Jekeseni wa Siltuximab

Zamkati

• Asanalandire jakisoni wa siltuximab,
• Jekeseni wa Siltuximab ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zili mgulu la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

Jekeseni wa Siltuximab umagwiritsidwa ntchito pochiza matenda amtundu wa Castleman (MCD; kuchuluka kwama cell am'magazi m'malo opitilira gawo limodzi la thupi omwe angayambitse zizindikilo ndipo atha kubweretsa chiopsezo chotenga matenda kapena khansa) mwa anthu omwe alibe kufooka kwa thupi kachilombo (HIV) ndi kachilombo ka herpesvirus-8 (HHV-8). Siltuximab ali mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito poletsa kuchitapo kanthu kwachilengedwe komwe kumayambitsa kukula kwa ma lymph maselo mwa anthu omwe ali ndi MCD.

Jekeseni wa Siltuximab umabwera ngati madzi oti alandire jakisoni (mumtsempha) kupitirira ola limodzi ndi wothandizira zaumoyo kuchipatala kapena kuofesi yazachipatala. Nthawi zambiri amaperekedwa kamodzi pamasabata atatu.

Mutha kuyankha mukalandira jakisoni wa siltuximab. Ngati mungayankhe, wothandizira zaumoyo wanu adzakuletsani kulowetsedwa kwanu ndipo adzakupatsani mankhwala kuti muchiritse zomwe mungachite. Ngati zomwe mukuchita zili zovuta, wothandizira zaumoyo wanu sangakupatseni infusions ya siltuximab. Uzani wothandizira zaumoyo wanu kapena mulandire chithandizo chamankhwala mwadzidzidzi mukakumana ndi izi: kufinya pachifuwa; kupuma; chizungulire kapena kupepuka; kutupa kwa nkhope, milomo, lilime kapena mmero; zidzolo; kuyabwa; mutu; kupweteka kwammbuyo; kupweteka pachifuwa; nseru; kusanza; kuthamanga; khungu lofiira; kapena kugunda kwa mtima.

Jekeseni wa Siltuximab itha kuthandizira kuwongolera MCD koma siyichiritsa. Pitirizani kusunga nthawi kuti mulandire jakisoni wa siltuximab ngakhale mukumva bwino.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa siltuximab,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi jakisoni wa siltuximab, mankhwala ena aliwonse, kapena zina zilizonse zopangira jakisoni wa siltuximab. Funsani wamankhwala wanu kapena onani zomwe wodwala akupanga kuti muwone mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: anticoagulants ('magazi ochepetsa magazi') monga warfarin (Coumadin, Jantoven), atorvastatin (Lipitor), cyclosporine (Gengraf, Neoral, Sandimmune), lovastatin (ku Altoprev), njira zakulera zakumwa. mapiritsi), ndi theophylline (Theo-24, Uniphyl). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati muli ndi matenda aliwonse musanayambe mankhwala anu ndi jakisoni wa siltuximab, kapena ngati muwona zizindikiro zilizonse za matenda mukamalandira. Uzani dokotala wanu ngati mwakhalapo ndi vuto lililonse lomwe limakhudza m'mimba kapena m'matumbo monga zilonda zam'mimba (zilonda zamkati mwa m'mimba kapena m'matumbo) kapena diverticulitis (timatumba tating'onoting'ono tomwe timatupa).
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamamwa jakisoni wa siltuximab komanso kwa miyezi itatu mutalandira chithandizo. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukalandira jakisoni wa siltuximab, itanani dokotala wanu mwachangu. Siltuximab ikhoza kuvulaza mwana wosabadwayo.
• mulibe katemera popanda kulankhula ndi dokotala. Uzaninso dokotala wanu ngati mwalandira katemera posachedwa. Lankhulani ndi dokotala wanu ngati mungalandire katemera musanayambe kumwa mankhwala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya nthawi kuti mulandire jakisoni wa siltuximab, itanani dokotala wanu posachedwa.

Jekeseni wa Siltuximab ingayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mdima wa khungu
• khungu lowuma
• kudzimbidwa
• kupweteka pakamwa kapena pakhosi
• kunenepa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zili mgulu la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• malungo, zilonda zapakhosi, kuzizira, kapena zizindikiro zina za matenda
• kuvulaza kapena kutuluka mwachilendo
• kutupa kwa manja, mikono, mapazi, akakolo, kapena miyendo yakumunsi

Jekeseni wa Siltuximab ingayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira jakisoni wa siltuximab.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza jekeseni wa siltuximab.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Sylvant^®