Selinexor

Zamkati

• Musanatenge selinexor,
• Selinexor angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Selinexor imagwiritsidwa ntchito limodzi ndi dexamethasone kuchiza ma myeloma angapo (mtundu wa khansa ya m'mafupa) yomwe yabwerera kapena yomwe sinayankhe mankhwala ena osachepera 4. Selinexor imagwiritsidwanso ntchito ndi bortezomib ndi dexamethasone pochiza matenda angapo a myeloma kwa odwala omwe adalandirapo mankhwala osachepera amodzi. Amagwiritsidwanso ntchito kuthana ndi mitundu ina yayikulu ya B-cell lymphoma (DLBCL; mtundu wa khansa womwe umayambira m'maselo oyera a magazi) mwa achikulire omwe khansa yabwerera kapena yosamvera mankhwala ena awiri. Selinexor ali mgulu la mankhwala otchedwa selective inhibitors of export export (SINE). Zimagwira ntchito popha ma cell a khansa.

Selinexor amabwera ngati piritsi kuti adye pakamwa kapena wopanda chakudya. Kuti mugwiritse ntchito limodzi ndi dexamethasone pochiza ma myeloma angapo kapena pochiza DLBCL, selinexor nthawi zambiri amatengedwa masiku 1 ndi 3 sabata iliyonse. Pofuna kugwiritsidwa ntchito limodzi ndi bortezomib ndi dexamethasone pochiza ma myeloma angapo, selinexor nthawi zambiri amatengedwa kamodzi pa sabata. Tengani selinexor mozungulira nthawi yofanana tsiku lililonse tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani selinexor ndendende monga mwalamulira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi athunthu ndi madzi; osagawana, kutafuna, kapena kuwaphwanya.

Ngati musanza mutamwa selinexor, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kukuwuzani kuti mumwe mankhwala kuti muchepetse mseru komanso kusanza musanamwe mankhwala komanso selinexor.

Dokotala wanu angafunikire kuyimitsa kapena kusokoneza chithandizo chanu kapena kuchepetsa mlingo wanu ngati mukukumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira mankhwala a selinexor.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge selinexor,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la selinexor, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a selinexor. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhala mukudwala kapena mwangodwala kumene, ngati mwakhala mukudwala kapena muli ndi vuto la kutuluka magazi, kapena ngati muli ndi ng'ala (mitambo ya diso la diso).
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kukhala ndi mayeso olakwika okhudzana ndi mimba musanayambe kumwa selinexor. Ngati ndinu wamkazi, simuyenera kutenga pakati mukamamwa selinexor komanso mpaka sabata limodzi mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo ndikupitiliza kugwiritsa ntchito njira yolerera kwa sabata limodzi mutatha kumwa. Ngati inu kapena mnzanu mumakhala ndi pakati mukumwa selinexor, itanani dokotala wanu mwachangu. Selinexor atha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa selinexor komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai.
• muyenera kudziwa kuti selinexor imatha kukupangitsani kugona kapena kuyambitsa chizungulire kapena kukomoka. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Dokotala wanu angakulimbikitseninso kuti muzimwa zakumwa zokwanira ndikudya zopatsa mphamvu zokwanira mukamalandira chithandizo.

Ngati mwaphonya mlingo, tulukani mlingowo ndipo imwani mankhwala anu tsiku ndi nthawi yanu yotsatira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Selinexor angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kudzimbidwa
• kuonda
• kusowa chilakolako
• kutopa kwambiri
• kuvuta kugona kapena kugona
• mutu
• kusintha kwa kukoma

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• Kutuluka magazi kapena kuvulala mosavuta
• kutopa, khungu lotuwa, kapena kupuma movutikira
• malungo, chifuwa, kuzizira, kapena zizindikiro zina za matenda
• kuwona zinthu kapena kumva mawu omwe kulibe
• chisokonezo
• kusawona bwino kapena masomphenya awiri
• kuchulukitsa chidwi cha kuwala ndi kunyezimira

Selinexor angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amayang'anira kulemera kwa thupi lanu ndikuitanitsa mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku selinexor.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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