Matenda oopsa a hyperthermia

Malignant hyperthermia (MH) ndimatenda omwe amachititsa kuti thupi liziziziritsa kwambiri komanso kuti thupi likhale ndi minyewa yambiri munthu amene ali ndi MH atapeza mankhwala ochititsa dzanzi. MH imadutsa kudzera m'mabanja.

Hyperthermia amatanthauza kutentha kwa thupi. Vutoli silofanana ndi hyperthermia yochokera kuzadzidzidzi zamankhwala monga kutentha thupi kapena matenda.

MH amatengera cholowa. Ndi kholo limodzi lokha lomwe liyenera kunyamula matendawa kuti mwana adzalandire vutoli.

Zitha kuchitika ndi matenda ena amtundu wobadwa nawo, monga multiminicore myopathy ndi matenda apakati.

Zizindikiro za MH ndizo:

• Magazi
• Mkodzo wofiirira wakuda (chifukwa cha mapuloteni amtundu wotchedwa myoglobin mu mkodzo)
• Kupweteka kwa minofu popanda chifukwa chomveka, monga kuchita masewera olimbitsa thupi kapena kuvulala
• Kuuma kwa minofu ndi kuuma
• Kwezani kutentha kwa thupi mpaka 105 ° F (40.6 ° C) kapena kupitilira apo

MH imapezeka nthawi zambiri munthu akapatsidwa mankhwala ochititsa dzanzi pa opaleshoni.

Pakhoza kukhala mbiri yabanja ya MH kapena imfa yosadziwika panthawi ya anesthesia.

Munthuyo amatha kugunda kwamtima mwachangu komanso nthawi zambiri.

Mayeso a MH atha kuphatikizira:

• Maphunziro a magazi (PT, kapena prothrombin nthawi; PTT, kapena nthawi yapadera ya thromboplastin)
• Gulu lamagetsi am'magazi, kuphatikiza CK (creatinine kinase, yomwe imakwera kwambiri m'magazi minofu ikawonongeka panthawi yakudwala)
• Kuyesedwa kwa majini kuti ayang'ane zolakwika m'matenda omwe amalumikizidwa ndi matendawa
• Kutulutsa minofu
• Mkodzo myoglobin (protein protein)

Panthawi ya MH, mankhwala otchedwa dantrolene amaperekedwa nthawi zambiri. Kukutira munthuyo mu bulangeti lozizira kumatha kuchepetsa kutentha thupi komanso chiopsezo cha zovuta zina.

Kusunga magwiridwe antchito a impso panthawi inayake, munthuyo amatha kulandira madzi kudzera mumitsempha.

Izi zitha kukupatsirani zambiri za MH:

• Malignant Hyperthermia Association ku United States - www.mhaus.org
• National Organisation for Rare Disways - rarediseases.org/rare-diseases/malignant-hyperthermia
• Buku Lofotokozera la NIH Genetics - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Magawo obwerezedwa kapena osachiritsidwa amatha kuyambitsa impso. Magawo osachiritsidwa amatha kupha.

Zovuta zazikuluzi zitha kuchitika:

• Kudulidwa
• Kuwonongeka kwa minofu ya minofu
• Kutupa kwa manja ndi mapazi komanso mavuto am'magazi komanso magwiridwe antchito (compartment syndrome)
• Imfa
• Kutseka magazi kosazolowereka komanso kutuluka magazi
• Mavuto amtundu wamtima
• Impso kulephera
• Kupanga kwa asidi m'madzi amthupi (metabolic acidosis)
• Kutsekemera kwamadzimadzi m'mapapu
• Minofu yofooka kapena yopunduka (myopathy kapena muscular dystrophy)

Ngati mukufuna kuchitidwa opaleshoni, uzani dokotala wanu komanso dotolo musanachite opaleshoni ngati:

• Mukudziwa kuti inu kapena wachibale wanu mwakhala mukukumana ndi vuto la anesthesia
• Mukudziwa muli ndi mbiri yabanja ya MH

Kugwiritsa ntchito mankhwala ena kumatha kupewa zovuta za MH panthawi yochita opaleshoni.

Uzani wothandizira zaumoyo wanu musanachite opaleshoni ndi anesthesia, ngati inu kapena aliyense m'banja lanu muli ndi MH.

Pewani mankhwala osokoneza bongo monga cocaine, amphetamine (liwiro), ndi chisangalalo. Mankhwalawa atha kubweretsa mavuto ofanana ndi a MH mwa anthu omwe amakonda kuchita izi.

Upangiri wa majeremusi amalimbikitsidwa kwa aliyense amene ali ndi mbiri ya banja la myopathy, muscular dystrophy, kapena MH.

Hyperthermia - yoyipa; Hyperpyrexia - yoyipa; MH

American Association of Namwino Anesthetists. Kukonzekera koopsa kwa hyperthermia kukonzekera ndi chithandizo: kufotokozera udindo. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Idasinthidwa mu Epulo 2018. Idapezeka pa Meyi 6, 2019.

Kulaylat MN, Dayton MT. Matenda opangira opaleshoni. Mu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Buku Lopanga Opaleshoni. Wolemba 20th. Philadelphia, PA: Elsevier; 2017: mutu 12.

Zhou J, Bose D, Allen PD, Pessah IN. (Adasankhidwa) Matenda oopsa a hyperthermia ndi zovuta zokhudzana ndi minofu. Mu: Miller RD, Mkonzi. Anesthesia wa Miller. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015: chap 43.