Rheumatoid factor (RF)

Rheumatoid factor (RF) ndi kuyesa magazi komwe kumayeza kuchuluka kwa anti-RF m'magazi.

Nthawi zambiri, magazi amatengedwa pamitsempha yomwe ili mkati mwa chigongono kapena kumbuyo kwa dzanja.

Kwa makanda kapena ana aang'ono, chida chakuthwa chotchedwa lancet chitha kugwiritsidwa ntchito kuboola khungu.

• Mwazi umasonkhanitsa mu chubu chaching'ono chagalasi chotchedwa pipette, kapena pa slide kapena mzere woyesera.
• Bandeji amaikidwa pamalopo kuti athetse magazi.

Nthawi zambiri, simusowa kuti muchitepo kanthu musanayesedwe.

Mutha kumva kupweteka pang'ono kapena mbola pamene singano imayikidwa. Muthanso kumva kupwetekedwa pamalowo magazi atatengedwa.

Mayesowa amagwiritsidwa ntchito kwambiri kuthandizira matenda a nyamakazi kapena matenda a Sjögren.

Zotsatira zimanenedwa m'njira imodzi mwanjira ziwiri izi:

• Mtengo, wabwinobwino zosakwana 15 IU / mL
• Nthawi, yosakwana 1:80 (1 mpaka 80)

Zotsatira zake zili pamwambapa, ndizabwino. Chiwerengero chotsika (zotsatira zoyipa) nthawi zambiri chimatanthauza kuti mulibe nyamakazi kapena matenda a Sjögren. Komabe, anthu ena omwe ali ndi izi ali ndi RF yoyipa kapena yotsika.

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Lankhulani ndi wothandizira zaumoyo wanu za tanthauzo la zotsatira zanu zoyeserera.

Zotsatira zosazolowereka zikutanthauza kuti mayesowo ndiabwino, zomwe zikutanthauza kuti mulingo wapamwamba wa RF wapezeka m'magazi anu.

• Anthu ambiri omwe ali ndi nyamakazi kapena matenda a Sjögren amakhala ndi mayeso abwino a RF.
• Kutalika kwa msinkhu, nthawi zambiri chimodzi mwazimenezi zilipo. Palinso mayesero ena pazovuta izi zomwe zimathandizira kuti azindikire.
• Sikuti aliyense amene ali ndi mulingo wapamwamba wa RF ali ndi nyamakazi kapena matenda a Sjögren.

Wothandizira anu ayeneranso kuyesa magazi (anti-CCP antibody), kuti athandizire kupeza nyamakazi (RA). Antibodi ya anti-CCP ndiyodziwika bwino kwa RA kuposa RF. Kuyesedwa koyenera kwa anti-CCP kumatanthauza kuti RA mwina ndi matenda oyenera.

Anthu omwe ali ndi matenda otsatirawa amathanso kukhala ndi ma RF apamwamba:

• Chiwindi C
• Njira lupus erythematosus
• Dermatomyositis ndi polymyositis
• Sarcoidosis
• Cryoglobulinemia wosakanikirana
• Matenda osakanikirana

Miyezo yoposa yachibadwa ya RF imatha kuwonedwa mwa anthu omwe ali ndi mavuto ena azachipatala. Komabe, milingo yayikulu iyi ya RF siyingagwiritsidwe ntchito kuzindikira matenda enawa:

• Edzi, matenda a chiwindi, fuluwenza, mononucleosis yopatsirana, ndi matenda ena a ma virus
• Matenda ena a impso
• Endocarditis, chifuwa chachikulu, ndi matenda ena a bakiteriya
• Matenda a tiziromboti
• Khansa ya m'magazi, myeloma yambiri, ndi khansa zina
• Matenda am'mapapo
• Matenda a chiwindi

Nthawi zina, anthu omwe ali ndi thanzi labwino ndipo alibe vuto lina lililonse lazachipatala amakhala ndi mulingo woposa RF.

• Kuyezetsa magazi

Aletaha D, Neogi T, Silman AJ, ndi al. Zotsatira za 2010 za nyamakazi: American College of Rheumatology / European League Against Rheumatism yothandizana nayo. Ann Rheum Dis. 2010; 69 (9): 1580-1588. PMID: 20699241 www.ncbi.nlm.nih.gov/pubmed/20699241.

Andrade F, Darrah E, Rosen A. Autoantibodies m'matenda a nyamakazi. Mu: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, olemba. Kelley ndi Firestein's Bookbook of Rheumatology. 10th ed. Philadelphia, PA: Elsevier; 2017: mutu 56.

Hoffmann MH, Trouw LA, Steiner G. Autoantibodies mu nyamakazi ya nyamakazi. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, olemba. Zamatsenga. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2019: mutu 99.

Mason JC. Rheumatic matenda ndi mtima dongosolo. Mu: Zipes DP, Libby P, Bonow RO, Mann, DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2019: mutu 94.

Pisetsky DS. Kuyesa kwa Laborator mu rheumatic matenda. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 257.

von Mühlen CA, Fritzler MJ, Chan EKL. Kuyesa kwamankhwala ndi labotale kwamatenda amtundu wa system. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 52.