Neurofibromatosis 2

Neurofibromatosis 2 (NF2) ndimatenda momwe zotupa zimapangika m'mitsempha ya ubongo ndi msana (chapakati dongosolo lamanjenje). Zimaperekedwa (kubadwa) m'mabanja.

Ngakhale ili ndi dzina lofanana ndi mtundu 1 wa neurofibromatosis, ndi mtundu wina wosiyana.

NF2 imayambitsidwa ndi kusintha kwa jini NF2. NF2 imatha kupitilizidwa kudzera m'mabanja mofananira autosomal. Izi zikutanthauza kuti ngati kholo limodzi lili ndi NF2, mwana aliyense wa kholoyo ali ndi mwayi wololera vutoli 50%. Zina mwa NF2 zimachitika pamene jini imasintha yokha. Munthu wina akatenga kusintha kwa majini, ana awo amakhala ndi mwayi wolandira cholowa mwa 50%.

Choyipa chachikulu pachiwopsezo ndikukhala ndi mbiri yabanja ya vutoli.

Zizindikiro za NF2 ndi monga:

• Mavuto osamala
• Amayamba kudwala ali mwana
• Zosintha m'masomphenya
• Zizindikiro zofiirira pakhungu (café-au-lait), zosazolowereka
• Kupweteka mutu
• Kutaya kwakumva
• Kulira ndi phokoso m'makutu
• Kufooka kwa nkhope

Zizindikiro za NF2 zikuphatikizapo:

• Zotupa za ubongo ndi msana
• Zotupa zokhudzana ndi kumva (acoustic)
• Zotupa za khungu

Mayeso ndi awa:

• Kuyesedwa kwakuthupi
• Mbiri yazachipatala
• MRI
• Kujambula kwa CT
• Kuyesedwa kwachibadwa

Zotupa zamayimbidwe zimatha kuwonedwa, kapena kuthandizidwa ndi opaleshoni kapena radiation.

Anthu omwe ali ndi vutoli atha kupindula ndi upangiri wa majini.

Anthu omwe ali ndi NF2 ayenera kuyesedwa pafupipafupi ndi mayeso awa:

• MRI yaubongo ndi msana
• Kumva ndi kuwunika koyankhula
• Kuyezetsa maso

Zida zotsatirazi zitha kupereka zambiri pa NF2:

• Tumor ya Ana Foundation - www.ctf.org
• Neurofibromatosis Network - www.nfnetwork.org

NF2; Wapawiri lamayimbidwe lamayimbidwe neurofibromatosis; Magulu awiri opatsirana a schwannomas; Central neurofibromatosis

• Central dongosolo lamanjenje ndi zotumphukira zamanjenje

Sahin M, Ullrich N, Srivastava S, Pinto A. Ma syndromes amtundu wosagwirizana. Mu: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 614.

Slattery WH. Neurofibromatosis 2. Mu: Brackmann DE, Shelton C, Arriaga MA, eds. Opaleshoni ya Otologic. Wolemba 4. Philadelphia, PA: Elsevier; 2016: chap 57.

Varma R, Williams SD. Neurology. Mu: Zitelli BJ, McIntire SC, Nowalk AJ, eds. Zitelli ndi Davis ’Atlas of Pediatric Physical Diagnosis. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 16.