Mlembi: Marcus Baldwin
Tsiku La Chilengedwe: 20 Kuni 2021
Sinthani Tsiku: 25 Okotobala 2024
Anonim
Angapo dongosolo atrophy - cerebellar subtype - Mankhwala
Angapo dongosolo atrophy - cerebellar subtype - Mankhwala

Multiple system atrophy - cerebellar subtype (MSA-C) ndi matenda osowa omwe amachititsa madera ozama muubongo, pamwamba pa msana, kuchepa. MSA-C amadziwika kuti olivopontocerebellar atrophy (OPCA).

MSA-C ikhoza kupitilizidwa kudzera m'mabanja (mawonekedwe obadwa nawo). Zitha kukhudzanso anthu omwe alibe mbiri yodziwika ya banja (mawonekedwe owonekera).

Ofufuza apeza majini ena omwe amakhudzidwa ndi vuto lobadwa nalo.

Zomwe zimayambitsa MSA-C mwa anthu omwe ali ndi mawonekedwe ochepa sizidziwika. Matendawa amafika pang'onopang'ono (akupita patsogolo).

MSA-C imadziwika kwambiri mwa amuna kuposa akazi. Avereji ya zaka zoyambira ali ndi zaka 54.

Zizindikiro za MSA-C zimayamba kuyambira ali aang'ono mwa anthu omwe ali ndi mawonekedwe obadwa nawo. Chizindikiro chachikulu ndikubanika (ataxia) komwe kumangokulira. Pakhoza kukhalanso ndi mavuto pochepetsa, kuyankhula molakwika, komanso kuyenda movutikira.

Zizindikiro zina zitha kuphatikiza:

  • Kusuntha kwamaso kosazolowereka
  • Kusuntha kosazolowereka
  • Matumbo kapena chikhodzodzo
  • Zovuta kumeza
  • Manja ozizira ndi mapazi
  • Mutu wopepuka mukaimirira
  • Kupweteka mutu ataimirira komwe kumasulidwa ndi kugona pansi
  • Kuuma kwa minofu kapena kuuma, kupindika, kunjenjemera
  • Kuwonongeka kwa mitsempha (neuropathy)
  • Mavuto polankhula ndi kugona chifukwa cha kukanika kwa zingwe zamawu
  • Mavuto ogwirira ntchito
  • Thukuta losazolowereka

Kuwunika mokwanira zamankhwala ndi zamanjenje, komanso kuwunika chizindikiro ndi mbiri ya banja ndizofunikira kuti adziwe.


Pali mayeso amtundu wofufuza zomwe zimayambitsa matenda ena. Koma, palibe mayeso enieni omwe amapezeka nthawi zambiri. MRI yaubongo imatha kuwonetsa kusintha kwa kukula kwa maubongo okhudzidwa, makamaka matendawa akukulira. Koma ndizotheka kukhala ndi vuto ndikukhala ndi MRI yabwinobwino.

Mayesero ena monga positron emission tomography (PET) atha kuchitidwa kuti athetse zina. Izi zingaphatikizepo kumeza maphunziro kuti muwone ngati munthu angathe kumeza chakudya ndi madzi.

Palibe mankhwala enieni kapena mankhwala a MSA-C. Cholinga ndikuteteza zizindikilo ndikupewa zovuta. Izi zingaphatikizepo:

  • Mankhwala owopsa, monga a matenda a Parkinson
  • Kulankhula, kugwira ntchito komanso kuchiritsa
  • Njira zopewera kutsamwa
  • Zothandizira kuyenda poyenda moyenera ndikupewa kugwa

Magulu otsatirawa atha kupereka zothandizira ndi chithandizo kwa anthu omwe ali ndi MSA-C:

  • Gonjetsani MSA Alliance - conqumsa.org/patient-programs/
  • Mgwirizano wa MSA - www.multiplesystematrophy.org/msa-resource/

MSA-C imakulirakulirabe, ndipo palibe mankhwala. Maganizo nthawi zambiri amakhala osauka. Koma, zitha kutenga zaka kuti wina akhale wolumala kwambiri.


Mavuto a MSA-C ndi awa:

  • Kutsamwa
  • Kutenga kuchokera pakulowetsa chakudya m'mapapu (aspiration pneumonia)
  • Kuvulala kwakugwa
  • Mavuto a zakudya chifukwa chovuta kumeza

Imbani wothandizira zaumoyo wanu ngati muli ndi zizindikiro za MSA-C. Muyenera kuwonedwa ndi katswiri wa zamagulu. Uyu ndi dokotala yemwe amathandizira mavuto amanjenje.

MSA-C; Cerebellar angapo dongosolo atrophy; Olivopontocerebellar manja; OPCA; Kutha kwa Olivopontocerebellar

  • Central dongosolo lamanjenje ndi zotumphukira zamanjenje

Ciolli L, Krismer F, Nicoletti F, Wenning GK. Zosintha pa cerebellar subtype yamagulu angapo a atrophy. Cerebellum Ataxias. 2014; 1-14. PMID: 26331038 adasankhidwa.ncbi.nlm.nih.gov/26331038/.

Gilman S, Wenning GK, Low PA, et al. (Adasankhidwa) Chigwirizano chachiwiri chokhudza kupezedwa kwa ma system angapo atrophy. Neurology. 2008; 71 (9): 670-676. PMID: 18725592 adatulutsidwa.ncbi.nlm.nih.gov/18725592/.


Matenda a Jancovic J. Parkinson ndi zovuta zina zoyenda. Mu: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, olemba. Neurology ya Bradley mu Kuchita Zachipatala. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2016: chap 96.

Ma MJ. Biopsy pathology of neurodegenerative matenda akuluakulu. Mu: Perry A, DJ wa Brat, olemba. Njira Yothandizira Opaleshoni ya Neuropathology: Njira Yodziwitsa. Wachiwiri ed. Philadelphia, PA: Elsevier, 2018: mutu 27.

Walsh RR, Krismer F, Galpern WR, ndi al. Malangizo a msonkhano wapadziko lonse lapansi wofufuza pamsewu. Neurology. 2018; 90 (2): 74-82. PMID: 29237794 pubed.ncbi.nlm.nih.gov/29237794/.

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