Kampaniyi Imapatsa Mayeso a Chibadwa Kunyumba Kwawo

Zamkati

• Momwe Mayeso Amagwirira Ntchito
• Zapamwamba
• The Drawbacks
• Ndani Ayenera Kuyesedwa?
• Onaninso za

Mu 2017, mutha kupeza mayeso a DNA pachilichonse chokhudza thanzi. Kuchokera pamatumbo omwe amakuthandizani kudziwa mtundu wanu wathanzi pakuyesedwa kwa magazi komwe kumakuuzani zomwe zingakhale zakudya zabwino kwambiri pakuchepetsa, zosankhazo ndizosatha. CVS imanyamulanso mayeso a DNA opita kunyumba ndi 23andMe omwe amawonetsa majini okhudzana ndi kulemera, kulimba, komanso thanzi. Ndiyeno, ndithudi, pali zoyezetsa majini kuti chiwopsezo chowonjezereka cha matenda aakulu, monga khansara, Alzheimer's, komanso matenda a mtima. Momwemonso, mayeserowa amalimbikitsa anthu kudziwa zambiri zomwe zingawathandize kupanga zisankho zabwino pankhani yazaumoyo wawo, koma kuwonjezeka kwa mwayi wofikira kumabweretsa mafunso, monga "Kodi mayeso apanyumba ndi othandiza ngati omwe amachitika kuchipatala?" Ndipo "Kodi kudziwa zambiri za DNA yanu nthawi zonse ndichinthu chabwino?" (Zogwirizana: Chifukwa Chomwe Ndinapezera Kuyesedwa kwa Alzheimer's)

Posachedwa, kampani yatsopano yothandizira zaumoyo yotchedwa Colour idakhazikitsa mayeso oyimitsa a BRCA1 ndi BRCA2. Mayeso a malovu amangotengera $99, ndipo mutha kuyitanitsa pa intaneti. Ngakhale ndichinthu chabwino kuti anthu ambiri adziwe zamtundu wawo wa khansa ya m'mawere ndi yamchiberekero (khansa ziwirizo BRCAKusintha kwa majini kumalumikizidwa ndi), akatswiri oyesa majini amadandaula kuti mayesowa athe kupezeka kwa anthu popanda kupatsa odwala zinthu zoyenera.

Momwe Mayeso Amagwirira Ntchito

Chimodzi mwazinthu zabwino kwambiri pamayeso amtundu wa Colour ndikuti amalamulidwa ndi dokotala. Izi zikutanthauza kuti musanayese mayeso, muyenera kukambirana ndi adokotala-anu kapena dokotala woperekedwa ndi kampani-pazomwe mungachite. Kenaka, zidazo zimatumizidwa kunyumba kwanu kapena ku ofesi ya dokotala wanu, mumatsuka mkati mwa tsaya lanu kuti mupeze chitsanzo cha malovu, ndipo mumatumiza ku labu ya Colour kuti mukayesedwe. Pakadutsa milungu itatu kapena inayi, mumalandira zotsatira zanu, limodzi ndi mwayi wolankhula ndi mlangizi wama foni pafoni. (Zokhudzana: Khansa Yam'mawere Ndi Chiwopsezo Chazachuma Palibe Amene Akuyankhula)

Zapamwamba

Ngakhale akuti 1 mwa anthu 400 ali ndi kusintha kwa BRCA1 kapena BRCA2, zikuwerengedwanso kuti oposa 90 peresenti ya anthu omwe akhudzidwa sanadziwikebe. Izi zikutanthauza kuti anthu ambiri akuyenera kuyesedwa; nthawi. Popangitsa kuti mayesowo apezeke pamtengo wotsika mtengo kwa anthu omwe mwina sangathe kuyesa, Colour ikuthandiza kutseka kusiyana kumeneku.

Kawirikawiri, ngati mukufuna kuyesa BRCA kudzera mwa dokotala wanu, muyenera kugwera m'magulu atatu, malinga ndi Ryan Bisson, mlangizi wa chibadwa ku Orlando Health UF Health Cancer Center. Choyamba, ngati muli ndi khansa ya m'mawere kapena yamchiberekero. Chachiwiri, ngati pali mbiri ya banja linalake monga wachibale yemwe ali ndi khansa ya m'mawere kapena wachibale amene ali ndi khansa ya m'mawere ali ndi zaka 45 kapena asanakwanitse. njira. Mtundu umapereka mwayi kwa anthu omwe sagwera mgululi.

Kampaniyo imadaliridwanso ndi magulu akuluakulu azaumoyo amtunduwu woyeserera zamtunduwu komanso munthawi zina, zomwe zikutanthauza kuti simuyenera kuda nkhawa za mtundu wa mayeso a Mtundu. "Dipatimenti ya Henry Ford ya Medical Genetics imagwiritsa ntchito Colour kwa anthu omwe akufuna kukayezetsa koma osakwaniritsa njira zoyesera, komanso azimayi omwe safuna zotsatira zakuyesera pazolemba zawo zamankhwala," akufotokoza a Mary Helen Quigg, MD, dokotala ku Dipatimentiyi. wa Medical Genetics ku Henry Ford Health System. Nthawi zina, anthu safuna kuti zotsatira zawo zilembedwe pazolinga za inshuwaransi. Kuphatikiza apo, pali chinthu chothandizira, akutero Dr. Quigg. Kuyesa kunyumba ndikwachangu komanso kosavuta.

The Drawbacks

Ngakhale pali zinthu zina zazikuluzikulu pazomwe zimayesedwa kunyumba kwa BRCA, akatswiri amatchula mavuto anayi akuluakulu.

Anthu ambiri ali ndi malingaliro olakwika okhudza zomwe kuyezetsa majini kumatanthauza pachiwopsezo chonse cha khansa.

Nthawi zina anthu amayang'ana kuyezetsa majini kuti apereke mayankho ochulukirapo kuposa momwe angathere. "Ndine wochirikiza odwala omwe amadziwa zambiri za majini awo," akutero Bisson. Koma "makamaka chifukwa cha khansa, anthu amaika kwambiri ma genetics. Amaganiza kuti khansa yonse imachitika chifukwa cha majini awo ndipo kuti ngati atayesedwa, adzawauza zonse zomwe akufunikira kudziwa." Zoonadi, pafupifupi 5 mpaka 10 peresenti ya khansa ndi chifukwa cha kusintha kwa majini, kotero pamene kuli kofunika kumvetsetsa chiopsezo chanu choloŵa, kupeza zotsatira zoipa sikukutanthauza kuti simudzakhala ndi khansa. Ndipo ngakhale zotsatira zabwino zikuwonetsa chiwopsezo chowonjezeka, sizitanthauza inu ndidzatero kupeza khansa.

Zikafika pakuyezetsa majini, kupeza kulondola mayesero ndi ofunikira.

Mayeso a BRCA operekedwa ndi Colour atha kukhala otakata kwambiri kwa anthu ena, komanso ochepera ena. "BRCA 1 ndi 2 zimangokhala pafupifupi 25% ya khansa ya m'mawere yotengera," malinga ndi Dr. Quigg.Izi zikutanthauza kuti kungoyesa kusintha kwachiwiri kumeneku kungakhale kwachindunji kwambiri. Quigg ndi anzawo akafuna kuyesedwa kuchokera ku Colour, nthawi zambiri amayesa mayeso ochulukirapo kuposa BRCA 1 ndi 2, nthawi zambiri amasankha mayeso awo a Hereditary Cancer Test, omwe amafufuza ma jini 30 omwe amadziwika kuti ali ndi khansa.

Kuphatikiza apo, zotsatira zothandiza kwambiri zimachokera ku mayeso okhazikika. "Tili ndi majini pafupifupi 200 okhudzana ndi khansa," akufotokoza Bisson. "Kuchokera kuchipatala, timapanga mayeso ozungulira zomwe tikuwona m'mbiri yanu komanso banja lanu." Chifukwa chake nthawi zina, gulu la jini 30 litha kukhala lachindunji kapena lotakata kwambiri, kutengera mbiri yabanja lanu.

Kuphatikiza apo, ngati wachibale wa munthu wayesedwa kale kuti ali ndi HIV, mayeso a BRCA si njira yabwino kwambiri. "Ganizirani za majini a BRCA ngati buku," akutero Bisson. "Ngati tipeza masinthidwe m'modzi mwa majini amenewo, labu yomwe idayesayo itiuza nambala yatsamba yomwe masinthidwewo ali, ndiye kuyesa wina aliyense m'banjamo nthawi zambiri kumangoyang'ana masinthidwe amodziwo kapena 'nambala yatsamba. . ' Izi zimadziwika ngati kuyesa kwa tsamba limodzi, komwe kumachitika ndi Colour kudzera kwa dokotala koma sikuperekedwa kwa anthu wamba patsamba lawo.

Simukuyenera kulipira kunja kwa thumba poyezetsa majini.

Ndizowona kuti anthu ambiri ayenera kuyezetsa BRCA, koma monga momwe mayesowo ayenera kulunjika mwachindunji, anthu omwe amayesedwa ayenera kuchokera ku gulu linalake: anthu omwe amakwaniritsa zofunikira zoyezetsa. "Odwala nthawi zina amawona njirazo ngati chinthu china choti iwo adumphe, koma zikuyesera kulunjika mabanja omwe atha kupeza chidziwitso pakuwunika kwa majini," akutero a Bisson.

Ndipo ngakhale mayesowo ndi okwera mtengo osakwana $ 100, Mtundu sapereka mwayi wokhala ndi inshuwaransi pamayeso oyimira a BRCA. (Amapereka mwayi woti angalipire inshuwaransi pamayeso ena ena.) Ngati mungakwaniritse zofunikira pakuyesedwa kwa majini ndipo muli ndi inshuwaransi yazaumoyo, palibe chifukwa cholipirira mthumba kuti mukayezetse majini pakusintha kwa BRCA zachitika. Ndipo ngati inshuwaransi yanu siyikuphimba kuyesa? "Nthawi zambiri, awa ndi anthu omwe sangapindule ndi kuyesa. Makampani ambiri a inshuwalansi amagwiritsa ntchito njira za dziko kuchokera ku National Comprehensive Cancer Network, yomwe ndi gulu la madokotala odziimira okha ndi akatswiri omwe amapanga malangizowo, "akutero Bisson. Zachidziwikire, nthawi zonse pamakhala kusiyanasiyana, ndipo kwa anthu amenewo, Bisson akuti mungatero amalangiza ntchito ngati Mtundu.

Upangiri wa chibadwa mutapeza zotsatira zanu ndiyofunikira.

Nthawi zina zotsatira zoyesa majini zimatha kubweretsa mafunso ambiri kuposa mayankho. Pamene kusintha kwa majini (kapena kusintha kwa jini) kumapezeka, pali njira zitatu zomwe zitha kusankhidwa, malinga ndi Bisson. Benign, zomwe zikutanthauza kuti ndizopanda vuto. Pathogenic, zomwe zikutanthauza kuti zimawonjezera chiopsezo cha khansa. Ndipo kusiyanasiyana kosadziwika bwino (VUS), zomwe zikutanthauza kuti palibe kafukufuku wokwanira wokhudza kusinthaku kuti athe kutsimikizira. "Pali pafupifupi 4 mpaka 5% mwayi wopeza VUS yoyesedwa ndi BRCA," akutero a Bisson. "Kwa odwala ambiri, ndizokwera kwambiri kuposa mwayi wopeza kusintha kwa pathogenic." Kumbukirani kuti imodzi mwa malamulo 400 kuyambira kale? Izi zikutanthauza kuti ndizotheka kuti popanda njira zoyeserera, mwina simungapeze zambiri zamtunduwu. Ichi ndi chimodzi mwazifukwa zazikulu zomwe makampani a inshuwaransi nthawi zambiri amafuna kuti anthu azikumana ndi akatswiri azachipatala kapena mlangizi asanayezedwe.

Mtundu umapereka uphungu wa majini, koma umapezeka makamaka pambuyo poyesedwa. Kwa iwowo, amalankhula momveka bwino kuti muyenera kukambirana zotsatira zanu ndi achipatala, koma sikofunikira. Nkhani ndi yakuti nthawi zambiri anthu amangoyitanira uphungu akalandira zotsatira zabwino, akutero Dr. Quigg. "Zotsatira zoyipa ndi mitundu yosiyanasiyana imafunikiranso upangiri kuti munthuyo amvetsetse tanthauzo lake. Zotsatira zoyipa sizitanthauza kuti palibe kusintha. Zingatanthauze kuti sitinapeze kusinthako - kapena kuti ndiko kwenikweni. negative." Zotsatira za VUS ndi thumba lina lonse la mphutsi lomwe limafunikira upangiri winawake, akutero.

Ndani Ayenera Kuyesedwa?

Mwachidule, ngati muli ndi inshuwaransi komanso mbiri yabanja yovomerezeka ya khansa yokhudzana ndi BRCA, mutha kuyezetsa kudzera munjira zachikhalidwe pamtengo wotsika kapena osalipira konse. Koma ngati inu musatero muli ndi inshuwaransi ndipo mumasowa poyesa kuyesa, kapena ngati simukufuna zotsatira zanu pazakuchipatala, mayeso a BRCA a Colour akhoza kukhala oyenera kwa inu. (Ngakhale mutakhala pachiwopsezo chotani, mudzafuna kudziwa za chida chowala cha pinki chomwe chimati chitha kuthandiza kuzindikira khansa ya m'mawere kunyumba.) Koma sizitanthauza kuti muyenera kungopita pa intaneti ndikukaitanitsa. "Ndimalimbikitsa odwala kuti alandire uphungu komanso ndiye asankhe ngati akufuna kukayezetsa kunyumba, ndi njira zina zopezera upangiri wotsatira, "akutero Dr. Quigg.

Mfundo yofunika: Lankhulani ndi dokotala musanalowe m'malo. Atha kukuthandizani kudziwa ngati kuyesa kukupatsani chidziwitso chomwe chingakuthandizeni ndikukutumizirani kwa mlangizi wamtundu. Ndipo ngati inu chitani kusankha kusankha kunyumba, dokotala wanu akhoza kulankhula nanu zotsatira zanu maso ndi maso.

Onaninso za