Zowonongeka za Lobular Carcinoma: Zizindikiro, Chithandizo, ndi Zambiri

Zamkati

• Kodi invasive lobular carcinoma (ILC) ndi chiyani?
• Zizindikiro za khansa ya m'mawere
• Zomwe zimayambitsa khansa ya m'mawere
• Zowopsa
• Lobular carcinoma in situ (LCIS)
• Kodi khansa ya m'mawere imapezeka bwanji?
• Makanema
• Kuwonetsa ILC
• Kodi khansa ya m'mawere imachiritsidwa bwanji?
• Njira zochiritsira komanso zowonjezera
• Ndingapewe bwanji khansa ya m'mawere?
• LCIS
• Kodi ndingapeze kuti magulu othandizira?
• Chiwonetsero

Kodi invasive lobular carcinoma (ILC) ndi chiyani?

Invasive lobular carcinoma (ILC) ndi khansa m'matumba opanga mkaka. Anthu omwe ali ndi ILC sangamveke zotupa. Amadziwikanso kuti kulowetsa lobular carcinoma kapena khansa ya m'mawere.

ILC imakula ndikufalikira mosiyana ndi mitundu ina ya khansa ya m'mawere monga invasive ductal carcinoma (IDC), kapena khansa yamayendedwe amkaka.

Khansa ikafalikira, imatchedwa metastatic. Ku ILC, khansara imayamba m'mabere a mawere ndikusunthira kumatenda oyandikana nawo. Itha kupita ku ma lymph node ndi ziwalo zina m'thupi.

Azimayi opitilira 180,000 ku United States chaka chilichonse amalandila matenda a khansa ya m'mawere. ILC imapanga pafupifupi 10 peresenti ya omwe amapezeka.

Zizindikiro za khansa ya m'mawere

ILC imayamba mosiyana ndi mitundu yodziwika bwino ya khansa ya m'mawere. Sizingatheke kukhala ndi ziphuphu zoonekeratu. Kumagawo oyambilira, sipangakhale zizindikilo kapena zizindikilo. Koma khansa ikamakula, mutha kuwona mawere anu:

• kuuma kapena kuumitsa mdera lina
• kutupa kapena kumverera kodzaza ndi malo enaake
• kusintha kapangidwe kake kapena khungu, monga kupindika
• kupanga nipple yatsopano
• kusintha kukula kapena mawonekedwe

Zizindikiro zina zitha kuphatikiza:

• kupweteka kwa m'mawere
• kupweteka kwa mawere
• kutulutsa kupatula mkaka wa m'mawere
• chotchinga mozungulira malowa

Izi nthawi zambiri zimakhala zizindikiro zoyambirira za khansa ya m'mawere, kuphatikizapo ILC. Onani dokotala ngati mutawona izi.

Zomwe zimayambitsa khansa ya m'mawere

Zomwe zimayambitsa ILC sizikudziwika. Koma khansa yamtunduwu imayamba pomwe maselo am'magazi anu opanga mkaka amapanga kusintha kwa DNA komwe kumalamulira kukula kwa maselo ndi kufa.

Maselo a khansa amayamba kugawanika ndikufalikira ngati nthambi, ndichifukwa chake simungathe kumva chotupa.

Zowopsa

Mwayi wopeza ILC ukuwonjezeka ngati muli:

• chachikazi
• pa ukalamba, kuposa mitundu ina ya khansa ya m'mawere
• mayi yemwe ali ndi mankhwala obwezeretsa mahomoni (HRT), makamaka atatha kusamba
• okhala ndi majini a khansa obadwa nawo

Lobular carcinoma in situ (LCIS)

Chiwopsezo chanu chokhala ndi ILC chitha kukulirakulira ngati mwapezeka ndi LCIS. LCIS ​​ndipamene amapezeka ma cell atypical kapena abnormal, koma maselowa amangokhala m'makola ndipo sanalowerere minofu ya m'mawere.

LCIS ​​si khansa ndipo imadziwika kuti ndi yachilendo.

Kodi khansa ya m'mawere imapezeka bwanji?

Madokotala anu adzagwiritsa ntchito mayeso angapo ojambula kuti athandizire kupeza khansa ya m'mawere. Mayesowa akuphatikizapo:

• akupanga
• MRI
• mammogram
• chifuwa cha m'mawere

ILC ili ndi timagulu tating'onoting'ono, tomwe timadalira mawonekedwe am'munsi mwa microscope. Mu mtundu wakale wa ILC, maselowa amakhala mu fayilo imodzi.

Mitundu ina yakukula kwambiri ndi iyi:

• olimba: amakula ndi mapepala akuluakulu
• nthawi zonse: Amakula m'magulu a maselo 20 kapena kuposa
• tubulolobular: maselo ena amapangika ngati mafayilo amtundu umodzi ndipo ena amakhala ngati mapangidwe a chubu
• pachimake: chokulirapo kuposa ILC yakale yokhala ndi ma nuclei omwe amawoneka osiyana ndi anzawo
• selolo ya mphete: maselo amadzazidwa ndi ntchofu

Makanema

Mammograms atha kupereka zotsatira zabodza za khansa ya lobular. Izi ndichifukwa choti, mu X-ray, khansa ya lobular imawoneka yofanana ndi minofu yabwinobwino.

ILC imafalikiranso kudzera m'matumbo mosiyana ndi IDC.

Zotupa zopangidwa bwino komanso mayikidwe a calcium sizofala, zomwe zimapangitsa kuti katswiri wa radiyo azitha kusiyanitsa ILC ndi mnofu wamagulu wamba pa mammogram.

Zimakhalanso zotheka kukhala m'malo opitilira chimodzi a m'mawere kapena m'mawere onse awiri. Ngati ziwoneka pa mammogram, zitha kuwoneka zazing'ono kuposa momwe zilili.

Kuwonetsa ILC

Kuyala pachifuwa ndipamene dokotala amakudziwitsani momwe khansara yayendera kale kapena momwe yafalikira kuchokera pachifuwa.

Kusanja kutengera:

• kukula kwa chotupacho
• ndi ma lymph node angati omwe akhudzidwa
• kaya khansara yafalikira mbali zina za thupi

Pali magawo anayi a ILC, kuyambira 1 mpaka 4.

Monga IDC, ngati ILC ikufalikira, imawonekera mu:

• ma lymph node
• mafupa
• chiwindi
• mapapo
• ubongo

Mosiyana ndi IDC, ILC imatha kufalikira m'malo achilendo monga:

• mimba ndi matumbo
• akalowa m'mimba
• ziwalo zoberekera

Kuti mudziwe ngati maselo a khansa afalikira, adokotala amatha kuyitanitsa mayeso kuti muwone zam'mimba, magazi, ndi chiwindi.

Kodi khansa ya m'mawere imachiritsidwa bwanji?

Chithandizo chanu chabwino kwambiri chimadalira khansa yanu, zaka zanu, komanso thanzi lanu. Kuchiza ILC nthawi zambiri kumafuna kuchitidwa maopareshoni ndi mankhwala owonjezera.

Kusankha dotolo wanu mosamala ndikofunikira makamaka chifukwa cha kukula kwachilendo kwa ILC. Katswiri wochita opaleshoni wodziwa kuchiritsa odwala ILC ndichofunikira.

Kuchita maopaleshoni ocheperako ngati lumpectomy kumakhala ndi zotsatira zofananira ndi mankhwala amwano ngati mastectomy.

Lumpectomy ikhoza kukhala njira yabwino ngati gawo lochepa chabe la bere liri ndi khansa (mu opaleshoniyi, dokotalayo amangochotsa minofu ya khansa).

Ngati minofu yambiri ya m'mawere ikuphatikizidwa, dokotala wanu angakulimbikitseni mastectomy (kuchotsa mawere kwathunthu).

Zosankha zina zimaphatikizapo kuchotsa ma lymph node pafupi ndi bere lanu, njira yotchedwa sentinel lymph node biopsy, ndi armpit, yotchedwa axillary lymph node dissection.

Mungafunike chithandizo china, monga radiation, hormonal therapy, kapena chemotherapy, kuti muchepetse chiopsezo cha khansa yomwe ikubweranso pambuyo pochitidwa opaleshoni.

Njira zochiritsira komanso zowonjezera

Ngakhale mankhwala owonjezera komanso othandizira (CAM) sadziwika kuti amachiza khansa ya m'mawere, atha kuthandiza kuthana ndi zizindikilo zina ndi zoyipa za khansa ndi mankhwala ake.

Mwachitsanzo, anthu omwe amamwa mankhwala a khansa ya m'mawere amatha kutentha, kapena kutentha kwadzidzidzi, ndi thukuta.

Mutha kupeza mpumulo kudzera:

• kusinkhasinkha
• zowonjezera mavitamini
• zosangalatsa
• yoga

Nthawi zonse lankhulani ndi dokotala musanayese mankhwala atsopano kapena othandizira. Amatha kulumikizana ndi chithandizo chanu cham'mbuyomu ndikupangitsa zotsatirapo zosayembekezereka.

Thandizo la mahomoni (HT) lingalimbikitsidwe ngati maselo anu a khansa amatha kudziwa za mahomoni monga estrogen ndi progesterone.

Izi ndimomwe zimachitikira khansa ya m'mawere. HT imatha kuletsa mahomoni amthupi lanu kuti asawonetse ma cell a khansa kuti akule.

Ndingapewe bwanji khansa ya m'mawere?

Lobular carcinoma, monga khansa zina za m'mawere, zimatha kukhala ndi anthu athanzi. Mutha kuchepetsa chiopsezo chanu mwa:

• kumwa mowa pang'ono, ngati ndi choncho
• kudzipima mayeso
• kupeza mayeso apachaka, kuphatikiza mammograms
• kukhala wathanzi labwino
• kudya chakudya chamagulu komanso kuchita masewera olimbitsa thupi pafupipafupi

Ngati mukuganiza za HRT, kambiranani ndi dokotala za kuopsa ndi phindu la mankhwalawa. HRT itha kubweretsa chiopsezo cha lobular carcinoma ndi mitundu ina ya khansa ya m'mawere.

Ngati mungasankhe kutenga HRT, muyenera kumwa mankhwala otsika kwambiri kwakanthawi kochepa kotheka.

LCIS

Kodi ndingapeze kuti magulu othandizira?

Kupeza matenda amtundu wa khansa yamtundu uliwonse kungakhale kovuta. Kuphunzira za khansa ya m'mawere ndi chithandizo chomwe mungasankhe kungakuthandizeni kuti muzimasuka mukamayenda ulendo wanu.

Malo omwe mungapemphe thandizo ngati mutapezeka kuti muli ndi khansa ya m'mawere ndi awa:

• gulu lanu lachipatala
• abwenzi ndi abale
• midzi yapaintaneti
• magulu othandizira am'deralo

Pali chiopsezo chowonjezeka chokhala ndi khansa ya m'mawere ngati mwapezeka ndi LCIS. Mutha kumwa mankhwala, monga tamoxifen, kuti muchepetse chiopsezo chanu.

Dokotala wanu amathanso kunena za mastectomy ngati muli ndi mbiri yabanja ya khansa ya m'mawere.

Gulu la khansa ya m'mawere limawoneka komanso lomveka. Magulu othandizira am'deralo atha kukhala othandiza polumikizana ndi ena omwe akukumana ndi zomwezi.

Chiwonetsero

Kuzindikira koyambirira komanso kupita patsogolo kwa chithandizo kumathandizira kuti mukhale ndi mwayi wokhala ndi moyo wautali komanso wathanzi. Kuwona kwakanthawi kwa ILC kumadalira pazinthu zingapo, monga:

• siteji ya khansa
• kalasi ndi subtype
• ma margins, kapena momwe ma khansa amayandikira pafupi ndi minofu yomwe yatulutsidwa pachifuwa
• zaka zanu
• thanzi lanu lonse
• momwe mumayankhira kuchipatala

China chomwe chimakhudza zotsatira mu ILC ndikuti estrogen, progesterone, kapena HER2 (zotupa za epidermal kukula factor receptor 2) zimapezeka pamwamba pamaselo a khansa.