Mlembi: William Ramirez
Tsiku La Chilengedwe: 22 Sepitembala 2021
Sinthani Tsiku: 16 Novembala 2024
Anonim
Gold-stavudine-PLGA nanoparticles - Video abstract: 38013
Kanema: Gold-stavudine-PLGA nanoparticles - Video abstract: 38013

Zamkati

Stavudine atha kuyambitsa matenda owopsa kapena owopsa a lactic acidosis (kumanga kwa asidi m'magazi) omwe angafunikire kuchiritsidwa kuchipatala. Chiwopsezo choti ungakhale ndi lactic acidosis chimakhala chachikulu ngati uli mzimayi, ngati uli wonenepa kwambiri, komanso ngati wathandizidwa ndi mankhwala a kachilombo ka HIV kwa nthawi yayitali. Chiwopsezo chikhoza kukhalanso chachikulu ngati muli ndi pakati ndipo mukumwa stavudine pamodzi ndi didanosine (Videx). Uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi, kuphatikiza matenda a kachilombo ka hepatitis C. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: nseru; kusanza; kusowa chilakolako; kutopa kwambiri; kufooka; chizungulire; mutu wopepuka; kuthamanga kapena kusakhazikika kwamtima; kuvuta kupuma; mkodzo wakuda wachikaso kapena bulauni; kutuluka mwachilendo kapena kuvulala; zizindikiro ngati chimfine; kusuntha kwamatumbo; chikasu cha khungu kapena maso; ululu kumtunda chakumanja kwa m'mimba mwanu; kumva kuzizira, makamaka m'manja kapena m'miyendo; kapena kupweteka kwa minofu kosiyana ndi ululu uliwonse wam'mimba womwe mumakumana nawo.


Stavudine imatha kuyambitsa matenda oopsa kapamba (kutupa kwa kapamba). Uzani dokotala wanu ngati mumamwa kapena mumamwa zakumwa zoledzeretsa zambiri komanso ngati mwakhala mukudwala kapamba. Musamwe mowa mukamamwa stavudine. Komanso uzani dokotala ngati mukumwa didanosine (Videx). Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo: kupweteka m'mimba kapena kutupa, nseru, kusanza, kapena malungo.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena kuti aone momwe thupi lanu lingayankhire pa stavudine.

Lankhulani ndi dokotala wanu za kuopsa kotenga stavudine.

Stavudine imagwiritsidwa ntchito limodzi ndi mankhwala ena kuchiza matenda a kachirombo ka HIV. Stavudine ali mgulu la mankhwala otchedwa nucleoside reverse transcriptase inhibitors (NRTIs). Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale kuti stavudine sachiza kachilombo ka HIV, imatha kuchepetsa mwayi wanu wopeza matenda a immunodeficiency (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga (kufalitsa) kachirombo ka HIV kwa anthu ena.


Stavudine amabwera ngati kapisozi komanso ngati yankho lakumwa (madzi) kuti atenge pakamwa. Amamwedwa kawiri patsiku (maola 12 aliwonse), wopanda kapena wopanda chakudya komanso ndi madzi ambiri. Kukuthandizani kukumbukira kukumbukira kutenga stavudine, imwani mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani stavudine ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukupereka yankho lakumlomo kwa mwana, sinthani botolo musanagwiritse ntchito kusakaniza mankhwala mofanana. Gwiritsani ntchito chikho choyezera kuti mupime kuchuluka kwa mwana.

Stavudine amalamulira kachilombo ka HIV koma samachiza. Pitilizani kutenga stavudine ngakhale mukumva bwino. Osasiya kumwa ma stavudine osalankhula ndi dokotala. Stavudine yanu ikayamba kuchepa, pezani zambiri kuchokera kwa dokotala kapena wamankhwala. Ngati mwaphonya Mlingo kapena mwadzidzidzi mwasiya kumwa stavudine, matenda anu akhoza kukhala ovuta kuchiza.


Stavudine nthawi zina amagwiritsidwanso ntchito limodzi ndi mankhwala ena opewera kutenga kachirombo ka HIV mwa ogwira ntchito zaumoyo kapena anthu ena omwe adapezeka ndi HIV mwangozi. Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanatenge stavudine,

  • uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi stavudine, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a stavudine kapena yankho lamlomo. Funsani wamankhwala anu kuti awonetse mndandanda wazosakaniza kapena onani malangizo a mankhwala.
  • Uzani dokotala ndi wazamankhwala mankhwala omwe mukulandira komanso osapereka mankhwala, mavitamini, zowonjezera zakudya ndi mankhwala azitsamba omwe mukumwa. Onetsetsani kuti mwatchula omwe adatchulidwa mu gawo LOFUNIKA CHENJEZO ndi doxorubicin, hydroxyurea (Droxia, Siklos), ribavirin (Rebetol, Ribasphere), kapena zidovudine (Retrovir, ku Combivir, inTrizivir). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala pazotsatira.
  • Uzani dokotala wanu ngati mukulandira mankhwala a dialysis kapena ngati mwakhalapo ndi matenda a impso, matenda ashuga, kapena zotumphukira (mtundu wa kuwonongeka kwa mitsempha komwe kumayambitsa kulira, dzanzi, ndi kupweteka m'manja ndi m'mapazi).
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga stavudine, itanani dokotala wanu. Simuyenera kuyamwa ngati muli ndi kachilombo ka HIV kapena ngati mukumwa stavudine.
  • muyenera kudziwa kuti stavudine imatha kubweretsa zovuta zomwe zimayenera kuthandizidwa nthawi yomweyo zisanachitike. Ana omwe amamwa stavudine sangathe kukuwuzani za zovuta zomwe akumva. Ngati mukupereka stavudine kwa mwana, funsani adotolo a mwanayo momwe mungadziwire ngati mwanayo ali ndi zotsatirapo zoyipa izi.
  • muyenera kudziwa kuti mutha kutaya mafuta amthupi kumaso, miyendo, ndi mikono. Lankhulani ndi dokotala mukawona kusintha uku.
  • muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mutayamba kumwa mankhwala ndi stavudine, onetsetsani kuti mwauza dokotala wanu.
  • ngati muli ndi matenda ashuga, muyenera kudziwa kuti pali 50 mg ya sucrose mu supuni iliyonse (5 mL) yankho la mkamwa la stavudine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Stavudine amatha kuyambitsa zovuta zina. Uzani dokotala wanu ngati chimodzi mwazizindikirozi ndi zoopsa kapena sichitha:

  • mutu
  • kutsegula m'mimba
  • zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zizindikiro zotsatirazi kapena zina mwazomwe zalembedwa mu gawo la CHENJEZO LOFUNIKA, itanani dokotala wanu mwachangu:

  • dzanzi, kumva kulasalasa, kutentha kapena kupweteka m'manja kapena m'mapazi
  • zovuta kusuntha manja ndi mapazi

Stavudine amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani makapisozi kutentha ndikutentha ndi kutentha kwambiri ndi chinyezi (osati kubafa). Sungani yankho lanu pakamwa mufiriji ndikuchotsa gawo lomwe simunagwiritse ntchito pakatha masiku 30.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • dzanzi, kumva kulasalasa, kufooka, kapena kupweteka m'manja kapena m'mapazi
  • kusanza
  • zachilendo kapena zosayembekezereka kupweteka m'mimba
  • kufooka kapena kutopa
  • kupuma movutikira

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Khalani ndi stavudine pafupi. Musayembekezere mpaka mutatsala pang'ono kumwa mankhwala kuti mudzaze mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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