Matenda a Helicobacter pylori

Helicobacter pylori (H pylori) ndi mtundu wa mabakiteriya omwe amapatsira m'mimba. Ndizofala kwambiri, zomwe zimakhudza pafupifupi magawo awiri mwa atatu mwa anthu padziko lapansi. H pylori Matendawa ndi omwe amayambitsa zilonda zam'mimba. Komabe, matendawa samabweretsa mavuto kwa anthu ambiri.

H pylori Mabakiteriya amatha kudutsa mwachindunji kuchokera kwa munthu kupita kwa munthu. Izi zimakonda kuchitika ali mwana. Matendawa amakhalabe moyo wonse ngati sanalandire chithandizo.

Sizikudziwika bwino momwe mabakiteriya amapatsira kuchokera kwa munthu wina kupita kwa mnzake. Mabakiteriya amatha kufalikira kuchokera:

• Kuyanjana pakamwa
• Matenda a GI (makamaka kusanza kumachitika)
• Lumikizanani ndi chopondapo (chimbudzi)
• Chakudya ndi madzi owonongeka

Mabakiteriya amatha kuyambitsa zilonda motere:

• H pylori imalowa mumatumbo am'mimba ndikumata m'mimba.
• H pylori zimapangitsa m'mimba kutulutsa asidi wam'mimba wambiri. Izi zimawononga m'mimba, zomwe zimayambitsa zilonda mwa anthu ena.

Kupatula zilonda, H pylori Mabakiteriya amathanso kuyambitsa kutupa kwam'mimba (gastritis) kapena kumtunda kwa m'mimba (duodenitis).

H pylori Nthawi zina zimatha kubweretsa khansa yam'mimba kapena mtundu wosavomerezeka wam'mimba lymphoma.

Pafupifupi 10% mpaka 15% ya anthu omwe ali ndi kachilomboka H pylori khalani ndi zilonda zam'mimba. Zilonda zazing'ono sizingayambitse zizindikiro zilizonse. Zilonda zina zimatha kutulutsa magazi kwambiri.

Kupweteka kapena kutentha m'mimba mwanu ndi chizindikiro chofala. Ululu ukhoza kukulirakulira ndi m'mimba mopanda kanthu. Kupwetekako kumatha kusiyanasiyana munthu ndi munthu, ndipo anthu ena alibe zopweteka.

Zizindikiro zina ndizo:

• Kumva kukhuta kapena kudzimbidwa ndi mavuto akumamwa madzi ochuluka monga mwachizolowezi
• Njala komanso kumverera kopanda kanthu m'mimba, nthawi zambiri 1 mpaka 3 maola mutadya
• Mseru wofatsa womwe ungachoke ndikusanza
• Kutaya njala
• Kuchepetsa thupi osayesa
• Kuphulika
• Magazi kapena mdima, malo odikira kapena masanzi amwazi

Wothandizira zaumoyo wanu adzakuyesani H pylori ngati:

• Khalani ndi zilonda zam'mimba kapena mbiri ya zilonda zam'mimba
• Mukhale ndi zovuta komanso zopweteka m'mimba zomwe zimapitilira mwezi umodzi

Uzani wothandizira wanu za mankhwala omwe mumamwa. Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs) amathanso kuyambitsa zilonda. Ngati muwonetsa zizindikiro za matendawa, wothandizirayo atha kuyesa mayeso a H pylori. Izi zikuphatikiza:

• Mayeso a mpweya - urea kuyesa mpweya (Carbon Isotope-urea Breath Test, kapena UBT). Wopereka wanu amakupangitsani kumeza chinthu chapadera chomwe chili ndi urea. Ngati H pylori alipo, mabakiteriya amasintha urea kukhala mpweya woipa. Izi zimapezeka ndikulemba mu mpweya wanu pakatha mphindi 10.
• Kuyezetsa magazi - amayesa ma antibodies ku H pylori m'magazi anu.
• Kuyesa kopondapo - imazindikira kupezeka kwa mabakiteriya mu chopondapo.
• Chisokonezo - amayesa mtundu wazinyama womwe watengedwa kuchokera m'mimba mwa kugwiritsa ntchito endoscopy. Chitsanzocho chimayang'aniridwa ngati matenda a bakiteriya.

Kuti zilonda zanu zizichira komanso kuti muchepetse mwayi wobwerera, mudzapatsidwa mankhwala ku:

• Iphani H pylori mabakiteriya (ngati alipo)
• Kuchepetsa asidi m'mimba

Tengani mankhwala anu onse monga anauzidwira. Zosintha zina pamoyo zingathandizenso.

Ngati muli ndi zilonda zam'mimba ndi H pylori matenda, mankhwala akulimbikitsidwa. Mankhwalawa amaphatikizapo mankhwala osiyanasiyana kwa masiku 10 mpaka 14:

• Maantibayotiki opha H pylori
• Proton pump inhibitors kuthandiza kuchepetsa asidi m'mimba
• Bismuth (chinthu chachikulu mu Pepto-Bismol) chitha kuwonjezedwa kuti chithandizire kupha mabakiteriya

Kumwa mankhwala onsewa kwa masiku 14 sikuvuta. Koma kuchita izi kumakupatsani mwayi wabwino kwambiri wothandizira H pylori mabakiteriya komanso kupewa zilonda mtsogolo.

Ngati mumamwa mankhwala anu, pali mwayi waukulu kuti H pylori matenda adzachiritsidwa. Simudzakhala ndi chilonda china.

Nthawi zina, H pylori Zingakhale zovuta kuchiza kwathunthu. Njira zobwerezabwereza zamankhwala osiyanasiyana zimafunika. Nthawi zina amatenga m'mimba kuti ayese majeremusi kuti awone mankhwala omwe angagwire bwino ntchito. Izi zitha kuthandiza kuwongolera chithandizo chamtsogolo. Nthawi zina, H pylori sangachiritsidwe ndi mankhwala aliwonse, ngakhale zizindikilozo zitha kuchepetsedwa.

Ngati atachiritsidwa, kukonzanso kumatha kupezeka m'malo omwe ukhondo wake siwowoneka bwino.

Matenda a nthawi yayitali ( H pylori zingayambitse:

• Matenda a zilonda zam'mimba
• Kutupa kosatha
• Zilonda zam'mimba ndi kumtunda
• Khansa yam'mimba
• Matumbo am'mimba am'magazi amtundu wa lymphoid (MALT) lymphoma

Zovuta zina zingaphatikizepo:

• Kutaya magazi kwambiri
• Kupunduka kwa zilonda zam'mimba kungapangitse kuti zikhale zovuta m'mimba kukhuthula
• Kuwonongeka kapena dzenje la m'mimba ndi matumbo

Zizindikiro zazikulu zomwe zimayamba mwadzidzidzi zitha kuwonetsa kutsekeka m'matumbo, kutuluka, kapena kukha mwazi, zonse zomwe ndizadzidzidzi. Zizindikiro zimaphatikizapo:

• Dikirani, wakuda, kapena chimbudzi chamagazi
• Kusanza kwambiri, komwe kungaphatikizepo magazi kapena chinthu chowoneka ngati malo a khofi (chizindikiro cha kutaya magazi kwambiri) kapena zonse zam'mimba (chizindikiro chamatumbo)
• Kupweteka kwambiri m'mimba, kusanza kapena wopanda kapena umboni wamagazi

Aliyense amene ali ndi zizindikirozi ayenera kupita kuchipinda chadzidzidzi nthawi yomweyo.

H pylori matenda

• Mimba
• Esophagogastroduodenoscopy (EGD)
• Ma antibodies
• Malo azilonda zam'mimba

Phimbani TL, Blaser MJ. Helicobacter pylori ndi mitundu ina yam'mimba ya Helicobacter Mu: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, ndi Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 217.

Ku GY, Ilson DH. Khansa ya m'mimba. Mu: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, olemba. Chipatala cha Abeloff's Oncology. Lachisanu ndi chimodzi. Philadelphia, PA: Elsevier; 2020: chap 72.

Morgan DR, Crowe SE. Matenda a Helicobacter pylori. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Matenda a Mimba ndi a Fordtran Amatenda a Chiwindi. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 51.