Kuchepa kwa magazi m'thupi

Kuchepa kwa magazi m'thupi ndimomwe thupi limakhala lilibe maselo ofiira okwanira okwanira. Maselo ofiira ofiira amapereka mpweya kumatenda amthupi. Pali mitundu yambiri ya kuchepa kwa magazi m'thupi.

Kuchepa kwa magazi ndikuchepa kwamagazi ofiira omwe amapezeka pomwe matumbo samatha kuyamwa vitamini B12 moyenera.

Kuchepa kwa magazi m'thupi ndi mtundu wa kuchepa kwa vitamini B12. Thupi limafunikira vitamini B12 kuti lipange maselo ofiira. Mumapeza vitamini iyi pakudya zakudya monga nyama, nkhuku, nkhono, mazira, ndi mkaka.

Puloteni yapadera, yotchedwa intrinsic factor (IF), imamanga vitamini B12 kuti izitha kulowa m'matumbo. Puloteni iyi imatulutsidwa ndimaselo m'mimba. Pamene m'mimba mulibe chokwanira chokwanira, matumbo samatha kuyamwa vitamini B12 moyenera.

Zomwe zimayambitsa kuchepa kwa magazi m'thupi ndi monga:

• Zofooka m'mimba (atrophic gastritis)
• Mkhalidwe wodziyimira wokha momwe chitetezo cha mthupi chimagwirira ntchito puloteni weniweni wamkati kapena maselo amkati mwa mimba yanu omwe amapanga.

Nthawi zambiri, kuchepa kwa magazi m'thupi kumadutsa m'mabanja. Izi zimatchedwa kobadwa nako koopsa. Ana omwe ali ndi kuchepa kwa magazi kotere samapanga zinthu zofunikira mokwanira. Kapenanso sangathe kuyamwa vitamini B12 m'matumbo ang'onoang'ono.

Kwa akuluakulu, zizindikiro za kuchepa kwa magazi m'thupi nthawi zambiri sizimawoneka mpaka atakwanitsa zaka 30. Zaka zapakati pazomwe amapezeka ndi zaka 60.

Mutha kukhala ndi matendawa ngati:

• Ndi aku Scandinavia kapena Northern Europe
• Khalani ndi mbiriyakale yabanja zikhalidwezo

Matenda ena amathanso kukulitsa chiopsezo. Zikuphatikizapo:

• Matenda a Addison
• Matenda amanda
• Hypoparathyroidism
• Matenda osokoneza bongo
• Myasthenia gravis
• Kutaya ntchito yabwinobwino m'mimba mwake musanakwanitse zaka 40 (kulephera koyambira kwamazira)
• Type 1 shuga
• Kulephera kwa testicular
• Vitiligo
• Matenda a Sjögren
• Matenda a Hashimoto
• Matenda a Celiac

Kuchepetsa magazi m'thupi kumathanso kuchitika pambuyo pochita opaleshoni ya m'mimba.

Anthu ena alibe zizindikiro. Zizindikiro zingakhale zofatsa.

Zitha kuphatikiza:

• Kutsekula m'mimba kapena kudzimbidwa
• Nseru
• Kusanza
• Kutopa, kusowa mphamvu, kapena kupepuka mutayimirira kapena kuyesetsa
• Kutaya njala
• Khungu loyera (jaundice wofatsa)
• Kupuma pang'ono, makamaka panthawi yochita masewera olimbitsa thupi
• Kutentha pa chifuwa
• Kutupa, lilime lofiira kapena chingamu chotuluka magazi

Ngati muli ndi mavitamini B12 ochepa kwa nthawi yayitali, mutha kuwonongeka kwamanjenje. Zizindikiro zimatha kuphatikiza:

• Kusokonezeka
• Kutaya kwakanthawi kochepa
• Matenda okhumudwa
• Kutaya malire
• Dzanzi ndi kumva kulasalasa m'manja ndi m'mapazi
• Mavuto akukhazikika
• Kukwiya
• Ziwerengero
• Zonyenga
• Optic mitsempha ya manja

Wothandizira zaumoyo adzayesa. Mayeso omwe angachitike ndi awa:

• Kuyezetsa magazi a mafupa (kumangofunika ngati matendawa sadziwika)
• Kuwerengera kwathunthu kwa magazi (CBC)
• Kuwerengera kwa reticulocyte
• Mulingo wa LDH
• Seramu bilirubin
• Mlingo wa Methylmalonic acid (MMA)
• Mulingo wa homocysteine ​​(amino acid wopezeka m'magazi)
• Mulingo wa Vitamini B12
• Mulingo wa ma antibodies olimbana ndi IF kapena maselo omwe amapanga IF

Cholinga cha chithandizo ndikuwonjezera kuchuluka kwanu kwa vitamini B12:

• Chithandizo chimaphatikizapo kuwombera vitamini B12 kamodzi pamwezi. Anthu omwe ali ndi B12 yotsika kwambiri angafunike kuwombera kambiri pachiyambi.
• Anthu ena amatha kuchiritsidwa mokwanira akamamwa mankhwala ambiri a vitamini B12 pakamwa.
• Mtundu wina wa vitamini B12 ungaperekedwe kudzera m'mphuno.

Anthu ambiri nthawi zambiri amachita bwino ndi chithandizo chamankhwala.

Ndikofunika kuyamba kumwa mankhwala msanga. Kuwonongeka kwa mitsempha kumatha kukhala kosatha ngati mankhwala sayamba mkati mwa miyezi 6 yazizindikiro.

Anthu omwe ali ndi kuchepa kwa magazi m'thupi amatha kukhala ndi tizilombo toyambitsa matenda m'mimba. Amakhalanso ndi khansa ya m'mimba komanso zotupa za khansa m'mimba.

Anthu omwe ali ndi vuto la kuchepa kwa magazi m'thupi amakhala ndi zotupa zakumbuyo, mwendo wapamwamba, ndi mkono wapamwamba.

Mavuto aubongo ndi mitsempha atha kupitilirabe kapena kukhala okhazikika ngati mankhwala akuchedwa.

Mzimayi yemwe ali ndi mulingo wochepa wa B12 atha kukhala ndi kachilombo koyipa ka Pap smear. Izi ndichifukwa choti kuchepa kwa vitamini B12 kumakhudza momwe maselo ena (ma epithelial cell) amawonekera.

Itanani omwe akukuthandizani ngati muli ndi vuto la kuchepa kwa vitamini B12.

Palibe njira yodziwikiratu yochepetsera kuchepa kwa mavitamini B12. Komabe, kuzindikira msanga ndi chithandizo kumatha kuchepetsa zovuta.

Macrocytic achylic kuchepa kwa magazi; Kobadwa nako koopsa kwa magazi m'thupi; Matenda owopsa a ana; Kulephera kwa Vitamini B12 (malabsorption); Kuchepa kwa magazi m'thupi - chinthu chofunikira; Kuchepa kwa magazi - IF; Kuchepa magazi - atrophic gastritis; Kuchepa kwa magazi kwa Biermer; Addison kuchepa kwa magazi

• Anemia of Megaloblastic - kuwona kwa maselo ofiira ofiira

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Anusha V. Kuchepa kwa magazi m'thupi / megaloblastic anemia. Mu: Kellerman RD, Rakel DP, olemba., Eds. Therapy Yamakono ya Conn 2020. Philadelphia, PA: Elsevier; 2020: 446-448.

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