Kulephera kwa Hypothalamic

Kulephera kwa Hypothalamic ndi vuto ndi gawo lina la ubongo lotchedwa hypothalamus. Hypothalamus imathandizira kuwongolera chiberekero cha pituitary ndikuwongolera machitidwe ambiri amthupi.

Hypothalamus imathandiza kuti ntchito zamkati zamthupi zizikhala bwino. Zimathandizira kuwongolera:

• Njala ndi kulemera
• Kutentha kwa thupi
• Kubereka
• Kutengeka, machitidwe, kukumbukira
• Kukula
• Kupanga mkaka wa m'mawere
• Mchere ndi madzi bwino
• Kuyendetsa kugonana
• Kuzungulira-kugona ndi wotchi yamthupi

Ntchito inanso yofunika kwambiri ya hypothalamus ndikuwongolera chithokomiro. Pituitary ndi kansalu kakang'ono m'munsi mwa ubongo. Ili pansi pamunsi pa hypothalamus. Vutoli, limayang'anira:

• Zilonda za adrenal
• Zosunga
• Mayeso
• Chithokomiro

Pali zifukwa zambiri zomwe zimapangitsa kuti munthu asagwire bwino ntchito. Chofala kwambiri ndi maopareshoni, kuvulala koopsa kwaubongo, zotupa, ndi radiation.

Zina mwa zifukwa zake ndi izi:

• Mavuto a zakudya, monga matenda osadya (anorexia), kuonda kwambiri
• Mavuto amitsuko yamagazi muubongo, monga aneurysm, pituitary apoplexy, subarachnoid hemorrhage
• Matenda amtundu, monga Prader-Willi matenda, matenda a shuga am'mabanja, Kallmann syndrome
• Matenda ndi kutupa (kutupa) chifukwa cha matenda ena amthupi

Zizindikiro nthawi zambiri zimakhala chifukwa cha mahomoni kapena maubongo omwe akusowa. Kwa ana, pakhoza kukhala mavuto akukula, mwina kukula kwambiri kapena kuchepa kwambiri. Kwa ana ena, kutha msinkhu kumachitika msanga kapena mochedwa kwambiri.

Zizindikiro zotupa zimaphatikizaponso kupweteka mutu kapena kutaya masomphenya.

Ngati chithokomiro chikukhudzidwa, pakhoza kukhala zizindikilo za chithokomiro chosagwira ntchito (hypothyroidism). Zizindikiro zimatha kuphatikizira kuzizira nthawi zonse, kudzimbidwa, kutopa, kapena kunenepa, pakati pa ena.

Ngati adrenal glands imakhudzidwa, pakhoza kukhala zizindikilo za kuchepa kwa adrenal. Zizindikiro zimaphatikizapo kutopa, kufooka, kusowa chakudya, kuonda, komanso kusachita chidwi ndi zinthu.

Wothandizira zaumoyo adzakufufuza ndikufunsa za zizindikiro zanu.

Mayeso amwazi kapena mkodzo atha kulamulidwa kuti adziwe kuchuluka kwa mahomoni monga:

• Cortisol
• Estrogen
• Hormone yakukula
• Mahomoni am'thupi
• Prolactin
• Testosterone
• Chithokomiro
• Sodium
• Magazi ndi mkodzo osmolality
  

Mayesero ena omwe angakhalepo ndi awa:

• Majakisoni a Hormone otsatiridwa ndi zitsanzo zamagazi nthawi yake
• Kujambula kwa MRI kapena CT kwaubongo
• Kuyesa kwamaso oyang'ana m'maso (ngati pali chotupa)

Chithandizo chimadalira chifukwa cha kusokonekera kwa hypothalamic:

• Kwa zotupa, opaleshoni kapena radiation kungafunike.
• Pakuchepa kwama mahomoni, mahomoni omwe akusowa amafunika kusintha ndikumwa mankhwala. Izi ndizothandiza pamavuto am'mimba, komanso pamchere wamchere ndi madzi.
• Mankhwala nthawi zambiri sagwira ntchito pakusintha kwa kutentha kapena kugona.
• Mankhwala ena amatha kuthandizira pamavuto okhudzana ndi njala.

Zambiri zomwe zimayambitsa vuto la hypothalamic ndizotheka kuchiza. Nthawi zambiri, mahomoni omwe akusowa amatha kusintha.

Zovuta zakusokonekera kwa hypothalamic zimadalira chifukwa.

ZINTHU ZABONGO

• Khungu losatha
• Mavuto okhudzana ndi ubongo komwe chotupacho chimachitika
• Vuto la masomphenya
• Mavuto owongolera mchere ndi madzi

KUSINTHA KWAMBIRI

• Mavuto amtima
• Cholesterol wokwera

KUSAKHULUPIRIRA KWAMBIRI

• Kulephera kuthana ndi kupsinjika (monga opaleshoni kapena matenda), zomwe zitha kupha moyo pochepetsa kuthamanga kwa magazi

KUSOLEKA KWA GEZA GLAND

• Matenda a mtima
• Mavuto okonzekera
• Kusabereka
• Mafupa owonda (kufooka kwa mafupa)
• Mavuto kuyamwitsa

KUKHULUPIRIRA KWA HORMONE

• Cholesterol wokwera
• Kufooka kwa mafupa
• Msinkhu waufupi (mwa ana)
• Kufooka

Itanani omwe akukuthandizani ngati muli ndi:

• Kupweteka mutu
• Zizindikiro za kuchuluka kwa mahomoni kapena kuchepa
• Mavuto masomphenya

Ngati muli ndi zizindikilo zakusowa kwa mahomoni, kambiranani ndi omwe akukuthandizani.

Ma syndromes a Hypothalamic

• Central dongosolo lamanjenje ndi zotumphukira zamanjenje
• Hypothalamus

Giustina A, Braunstein GD. Ma syndromes a Hypothalamic. Mu: Jameson JL, De Groot LJ, de Kretser DM, et al, olemba. Endocrinology: Akuluakulu ndi Ana. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier Saunders; 2016: mutu 10.

Weiss RE. Neuroendocrinology ndi dongosolo la neuroendocrine. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: mutu 210.