Mlembi: Gregory Harris
Tsiku La Chilengedwe: 9 Epulo 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
The Evidence for Chlorpromazine
Kanema: The Evidence for Chlorpromazine

Zamkati

Kafukufuku wasonyeza kuti achikulire omwe ali ndi vuto la misala (vuto laubongo lomwe limakhudza kukumbukira, kuganiza bwino, kulumikizana, ndikuchita zochitika za tsiku ndi tsiku zomwe zingayambitse kusintha kwa malingaliro ndi umunthu) omwe amatenga ma antipsychotic (mankhwala amisala) monga chlorpromazine khalani ndi mwayi wambiri wakufa panthawi yachithandizo.

Chlorpromazine sivomerezedwa ndi Food and Drug Administration (FDA) pochiza mavuto amachitidwe mwa achikulire omwe ali ndi matenda amisala. Lankhulani ndi dokotala yemwe wakupatsani mankhwalawa ngati inu, wachibale wanu, kapena wina aliyense amene mumamusamalira ali ndi matenda amisala ndipo akutenga chlorpromazine. Kuti mumve zambiri, pitani patsamba la FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm

Chlorpromazine imagwiritsidwa ntchito kuthana ndi matenda a schizophrenia (matenda amisala omwe amachititsa kusokonezeka kapena kuganiza kosazolowereka, kutaya chidwi m'moyo, komanso kukhudzika kapena zosayenera) ndi zovuta zina zama psychotic (zomwe zimayambitsa kuvuta kusiyanitsa pakati pa zinthu kapena malingaliro omwe ali zenizeni ndi zinthu kapena malingaliro omwe siali enieni) ndikuchiza matenda amanjenje (okwiya, okhumudwa modabwitsa) mwa anthu omwe ali ndi vuto losinthasintha zochitika (manic depression disorder; vuto lomwe limayambitsa magawo amanjenje, magawo okhumudwa, ndi zina zachilendo Maganizo). Chlorpromazine imagwiritsidwanso ntchito kuthana ndi zovuta zamakhalidwe monga kuphulika, nkhanza komanso kusakhudzidwa kwa ana azaka 1 mpaka 12 zakubadwa. Chlorpromazine imagwiritsidwanso ntchito kuthana ndi nseru ndi kusanza, kutulutsa ma hiccups omwe atha mwezi umodzi kapena kupitilira apo, komanso kuti athetse kupumula komanso mantha omwe angachitike atangotsala pang'ono kuchitidwa opaleshoni. Chlorpromazine imagwiritsidwanso ntchito pochizira porphyria yapakatikati (momwe zinthu zina zachilengedwe zimakhalira mthupi ndikupangitsa kupweteka m'mimba, kusintha kwamaganizidwe ndi machitidwe, ndi zizindikilo zina). Chlorpromazine imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuchiza kafumbata (matenda akulu omwe angayambitse minofu, makamaka nsagwada). Chlorpromazine ali mgulu la mankhwala otchedwa antipsychotic ochiritsira. Zimagwira ntchito posintha zochitika za zinthu zina zachilengedwe muubongo ndi ziwalo zina za thupi.


Chlorpromazine imabwera ngati piritsi kuti itenge pakamwa. Chlorpromazine nthawi zambiri amatengedwa kawiri kapena kanayi patsiku. Mankhwala a chlorpromazine akagwiritsidwa ntchito poletsa nseru ndi kusanza, nthawi zambiri amatengedwa maola 4-6 iliyonse pakufunika. Mankhwala a chlorpromazine akagwiritsidwa ntchito kuti athetse mantha asanafike opaleshoni, nthawi zambiri amatengedwa maola 2-3 asanachitike opareshoni. Mankhwala a chlorpromazine akagwiritsidwa ntchito kuthana ndi ma hiccups, nthawi zambiri amatengedwa katatu patsiku kwa masiku atatu kapena mpaka ma hiccups atayima. Ngati ma hiccups sasiya pambuyo pa masiku atatu akumwa, mankhwala ena ayenera kugwiritsidwa ntchito. Ngati mumamwa chlorpromazine nthawi zonse, imwani nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani chlorpromazine ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa chlorpromazine ndipo pang'onopang'ono muwonjezere mlingo wanu. Dokotala wanu amachepetsa mlingo wanu mukangoyang'aniridwa. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira mankhwala a chlorpromazine.


Ngati mukumwa mankhwala a chlorpromazine kuchiza schizophrenia kapena matenda ena amisala, chlorpromazine imatha kuwongolera zizindikilo zanu koma sizingathetse vuto lanu. Pitirizani kumwa chlorpromazine ngakhale mukumva bwino. Osasiya kumwa mankhwala a chlorpromazine osalankhula ndi dokotala. Dokotala wanu mwina amachepetsa mlingo wanu pang'onopang'ono. Mukasiya kumwa mankhwala a chlorpromazine mwadzidzidzi, mutha kukhala ndi zizindikilo zobwerera m'mbuyo, monga nseru, kusanza, kupweteka m'mimba, chizungulire, komanso kusakhazikika.

Mankhwalawa amatha kupatsidwa ntchito zina; lankhulani ndi dokotala kapena wamankhwala kuti mumve zambiri.

Musanayambe kumwa mankhwala a chlorpromazine,

  • Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la mankhwala a chlorpromazine; phenothiazines ena monga fluphenazine, perphenazine, prochlorperazine (Compazine), promethazine (Phenergan), thioridazine, ndi trifluoperazine; kapena mankhwala ena aliwonse.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants (ochepetsa magazi) monga warfarin (Coumadin); mankhwala opatsirana pogonana; mankhwala; atropine (ku Motofen, ku Lomotil, ku Lonox); barbiturates monga pentobarbital (Nembutal), phenobarbital (Luminal), ndi secobarbital (Seconal); khansa chemotherapy; okodzetsa (mapiritsi amadzi); epinephrine (Epipen); guanethidine (sikupezeka ku US); ipratropium (Atrovent); lifiyamu (Eskalith, Lithobid); mankhwala a nkhawa, matenda opweteka m'mimba, matenda amisala, kuyenda, matenda a Parkinson, zilonda zam'mimba, kapena mavuto amikodzo; mankhwala ogwidwa monga phenytoin (Dilantin); mankhwala osokoneza bongo opweteka; propranolol (mawonekedwe); mankhwala ogonetsa; mapiritsi ogona; ndi zotontholetsa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu ngati mwakhalapo kapena mwakhalapo ndi mphumu; emphysema (matenda am'mapapo omwe amapangitsa kupuma movutikira); matenda m'mapapu anu kapena machubu a bronchial (machubu omwe amabweretsa mpweya m'mapapu); kuvuta kusunga malire; glaucoma (momwe kupsyinjika kowonjezeka m'maso kumatha kubweretsa kuwonongeka pang'ono kwa masomphenya); khansa ya m'mawere; pheochromocytoma (chotupa pa kangaude kakang'ono pafupi ndi impso); kugwidwa; electroencephalogram yachilendo (EEG; mayeso omwe amalemba zamagetsi muubongo); vuto lililonse lomwe limakhudza kupanga maselo amwazi m'mafupa; kapena matenda a mtima, chiwindi, kapena impso. Uzaninso dokotala wanu ngati munasiya kumwa mankhwala a matenda amisala chifukwa cha zovuta zina kapena ngati mukufuna kugwira ntchito ndi tizilombo toyambitsa matenda a organophosphorus (mtundu wa mankhwala omwe amagwiritsidwa ntchito kupha tizilombo).
  • ngati mukugwiritsa ntchito chlorpromazine pochiza nseru ndi kusanza, ndikofunikira kuuza dokotala za zizindikiritso zina zomwe mukukumana nazo, makamaka kulephera; kusinza; chisokonezo; ndewu; kugwidwa; mutu; mavuto ndi masomphenya, kumva, kulankhula, kapena kusamala; kupweteka m'mimba kapena kukokana; kapena kudzimbidwa. Nsautso ndi kusanza zomwe zimachitika pamodzi ndi zizindikilozi zitha kukhala chizindikiro cha vuto lalikulu lomwe siliyenera kulandira mankhwala a chlorpromazine.
  • uzani dokotala wanu ngati muli ndi pakati, makamaka ngati muli m'miyezi ingapo yapitayo ya mimba yanu, kapena ngati mukufuna kutenga pakati kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga chlorpromazine, itanani dokotala wanu. Chlorpromazine imatha kubweretsa mavuto kwa ana obadwa kumene atabereka ngati atamwedwa m'miyezi yapitayi yamimba.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa chlorpromazine.
  • ngati mukuchita kafukufuku wa myelogram (x-ray) ya msana, uzani adotolo ndi wojambula kuti mukumwa mankhwala a chlorpromazine. Dokotala wanu mwina angakuuzeni kuti musamwe chlorpromazine masiku awiri isanachitike myelogram komanso tsiku limodzi pambuyo pa myelogram.
  • Muyenera kudziwa kuti mankhwalawa atha kukupangitsani kugona ndipo zingakhudze malingaliro anu ndi mayendedwe anu. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • Funsani dokotala wanu za kumwa mowa mosayenera mukamamwa mankhwala a chlorpromazine. Mowa umatha kukulitsa mavuto obwera chifukwa cha chlorpromazine.
  • konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Chlorpromazine imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.
  • Muyenera kudziwa kuti chlorpromazine imatha kuyambitsa chizungulire, kupepuka mutu, kugunda kwamtima, komanso kukomoka, makamaka mukadzuka msanga msangamsanga. Izi ndizofala kwambiri kumayambiriro kwa chithandizo cha mankhwala a chlorpromazine, makamaka pambuyo pa mlingo woyamba. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.
  • muyenera kudziwa kuti chlorpromazine imapangitsa kuti thupi lanu lizizizira kuzizira mukatentha kwambiri. Uzani dokotala wanu ngati mukufuna kuchita masewera olimbitsa thupi mwamphamvu kapena kutentha kwambiri.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Ngati mumamwa chlorpromazine nthawi zonse ndipo mwaphonya mlingo, tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Chlorpromazine imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • chizungulire, kumva kusakhazikika, kapena kukhala ndi vuto loti musamachite zinthu mopitirira malire
  • mawonekedwe opanda nkhope
  • kuyenda mosinthana
  • kusakhazikika
  • kubvutika
  • manjenje
  • kusuntha kosazolowereka, kosachedwa, kapena kosalamulirika kwa gawo lililonse la thupi
  • kuvuta kugona kapena kugona
  • kuchuluka kudya
  • kunenepa
  • kupanga mkaka wa m'mawere
  • kukulitsa mawere
  • anasiya kusamba
  • amachepetsa kuthekera kwakugonana
  • kusintha kwa khungu
  • pakamwa pouma
  • modzaza mphuno
  • kuvuta kukodza
  • kukulitsa kapena kuchepa kwa ophunzira (mabwalo akuda pakati pa maso)

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • malungo
  • kuuma minofu
  • kugwa
  • chisokonezo
  • kuthamanga kapena kusakhazikika kwamtima
  • thukuta
  • chikasu cha khungu kapena maso
  • zizindikiro ngati chimfine
  • zilonda zapakhosi, kuzizira, ndi zizindikiro zina za matenda
  • kutuluka mwachilendo kapena kuphwanya
  • kupweteka kwa khosi
  • lilime lomwe limatuluka pakamwa
  • zolimba pakhosi
  • kuvuta kupuma kapena kumeza
  • mayendedwe abwino, onga nyongolotsi
  • osalamulirika, nkhope, kamwa, kapena nsagwada
  • kugwidwa
  • matuza
  • zidzolo
  • ming'oma
  • kuyabwa
  • kutupa kwa maso, nkhope, pakamwa, milomo, lilime, mmero, mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
  • kutayika kwa masomphenya, makamaka usiku
  • kuwona zonse zokhala ndi bulauni

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Chlorpromazine ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

  • kugona
  • kutaya chidziwitso
  • kusuntha kosazolowereka, kosachedwa, kapena kosalamulirika kwa gawo lililonse la thupi
  • kubvutika
  • kusakhazikika
  • malungo
  • kugwidwa
  • pakamwa pouma
  • kugunda kwamtima kosasintha

Sungani maimidwe onse ndi dokotala komanso dokotala wanu wamaso. Muyenera kukhala ndi mayeso am'maso nthawi zonse mukamamwa mankhwala a chlorpromazine chifukwa chlorpromazine imatha kuyambitsa matenda amaso.

Musanapite kukayezetsa labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukumwa mankhwala a chlorpromazine.

Chlorpromazine imatha kusokoneza zotsatira za mayeso apakhomo. Lankhulani ndi dokotala ngati mukuganiza kuti mutha kukhala ndi pakati mukamamwa mankhwala a chlorpromazine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Kulimbikitsa®
  • Thorazine®

Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.

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