Duvelisib

Zamkati

• Musanatenge duvelisib,
• Duvelisib ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Duvelisib ingayambitse matenda oopsa kapena owopsa. Uzani dokotala wanu ngati muli ndi matenda, kapena ngati mwakhalapo ndi cytomegalovirus (CMV; matenda opatsirana omwe angayambitse zizindikiro kwa odwala omwe ali ndi chitetezo chamthupi chofooka). Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: malungo, zilonda zapakhosi, kuzizira, kupuma movutikira, kapena zizindikilo zina za matenda.

Duvelisib itha kuyambitsa kutsekula m'mimba kapena colitis (kutupa kwamatumbo akulu). Uzani dokotala wanu ngati muli ndi matenda otsekula m'mimba kapena ngati mudakhalapo ndi matenda am'mimba kapena zina zomwe zimakhudza m'mimba kapena m'matumbo. Ngati mukumane ndi izi, itanani dokotala wanu mwachangu: kuwonjezeka kwamatumbo tsiku limodzi, magazi mu mpando wanu, kapena kukokana m'mimba kapena kupweteka kulikonse.

Duvelisib itha kuyambitsa khungu kapena kuwopsa kwa khungu. Ngati mukukumana ndi izi, pitani kuchipatala msanga: zidzolo zatsopano kapena zowonjezereka, zotupa ndi malungo, zotupa ndi kuyabwa, zotupa kapena khungu losenda, kapena zilonda zopweteka pakhungu, milomo, kapena mkamwa mwanu.

Duvelisib ingayambitse pneumonitis yowopsa kapena yowopsa (kutupa kwa mapapo). Uzani dokotala wanu ngati muli ndi matenda am'mapapo kapena kupuma. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: chifuwa chatsopano kapena chowonjezeka, kupuma movutikira, kupumira, kapena kupuma pang'ono.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti muwone momwe thupi lanu likuyankhira ku duvelisib.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba kulandira mankhwala ndi duvelisib ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Duvelisib amagwiritsidwa ntchito pochiza khansa ya m'magazi (CLL; mtundu wa khansa womwe umayambira m'maselo oyera a magazi) kapena ma lymphocytic lymphoma (SLL; mtundu wa khansa womwe umayamba makamaka m'matenda am'mimba) omwe abwerera kapena osamvera mankhwala ena osachepera awiri. Amagwiritsidwanso ntchito kuthana ndi mitundu ina ya follicular lymphoma (FL; mtundu wa khansa womwe umayambira m'maselo oyera amwazi) mwa akulu omwe khansa yomwe yabwerera kapena yosamvera mankhwala ena awiri. Duvelisib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito potseka zikwangwani zomwe zimapangitsa ma cell a khansa kuchulukana. Izi zimathandiza kuletsa kufalikira kwa maselo a khansa.

Duvelisib amabwera ngati kapisozi woti atenge pakamwa. Nthawi zambiri amatengedwa kawiri tsiku lililonse kapena wopanda chakudya. Tengani duvelisib mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani duvelisib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza lonse kapisozi; osatsegula, kutafuna, kapena kuwaswa.

Dokotala wanu akhoza kuchepetsa mlingo wanu wa duvelisib kapena kukuuzani kuti musiye kumwa mankhwalawa kwa kanthawi kapena kwamuyaya ngati mukukumana ndi zovuta zina mukamalandira. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zomwe mumakumana nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Pitirizani kutenga duvelisib ngakhale mukumva bwino. Osasiya kumwa duvelisib osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge duvelisib,

• Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la duvelisib, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a duvelisib. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mumamwa kapena mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Epitol, Tegretol, Teril, ena); clarithromycin (Biaxin); Mankhwala omwe amachiza kachilombo ka HIV monga efavirenz (Sustiva, ku Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ndi ritonavir (Norvir, mwa ena); itraconazole (Onmel, Sporanox); ketoconazole, midazolam; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rimactane, ku Rifamate). Mankhwala ena ambiri amathanso kulumikizana ndi duvelisib, chifukwa chake onetsetsani kuti mumauza dokotala za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa mimba musanayambe kumwa duvelisib. Simuyenera kutenga pakati mukamamwa mankhwala a duvelisib. Ngati ndinu wamkazi, muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamamwa mankhwala a duvelisib komanso osachepera mwezi umodzi mutatha kumwa. Ngati ndinu wamwamuna ndipo mnzanu atha kukhala ndi pakati, muyenera kugwiritsa ntchito njira yoletsa yothandiza kubereka mukamalandira chithandizo komanso kwa mwezi umodzi mutalandira mankhwala. Ngati inu kapena mnzanu mutakhala ndi pakati mukatenga duvelisib, itanani dokotala wanu mwachangu. Duvelisib atha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa duvelisib komanso kwa mwezi umodzi mutatha kumwa mankhwala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya mlingo wa duvelisib pasanathe maola 6, tengani mlingo womwe mwaphonya mukangokumbukira kenako mutenge mlingo wotsatira panthawiyo. Komabe, ngati mwaphonya mlingo wa maola opitilira 6, tulukani mulingo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Duvelisib ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kudzimbidwa
• kutopa
• mutu
• minofu kapena kujowina kupweteka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• maso achikaso kapena khungu; kupweteka m'mimba; kuvulala kapena kutuluka magazi mosadziwika; kusowa chilakolako; mkodzo wachikaso kapena wabulauni; mipando yotumbululuka; kapena kupweteka kumtunda chakumanja kwam'mimba

Duvelisib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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