Mlembi: Janice Evans
Tsiku La Chilengedwe: 2 Kulayi 2021
Sinthani Tsiku: 14 Novembala 2024
Anonim
Study of sacituzumab govitecan for triple-negative breast cancer
Kanema: Study of sacituzumab govitecan for triple-negative breast cancer

Zamkati

Sacituzumab govitecan-hziy ingayambitse kuchepa kwakukulu kwa kuchuluka kwa maselo oyera amwazi m'magazi anu. Dokotala wanu amalamula kuyesedwa kwa labotale nthawi zonse mukamalandira chithandizo kuti muwone kuchuluka kwa maselo oyera m'magazi anu. Kuchepa kwa maselo oyera m'magazi mwanu kumatha kuonjezera chiopsezo choti mungadwale kwambiri. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: malungo, kuzizira, zilonda zapakhosi, kupuma movutikira, kutsokomola kosalekeza komanso kuchulukana, kutentha kapena kupweteka mukakodza, kapena zizindikilo zina za matenda.

Sacituzumab govitecan-hziy imatha kuyambitsa kutsegula m'mimba kwambiri. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: zotchinga; kutsegula m'mimba; chimbudzi chakuda kapena chamagazi; zizindikiro za kuchepa kwa madzi m'thupi monga mutu wopepuka, chizungulire, kapena kukomoka; kapena ngati mukulephera kumwa madzi pakamwa chifukwa cha mseru kapena kusanza. Lankhulani ndi dokotala wanu zomwe muyenera kuchita ngati mukudwala matenda otsekula m'mimba nthawi iliyonse mukamalandira sacituzumab govitecan-hziy kapena ngati sangayilamulire pasanathe maola 24 mutalandira chithandizo chamankhwala otsekula m'mimba.


Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone kuyankha kwa thupi lanu ku sacituzumab govitecan-hziy.

Lankhulani ndi dokotala wanu za kuopsa kolandila sacituzumab govitecan-hziy.

Sacituzumab govitecan-hziy imagwiritsidwa ntchito pochiza khansa ya m'mawere mwa akulu yomwe yafalikira mbali zina za thupi ndipo yathandizidwa kale ndi mankhwala ena osachepera awiri a chemotherapy. Sacituzumab govitecan-hziy ili mgulu la mankhwala otchedwa anti-drug conjugates. Zimagwira ntchito popha ma cell a khansa.

Sacituzumab govitecan-hziy imabwera ngati ufa wothira madzi ndikubaya jakisoni (mumtsempha) kupitilira maola 1 mpaka 3 ndi dokotala kapena namwino kuchipatala kapena kuchipatala. Nthawi zambiri amaperekedwa masiku 1 ndi 8 a masiku 21. Kuzungulira kumatha kubwerezedwa monga momwe dokotala akuwalimbikitsira. Kutalika kwa chithandizo chanu kumadalira momwe thupi lanu limayankhira ndi mankhwala ndi zovuta zina zomwe mumakumana nazo.


Sacituzumab govitecan-hziy jakisoni imatha kuyambitsa nseru, kusanza, komanso kuyanjana kwambiri, komwe kumachitika nthawi yayitali ndikulowetsedwa kwamankhwala kapena mkati mwa maola 24 mulandila. Mupatsidwa mankhwala ena othandizira kupewa ndi kuchiza zomwe mungachite. Dokotala kapena namwino adzakuyang'anirani mosamala nthawi ndi mphindi 30 mutalowetsedwa pazomwe mungachite ndi mankhwalawa. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: nseru; kusanza; kutupa kwa nkhope yanu, milomo, lilime, kapena mmero; malungo; chizungulire; kuthamanga; kuzizira; zidzolo; ming'oma; kuyabwa; kupuma; kapena kupuma movutikira.

Dokotala wanu akhoza kuchepetsa mlingo wanu kapena kuimitsa kanthawi kochepa kapena kosatha. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zomwe mumakumana nazo. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo ndi sacituzumab govitecan-hziy.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.


Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire sacituzumab govitecan-hziy,

  • uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi sacituzumab govitecan-hziy, mankhwala ena aliwonse, kapena chilichonse mwazomwe zimaphatikizidwa mu jakisoni wa sacituzumab govitecan-hziy. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Equetro, Teril, ena), atazanavir (Reyataz, ku Evotaz), indinavir (Crixivan), irinotecan (Camptosar, Onivyde), phenobarbital, rifampin (Rifadin, ku Rifater, ndi sorafenib (Nexavar). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi.
  • uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena ngati mukufuna kukhala ndi mwana. Inu kapena mnzanu simuyenera kutenga pakati pomwe mukulandira jakisoni wa sacituzumab govitecan-hziy. Ngati ndinu mayi amene angathe kutenga pakati, muyenera kuyezetsa asanayambe kulandira chithandizo ndikugwiritsa ntchito njira yolerera panthawi yomwe mukumwa mankhwala komanso kwa miyezi 6 mutatha kumwa. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo komanso kwa miyezi itatu mutalandira mankhwala. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati inu kapena mnzanu mukhala ndi pakati mukalandira jakisoni wa sacituzumab govitecan-hziy, itanani dokotala wanu. Sacituzumab govitecan-hziy itha kuvulaza mwana wosabadwayo.
  • Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukalandira sacituzumab govitecan-hziy komanso kwa mwezi umodzi mutatha kumwa.
  • Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amayi. Lankhulani ndi dokotala wanu za kuopsa kolandila sacituzumab govitecan-hziy.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwaphonya nthawi yolandila sacituzumab govitecan-hziy, itanani dokotala wanu nthawi yomweyo.

Sacituzumab govitecan-hziy itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kudzimbidwa
  • zilonda mkamwa
  • kupweteka m'mimba
  • kutopa
  • kusowa chilakolako
  • kusintha kwa kukoma
  • kutayika tsitsi
  • khungu lowuma
  • mutu
  • kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
  • kupweteka kumbuyo kapena kumalumikizana
  • kupweteka kwa mikono kapena miyendo
  • kutupa kwa manja, akakolo, kapena mapazi
  • kuvuta kugona kapena kugona
  • khungu lotuwa kapena kutopa kwachilendo kapena kufooka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA NDI MALO, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala mwadzidzidzi:

  • kuvulaza kosavuta kapena kutuluka magazi; kutuluka magazi m'kamwa kapena m'mphuno; kapena magazi mkodzo kapena chopondapo

Sacituzumab govitecan-hziy itha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

  • malungo, kuzizira, chifuwa, kapena zizindikiro zina za matenda

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza sacituzumab govitecan-hziy. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu musanayambe mankhwala anu kuti muwone ngati mungakhale ndi chiopsezo chowonjezeka cha zotsatirapo za sacituzumab govitecan-hziy kutengera kubadwa kwanu kapena mapangidwe amtundu wanu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Zamgululi®
Idasinthidwa Komaliza - 06/15/2020

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