Kodi Red Man Syndrome Ndi Chiyani?

Zamkati

• Zizindikiro
• Zithunzi za red man syndrome
• Zoyambitsa
• Zowopsa
• Zochitika
• Chithandizo
• Chiwonetsero

Chidule

Matenda ofiira a Red man ndiwovutikira kwambiri ku mankhwala a vancomycin (Vancocin). Nthawi zina amatchedwa red khosi matenda. Dzinali limachokera ku zotupa zofiira zomwe zimayamba pankhope, m'khosi, ndi chifuwa cha anthu omwe akhudzidwa.

Vancomycin ndi mankhwala opha tizilombo. Nthawi zambiri amagwiritsidwa ntchito pochiza matenda opatsirana kwambiri a bakiteriya, kuphatikiza omwe amayamba chifukwa cha staphylococci yolimbana ndi methicillin, yomwe imadziwika kuti MRSA. Mankhwalawa amaletsa mabakiteriya kuti asapange makoma am'magulu, zomwe zimapangitsa kuti mabakiteriya afe. Izi zimalepheretsa kukula kwina ndikuletsa kufalikira kwa matenda.

Vancomycin itha kuperekedwanso ngati munthu ali ndi chifuwa cha mitundu ina ya maantibayotiki, monga penicillin.

Zizindikiro

Chizindikiro chachikulu cha red man syndrome ndikutuluka kofiira kwambiri kumaso, m'khosi, komanso kumtunda. Nthawi zambiri zimachitika mukamalowetsedwa mtsempha (IV) wa vancomycin. Nthawi zambiri, mankhwalawa akaperekedwa mwachangu, zidzolo zimayamba kuwonekera.

Ziphuphu nthawi zambiri zimawoneka mkati mwa mphindi 10 mpaka 30 kuyambira chithandizo cha vancomycin kuyambira. Kusintha kochedwa kwawonanso kwa anthu omwe akhala akulandila vancomycin infusions kwa masiku angapo.

Nthawi zambiri, zomwe zimachitika pambuyo pa kulowetsedwa kwa vancomycin ndizofatsa kotero kuti zimatha kuzindikirika. Zovuta komanso kumva kutentha ndi kuyabwa zimawonedwanso kawirikawiri. Zizindikiro zina zochepa koma zowopsa ndizo:

• hypotension (kuthamanga kwa magazi)
• kupuma movutikira
• chizungulire
• mutu
• kuzizira
• malungo
• kupweteka pachifuwa

Zithunzi za red man syndrome

Zoyambitsa

Madokotala poyamba ankakhulupirira kuti red man syndrome imayamba chifukwa chazinyalala pokonzekera vancomycin. Munthawi imeneyi, matendawa amatchedwa "Matope a Mississippi." Komabe, matenda a red man akupitilizabe kuchitika ngakhale kusintha kwakukulu pakukonzekera kwa vancomycin.

Zadziwika tsopano kuti red man syndrome imayamba chifukwa chochulukitsa kwa ma cell amthupi ena mthupi kutengera vancomycin. Maselowa, omwe amatchedwa mast cell, amalumikizidwa ndi zomwe sizigwirizana ndi thupi lawo. Akakondweretsedwa kwambiri, maselo akuluakulu amatulutsa mankhwala ambiri otchedwa histamine. Mbiri yake imabweretsa zizindikilo za red man syndrome.

Mitundu ina ya maantibayotiki, monga ciprofloxacin (Cipro), cefepime, ndi rifampin (Rimactane, Rifadin), amathanso kuyambitsa matenda a red man nthawi zina.

[KUKOPA: Dziwani zambiri: Zotsatira zoyipa za maantibayotiki »]

Zowopsa

Choopsa chachikulu pakukula kwa matenda a red man ndikulandila vancomycin mwachangu kwambiri. Pofuna kuchepetsa chiopsezo chokhala ndi matenda ofiira, vancomycin iyenera kuperekedwa pang'onopang'ono kwa ola limodzi.

Matenda a Red man amapezeka kuti amapezeka kawirikawiri mwa anthu omwe ali ochepera zaka 40, makamaka ana.

Ngati mudakhalapo ndi red man syndrome poyankha vancomycin, ndizotheka kuti mudzayambiranso muzithandizo zamtsogolo za vancomycin. Kukula kwa chizindikiro sikuwoneka ngati kosiyana pakati pa anthu omwe adakumana ndi matenda ofiira m'mbuyomu ndi anthu omwe adakumana nawo koyamba.

Zizindikiro za red man syndrome zitha kukulirakulira mukamalandira mankhwala ena, monga:

• mitundu ina ya maantibayotiki, monga ciprofloxacin kapena rifampin
• othetsa ululu ena
• zopumulitsako minofu

Izi ndichifukwa choti mankhwalawa amatha kupititsa patsogolo ma cell amthupi omwewo monga vancomycin, zomwe zimapangitsa kuti pakhale mwayi wothana nawo.

Kutalika kwa vancomycin nthawi yayitali kumachepetsa chiopsezo choti mungakhale ndi red man syndrome. Ngati pakufunika mankhwala angapo a vancomycin, ayenera kupatsidwa infusions pafupipafupi pamlingo wotsika.

Zochitika

Pali malipoti osiyanasiyana okhudzana ndi matenda a red man. Zapezeka kuti zimapezeka kulikonse kuyambira 5 mpaka 50 peresenti ya anthu omwe amathandizidwa ndi vancomycin mchipatala. Milandu yofatsa kwambiri mwina silinganenedwe nthawi zonse, yomwe imatha kuyambitsa kusiyana kwakukulu.

Chithandizo

Kutupa komwe kumayambitsidwa ndi red man syndrome kumawonekera nthawi yayitali kapena patangopita nthawi yochepa kulowetsedwa kwa vancomycin. Zizindikiro zikayamba, matenda ofiira amuna amakhala pafupifupi mphindi 20. Nthawi zina, amatha maola angapo.

Ngati mukukumana ndi red man syndrome, dokotala wanu ayimitsa chithandizo cha vancomycin nthawi yomweyo. Akupatsani mankhwala akumwa a antihistamine kuti akuthandizeni kuthana ndi matenda anu. Pa milandu yoopsa kwambiri, monga yokhudza hypotension, mungafunike madzi amtundu wa IV, corticosteroids, kapena zonse ziwiri.

Dokotala wanu amadikirira kuti zizindikiro zanu ziziyenda bwino musanayambirenso mankhwala anu a vancomycin. Adzapereka mlingo wanu wonse pang'onopang'ono kuti muchepetse chiopsezo chanu.

Chiwonetsero

Matenda a red man amapezeka nthawi zambiri vancomycin ikalowetsedwa mwachangu kwambiri, koma imatha kuchitika ngati mankhwalawa amaperekedwanso m'njira zina. Chizindikiro chofala kwambiri ndikutuluka kofiira kwambiri komwe kumafikira kumtunda, komanso kuyabwa kapena kutentha.

Zizindikiro za red man syndrome nthawi zambiri sizowopsa, koma zimatha kukhala zosasangalatsa. Zizindikiro zimangokhala kwakanthawi ndipo zimatha kuyang'aniridwa ndi antihistamines. Ngati mwakhala mukudwala matenda ofiira m'mbuyomu, mumatha kudwala. Adziwitseni dokotala musanalandire kulowetsedwa kwa vancomycin ngati mudachitapo izi kale.