Dalfampridine
Zamkati
- Asanatenge dalfampridine,
- Dalfampridine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala wanu kapena pitani kuchipatala mwachangu:
- Zizindikiro za bongo zingaphatikizepo izi:
Dalfampridine imagwiritsidwa ntchito kukonza kuyenda kwa anthu omwe ali ndi multiple sclerosis (MS; matenda omwe misempha sagwira ntchito moyenera ndipo imatha kuyambitsa kufooka, kufooka, kutayika kwa kulumikizana kwa minofu, komanso mavuto a masomphenya, malankhulidwe, ndi chikhodzodzo). Dalfampridine itha kugwiritsidwa ntchito payokha kapena ndi mankhwala ena omwe amayang'anira zizindikiro za MS. Dalfampridine ali mgulu la mankhwala otchedwa potassium channel blockers. Zimagwira ntchito polimbitsa mphamvu zomwe zimatumizidwa ndi ubongo kudzera m'mitsempha yomwe yawonongeka ndi MS.
Dalfampridine amabwera ngati piritsi lotulutsira kuti atenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kawiri patsiku. Ikani magawo anu kuti mutenge mlingo umodzi pafupifupi maola 12 aliwonse, ndi kumwa dalfampridine mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani dalfampridine ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.
Kumeza mapiritsi lonse; osagawanika, kutafuna, kusungunula, kapena kuwaphwanya.
Dalfampridine sikupezeka m'masitolo. Mutha kungopeza dalfampridine kudzera pamakalata kuchokera kuma pharmacy apadera. Funsani dokotala wanu ngati muli ndi mafunso okhudza kulandira mankhwala anu.
Dalfampridine itha kuthandizira kukonza mayendedwe anu bola mukapitiliza kuwatenga. Zitha kutenga milungu isanu ndi umodzi kapena kupitilira apo musanapindule ndi dalfampridine. Pitirizani kumwa dalfampridine ngakhale mukumva bwino. Osasiya kumwa dalfampridine osalankhula ndi dokotala.
Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba mankhwala ndi dalfampridine ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti mupeze Chithandizo cha Mankhwala.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Asanatenge dalfampridine,
- auzeni adotolo ndi asayansi yanu ngati muli ndi vuto losagwirizana ndi dalfampridine, 4-aminopyridine (4-AP, fampridine) yomwe idakonzedwa ndi wamankhwala wanu, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a dalfampridine. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
- Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulanso mtundu wina uliwonse wa 4-aminopyridine (4-AP, fampridine) yomwe yakonzedwa ndi wazamankhwala wanu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
- auzeni adotolo ngati munadwalako kapena ngati mukudwala matenda a impso. Dokotala wanu angakuuzeni kuti musamwe dalfampridine.
- uzani dokotala ngati mwakhalapo ndi electroencephalogram (EEG, mayeso omwe amayesa magetsi muubongo).
- uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga dalfampridine, itanani dokotala wanu.
Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.
Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge dalfampridine wopitilira awiri mu nthawi yamaola 24 ndipo musamwe mlingo umodzi kuti ukhale wosowa.
Dalfampridine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- kuvuta kugona kapena kugona
- chizungulire
- mutu
- nseru
- kutentha pa chifuwa
- kudzimbidwa
- kufooka
- kupweteka kwa msana
- zovuta ndi kusamala
- Kukula kwa zizindikilo zingapo za sclerosis
- kutentha, kumva kulasalasa, kapena kuyabwa pakhungu
- kupweteka kapena kuyabwa pamphuno kapena pakhosi
Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala wanu kapena pitani kuchipatala mwachangu:
- kugwidwa
- kupweteka kovuta, kovuta, kapena pafupipafupi
- malungo kapena kuzizira
- kupweteka kumbuyo, mbali, kapena m'mimba
Dalfampridine ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).
Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.
Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Zizindikiro za bongo zingaphatikizepo izi:
- chisokonezo
- kugwidwa
- kugwedezeka kosalamulirika kwa gawo lina la thupi lanu
- thukuta
- kuiwalika
- mavuto olankhula
- kufooka
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzayitanitsa mayeso ena a labu kuti awone kuyankha kwa thupi lanu ku dalfampridine.
Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
- Ampyra®
- 4-aminopyridine
- 4-AP
- nthanga