Anayankha

Zamkati

• Musanagwiritse ntchito jakisoni wa sargramostim,
• Sargramostim ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo izi:

Sargramostin imagwiritsidwa ntchito pochepetsa mwayi wopezeka ndi anthu omwe ali ndi khansa ya m'magazi (AML; mtundu wa khansa yamagazi oyera) ndipo amalandila mankhwala a chemotherapy omwe amachepetsa kuchuluka kwa ma neutrophils (mtundu wama cell amwazi wofunikira kumenya nkhondo matenda). Sargramostin imagwiritsidwanso ntchito kwa anthu omwe akudwala ma cell a magazi, mwa anthu omwe akupanga ma bone, ndikukonzekera magazi a leukapheresis (mankhwala omwe maselo ena amwazi amachotsedwa mthupi ndikubwezeretsanso thupi kutsatira chemotherapy). Sargramostim imagwiritsidwanso ntchito kwa anthu omwe sanayankhe atalandira magazi m'mafupa. Sargramostin ali mgulu la mankhwala otchedwa colony-stimulating factor. Zimagwira ntchito pothandiza thupi kupanga ma neutrophil ambiri ndi ma cell ena amwazi.

Sargramostim imabwera ngati yankho (madzi) kapena ufa wothira madzi kuti ubayire subcutaneously (pansi pa khungu) kapena kudzera m'mitsempha (mumtsempha). Amalowetsedwa (jekeseni pang'onopang'ono) kwa nthawi ya maola 2 mpaka 24 kamodzi tsiku lililonse. Itha kubayidwa kamodzi tsiku lililonse. Kutalika kwa chithandizo chanu kumadalira momwe muliri komanso momwe thupi lanu limayankhira ndi mankhwalawo.

Ngati mukugwiritsa ntchito sargramostim kuti muchepetse chiopsezo chotenga kachilombo ka chemotherapy, mudzalandira mankhwala osachepera masiku 4 mutalandira gawo lanu lomaliza la chemotherapy. Mupitiliza kulandira mankhwalawa tsiku lililonse mpaka kuchuluka kwama cell anu abwerere mwakale kapena kwa milungu isanu ndi umodzi. Ngati mukugwiritsa ntchito sargramostim kukonzekera magazi anu ku leukapheresis, mudzalandira mankhwala kamodzi tsiku lililonse mpaka leukapheresis yomaliza. Ngati mukugwiritsa ntchito sargramostim chifukwa mukukhala ndi ma cell a magazi, mudzalandira mankhwala kuyambira tsiku lobwezeretsa khungu lamagazi ndikupitilira kwa masiku atatu. Ngati mukugwiritsa ntchito sargramostim kuti muchepetse chiopsezo chotenga kachilomboka mukamayika mafuta m'mafupa, mudzalandira mankhwala osachepera maola 24 mutalandira chemotherapy komanso maola awiri kapena anayi pambuyo poti fupa ladzaza. Ngati mukugwiritsa ntchito sargramostim chifukwa simukuyankha pakuthira mafuta m'mafupa, mudzalandira mankhwalawa kamodzi patsiku kwa masiku 14. Osasiya kugwiritsa ntchito sargramostim osalankhula ndi dokotala.

Sargramostim itha kukupatsani namwino kapena wothandizira ena, kapena mungauzidwe kuti mulowe mankhwala kunyumba. Ngati mudzakhala mukubaya sargramostim, jambulani mankhwalawo nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Gwiritsani ntchito sargramostim ndendende momwe mwalangizira. Osamagwiritsa ntchito zocheperako kapena kuzigwiritsa ntchito pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukubaya jekeseni wa sargramostim nokha, wothandizira zaumoyo adzakuwonetsani momwe mungabayire mankhwalawo. Onetsetsani kuti mukumvetsetsa izi. Funsani wothandizira zaumoyo wanu ngati muli ndi mafunso okhudza komwe muyenera kubaya sargramostim, momwe mungaperekere jakisoni, jakisoni wamtundu wanji kuti mugwiritse ntchito, kapena momwe mungatayire masingano ndi majekeseni mutagwiritsa ntchito mankhwala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Sargramostim imagwiritsidwanso ntchito pochiza mitundu ina ya matenda a myelodysplastic (gulu la mafupa omwe mafupa am'magazi amatulutsa maselo am'magazi omwe samangidwa bwino ndipo samatulutsa ma cell amwazi okwanira) komanso kuperewera kwa magazi m'thupi (aplastic anemia) amatulutsa maselo atsopano okwanira). Sargramostim imagwiritsidwanso ntchito pochepetsa mwayi wopezeka ndi anthu omwe ali ndi kachilombo ka HIV. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa sargramostim,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi sargramostim, yisiti, mankhwala ena aliwonse, kapena zina zilizonse zophatikizira jakisoni wa sargramostim. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula betamethasone (Celestone), dexamethasone (Decadron), lithiamu (Lithobid), methylprednisolone (Medrol), ndi prednisone.Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani adotolo ngati mukumuthandizira kapena ngati mudalandirapo mankhwala a radiation kapena ngati mwakhalapo ndi khansa, edema (kutupa kwa m'mimba, mapazi, akakolo, kapena miyendo yakumunsi), mtundu uliwonse wamatenda amtima, kulephera kwa mtima , kugunda kwa mtima, mapapo, impso, kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito sargramostim, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukugwiritsa ntchito sargramostim.
• Muyenera kudziwa kuti sargramostim imachepetsa chiopsezo chotenga kachilombo, koma siyimateteza matenda onse omwe amayamba mkati kapena pambuyo pa chemotherapy. Itanani dokotala wanu nthawi yomweyo mukakhala ndi zizindikilo za matenda monga malungo, kuzizira, zilonda zapakhosi, kapena kutsokomola kosalekeza komanso kuchulukana.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Sargramostim ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kutupa, kufinya, kuyabwa kapena chotupa m'dera lomwe munabayidwa mankhwala
• kupweteka kwa mafupa, olowa, kapena minofu
• mutu
• nseru
• kusanza
• kutsegula m'mimba
• kupweteka m'mimba
• zilonda mkamwa
• kusowa chilakolako
• kutayika tsitsi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kupuma movutikira kapena kupuma mofulumira
• kuvuta kupuma
• kupuma
• chizungulire
• thukuta
• ming'oma
• zidzolo
• kuyabwa
• kutupa mozungulira pakamwa, nkhope, maso, mimba, mapazi, akakolo, kapena miyendo yakumunsi
• kunenepa mwadzidzidzi
• kupweteka pachifuwa
• kuthamanga kapena kusakhazikika kwamtima
• kukomoka
• mabala achilendo kapena zofiirira pansi pa khungu
• magazi osazolowereka
• mwazi wa m'mphuno
• kutopa kapena kufooka kosazolowereka
• kuchepa pokodza

Sargramostim ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, kutali ndi kuwala kwa dzuwa, kutsekedwa, komanso komwe ana sangakufikire. Sungani sargramostim mufiriji. Osazizira kapena kugwedeza sargramostim. Mitsempha yotsegulidwa ya sargramostim itha kukhala mufiriji kwa masiku 20. Tayani mbale zotseguka pakatha masiku 20.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kupuma movutikira
• kutopa kapena kufooka kosazolowereka
• malungo
• kuthamanga kapena kusakhazikika kwamtima
• nseru
• mutu
• zidzolo

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira ku sargramostim.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Leukine^®

• Cholimbikitsa cha Granulocyte-Macrophage Colony
• GM-CSF