: ndi chiyani, zizindikiro, matenda ndi chithandizo

Zamkati

• Zizindikiro za matenda mwa Fusarium spp.
• Matenda opatsirana ali bwanji
• Momwe matendawa amapangidwira
• Chithandizo cha Fusariosis

Fusariosis ndi matenda opatsirana omwe amabwera chifukwa cha bowa wopezera mwayi, a Fusarium spp., Zomwe zimapezeka m'chilengedwe, makamaka m'minda. Matenda ndi Fusarium spp. imachitika pafupipafupi kwa anthu omwe ali ndi chitetezo chamthupi chodetsa nkhawa, mwina chifukwa cha matenda am'magazi kapena chifukwa chofalitsa mafuta m'mafupa, mwachitsanzo, kukhala ofala kwambiri nthawi izi kupezeka kwa kufalitsa fusariosis, komwe bowa limatha kufikira ziwalo ziwiri kapena zingapo , zikuipiraipira matenda azachipatala.

Mitundu yayikulu ya Fusarium zokhoza kuyambitsa matenda mwa anthu ndi Fusarium solani, Fusarium oxysporum, Fusarium verticillioides ndipo Fusarium proliferatum, yomwe imatha kudziwika kudzera m'mayeso a labotale.

Zizindikiro za matenda mwa Fusarium spp.

Zizindikiro za matenda a Fusarium spp. sizitchulidwazi, popeza zimakhala zofanana ndi zizindikilo za matenda ena obwera chifukwa cha bowa, zimatengera chitetezo chamthupi cha munthu, chifukwa ndi bowa wopezera mwayi, ndipo zimatha kusiyanasiyana kutengera komwe bowa amapezeka mthupi. Zizindikiro zazikulu za fusariosis ndi:

• Malungo;
• Kupweteka kwa minofu;
• Zilonda za khungu, zomwe zimapweteka ndipo zimatha kukhala zilonda zam'mimba ndipo zimawoneka pafupipafupi pa thunthu ndi malekezero;
• Kuchepetsa milingo yazidziwitso;
• Kutupa kwa Corneal;
• Kusintha kwamtundu, makulidwe ndi mawonekedwe a msomali, kuphatikiza pakupezeka kwa mafinya, nthawi zina;
• Matenda opuma, mtima, chiwindi, aimpso kapena amitsempha, kutengera malo abowa.

Matenda ndi Fusarium spp. ndizofala kwambiri kuti zitheke mwa anthu omwe ali ndi matenda am'magazi, neutropenia, omwe adalowetsedwa m'mafupa kapena chemotherapy, omwe agwiritsa ntchito mankhwala opha tizilombo pofuna kuteteza matenda Kandida sp., mwachitsanzo, ndipo ali ndi matenda omwe amalepheretsa chitetezo cha mthupi.

Matenda opatsirana ali bwanji

Matenda ndi Fusarium spp. Zimachitika makamaka kudzera mu kutulutsa mpweya kwa tinthu tomwe timapezeka m'chilengedwe, popeza bowa uyu amapezeka makamaka mu zomera ndi nthaka. Komabe, matenda amatha kukhalanso kudzera pakuthira mwachindunji bowa, nthawi zambiri chifukwa chodulidwa ndi nthambi, mwachitsanzo, zomwe zimayambitsa fungal keratitis.

Fungal keratitis ndi chimodzi mwazizindikiro za matenda a Fusarium spp. ndipo chimafanana ndi kutupa kwa diso komwe kumatha kubweretsa khungu, ndipo ndikofunikira kuti izindikiridwe ndikuchiritsidwa kudzera pakuzika kwaminyemba posachedwa kuti zisawonongeke bowa. Kuphatikiza apo, fungal keratitis mwa Fusarium Zitha kuchitika chifukwa chogwiritsa ntchito magalasi oipitsidwa ndi bowa. Dziwani zambiri za keratitis.

Momwe matendawa amapangidwira

Kuzindikira kwa fusariosis kumapangidwa ndi dokotala wopatsirana wopatsirana pogwiritsa ntchito kuwunika kwa zisonyezo zomwe zikuwonetsedwa, kuwonjezera pazotsatira zoyesedwa za labotale. Chiyeso chomwe chimatsimikizira matenda ndi Fusarium spp. ndikudzipatula kwa bowa m'malo omwe ali ndi kachilomboka, komwe kumatha kukhala khungu, mapapo kapena magazi malinga ndi wodwalayo.

Pambuyo podzipatula komanso pachikhalidwe, kuwonera tinthu tating'onoting'ono kumachitika kuti tiwone bowa womwe umayambitsa matendawa. Ngakhale iyi ndi njira yodziwira yomwe imatsimikizira fusariosis, maluso awa amatenga nthawi, chifukwa zimatenga nthawi kuti bowa ikule mokwanira kuti izitha kuwona pansi pa microscope. Kuphatikiza apo, kudzipatula ndikuwonetsetsa sikuloleza kuzindikira mitundu yomwe imayambitsa matendawa, zomwe zimafunikira kugwiritsa ntchito njira zamagulu kuti zizindikire, zomwe zimafunikanso nthawi.

Njira zamagetsi zitha kugwiritsidwanso ntchito kuzindikira Fusarium sp. Aspergillus sp. Mwachitsanzo, zomwe zingasokoneze matendawa.

Ngakhale kudzipatula ndikudziwika kwa bowa kumafunikira nthawi yochulukirapo, mayesero adawonetsedwa kuti atsimikizire matenda.Kuphatikiza apo, kuwunika kwa histological kumatha kuchitidwa, komwe minofu imapangidwira ndipo, ngati kupezeka kwa bowa kumatha kupezeka, chithandizo cha prophylactic chikadikirira zotsatira za chikhalidwe.

Chithandizo cha Fusariosis

Fusariosis imathandizidwa ndi ma antifungal othandizira omwe ayenera kugwiritsidwa ntchito malinga ndi zomwe adokotala akuti, Amphotericin B ndi Voriconazole ndiye omwe akuwonetsedwa kwambiri. Amphotericin B ndiye mankhwala antifungal omwe amawonetsedwa mu fusariosis yofalitsidwa, komabe mankhwalawa amaphatikizidwa ndi kawopsedwe kambiri ndipo odwala ena samvera chithandizo, ndipo kugwiritsa ntchito Voriconazole ndikulimbikitsidwa.

O Fusarium spp. imatha kulimbana ndi Fluconazole ndi ma antifungals a m'gulu la echinocandin, monga Micafungin ndi Caspofungin, zomwe zimapangitsa kuti mankhwalawa akhale ovuta komanso atha kuphatikizidwa ndi kuchuluka kwa matenda ndi kufa.