Fungo lodziwika bwino la Mediterranean

Fungo lodziwika bwino la Mediterranean (FMF) ndimatenda achilendo omwe amapitilira m'mabanja (obadwa nawo). Zimaphatikizapo kutentha thupi mobwerezabwereza komanso kutupa komwe kumakhudza nthawi yayitali pamimba, pachifuwa, kapena palumikizidwe.

FMF nthawi zambiri imayamba chifukwa cha kusintha kwa majini otchedwa MEFV. Jini imeneyi imapanga puloteni yoletsa kutupa. Matendawa amapezeka mwa anthu okhawo omwe adalandira makope awiri amtundu wosinthidwa, m'modzi kuchokera kwa kholo lililonse. Izi zimatchedwa autosomal recessive.

FMF nthawi zambiri imakhudza anthu ochokera ku Mediterranean. Izi zikuphatikizapo Ayuda omwe si a Ashkenazi (Sephardic) achiyuda, Armenia, ndi Aluya. Anthu ochokera m'mitundu ina amathanso kukhudzidwa.

Zizindikiro nthawi zambiri zimayamba pakati pa zaka 5 ndi 15. Kutupa m'kati mwa m'mimba, pachifuwa, pakhungu, kapena m'malo olumikizana kumachitika limodzi ndi malungo akulu omwe nthawi zambiri amakhala okwera maola 12 mpaka 24. Kuukira kumatha kusiyanasiyana pakukula kwa zizindikilo. Anthu nthawi zambiri amakhala opanda zizindikilo pakati pa ziwopsezo.

Zizindikiro zimaphatikizaponso magawo obwereza a:

• Kupweteka m'mimba
• Kupweteka pachifuwa komwe kumakhala kwakuthwa ndipo kumawonjezeka mukamapuma
• Kutentha thupi kapena kusinthasintha kwa malungo
• Ululu wophatikizana
• Zilonda zapakhungu (zotupa) zomwe ndizofiyira komanso zotupa ndipo zimayambira 5 mpaka 20 cm m'mimba mwake

Ngati kuyezetsa magazi kumawonetsa kuti muli ndi MEFV kusintha kwa majini ndipo zizindikilo zanu zikugwirizana ndi momwe zimakhalira, matendawa ndiotsimikizika. Kuyezetsa magazi kapena ma x-ray kumatha kuthana ndi matenda ena omwe angatithandizire kudziwa.

Miyezo yoyeserera magazi imatha kukhala yayikulu kuposa yachibadwa ikachitika panthawi yozunzidwa. Mayeso atha kuphatikiza:

• Kuwerengera kwathunthu kwa magazi (CBC) komwe kumaphatikizira kuchuluka kwama cell oyera
• Mapuloteni othandizira C kuti ayang'ane kutupa
• Erythrocyte sedimentation rate (ESR) kuti ayang'ane kutupa
• Mayeso a fibrinogen kuti muwone ngati magazi akutseka

Cholinga cha chithandizo cha FMF ndikuwongolera zizindikilo. Colchicine, mankhwala omwe amachepetsa kutupa, atha kuthandizanso pakuukiridwa ndipo amatha kupewa kuukira kwina. Zitha kuthandizanso kupewa zovuta zazikulu zotchedwa systemic amyloidosis, zomwe zimafala kwa anthu omwe ali ndi FMF.

Ma NSAID atha kugwiritsidwa ntchito kuthana ndi malungo ndi ululu.

Palibe mankhwala odziwika a FMF. Anthu ambiri amapitilizabe kuzunzidwa, koma kuchuluka ndi kuopsa kwa ziwopsezo ndizosiyana ndi munthu ndi munthu.

Amyloidosis itha kubweretsa kuwonongeka kwa impso kapena kulephera kuyamwa michere kuchokera pachakudya (malabsorption). Mavuto obereka mwa amayi ndi abambo komanso nyamakazi ndizovuta.

Lumikizanani ndi omwe amakupatsani ngati inu kapena mwana wanu muli ndi zizindikilo za vutoli.

Wodziwika paroxysmal polyserositis; Nthawi peritonitis; Pafupifupi polyserositis; Benign paroxysmal peritonitis; Matenda a nthawi; Kutentha thupi; FMF

• Kuyeza kwa kutentha

Zolemba JW. Tizilombo toyambitsa matenda timene timatulutsa malungo ndi matenda ena oteteza thupi. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 188.

Kutentha kwa Shohat M. Mu: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, olemba. Zowonjezera [Intaneti]. University of Washington, Seattle, WA: 2000 Aug 8 [yasinthidwa 2016 Dec 15]. PMID: 20301405 www.pubmed.ncbi.nlm.nih.gov/20301405/.