Lomitapide

Zamkati

• Musanatenge lomitapide,
• Lomitapide imatha kubweretsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi kapena zomwe zalembedwa mgawo la CHENJEZO LOFUNIKA, siyani kumwa lomitapide ndikuyimbira dokotala nthawi yomweyo kapena kupeza chithandizo chadzidzidzi:

Lomitapide imatha kuwononga chiwindi. Uzani dokotala wanu ngati mwakhalapo ndi matenda a chiwindi kapena ngati munakhalapo ndi vuto la chiwindi mukamamwa mankhwala ena.Dokotala wanu akhoza kukuwuzani kuti musatenge lomitapide. Uzani dokotala wanu ngati mumamwa mowa. Kumwa mowa kungapangitse kuti mukhale ndi vuto la chiwindi. Musamwe zakumwa zoledzeretsa zoposa kamodzi patsiku mukamamwa lomitapide. Uzani dokotala ndi wamankhwala ngati mukumwa acetaminophen (Tylenol, ena), amiodarone (Cordarone), doxycycline (Doryx, Vibramycin, ena), isotretinoin (Accutane), methotrexate (Rheumatrex), minocycline (Dynacin, Minocin), tamoxif) ), kapena tetracycline (Sumycin). Ngati mukukumana ndi zizindikiro izi nthawi iliyonse mukamamwa mankhwala, siyani kumwa lomitapide ndikuyimbira dokotala nthawi yomweyo: kutopa kwambiri, kusowa mphamvu, kufooka, kunyansidwa kapena kusanza komwe kumakulirakulira kapena sikutha, kupweteka kumtunda kwakumanja gawo la m'mimba, kusowa kwa njala, khungu lachikaso kapena maso, malungo, kapena zizindikilo zonga chimfine. Dokotala wanu angafunike kusintha mlingo kapena kuimitsa kapena kuchedwetsa chithandizo chanu mukakumana ndi vuto la chiwindi.

Pulogalamu yotchedwa Juxtapid REMS^® wavomerezedwa ndi Food and Drug Administration (FDA) chifukwa chotheka kuwonongeka kwa chiwindi komwe kumakhudzana ndi kugwiritsa ntchito lomitapide. Anthu onse omwe amapatsidwa lomitapide ayenera kukhala ndi mankhwala a lomitapide ochokera kwa dokotala yemwe adalembetsa ku Juxtapid REMS^®, ndipo mudzaze mankhwalawa ku pharmacy yomwe imalembetsedwa ndi Juxtapid REMS^® kuti mulandire mankhwalawa.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira lomitapide.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba mankhwala ndi lomitapide ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lomitapide imagwiritsidwa ntchito limodzi ndi kusintha kwa zakudya (kuletsa mafuta m'thupi ndi kudya mafuta) ndi mankhwala ena kuti muchepetse kuchuluka kwa mafuta otsika kwambiri a lipoprotein (LDL) cholesterol ('cholesterol yoyipa'), cholesterol yonse, ndi mafuta ena m'magazi mwa anthu omwe ali ndi homozygous family hypercholesterolemia (HoFH; mkhalidwe wobadwa nawo momwe cholesterol sichingachotsedwe m'thupi nthawi zonse). Lomitapide sayenera kugwiritsidwa ntchito kuchepetsa mafuta m'thupi mwa anthu omwe alibe HoFH. Lomitapide ali mgulu la mankhwala otchedwa mankhwala ochepetsa mafuta m'thupi. Zimagwira pochepetsa kuchepa kwa cholesterol m'thupi kuti muchepetse kuchuluka kwa mafuta m'thupi omwe angakule pamakoma a mitsempha ndikuletsa magazi kupita kumtima, ubongo, ndi ziwalo zina za thupi.

Kuwonjezeka kwa cholesterol ndi mafuta m'mbali mwa mitsempha yanu (njira yotchedwa atherosclerosis) imachepetsa kutuluka kwa magazi, chifukwa chake, mpweya umapatsa mtima wanu, ubongo, ndi ziwalo zina za thupi lanu. Kutsitsa magazi anu wama cholesterol ndi mafuta kumatha kuthandizira kupewa matenda amtima, angina (kupweteka pachifuwa), stroko, komanso matenda amtima.

Lomitapide imabwera ngati kapisozi kotenga pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku. Lomitapide imayenera kumwa popanda chakudya m'mimba yopanda kanthu, osachepera maola awiri mutadya chakudya chamadzulo. Imwani kapu yamadzi yonse ndi mlingo uliwonse wa lomitapide.

Tengani lomitapide mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani lomitapide ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse; osagawanika, kutafuna, kusungunula, kapena kuwaphwanya.

Muyenera kumwa mankhwala othandizira mavitamini mukamamwa mankhwala a lomitapide Onetsetsani kuti mukutsatira malangizo omwe dokotala wanu wapereka mosamala.

Pitirizani kutenga lomitapide ngakhale mukumva bwino. Osasiya kumwa lomitapide osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge lomitapide,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la lomitapide, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a lomitapide. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• uzani dokotala wanu ngati mukumwa mankhwala oletsa mafungal monga fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), ndi voriconazole (Vfend); boceprevir (Wopambana); Aprepitant (Emend); ciprofloxacin (Cipro); clarithromycin (Biaxin); crizotinib (Xalkori); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (EES, E-Mycin, Erythrocin); HIV protease inhibitors monga amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (ku Kaletra), nelfinavir (Viracept), saquinavir (Invirase), ritirase) ku Kaletra), ritonavir ndi tipranavir (Aptivus), ndi teleprevir (Incivek); imatinib (Gleevec); nefazodone; telithromycin (Ketek); ndi verapamil (Calan, Covera, Isoptin, Verelan). Dokotala wanu angakuuzeni kuti musamamwe lomitapide ngati mukumwa mankhwala amodzi kapena angapo.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe adatchulidwa mgulu la CHENJEZO CHENJEZO ndi izi: aliskiren (Tekturna); alprazolam (Xanax); ambrisentan (Letairis); amiodarone (Cordarone, Pacerone); amlodipine (Norvasc, ku Caduet); bicalutamide (Casodex); cilostazol (Pletal); mankhwala ena apakamwa a shuga monga saxagliptin (Onglyza ku Kombiglyze) ndi sitagliptin (Januvia, ku Janumet); cimetidine (Tagament); colchicine (Colcrys); dabigatran (Pradaxa); digoxin (Lanoxin); everolimus (Wothandizira, Zortress); fexofenadine (Allegra); fluoxetine (Prozac); fluvoxamine (Luvox); isoniazid (INH, Nydrazid); lapatinib (Tykerb); nthawi (Selzentry); mankhwala omwe amaletsa chitetezo cha mthupi monga cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) ndi tacrolimus (Prograf); nilotinib (Tasigna); njira zakulera zam'kamwa (mapiritsi olera); mankhwala ena ochepetsa mafuta m'thupi monga atorvastatin (Lipitor, ku Caduet, ku Liptruzet), lovastatin (Mevacor), ndi simvastatin (Zocor, ku Simcor, ku Vytorin); pazopanib (Wotchuka); ranitidine (Zantac); ranolazine (Ranexa); maphunziro (Brilinta); tolvaptan (Samsca); topotecan (Hycamtin); warfarin (Coumadin); ndi zileuton (Zyflo). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi lomitapide, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu za mankhwala omwe mumamwa, makamaka ginkgo kapena goldenseal.
• ngati mukumwa cholestyramine (Questran), colesevelam (WellChol), kapena colestipol (Colestid), imwani maola 4 musanadutse kapena maola 4 lomitapide.
• Uzani dokotala wanu ngati mwakhalapo ndi galactose tsankho kapena glucose-galactose malabsorption (malo obadwa nawo omwe thupi silingalekerere lactose), mavuto am'mimba kapena m'mimba, kapamba kapena matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Ngati ndinu wamkazi yemwe angatenge mimba, muyenera kutenga mayeso asanatenge lomitapide. Ngati mutha kutenga pakati, muyenera kugwiritsa ntchito njira yolerera poyenera kulandira lomitapide. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukamamwa lomitapide, siyani kumwa mankhwalawo ndikuyimbira dokotala nthawi yomweyo. Lomitapide itha kuvulaza mwana wosabadwayo.
• uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukamamwa lomitapide.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Dokotala wanu angakuuzeni kuti mudye zakudya zopanda mafuta ambiri. Kudya zakudya zamafuta ochepa kumachepetsa mwayi woti muzikhala ndi mavuto m'mimba kuphatikiza nseru, kusanza, m'mimba, komanso kutsekula m'mimba mukamamwa lomitapide. Tsatirani malangizo onse azakudya mwadongosolo omwe adokotala anu kapena odyetserako za zakudya amapatsidwa mosamala.

Pitani muyezo womwe mwasowa ndikupitiliza dongosolo lanu lapa dosing tsiku lotsatira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Lomitapide imatha kubweretsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• nseru
• kusanza
• kupweteka m'mimba
• kudzimbidwa
• kuphulika
• mpweya
• kukhumudwa m'mimba
• kuonda
• mutu
• chizungulire
• chikhure
• mphuno
• kupweteka kwa msana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi kapena zomwe zalembedwa mgawo la CHENJEZO LOFUNIKA, siyani kumwa lomitapide ndikuyimbira dokotala nthawi yomweyo kapena kupeza chithandizo chadzidzidzi:

• kutsegula m'mimba kwambiri
• wamisala
• Kuchepetsa mkodzo kutulutsa

Lomitapide imatha kubweretsa mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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