Kodi mayeso a GH ndi ati ndipo amafunikira liti

Zamkati

• Ndi chiyani
• Zatheka bwanji

Hormone yokula, yotchedwanso GH kapena somatotropin, ndi mahomoni ofunikira omwe amapangidwa ndi vuto la pituitary lomwe limagwira pakukula kwa ana ndi achinyamata komanso limagwira nawo gawo lama metabolism.

Kuyesaku kumachitika ndi kuchuluka kwa magazi m'magazi omwe amasonkhanitsidwa mu labotale ndipo nthawi zambiri amafunsidwa ndi a endocrinologist pakakhala kukayikira zakusowa kwa GH, makamaka kwa ana omwe amakula mopitirira momwe amayembekezeredwa, kapena kuchuluka kwake , wamba mu gigantism kapena acromegaly.

Kugwiritsa ntchito GH ngati mankhwala kumawonetsedwa pakakhala vuto pakupanga hormone iyi, mwa ana kapena akulu, monga akuwonetsera adotolo. Kuti mudziwe zambiri za momwe amagwiritsidwira ntchito, mitengo ndi zotsatira za kukula kwa hormone, onani chizindikiro cha mahomoni GH.

Ndi chiyani

Mayeso a GH amafunsidwa ngati mukukayikira:

• Kuzindikira, komwe ndiko kuchepa kwa mahomoni okula mwa ana, ndikupangitsa kukula kwakanthawi kochepa. Mvetsetsani chomwe chili komanso chomwe chingayambitse kuchepa;
• Kulephera kwa akuluakulu a GH, zomwe zimayambitsidwa ndi GH yocheperako bwino, yomwe imabweretsa zizindikilo monga kutopa, kuchuluka kwamafuta, kuchepa kwamafuta, kuchepa mphamvu zolimbitsa thupi, kuchepa kwa mafupa komanso chiwopsezo chokhala ndi matenda amtima;
• Zosangalatsa, wodziwika ndi kuchuluka kwa katulutsidwe ka GH mwa mwana kapena wachinyamata, zomwe zimapangitsa kukula kopitilira muyeso;
• Zosintha, omwe ndi matenda omwe amayamba chifukwa cha kuchuluka kwa GH mwa akulu, ndikupangitsa kusintha kwa khungu, manja, mapazi ndi nkhope. Onaninso kusiyana pakati pa acromegaly ndi gigantism;

Kuperewera kwa GH mthupi kumatha kukhala ndi zifukwa zingapo, monga matenda amtundu, kusintha kwa ubongo, monga zotupa, matenda kapena zotupa kapena chifukwa cha chemo kapena cheza chaubongo, mwachitsanzo. Kuchuluka kwa GH, komano, nthawi zambiri kumachitika chifukwa cha pituitary adenoma.

Zatheka bwanji

Kuyeza kwa mahomoni a GH kumachitika pofufuza magazi m'magulu a labotale ndipo amachitika m'njira ziwiri:

1. Muyeso wa GH muyeso: imachitika ndi maola 6 osala kudya kwa ana ndi maola 8 a achinyamata ndi achikulire, omwe amawunika kuchuluka kwa hormone iyi munthawi yamagazi;
2. Kuyesedwa kokakamiza kwa GH (ndi Clonidine, Insulin, GHRH kapena Arginine): zimachitika pogwiritsa ntchito mankhwala omwe angalimbikitse kutsekemera kwa GH, kukayikira zakusowa kwa hormone iyi. Kenako, kusanthula kwa ndende ya GH kumachitika pambuyo pa mphindi 30, 60, 90 ndi 120 zogwiritsa ntchito mankhwalawa.

Kuyeserera kwa GH ndikofunikira chifukwa kupanga kwa mahomoni a GH ndi thupi sikufanana, ndipo kumatha kusokonezedwa ndi zinthu zingapo, monga kusala, kupsinjika, kugona, kusewera masewera kapena kuchuluka kwa shuga m'magazi. Chifukwa chake, mankhwala ena omwe amagwiritsidwa ntchito ndi Clonidine, Insulin, Arginine, Glucagon kapena GHRH, mwachitsanzo, omwe amalimbikitsa kapena kuletsa kupanga kwa hormone.

Kuphatikiza apo, adokotala amathanso kuyitanitsa mayeso ena, monga kuyeza kwamahomoni monga IGF-1 kapena IGFBP-3 protein, yomwe imasintha ndi kusiyanasiyana kwa GH: Kujambula kwa MRI kwaubongo, kuti iwunikenso kusintha kwa matenda am'mimba, nawonso zitha kukhala zothandiza kuzindikira chomwe chayambitsa vutoli.