kuwonjezeka kwachilendo mu RBCs (polycythemia vera)

Kuwerengera kwanu kwa RBC kudzawonjezeka kwa milungu ingapo mukakhala pamwambamwamba.

Mankhwala omwe angakulitse kuchuluka kwa RBC ndi awa:

• Anabolic steroids
• Mpweya wambiri
• Gentamicin

Manambala ochepera kuposa abwinobwino a RBCs atha kukhala chifukwa cha:

• Kuchepa kwa magazi m'thupi
• Magazi
• Kulephera kwa mafupa (mwachitsanzo, poizoniyu, poizoni, kapena chotupa)
• Kuperewera kwa mahomoni otchedwa erythropoietin (oyambitsidwa ndi matenda a impso)
• Kuwonongeka kwa RBC (hemolysis) chifukwa chothiridwa magazi, kuvulala kwa chotengera magazi, kapena chifukwa china
• Khansa ya m'magazi
• Kusowa zakudya m'thupi
• Khansa ya m'mafupa yotchedwa multiple myeloma
• Chitsulo chochepa kwambiri, mkuwa, folic acid, vitamini B6, kapena vitamini B12 mu zakudya
• Madzi ochuluka mthupi (kuthirira madzi)
• Mimba

Mankhwala omwe angachepetse kuchuluka kwa RBC ndi awa:

• Mankhwala a chemotherapy
• Chloramphenicol ndi maantibayotiki ena
• Ma Hydantoins
• Methyldopa
• Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)
• Quinidine

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kutenga magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakoka magazi ndi zochepa, koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Kuchuluka kwa erythrocyte; Maselo ofiira ofiira; Kuchepa kwa magazi m'thupi - RBC count

• Kuyezetsa magazi
• Zinthu zopangidwa zamagazi
• Kuthamanga kwa magazi

Chernecky CC, Berger BJ. Maselo ofiira ofiira (RBC) - magazi. Mu: Chernecky CC, Berger BJ, olemba., Eds. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2013: 961-962.

Gallagher PG. Hemolytic anemias: maselo ofiira am'magazi komanso zopindika zamagetsi. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 152.

Little M. Kuchepetsa magazi m'thupi. Mu: Cameron P, Little M, Mitra B, Deasy C, olemba., Eds. Buku Lophunzitsira la Mankhwala Achikulire Achikulire. 5th ed. Philadelphia, PA: Elsevier; 2020: mutu 13.

Zikutanthauza RT. Yandikirani ku anemias. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 149.