Mapuloteni othandizira C
C-reactive protein (CRP) imapangidwa ndi chiwindi. Mulingo wa CRP umakwera pakakhala kutupa mthupi lonse. Ndi limodzi mwamapuloteni omwe amatchedwa pachimake phase reactants omwe amapita chifukwa cha kutupa. Magawo azigawo zoyipa amawonjezeka chifukwa cha mapuloteni ena otupa otchedwa cytokines. Mapuloteniwa amapangidwa ndi maselo oyera a magazi panthawi yotupa.
Nkhaniyi ikufotokoza za kuyesa magazi komwe kwachitika kuti muyeza kuchuluka kwa CRP m'magazi anu.
Muyenera kuyesa magazi. Izi nthawi zambiri zimatengedwa kuchokera mumtsempha. Njirayi imatchedwa venipuncture.
Palibe njira zofunikira pakukonzekera mayesowa.
Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kuti amangobaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupindika.
Kuyesa kwa CRP ndiyeso yayikulu yowunika kutupa m'thupi. Si mayeso enieni. Izi zikutanthauza kuti zitha kuwulula kuti muli ndi kutupa kwinakwake mthupi lanu, koma silingathe kudziwa komwe kuli. Mayeso a CRP nthawi zambiri amachitidwa ndi ESR kapena sedimentation test test yomwe imayang'ananso kutupa.
Mutha kukhala ndi mayeso awa ku:
- Fufuzani matenda opatsirana monga nyamakazi, lupus, kapena vasculitis.
- Dziwani ngati mankhwala odana ndi zotupa akugwira ntchito yothandizira matenda kapena vuto.
Komabe, kutsika kwa CRP sikutanthauza nthawi zonse kuti kulibe kutupa komwe kulipo. Mipata ya CRP siyingakulitsidwe mwa anthu omwe ali ndi nyamakazi ndi lupus. Chifukwa cha ichi sichikudziwika.
Kuyezetsa kovuta kwa CRP, kotchedwa protein-c-reactive protein (hs-CRP) kuyesa, kumapezeka kuti kuzindikiritse chiwopsezo cha munthu cha matenda amtima.
Makhalidwe abwinobwino a CRP amasiyanasiyana kuchokera ku labu mpaka lab. Nthawi zambiri, pali magawo otsika a CRP omwe amapezeka m'magazi. Magawo nthawi zambiri amakula pang'ono ndi ukalamba, akazi komanso ku Africa America.
Kuwonjezeka kwa seramu CRP kumakhudzana ndi ziwopsezo zamatenda amtima ndipo zitha kuwonetsa zomwe zimayambitsa izi zomwe zimayambitsa kutupa kwamitsempha.
Malinga ndi American Heart Association, zotsatira za hs-CRP pozindikira chiwopsezo cha matenda amtima zitha kutanthauziridwa motere:
- Muli pachiwopsezo chochepa chokhala ndi matenda amtima ngati hs-CRP yanu ndiyotsika kuposa 1.0 mg / L.
- Muli pachiwopsezo chotenga matenda amtima ngati magawo anu ali pakati pa 1.0 mg / L ndi 3.0 mg / L.
- Muli pachiwopsezo chachikulu cha matenda amtima ngati hs-CRP yanu ndiyokwera kuposa 3.0 mg / L.
Chidziwitso: Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pama laboratories osiyanasiyana. Lankhulani ndi wothandizira zaumoyo wanu za tanthauzo la zotsatira zanu zoyeserera.
Zitsanzo pamwambapa zikuwonetsa muyeso wamba wazotsatira zamayesowa. Ma labotale ena amagwiritsa ntchito miyeso yosiyana kapena amatha kuyesa mitundu yosiyanasiyana.
Kuyesedwa koyenera kumatanthauza kuti muli ndi kutupa mthupi. Izi zitha kukhala chifukwa cha zinthu zosiyanasiyana, kuphatikiza:
- Khansa
- Matenda othandizira
- Matenda amtima
- Matenda
- Matenda otupa (IBD)
- Lupus
- Chibayo
- Matenda a nyamakazi
- Rheumatic malungo
- Matenda a chifuwa chachikulu
Mndandanda uwu suli wonse.
Chidziwitso: Zotsatira zabwino za CRP zimapezekanso theka lakumapeto kwa mimba kapena kugwiritsa ntchito mapiritsi (njira zolera zokometsera).
Zowopsa zomwe zimakhudza kukoka magazi ndizochepa, koma zimatha kuphatikiza:
- Kutaya magazi kwambiri
- Kukomoka kapena kumva mopepuka
- Hematoma (magazi akuchuluka pansi pa khungu)
- Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)
CRP; Mapuloteni otsogola kwambiri a C; hs-CRP
- Kuyezetsa magazi
Chernecky CC, Berger BJ. C. Mu: Chernecky CC, Berger BJ, olemba. Kuyesa Kwantchito ndi Njira Zakuzindikira. Lachisanu ndi chimodzi. St Louis, MO: Elsevier Saunders; 2013: 266-432.
Zakudya DJ. Amino acid, peptides, ndi mapuloteni. Mu: Rifai N, mkonzi. Tietz Textbook of Clinical Chemistry ndi Molecular Diagnostics. Lachisanu ndi chimodzi. St Louis, MO: Elsevier; 2018: mutu 28.
Ridker PM, Libby P, Kulipira JE. Zizindikiro zowopsa komanso kupewa koyambirira kwamatenda amtima. Mu: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2019: mutu 45.