Erlotinib

Zamkati

• Musanatenge erlotinib,
• Erlotinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo:

Erlotinib amagwiritsidwa ntchito pochiza mitundu ina ya khansa ya m'mapapo yomwe siying'ono yomwe yafalikira kumatenda oyandikana nawo kapena mbali zina za thupi mwa odwala omwe adalandira kale mankhwala amodzi amtundu wa chemotherapy ndipo sanakhale bwino. Erlotinib imagwiritsidwanso ntchito limodzi ndi mankhwala ena (gemcitabine [Gemzar]) kuchiza khansa ya kapamba yomwe yafalikira kumatenda oyandikira kapena mbali zina za thupi ndipo sangathe kuchiritsidwa ndi opaleshoni. Erlotinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Erlotinib amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa m'mimba yopanda kanthu kamodzi patsiku, osachepera ola limodzi isanakwane kapena maola awiri mutadya chakudya kapena chotupitsa. Tengani erlotinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani erlotinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu akhoza kuchepetsa mlingo wanu wa erlotinib mukamamwa mankhwala. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zomwe mumakumana nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Pitirizani kutenga erlotinib ngakhale mukumva bwino. Osasiya kumwa erlotinib osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge erlotinib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la erlotinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a erlotinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: angiogenesis inhibitors monga bevacizumab (Avastin); anticoagulants ('magazi ochepetsa magazi') monga warfarin (Coumadin); antifungals ena monga itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), ndi voriconazole (Vfend); boceprevir (Wopambana); carbamazepine (Tegretol); ciprofloxacin (Cipro, Proquin XR); clarithromycin (Biaxin); conivaptan (Vaprisol); HIV protease inhibitors monga atazanavir (Reyataz), indinavir (Crixivan), lopinavir / ritonavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir), ndi saquinavir (Fortovase, Invirase); H₂ zotchinga monga cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ndi ranitidine (Zantac); mankhwala aziphuphu monga benzoyl peroxide (ku Epiduo, ku BenzaClin, ku Benzamycin, ena); midazolam (Ndime): nefazodone; mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); mankhwala amlomo monga dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ndi prednisone (Deltasone); phenobarbital (Luminal, Solfoton); phenytoin (Dilantin); proton pump inhibitors monga esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), ndi rabeprazole (AcipHex); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); rifapentine; mankhwala amisonkho a khansa monga docetaxel (Taxotere) ndi paclitaxel (Abraxane, Taxol); telithromycin (Ketek); teriflunomide (Aubagio); ndi troleandomycin (TAO) (sikupezeka ku U.S.). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi erlotinib, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• ngati mukumwa maantacid, tengani maola angapo musanatenge erlotinib.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani adotolo ngati mukumuthandizirani kapena mwathandizidwa posachedwa ndi chemotherapy kapena radiation radiation (chithandizo cha khansa yomwe imagwiritsa ntchito mafunde amphamvu zamagetsi kupha ma cell a khansa). Uzani dokotala wanu ngati mwakhalapo ndi matenda am'mapapo kapena matenda, zilonda zam'mimba, matenda osokonekera (momwe matumba achilendo amapangidwira m'matumbo akulu ndipo amatha kutentha), kapena matenda a chiwindi kapena a impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukamamwa erlotinib komanso kwa mwezi umodzi mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito. Mukakhala ndi pakati, itanani dokotala wanu mwachangu. Erlotinib atha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa mankhwala ndi erlotinib komanso mpaka milungu iwiri mutatha kumwa mankhwala.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa erlotinib.
• uzani dokotala ngati mumagwiritsa ntchito fodya. Kusuta ndudu kumatha kuchepetsa mphamvu ya mankhwalawa.
• konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kuvala chipewa, zovala zina zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Sankhani zoteteza ku dzuwa zomwe zimakhala ndi zoteteza ku dzuwa (SPF) zosachepera 15 ndipo zimakhala ndi zinc oxide kapena titanium dioxide. Kuwonetsedwa ndi kuwala kwa dzuwa kumawonjezera chiopsezo kuti mutha kukhala ndi zotupa mukamamwa mankhwala ndi erlotinib.
• muyenera kudziwa kuti erlotinib imatha kuyambitsa ziphuphu komanso mavuto ena pakhungu. Kuti muteteze khungu lanu, gwiritsani ntchito mafuta osakaniza osamwa mowa, kutsuka khungu lanu ndi sopo wofatsa, ndikuchotsani zodzoladzola ndi zotsukira pang'ono.

Pewani kudya zipatso zamphesa ndikumwa madzi amphesa mukamamwa mankhwalawa.

Pofuna kupewa matenda otsekula m'mimba omwe angayambitsidwe ndi erlotinib, imwani timadzi tating'onoting'ono monga chakumwa chamasewera chopanda shuga nthawi zambiri tsiku lonse, idyani zakudya zofewa monga tchipisi ndi toast, komanso kupewa zakudya zokometsera.

Tengani mlingo wotsatira nthawi yanu tsiku lotsatira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Erlotinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• kusowa chilakolako
• nseru
• kusanza
• kutentha pa chifuwa
• mpweya
• kudzimbidwa
• zilonda mkamwa
• kuonda
• kutopa kwambiri
• mutu
• kupweteka kwa mafupa kapena minofu
• kukhumudwa
• nkhawa
• dzanzi, kutentha, kapena kumva kulira kwa manja kapena mapazi
• kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• khungu lakuda
• kutayika tsitsi
• kusintha kwa mawonekedwe a tsitsi ndi misomali

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• zidzolo (zitha kuwoneka ngati ziphuphu ndipo zimatha kukhudza khungu pamaso, pachifuwa chapamwamba, kapena kumbuyo)
• khungu, khungu, louma, kapena losweka
• kuyabwa, kukoma, kapena kutentha kwa khungu
• kupuma movutikira
• chifuwa
• malungo kapena kuzizira
• kukula kwa nsidze mkati mwa chikope
• kupweteka kwambiri m'mimba
• owuma, ofiira, opweteka, otulutsa misozi, kapena opunduka
• kusawona bwino
• kuzindikira kwa diso kuwala
• kupweteka pachifuwa kapena kupanikizika
• kupweteka kwa mikono, khosi, kapena kumtunda kwakumbuyo
• kugunda kwamtima msanga, kosasinthasintha, kapena kwamphamvu
• mawu odekha kapena ovuta
• chizungulire kapena kukomoka
• kufooka kapena kufooka kwa mkono kapena mwendo
• kuvulaza kapena kutuluka mwachilendo
• wakuda ndi wodikira kapena chimbudzi chamagazi
• masanzi omwe ali magazi kapena amaoneka ngati malo a khofi
• maso olowa
• pakamwa pouma
• kuchepa pokodza
• mkodzo wakuda
• khungu lotumbululuka kapena lachikaso
• kufiira, kutentha, kupweteka, kukoma mtima, kapena kutupa mwendo umodzi

Erlotinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kutsegula m'mimba
• zidzolo

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira erlotinib.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Tarceva^®