Jekeseni wa Buprenorphine

Zamkati

• Asanalandire jakisoni wa buprenorphine,
• Jekeseni womasulira wa Buprenorphine amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Jekeseni womasulira wa Buprenorphine umapezeka pokhapokha kudzera mu pulogalamu yapadera yogawa yotchedwa Sublocade REMS. Dokotala wanu ndi pharmacy wanu ayenera kulembetsa nawo pulogalamuyi musanalandire jakisoni wa buprenorphine. Funsani dokotala wanu kuti mumve zambiri za pulogalamuyi komanso momwe mungalandire mankhwala anu.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu lingayankhire jakisoni wotulutsa buprenorphine.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wokulutsani wa buprenorphine ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti mupeze Chithandizo cha Mankhwala.

Jekeseni womasulira wa Buprenorphine amagwiritsidwa ntchito pochiza kudalira kwa opioid (mankhwala osokoneza bongo a opioid, kuphatikiza ma heroin ndi mankhwala opha ululu) mwa anthu omwe alandila buccal kapena buprenorphine ya masiku ochepa kwa masiku osachepera 7. Jekeseni womasulira wa Buprenorphine ali mgulu la mankhwala otchedwa opiate pang'ono agonists. Zimagwira ntchito popewa zizindikiritso zakudzitchinjiriza munthu wina atasiya kumwa mankhwala opioid popanga zomwezo ndi mankhwalawa.

Jekeseni wa Buprenorphine wotulutsa (wotenga nthawi yayitali) umabwera ngati yankho (madzi) kuti alandire jakisoni (pansi pa khungu) ndi wothandizira zaumoyo m'mimba. Kawirikawiri amaperekedwa kamodzi pamwezi ndi masiku osachepera 26 pakati pa mlingo. Jakisoni aliyense wa buprenorphine amatulutsa pang'onopang'ono mankhwalawa mthupi lanu kupitirira mwezi.

Mukalandira jakisoni wotulutsa buprenorphine, mutha kuwona chotupa pamalo obayira kwa milungu ingapo, koma chiyenera kuchepa pakapita nthawi. Osapaka kapena kusisita malo obayira jekeseni. Onetsetsani kuti lamba wanu kapena lamba wanu samakakamiza pomwe munabayidwa mankhwala.

Dokotala wanu akhoza kukulitsa kapena kuchepetsa mlingo wanu kutengera momwe mankhwalawo amakuthandizirani, komanso zovuta zina zomwe mumakumana nazo. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha jekeseni womasulira wa buprenorphine.

Ngati buprenorphine yotulutsidwa ikumasulidwa, dokotala wanu amachepetsa mlingo wanu pang'onopang'ono. Mutha kukhala ndi zisonyezo zakubwerera m'mbuyo kuphatikizapo kusapuma, maso akuthira thukuta, kuzizira, kukulira kwa ana (mabwalo akuda pakati pa maso), kukwiya, nkhawa, kupweteka kwa msana, kufooka, kukokana m'mimba, kuvuta kugona kapena kugona, nseru, kusowa kwa njala, kusanza, kutsegula m'mimba, kupuma msanga, kapena kugunda kwamtima. Zizindikiro zakubwezeretsaku zitha kuchitika mwezi umodzi kapena kupitilira apo mukamamwa jekeseni womaliza wa buprenorphine.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa buprenorphine,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la buprenorphine, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu jakisoni wa buprenorphine. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: antihistamines; benzodiazepines monga alprazolam (Xanax), chlordiazepoxide (Librium, ku Librax), clonazepam (Klonopin), diazepam (Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), triazolion) carbamazepine (Carbatrol, Tegretol, Teril, ena); okodzetsa ('mapiritsi amadzi'); erythromycin (EES, Eryc, PCE, ena); Mankhwala a HIV monga atazanavir (Reyataz, ku Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, ku Atripla), etravirine (Intelence), indinavir (Crixivan), nevirapine (Viramune), ritonavir (Norvir, ku Kaletra), ndi saquinav (Invirase); mankhwala ena osagunda pamtima kuphatikiza amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid), quinidine (ku Nuedexta), ndi sotalol (Betapace, Betapace AF, Sorine); mankhwala a glaucoma, matenda amisala, kuyenda koyenda, matenda a Parkinson, zilonda zam'mimba, kapena mavuto amikodzo; ketoconazole, mankhwala ena opweteka; mankhwala a mutu waching'alang'ala monga almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, ku Treximet), ndi zolmitriptan (Zomig); zotsegula minofu; phenobarbital; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane); mankhwala ogonetsa; mapiritsi ogona; 5HT3 serotonin blockers monga alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), kapena palonosetron (Aloxi); serotonin-reuptake inhibitors monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, mu Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), ndi sertraline (Zoloft); serotonin ndi norepinephrine reuptake inhibitors monga duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Savella), ndi venlafaxine (Effexor); tramadol; zotetezera; trazodone; kapena tricyclic antidepressants ('mood elevator') monga amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactiline), ndi trimipramine. Komanso uzani dokotala wanu kapena wamankhwala ngati mukumwa kapena kulandira mankhwala otsatirawa a monoamine oxidase (MAO) kapena ngati mwasiya kuwamwa m'masabata awiri apitawa: isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil) , selegiline (Eldepryl, Emsam, Zelapar), kapena tranylcypromine (Parnate). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi buprenorphine, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• auzeni adotolo ngati inu kapena wachibale wanu mumamwa kapena mwakhala mukumwapo mowa wambiri kapena mwakhala mukukhala ndi matenda a QT kwa nthawi yayitali (zomwe zimawonjezera chiopsezo chokhala ndi kugunda kwamtima kosasunthika komwe kumatha kutayika kapena kufa mwadzidzidzi). Komanso, uzani dokotala ngati mwakhalapo ndi potaziyamu kapena magnesium wambiri m'magazi; mtima kulephera; kugunda pang'onopang'ono kapena kosasinthasintha; Matenda osokoneza bongo (COPD; gulu la matenda omwe amakhudza mapapu ndi njira zowuluka); matenda ena am'mapapo; kuvulala pamutu; chotupa muubongo; vuto lililonse lomwe limakulitsa kuchuluka kwa zovuta muubongo wanu; mavuto a adrenal monga matenda a Addison (momwe adrenal gland imatulutsira mahomoni ocheperako kuposa zachilendo); benign prostatic hypertrophy (BPH, kukulitsa kwa prostate gland); zovuta kukodza; kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe); kupindika kwa msana komwe kumapangitsa kupuma kupuma; kapena chithokomiro, ndulu, kapena matenda a chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Ngati mumalandira jakisoni wotulutsa buprenorphine pafupipafupi mukakhala ndi pakati, mwana wanu amatha kukhala ndi ziwopsezo zochoka pobereka. Uzani dokotala wa mwana wanu nthawi yomweyo ngati mwana wanu akukumana ndi izi: kukwiya, kusakhazikika, kugona mokwanira, kulira kwambiri, kugwedeza kosalamulirika kwa gawo lina la thupi, kusanza, kutsegula m'mimba, kapena kulephera kunenepa.
• Uzani dokotala wanu ngati mukuyamwitsa. Uzani dokotala wa mwana wanu nthawi yomweyo ngati mwana wanu wagona tulo kuposa masiku onse kapena amavutika kupuma mukalandira mankhwalawa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito jakisoni wotulutsa buprenorphine.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukulandira jakisoni wotulutsa buprenorphine.
• muyenera kudziwa kuti jakisoni wotulutsa buprenorphine atha kukupangitsani kugona. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• simuyenera kumwa mowa kapena kugwiritsa ntchito mankhwala osokoneza bongo mumsewu mukamamwa mankhwala. Kumwa mowa, kumwa mankhwala akuchipatala kapena osapereka mankhwala omwe ali ndi mowa, kapena kugwiritsa ntchito mankhwala osokoneza bongo mukamamwa mankhwala a jekeseni wa buprenorphine kumawonjezera chiopsezo choti mudzakumana ndi mavuto akulu komanso owopsa moyo.
• muyenera kudziwa kuti buprenorphine imatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukaimirira mwachangu pamalo abodza. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.
• Muyenera kudziwa kuti buprenorphine imatha kudzimbidwa. Lankhulani ndi dokotala wanu zakusintha kadyedwe kanu kapena kugwiritsa ntchito mankhwala ena kuti muchepetse kapena kudzimbidwa mukamagwiritsa ntchito jakisoni wa buprenorphine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya jekeseni womasulidwa wa buprenorphine, muyenera kuyimbira dokotala kuti akalandire mankhwalawo posachedwa. Mlingo wanu wotsatira uyenera kuperekedwa patatha masiku 26.

Jekeseni womasulira wa Buprenorphine amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• mutu
• kutopa
• ululu, kuyabwa, kutupa, kusapeza bwino, kufiyira, mabala, kapena zopunthira pamalo obayira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• kuvuta kupuma
• kusakhazikika, kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe), malungo, thukuta, chisokonezo, kugunda kwa mtima, kunjenjemera, kuyankhula modekha, kuuma kwambiri kwa minofu kapena kugwedezeka, kutayika kwa mgwirizano, nseru, kusanza, kapena kutsekula m'mimba
• nseru, kusanza, kusowa kwa njala, kufooka, kapena chizungulire
• Kulephera kupeza kapena kusunga erection
• msambo wosasamba
• Kuchepetsa chilakolako chogonana
• zidzolo
• ming'oma
• kuyabwa
• mawu osalankhula
• kusawona bwino
• kusintha kwa kugunda kwa mtima
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• mkodzo wamtundu wakuda
• mipando yoyera

Jekeseni womasulira wa Buprenorphine atha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Imbani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kuchepa kapena kukulira kwa ana (mabwalo akuda pakati pa diso)
• Kuchepetsa kapena kupuma movutikira
• kugona kwambiri kapena kugona
• chikomokere (kutaya chidziwitso kwakanthawi)
• kugunda kochedwa mtima

Musanayezetsedwe kwa labotale (makamaka yomwe imakhudza methylene buluu), uzani adotolo ndi ogwira nawo ntchito kuti mukugwiritsa ntchito jakisoni wa buprenorphine.

Pankhani yadzidzidzi, wachibale kapena wowasamalira ayenera kuuza azachipatala kuti mumadalira opioid ndipo mukulandira jekeseni womasulira wa buprenorphine.

Buprenorphine jekeseni womasula ndi chinthu chowongoleredwa. Onetsetsani kuti mwakhazikitsa nthawi yokumana ndi dokotala wanu kuti mulandire jakisoni wanu. Funsani wamankhwala wanu ngati muli ndi mafunso.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zosintha^®