Ndemanga ya analgesic

Analgesic nephropathy imakhudza kuwonongeka kwa impso imodzi kapena zonse ziwiri zomwe zimadza chifukwa chakuwonetsedwa mopitilira muyeso wa zosakaniza zamankhwala, makamaka mankhwala opweteka kwambiri (analgesics).

Analgesic nephropathy imakhudza kuwonongeka kwa mkati mwa impso. Amayamba chifukwa chogwiritsa ntchito ma analgesics (mankhwala opweteka) kwakanthawi, makamaka mankhwala owonjezera pa-counter (OTC) omwe ali ndi phenacetin kapena acetaminophen, komanso mankhwala osagwiritsa ntchito anti-inflammatory (NSAIDs), monga aspirin kapena ibuprofen.

Matendawa amapezeka pafupipafupi chifukwa chodzichiritsa, nthawi zambiri amamva kupweteka kosalekeza.

Zowopsa ndi izi:

• Kugwiritsa ntchito ma analgesics a OTC okhala ndi zinthu zopitilira chimodzi
• Kumwa mapiritsi 6 kapena kupitilira apo patsiku kwa zaka zitatu
• Mutu wosatha, msambo wowawa, kupweteka kwa msana, kapena kupweteka kwa minofu
• Kusintha kwamalingaliro kapena kakhalidwe
• Mbiri yazikhalidwe zomwe zimadalira kuphatikiza kusuta, kumwa mowa, komanso kugwiritsa ntchito mopitilira muyeso zinthu zopewetsa nkhawa

Sipangakhale zisonyezo pachiyambi. Popita nthawi, impso zikavulala ndi mankhwala, zizindikilo za matenda a impso zidzayamba, kuphatikizapo:

• Kutopa, kufooka
• Kuchulukitsa kwamikodzo kapena kufulumira
• Magazi mkodzo
• Kumva kupweteka kumbuyo kapena kupweteka kwa msana
• Kuchepetsa mkodzo
• Kuchepetsa kuchepa, kuphatikiza kuwodzera, kusokonezeka, ndi ulesi
• Kuchepetsa kutengeka, dzanzi (makamaka m'miyendo)
• Nseru, kusanza
• Kuvulaza kosavuta kapena kutuluka magazi
• Kutupa (edema) mthupi lonse

Wothandizira zaumoyo adzakufunsani ndikufunsani za matenda anu. Pakati pa mayeso, omwe amakupatsani akhoza kupeza:

• Kuthamanga kwa magazi kwanu ndikokwera.
• Mukamamvetsera ndi stethoscope, mtima wanu ndi mapapo zimakhala ndi mawu osazolowereka.
• Mukutupa, makamaka m'miyendo yakumunsi.
• Khungu lanu limasonyeza kukalamba msanga.

Mayeso omwe angachitike ndi awa:

• Kuwerengera kwathunthu kwa magazi
• Kujambula kwa CT kwa impso
• Mitsempha yotchedwa pyelogram (IVP)
• Chophimba cha Toxicology
• Kupenda kwamadzi
• Impso ultrasound

Zolinga zazikulu zamankhwala ndikuteteza kuwonongeka kwa impso ndikuchiza impso. Wothandizira anu akhoza kukuwuzani kuti musiye kumwa mankhwala okayikitsa, makamaka mankhwala a OTC.

Pofuna kuthandizira kulephera kwa impso, omwe amakupatsani mwayi atha kupereka lingaliro lamasinthidwe azakudya ndikuletsa kwamadzimadzi. Pambuyo pake, dialysis kapena impso kumuika kungakhale kofunikira.

Uphungu ungakuthandizeni kupanga njira zina zothetsera ululu wosatha.

Kuwonongeka kwa impso kungakhale koopsa komanso kwakanthawi, kapena kwanthawi yayitali komanso kwakanthawi.

Zovuta zomwe zingachitike chifukwa cha analgesic nephropathy ndi monga:

• Pachimake impso kulephera
• Kulephera kwa impso
• Matenda a impso pomwe mipata yapakati pa mawere a impso yatupa (interstitial nephritis)
• Kufa kwamatenda m'malo omwe mipata yotolera imalowa mu impso ndi komwe mkodzo umadutsa mu ureters (aimpso papillary necrosis)
• Matenda a mkodzo omwe akupitilirabe kapena amabwereranso
• Kuthamanga kwa magazi
• Khansa ya impso kapena ureter

Itanani omwe akukuthandizani ngati muli ndi izi:

• Zizindikiro za nephropathy ya analgesic, makamaka ngati mwakhala mukugwiritsa ntchito mankhwala opweteka kwa nthawi yayitali
• Magazi kapena zinthu zolimba mumkodzo wanu
• Kuchuluka kwa mkodzo wanu kwatsika

Tsatirani malangizo a omwe amakupatsani mukamagwiritsa ntchito mankhwala, kuphatikiza mankhwala a OTC. Musatenge zochulukirapo kuposa momwe mungafunire popanda kufunsa omwe akukuthandizani.

Phenacetin nephritis; Nephropathy - mankhwala opha ululu

• Matenda a impso

Aronson JK. Paracetamol (acetaminophen) ndi kuphatikiza. Mu: Aronson JK, olemba. Zotsatira zoyipa za Meyler za Mankhwala Osokoneza bongo. Wolemba 16. Waltham, MA: Zotsalira; 2016: 474-493.

Parazella MA, Rosner MH. Matenda a tubulointerstitial. Mu: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, olemba. Brenner ndi Rector a Impso. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 35.

Segal MS, Yu X. Mankhwala azitsamba ndi owonjezera komanso impso. Mu: Feehally J, Floege J, Tonelli M, Johnson RJ, olemba. Chachikulu Chachipatala Nephrology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2019: mutu 76.