Mlembi: Gregory Harris
Tsiku La Chilengedwe: 15 Epulo 2021
Sinthani Tsiku: 27 Okotobala 2024
Anonim
Tafenoquine: Malaria Drug Development
Kanema: Tafenoquine: Malaria Drug Development

Zamkati

Tafenoquine (Krintafel) amagwiritsidwa ntchito popewa kubwereranso kwa malungo (matenda opatsirana omwe amafalitsidwa ndi udzudzu m'malo ena padziko lapansi ndipo amatha kupha) mwa anthu azaka 16 kapena kupitilira apo omwe ali ndi kachilomboka ndipo pakadali pano alandila chloroquine kapena hydroxychloroquine kuchiza malungo. Tafenoquine (Arakoda) imagwiritsidwa ntchito paokha popewa malungo kwa apaulendo omwe amayendera madera omwe malungo amapezeka. Tafenoquine ali mgulu la mankhwala otchedwa antimalarials. Zimagwira ntchito popha zamoyo zomwe zimayambitsa malungo.

Tafenoquine imabwera ngati mapiritsi oti azimwa pakamwa ndi chakudya. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani tafenoquine ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukumwa tafenoquine (Krintafel) kuti muteteze malungo kuti asabwerere, nthawi zambiri amatengedwa ngati muyezo umodzi (mapiritsi awiri) patsiku loyamba kapena lachiwiri la mankhwala anu ndi chloroquine kapena hydroxychloroquine.


Ngati mukumwa tafenoquine (Arakoda) popewa malungo, mankhwala amodzi (mapiritsi awiri) amatengedwa kamodzi patsiku kwa masiku atatu, kuyambira masiku atatu musanapite kudera komwe kuli malungo. Mukakhala m'derali, mlingo umodzi (mapiritsi awiri) amatengedwa kamodzi pa sabata tsiku lomwelo la sabata. Mukabwerera kuchokera kumaloko, mankhwala amodzi (mapiritsi awiri) amatengedwa masiku asanu ndi awiri mutangomaliza kumwa mankhwala musanabwerere. Simuyenera kumwa tafenoquine (Arakoda) popewa malungo kwa miyezi yopitilira 6.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Mukasanza pasanathe ola limodzi mutatenga tafenoquine (Krintafel), itanani dokotala wanu. Mungafunike kumwa mankhwala ena.

Tengani tafenoquine mpaka mutha kumaliza mankhwala, ngakhale mutakhala bwino. Mukasiya kumwa tafenoquine posachedwa kapena kudumpha mlingo, matenda anu sangachiritsidwe kwathunthu kapena simungatetezedwe ku matenda amtsogolo.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zambiri za wopanga ngati mukumwa Tafenoquine (Krintafel). Ngati mukumwa tafenoquine (Arakoda), dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso zaopanga (Medication Guide) mukayamba chithandizo komanso nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti mupeze Chithandizo cha Mankhwala.


Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge tafenoquine,

  • uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la tafenoquine, primaquine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a tafenoquine.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: dofetilide (Tikosyn) ndi metformin (Fortamet, Glucophage, Riomet, ku Actoplus Met, ena). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala ngati muli ndi vuto la glucose-6-phosphate dehydrogenase (G-6-PD) (matenda obadwa nawo m'magazi). Dokotala wanu angakuuzeni kuti musatenge tafenoquine. Muuzeni dokotala ngati mwakhalapo ndi matenda amisala kapena simunakhalepo ndi matenda amisala. Dokotala wanu akhoza kukuwuzani kuti musatenge tafenoquine.
  • auzeni adotolo ngati mudakhalako kapena munakhalapo ndi hemolytic anemia (matenda omwe ali ndi magazi ofiira ochepa), methemoglobinemia (vuto lokhala ndi ma cell ofiira ofiira omwe sangathe kunyamula mpweya kumatumbo), nicotinamide kusowa kwa adenine dinucleotide (NADH) (chibadwa), kapena matenda a impso kapena chiwindi.
  • Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Ngati ndinu mayi wazaka zobereka, muyenera kuyezetsa asanayambe kulandira mankhwala. Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamamwa mankhwala a tafenoquine komanso kwa miyezi itatu mutalandira mankhwala. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukatenga tafenoquine, itanani dokotala wanu mwachangu. Tafenoquine itha kuvulaza mwana wosabadwayo.
  • auzeni dokotala ngati mukuyamwitsa kapena mukufuna kuyamwitsa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Itanani dokotala wanu kapena wamankhwala kuti akufunseni zoyenera kuchita ngati mwaphonya mlingo wa tafenoquine (Arakoda).

Tafenoquine imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • nseru
  • kusanza
  • kutsegula m'mimba
  • kuvuta kugona kapena kugona
  • nkhawa
  • amasintha malingaliro
  • maloto achilendo
  • mutu
  • mavuto owonera, kuphatikiza kusawona bwino kapena kuzindikira kuwala

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

  • zidzolo
  • ming'oma
  • kutupa kwa maso, nkhope, milomo, lilime, pakamwa, kapena pakhosi
  • kuvuta kupuma kapena kumeza
  • kupuma movutikira
  • hoarseness kapena pakhosi pothina
  • mkodzo wachikuda
  • mtundu wa milomo yaimvi ndi / kapena khungu
  • chizungulire
  • chisokonezo
  • kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
  • zonyenga (kukhala ndi malingaliro kapena zikhulupiriro zachilendo zomwe zilibe maziko) monga malingaliro omwe anthu akufuna kukuvulazani ngakhale sangatero
  • wamisala
  • chikasu cha khungu kapena maso

Tafenoquine imatha kubweretsa zovuta zina.Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku tafenoquine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Arakoda®
  • Krintafel®
Idasinthidwa Komaliza - 02/15/2021

Zolemba Zatsopano

Adalgur N - Thandizo Lopumulira Minyewa

Adalgur N - Thandizo Lopumulira Minyewa

Adalgur N ndi mankhwala omwe amawonet edwa kuti azitha kupweteka pang'ono, monga cholumikizira pochiza kupweteka kwa minofu kapena munthawi zovuta zokhudzana ndi m ana. Izi mankhwala ali kapangidw...
Njira Zapamwamba Zotetezera Panyumba Mimba

Njira Zapamwamba Zotetezera Panyumba Mimba

Zithandizo zapakhomo zothet a chifuwa panthawi yoyembekezera zimathandiza kuthet a mavuto, ndikupangit a kuti mayi akhale ndi moyo wabwino. Chifukwa chake, atha kulimbikit idwa ndi adotolo kuti adye a...