Copaxone (glatiramer nthochi)

Zamkati

• Copaxone ndi chiyani?
• Zambiri
• Kuchita bwino
• Copaxone generic
• Zotsatira za Copaxone
• Kodi zotsatira zoyipa za Copaxone zimatenga nthawi yayitali bwanji?
• Zotsatira zoyipa
• Zotsatira zoyipa
• Zotsatira zoyipa
• Postinjection anachita
• Jekeseni wa tsamba la jakisoni kapena zowawa
• Kuwonongeka kwa khungu pamalo obayira jekeseni
• Kupweteka pachifuwa
• Matupi awo sagwirizana
• Kulemera kapena kuwonda
• Matenda okhumudwa
• Momwe mungatengere Copaxone
• Malo opangira jekeseni wa Copaxone
• Malangizo othandizira Copaxone
• Nthawi yoti mutenge
• Mlingo wa Copaxone
• Mitundu ya mankhwala ndi mphamvu
• Mlingo wa MS
• Ndingatani ngati ndaphonya mlingo?
• Mlingo wosowa wa Copaxone 20 mg tsiku lililonse
• Mlingo wa Copaxone 40 mg katatu pamlungu
• Kodi ndiyenera kugwiritsa ntchito mankhwalawa nthawi yayitali?
• Njira zina zopezera Copaxone
• Copaxone vs. Glatopa
• Zosakaniza
• Ntchito
• Mphamvu zamankhwala ndi mawonekedwe
• Kuchita bwino ndi chitetezo
• Mtengo
• Copaxone vs. Tecfidera
• Zosakaniza
• Ntchito
• Mafomu azamankhwala ndi makonzedwe
• Zotsatira zoyipa ndi zoopsa
• Zotsatira zoyipa
• Zotsatira zoyipa
• Kuchita bwino
• Mtengo
• Copaxone ya MS
• Kuchita bwino kwa MS
• Kuchita bwino kwa CIS
• Copaxone ndi ana
• Kutha kwa Copaxone, kusunga, ndi kutaya
• Yosungirako
• Kutaya
• Mafunso wamba pa Copaxone
• Kodi ndidzakhala ndi zizindikilo zobwerera m'mbuyo kapena zotsatirapo zoyipa nditaleka Copaxone?
• Kodi kugwiritsa ntchito Copaxone kumawonjezera chiopsezo changa cha khansa?
• Kodi Copaxone ndi biologic?
• Kodi mungatenge nthawi yayitali bwanji Copaxone?
• Kodi ndingapereke magazi ndikumwa Copaxone?
• Copaxone ndi mimba
• Copaxone ndi kulera
• Copaxone ndi kuyamwitsa
• Copaxone ndi mowa
• Kuyanjana kwa Copaxone
• Momwe Copaxone imagwirira ntchito
• Kodi chimachitika ndi chiyani mu MS?
• Kodi kubwereranso MS ndi chiyani?
• CIS ndi chiyani?
• Kodi Copaxone amachita chiyani?
• Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?
• Mtengo wa Copaxone
• Thandizo lazachuma komanso inshuwaransi
• Mtundu wa generic
• Njira zopewera Copaxone
• Kuledzera kwa Copaxone
• Zoyenera kuchita ngati mwatenga Copaxone wambiri
• Zambiri zamaluso za Copaxone
• Zisonyezero
• Njira yogwirira ntchito
• Pharmacokinetics ndi metabolism
• Zotsutsana
• Yosungirako

Copaxone ndi chiyani?

Copaxone ndi mankhwala omwe amadziwika kuti ndi mankhwala. Amavomerezedwa kuti athetse mitundu ina ya multiple sclerosis (MS) mwa akulu.

Ndi MS, chitetezo chanu chamthupi chimalowerera misempha yanu molakwika. Mitsempha yowonongeka ndiye imakhala ndi vuto lolumikizana ndi ubongo wanu. Vutoli limatha kuyambitsa zizindikilo zosiyanasiyana, monga kufooka kwa minofu ndi kutopa (kusowa mphamvu).

Makamaka, Copaxone itha kugwiritsidwa ntchito pochita izi:

• Matenda opatsirana mwachipatala (CIS). Ndi CIS, muli ndi gawo lazizindikiro zofananira ndi MS zomwe zimatha maola 24. CIS itha kukhala MS kapena ayi.
• Kubwezeretsanso MS (RRMS). Ndi mtundu uwu wa MS, mumakhala ndi nthawi yomwe matenda anu a MS amabwereranso (kuwuka) ndikutsatiridwa ndi nthawi yomwe matenda anu a MS akukhululukidwa (bwino kapena achoka).
• Yogwira MS yachiwiri yopita patsogolo. Ndi mtundu uwu wa MS, vutoli limakulirakulirabe, koma mumakhalabe ndi nthawi yobwereranso. Mukamabwereranso, zizindikiro zanu zimaipiraipira kwakanthawi.

Zambiri

Copaxone imakhala ndi mankhwala osokoneza bongo a glatiramer acetate. Ndi mankhwala osintha matenda a MS. Copaxone imathandizira kuletsa chitetezo cha mthupi chanu kuti chisalimbane ndi mitsempha yanu. Mankhwalawa amatha kuchepetsa kuchuluka kwa MS kubwereranso komwe muli nako ndikuchepetsa kuchepa kwa matenda anu.

Copaxone imabwera ngati yankho lomwe limaperekedwa ndi jakisoni wocheperako (jakisoni pansi pa khungu lanu). Wothandizira zaumoyo wanu adzakuwonetsani inu kapena omwe amakusamalirani momwe mungagwiritsire ntchito mankhwalawa.

Copaxone imabwera muyezo umodzi, ma syringe oyikika kale. Amapezeka mu mphamvu ziwiri: 20 mg ndi 40 mg. Jekeseni wa 20-mg amatengedwa kamodzi tsiku lililonse, pomwe jakisoni wa 40-mg amatengedwa katatu sabata iliyonse osachepera maola 48 padera.

Kuchita bwino

Kuti mumve zambiri zantchito ya Copaxone, onani gawo "Copaxone for MS" pansipa.

Copaxone generic

Copaxone imakhala ndi mankhwala osokoneza bongo a glatiramer acetate. Mitundu yachibadwa ya Copaxone ilipo, kuphatikizapo mankhwala achibadwa otchedwa Glatopa.

Mankhwala achibadwa ndi mankhwala enieni a mankhwala omwe ali ndi dzina lodziwika. Mankhwalawa amawoneka kuti ndi otetezeka komanso ogwira ntchito ngati mankhwala oyamba. Zodzoladzola zimakhala zotsika mtengo poyerekeza ndi mankhwala osokoneza bongo.

Zotsatira za Copaxone

Copaxone imatha kuyambitsa zovuta zochepa kapena zoyipa. Mndandanda wotsatira uli ndi zovuta zina zomwe zingachitike mukamamwa Copaxone. Mndandandawu mulibe zovuta zonse zomwe zingachitike.

Kuti mumve zambiri pazotsatira zoyipa za Copaxone, lankhulani ndi dokotala kapena wamankhwala. Amatha kukupatsirani malangizo amomwe mungathetsere mavuto omwe angakhale ovuta.

Zindikirani: Food and Drug Administration (FDA) imatsata zotsatirapo zamankhwala omwe avomereza. Ngati mungafune kuuza FDA zotsatira zoyipa zomwe mwakhala nazo ndi Copaxone, mutha kutero kudzera ku MedWatch.

Kodi zotsatira zoyipa za Copaxone zimatenga nthawi yayitali bwanji?

Zotsatira zoyipa zomwe mungakhale nazo kuchokera ku Copaxone, komanso kuti zimatenga nthawi yayitali bwanji, zimadalira momwe thupi lanu limachitikira ndi mankhwalawa.

Zovuta zina zimatha kukhala kwakanthawi kochepa. Mwachitsanzo, anthu ena amatchedwa postinjection reaction atalandira jakisoni wa Copaxone. Izi zimatha kuyambitsa zizindikilo monga kutsuka, kupweteka pachifuwa, komanso kuthamanga kwa mtima. Ngati muli ndi postinjection reaction ku Copaxone, zizindikilo zanu zimatha mpaka ola limodzi mutamwa mankhwala anu.

Kumbali inayi, zovuta zina zimatha kukhala zokhalitsa. Mwachitsanzo, anthu ena amawonongeka pakhungu pomwe amalowetsa Copaxone pakhungu lawo. Ndipo nthawi zina, kuwonongeka kwa khungu chifukwa cha jakisoni wa Copaxone kumatha. (Pofuna kuchepetsa ngozi yakuwonongeka kwa khungu, muyenera kusinthasintha malo obayira mukalandira jakisoni wanu wa Copaxone.)

Kuti mudziwe zambiri za zotsatirazi, onani gawo la "Zotsatira zoyipa" pansipa.

Zotsatira zoyipa

Zotsatira zoyipa za Copaxone zitha kuphatikiza:

• malo obayira jekeseni, omwe angayambitse kufiira, kupweteka, kuyabwa, zotupa, kapena kutupa m'mbali mwa jakisoni wanu
• kuchapa
• zotupa pakhungu
• kupuma movutikira
• nkhawa
• nseru ndi kusanza
• kufooka
• matenda, monga chimfine kapena chimfine
• kupweteka kumbuyo kwanu kapena ziwalo zina za thupi lanu
• kupweteka kwa mtima (kumverera ngati mtima wanu ukugunda, kukugwedezeka, kapena kugunda)
• kutuluka thukuta kuposa masiku onse
• kusintha kwa kulemera, kuphatikiza kunenepa kapena kuchepa thupi

Zambiri mwa zotsatirazi zimatha kutha masiku angapo kapena milungu ingapo. Koma ngati akula kwambiri kapena osachokapo, lankhulani ndi dokotala kapena wamankhwala.

Zotsatira zoyipa

Zotsatira zoyipa zochokera ku Copaxone sizofala, koma zimatha kuchitika. Itanani dokotala wanu nthawi yomweyo ngati muli ndi zovuta zina. Koma itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukudwala mwadzidzidzi.

Zotsatira zoyipa, zomwe zafotokozedwa mwatsatanetsatane pansipa mu "Zotsatira zoyipa," ndi izi:

• postinjection reaction (zomwe zimachitika mkati mwathupi mutangolandira jakisoni wa mankhwala)
• kuwonongeka kwa khungu pamalo a jakisoni wanu
• kupweteka pachifuwa
• thupi lawo siligwirizana

Zotsatira zoyipa

Mutha kudabwa kuti zovuta zina zimachitika kangati ndi mankhwalawa. Nazi zina mwazomwe zingayambitse mankhwalawa.

Postinjection anachita

Anthu ena amayankha ku Copaxone atangolandira jakisoni wa mankhwalawa. Chotsatira ichi chimatchedwa postinjection reaction. Zingayambitse zizindikiro kuphatikizapo:

• kuchapa
• kupweteka pachifuwa
• kuthamanga kwa mtima
• kupweteka kwa mtima (kumverera ngati mtima wanu ukugunda, kukugwedezeka, kapena kugunda)
• kuvuta kupuma
• zolimba pakhosi panu
• nkhawa
• urticaria (ming'oma yoyipa)

Zizindikiro za postinjection reaction zimasintha mkati mwa ola limodzi mutalandira jakisoni. Ngati matenda anu atenga nthawi yayitali kuposa izi, kapena ali ovuta, itanani dokotala nthawi yomweyo. Koma ngati zizindikiro zanu zikuwopseza moyo, itanani 911.

Anthu ena amangokhala ndi postinjection reaction atalandira jakisoni woyamba wa Copaxone. Koma anthu ena amatha kuyankha akalandira jakisoni wamankhwala aliwonse. Ndikothekanso kuti muyambe kuchita izi mutalandira jakisoni wa Copaxone m'mbuyomu popanda mavuto.

Ngati mukuda nkhawa kuti mudzalandira mankhwala opatsirana ndi Copaxone, lankhulani ndi dokotala wanu.

Kodi postinjection reaction imakhala yotani?

M'maphunziro azachipatala, pafupifupi 16% ya anthu omwe amatenga Copaxone 20 mg tsiku lililonse amakhala ndi vuto la postinjection. Poyerekeza, 4% ya anthu omwe adatenga placebo (osagwiritsa ntchito mankhwala osokoneza bongo) adachitapo kanthu posankha jakisoni.

Zotsatira za jakisoni wa positi sizinali zofala kwa anthu omwe amatenga Copaxone 40 mg katatu pamlungu. Mwachitsanzo, panthawi yophunzira zachipatala, 2% mwa anthuwa adachitapo kanthu posankha jekeseni. Pakafukufukuyu, palibe amene amatenga placebo anali ndi postinjection reaction.

Jekeseni wa tsamba la jakisoni kapena zowawa

Zotsatira zoyipa kwambiri za Copaxone ndimakhungu omwe amapezeka m'malo opangira jakisoni. Izi zimatha kuyambitsa mabala, kufiira, kutupa, zotupa, kupweteka, kapena kuyabwa.

M'maphunziro azachipatala, zotsatirazi zotsatila za jakisoni zidanenedwa:

• Kufiira. Izi zimachitika mu 22% mpaka 43% ya anthu omwe adatenga Copaxone. Poyerekeza, 2% mpaka 10% ya anthu omwe adatenga placebo (osagwiritsa ntchito mankhwala osokoneza bongo) anali ofiira.
• Ululu. Izi zimachitika mwa anthu 10% mpaka 40% omwe adatenga Copaxone. Poyerekeza, 2% mpaka 20% ya anthu omwe adatenga maloboti anali ndi ululu.
• Kuyabwa. Izi zimachitika mwa anthu 6% mpaka 27% omwe adatenga Copaxone. Poyerekeza, 0% mpaka 4% ya anthu omwe adatenga maloboti anali kuyabwa.
• Ziphuphu. Izi zimachitika mwa anthu 6% mpaka 26% omwe adatenga Copaxone. Poyerekeza, 0% mpaka 6% ya anthu omwe adatenga placebo anali ndi zotupa.
• Kutupa. Izi zimachitika mwa 6% mpaka 19% ya anthu omwe adatenga Copaxone. Poyerekeza, 0% mpaka 4% ya anthu omwe adatenga placebo adatupa.

Pakufufuza, mayendedwe amalo obayira jekeseni anali ofala kwambiri mwa anthu omwe amatenga Copaxone 20 mg tsiku lililonse kuposa momwe amachitira anthu omwe amatenga Copaxone 40 mg katatu pamlungu.

Ngati muli ndi jekeseni wa Copaxone, mayankhowo ayenera kuchepetsedwa m'masiku ochepa. Koma ngati sizili choncho kapena matenda anu akukulira, itanani dokotala wanu.

Kuwonongeka kwa khungu pamalo obayira jekeseni

Nthawi zambiri, jakisoni wa Copaxone amatha kuwononga khungu pamalo obayira. Nthawi zina, kuwonongeka kwa khungu chifukwa cha jakisoni wa Copaxone kumatha.

Zitsanzo za kuwonongeka kwa khungu komwe kumatha kuchitika ndi Copaxone ndi monga:

• Lipoatrophy. Ndi lipoatrophy, mafuta osanjikiza pakhungu lanu awonongeka. Kuwonongeka uku kumatha kuyambitsa maenje okhazikika pakhungu lanu. M'maphunziro azachipatala, lipoatrophy idachitika mwa 2% ya anthu omwe amatenga Copaxone 20 mg tsiku lililonse. Ndipo zidachitika mwa 0,5% ya anthu omwe amatenga Copaxone 40 mg katatu pamlungu. Palibe amene adatenga placebo (wopanda mankhwala osokoneza bongo) anali ndi lipoatrophy.
• Necrosis ya khungu. Ndi khungu la necrosis, khungu lanu limafa. Matendawa amatha kupangitsa khungu lanu kuwoneka lofiirira kapena lakuda. Izi ndi zotsatira zoyipa zomwe zakhala zikudziwika kuyambira pomwe Copaxone idatulutsidwa pamsika. Ndipo sizikudziwika kuti matendawa amapezeka kangati mwa anthu omwe amagwiritsa ntchito Copaxone.

Mutha kuchepetsa chiopsezo chanu cha lipoatrophy ndi khungu necrosis mwa kutsatira mosamalitsa malangizo a omwe amakupatsani za majakisoni a Copaxone. Mwachitsanzo, ndikofunikira kuti musabaye mankhwala anu pamalo omwewo mthupi lanu pamlingo uliwonse. M'malo mwake, muyenera kusinthasintha ma jekeseni anu nthawi iliyonse mukamwa Copaxone.

Ngati mukudandaula za kuwonongeka kwa khungu mukamagwiritsa ntchito Copaxone, lankhulani ndi dokotala wanu.

Kupweteka pachifuwa

Ndikotheka kukhala ndi ululu pachifuwa ngati gawo la postinjection reaction ku Copaxone. Mukakumana ndi postinjection, mumakhala ndi zizindikilo zina, monga kupweteka pachifuwa, mutangomwa Copaxone. (Onani gawo lomwe lili pamwambapa kuti mumve zambiri pazomwe mungachite posankha jekeseni.)

Komabe, anthu ena omwe amatenga Copaxone amamva kupweteka pachifuwa zomwe sizimachitika atangolandira jakisoni wa mankhwalawa. Ndipo kupweteka pachifuwa kutsatira jakisoni wa Copaxone sikuchitika nthawi zonse ndi zizindikilo zina.

M'maphunziro azachipatala, pafupifupi 13% ya anthu omwe amatenga Copaxone 20 mg tsiku lililonse anali ndi kupweteka pachifuwa. Ndipo pafupifupi 2% ya anthu omwe amatenga Copaxone 40 mg katatu pamlungu anali ndi kupweteka pachifuwa. Poyerekeza, kupweteka pachifuwa kunanenedwa mu 1% mpaka 6% ya anthu omwe adatenga placebo (osagwiritsa ntchito mankhwala osokoneza bongo). M'maphunzirowa, zowawa za pachifuwazi zimakhudzana ndi zomwe zimachitika posankha jekeseni. Koma nthawi zambiri, sizinali zokhudzana ndi zomwe zimachitika posankha jekeseni.

Ngati mukumva kupweteka pachifuwa mukamamwa Copaxone, ayenera kuchoka msanga. Komabe, ngati muli ndi zowawa zomwe zimatenga nthawi yayitali kuposa mphindi zochepa kapena zovuta, itanani dokotala wanu molondola. Ndipo ngati ululu wanu ukuwonongedwa, itanani 911.

Matupi awo sagwirizana

Monga momwe zimakhalira ndi mankhwala ambiri, anthu ena amatha kusokonezeka atalandira Copaxone. Koma sizikudziwika kuti izi zimachitika kangati mwa anthu omwe amagwiritsa ntchito mankhwalawa.

Zizindikiro za kuchepa pang'ono zimatha kuphatikiza:

• zotupa pakhungu
• kuyabwa
• Kutentha (kutentha ndi kufiira pakhungu lanu)

Zomwe zimayambitsa matendawa zimakhala zochepa koma ndizotheka. Zizindikiro za kuyanjana kwambiri ndi izi:

• kutupa pansi pa khungu lanu, makamaka m'makope anu, milomo, manja, kapena mapazi
• kutupa lilime, pakamwa, kapena pakhosi
• kuvuta kupuma

Itanani dokotala wanu nthawi yomweyo ngati muli ndi vuto lalikulu la Copaxone. Koma itanani 911 ngati zizindikiro zanu zikuwopseza moyo kapena ngati mukuganiza kuti mukudwala mwadzidzidzi.

Kulemera kapena kuwonda

Anthu ena omwe amatenga Copaxone adapeza kunenepa. M'maphunziro azachipatala, 3% ya anthu omwe adamwa mankhwalawa adayamba kunenepa. Poyerekeza, 1% ya anthu omwe adatenga maloboti (osagwiritsa ntchito mankhwala) adayamba kunenepa.

Komabe, kunenepa kumathanso kukhudzana ndi multiple sclerosis (MS) palokha. Mwachitsanzo, ziwiri mwazizindikiro za MS ndikutopa (kusowa mphamvu) komanso kuyenda movutikira. Ndipo zizindikilo zonsezi zimatha kukupangitsani kuti musamagwire ntchito mopitilira muyeso, zomwe zingayambitse kunenepa.

Ndikofunikanso kuzindikira kuti ma corticosteroids, omwe amagwiritsidwa ntchito kuthandizira kuthana ndi ziwopsezo za MS, amathanso kuyambitsa kunenepa.

Mbali inayi, palinso malipoti ena ochepetsa anthu omwe amagwiritsa ntchito Copaxone. Komabe, malipoti awa anali osowa. Sizikudziwika kuti kuwonda kumachitika kangati mwa anthu omwe amagwiritsa ntchito Copaxone, kapena ngati zoyambitsa zimayambitsidwa ndi Copaxone.

Ngati mukudandaula za kusintha kwa kulemera kwanu mukamamwa Copaxone, lankhulani ndi dokotala wanu. Amatha kukulangizani zamaupangiri azakudya ndi zolimbitsa thupi zokuthandizani kuti muchepetse thupi lomwe lingakhale labwino kwa inu.

Matenda okhumudwa

Anthu ena amatha kukhumudwa akamamwa Copaxone. M'maphunziro, anthu ena omwe amatenga Copaxone akuti ali ndi vuto la kukhumudwa. Komabe, sizikudziwika kuti izi zidachitika kangati, kapena ngati zidachitika ndi Copaxone.

Komabe, kafukufuku waposachedwa apeza kuti Copaxone sawonjezera chiopsezo cha kukhumudwa kwa anthu omwe ali ndi MS. Ndipo kafukufuku wina adawonetsa kuti Copaxone sinawonjezere zizindikiro za kukhumudwa mwa anthu omwe anali kale ndi vutoli.

Ndikofunika kuzindikira kuti kukhumudwa kumakhala kofala mwa anthu omwe ali ndi multiple sclerosis (MS). Mwachitsanzo, kukhumudwa kumachitika pafupifupi 40% mpaka 60% ya anthu omwe ali ndi MS nthawi ina m'moyo wawo.

Ngati mukumva kukhumudwa mukamamwa Copaxone, lankhulani ndi dokotala wanu. Pali njira zambiri zothandizira zomwe zingakuthandizeni kuthana ndi vutoli. Ndipo dokotala wanu angakulimbikitseni njira zomwe zingakuthandizeni.

Kutaya tsitsi (osati zotsatira zoyipa)

Tsitsi silinawoneke mwa anthu omwe adatenga Copaxone panthawi yamaphunziro oyambira azachipatala.

Komabe, kutayika kwa tsitsi ndi gawo limodzi lodziwika la mankhwala osokoneza bongo, * omwe nthawi zina amagwiritsidwa ntchito pochiza multiple sclerosis (MS). Mankhwalawa akuphatikizapo mitoxantrone ndi cyclophosphamide. Koma kumbukirani kuti Copaxone si mankhwala osokoneza bongo.

Ngati mukudandaula za kutayika kwa tsitsi mukamamwa Copaxone, lankhulani ndi dokotala wanu. Amatha kukuthandizani kupeza njira zothetsera zotsatirazi.

Momwe mungatengere Copaxone

Muyenera kumwa Copaxone malinga ndi malangizo a dokotala kapena wothandizira zaumoyo.

Copaxone imatengedwa ndi jakisoni wocheperako (jekeseni pansi pa khungu lanu). Wothandizira zaumoyo wanu akuphunzitsani inu kapena omwe amakusamalirani momwe mungagwiritsire ntchito mankhwalawa. Ndipo mukangoyamba kumene kumwa mankhwala a Copaxone, dokotala kapena namwino wanu adzakuthandizani kukupatsani jakisoni woyamba.

Copaxone imabwera ngati yankho mkati mwa mlingo umodzi, ma syringe omwe ali ndi singano. Ngati simuli omasuka kugwiritsa ntchito ma syringe, funsani adotolo za chipangizo china chapadera, chotchedwa galimotojct 2 ya syringe yagalasi.

Kugwiritsa ntchito galimotojct 2, muika syringe ya Copaxone yomwe ili mkati mwa chipangizocho. Pulogalamu ya galimotojct 2 amabisa singano ya syringe ndikukulolani kuti mulowetse mankhwalawo podina batani, m'malo mokankhira pansi pa syringe's plunger.

Malangizo obaya jekeseni wa Copaxone amaperekedwa m'kapepala komwe kamachokera ku pharmacy yanu ndi Copaxone.

Kuphatikiza apo, wopanga mankhwalawa amaperekanso chitsogozo cha jakisoni ndi kanema wophunzitsira pang'onopang'ono. Izi zimafotokozera zambiri zamomwe mungagwiritsire ntchito jakisoni wa Copaxone ndi galimotojct 2. Ndipo amafotokozera makonda akuya a jakisoni omwe muyenera kusankha mukamagwiritsa ntchito galimotojct 2.

Malo opangira jekeseni wa Copaxone

Mutha kubaya Copaxone pansi pa khungu la mbali zotsatirazi za thupi lanu:

• mimba (mimba) yanu, ngati mumapewa kubayira malo omwe ali mkati mwa mainchesi awiri a batani lanu
• kutsogolo kwa ntchafu zanu, ngati mulowetsa m'dera lomwe lili pafupifupi mainchesi awiri pamwamba pa bondo lanu ndi mainchesi awiri pansi pa kubuula kwanu
• kumbuyo kwa m'chiuno mwanu mchiuno mwanu
• kumbuyo kwa mikono yanu yakumtunda

Lankhulani ndi dokotala wanu za malo omwe ali jekeseniwa ndi abwino kwa inu. Kumbukirani kuti nthawi iliyonse mukabaya mlingo wa Copaxone, muyenera kusinthasintha ma jekeseni omwe mumagwiritsa ntchito. Musagwiritse ntchito malo omwewo opangira jakisoni kamodzi pa sabata.

Ndikofunika kusunga malo obayira omwe mumagwiritsa ntchito mlingo uliwonse wa Copaxone. M'malo mwake, pali pulogalamu ya Copaxone tracker yomwe imapezeka patsamba laopanga zomwe zingakuthandizeni kuchita izi.

Malangizo othandizira Copaxone

Mukamagwiritsa ntchito Copaxone, kumbukirani malangizo awa:

• Chotsani Copaxone mufiriji pafupifupi mphindi 20 musanakonze jakisoni wanu. Izi zimapatsa mankhwalawa nthawi yotentha, zomwe zimapangitsa jekeseni kukhala yabwino kwa inu.
• Majekeseni a Copaxone amangoperekedwa pansi pa khungu lanu. Osalowetsa mankhwalawa mu umodzi mwamitsempha kapena minofu yanu.
• Osalowetsa Copaxone kumadera akhungu lanu ofiira, otupa, otupa, ofiira, kapena opindika. Ndipo pewani kupereka jakisoni m'malo akhungu okhala ndi zikwangwani, zotambasula, kapena ma tattoo.
• Osapaka kapena kusisita tsamba lanu lopangira Copaxone kwa maola osachepera 24 mutabayitsa mankhwala.

Nthawi yoti mutenge

Mukatenga Copaxone zimatengera mphamvu ya mankhwala omwe mukugwiritsa ntchito. Ndondomeko za Mlingo wa Copaxone ndi izi:

• Copaxone 20 mg. Ngati mukugwiritsa ntchito mphamvuzi, mudzabaya mankhwala kamodzi patsiku, nthawi yomweyo tsiku lililonse. Zilibe kanthu kuti mumasankha nthawi yanji, bola ngati mukugwirizana tsiku lililonse.
• Copaxone 40 mg. Ngati mukugwiritsa ntchito mphamvuzi, mudzabaya mankhwalawo katatu pamlungu. Mwachitsanzo, mutha kupanga jakisoni wanu Lolemba, Lachitatu, ndi Lachisanu. Onetsetsani kuti jakisoni akutengedwa osachepera maola 48 padera.

Pofuna kuthandizira kuti musaphonye mlingo, yesani kukhazikitsa chikumbutso pafoni yanu. Zikumbutso zitha kukhazikitsidwa mu pulogalamu ya Copaxone tracker.

Mlingo wa Copaxone

Chidziwitso chotsatirachi chimalongosola miyezo yomwe amagwiritsidwa ntchito kwambiri kapena amalimbikitsidwa. Komabe, onetsetsani kuti mwatenga mlingo womwe dokotala akukulemberani. Dokotala wanu adzazindikira mlingo woyenera kuti mukwaniritse zosowa zanu.

Mitundu ya mankhwala ndi mphamvu

Copaxone imabwera ngati mankhwala amodzi. Amapezeka mu mphamvu ziwiri: 20 mg ndi 40 mg.

Mlingo wa MS

Copaxone ili ndi mankhwala otsatirawa a multiple sclerosis (MS):

• 20 mg yotengedwa kamodzi patsiku
• 40 mg amatengedwa katatu pamlungu

Dokotala wanu akhoza kukulemberani ena mwa ndandanda za mlingowu, kutengera kuti ndi iti yomwe ingakuthandizeni kwambiri.

Ndingatani ngati ndaphonya mlingo?

Zomwe muyenera kuchita mukaphonya mlingo wa Copaxone zimatengera mulingo wa mankhwala omwe mumamwa. Pansipa, tifotokoza zomwe tingachite pa mlingo uliwonse woyenera.

Muthanso kuitanitsa ofesi ya dokotala mukaphonya mlingo wa Copaxone ndipo simukudziwa choti muchite. Dokotala wanu kapena ogwira ntchito zachipatala angakulimbikitseni pamene muyenera kumwa mankhwala anu.

Ndipo kuti mutsimikizire kuti musaphonye mlingo, yesetsani kukhazikitsa chikumbutso pafoni yanu, kapena mugwiritse ntchito pulogalamu ya Copaxone tracker.

Mlingo wosowa wa Copaxone 20 mg tsiku lililonse

Ngati mumamwa Copaxone 20 mg tsiku lililonse, tengani mlingo womwe mwaphonya mukangokumbukira. Koma ngati ili pafupi ndi mlingo wanu wotsatira kuposa momwe mungapangire mlingo womwe mwaphonya, tulukani mlingo womwe mwaphonyawo ndikupitilizabe ndi dosing yanu yanthawi zonse. Musatengere mlingo umodzi palimodzi kuti mupange mlingo wosowa.

Mlingo wa Copaxone 40 mg katatu pamlungu

Ngati mumamwa Copaxone 40 mg ndikusowa mulingo, imwani tsiku lotsatira nthawi yanu. Kenako tengani mlingo wanu wotsatira masiku 2 pambuyo pake munthawi yanu. Yesetsani kubwerera ku ndandanda yanu sabata yotsatira. Koma kumbukirani, payenera kukhala maola osachepera 48 pakati pa mlingo wanu.

Mwachitsanzo, ngati mumamwa Copaxone Lolemba, Lachitatu, ndi Lachisanu, koma mwaphonya mlingo wanu wa Lolemba, tengani mlingo womwe mwaphonya Lachiwiri. Kenako tengani Mlingo wanu wotsala mlunguwo Lachinayi ndi Loweruka. Sabata yotsatira, mutha kubwerera ku ndandanda yanu.

Kodi ndiyenera kugwiritsa ntchito mankhwalawa nthawi yayitali?

Copaxone amayenera kugwiritsidwa ntchito ngati chithandizo chanthawi yayitali. Ngati inu ndi dokotala mukuwona kuti Copaxone ndiyotetezeka komanso yothandiza kwa inu, mutha kuitenga nthawi yayitali.

Njira zina zopezera Copaxone

Mankhwala ena alipo omwe angachiritse multiple sclerosis (MS), komanso matenda opatsirana pogonana (CIS). (CIS ndi vuto lomwe limayambitsa zizindikiro ngati za MS.)

Mankhwala ena akhoza kukhala abwino kwa inu kuposa ena. Ngati mukufuna kupeza njira ina kuposa Copaxone, lankhulani ndi dokotala wanu. Amatha kukuwuzani zamankhwala ena omwe atha kukuthandizani.

Zitsanzo za mankhwala ena omwe angagwiritsidwe ntchito pochiza MS kapena CIS ndi awa:

• corticosteroids, omwe amagwiritsidwa ntchito pochiza matenda a MS kapena zigawo za CIS, monga:
  • methylprednisolone (Medrol)
  • prednisone (Rayos)
• Mankhwala osintha matenda omwe amatengedwa pakamwa, monga:
  • dimethyl fumarate (Tecfidera)
  • diroximel fumarate (Kuchuluka)
  • fingolimod (Gilenya)
  • siponimod (Mayzent)
  • teriflunomide (Aubagio)
• Mankhwala osinthira matenda omwe amadzipiritsa, monga:
  • glatiramer nthochi (Glatopa)
  • interferon beta-1a (Avonex, Rebif)
  • interferon beta-1b (Betaseron, Extavia)
  • pegylated interferon beta-1a (Plegridy)
• Mankhwala osinthira matenda omwe amaperekedwa kudzera m'mitsempha (jekeseni mumitsempha yanu), monga:
  • alemtuzumab (Lemtrada)
  • natalizumab (Tysabri)
  • ocrelizumab (Ocrevus)

Copaxone vs. Glatopa

Mutha kudabwa momwe Copaxone ikufananirana ndi mankhwala ena omwe amaperekedwa kuti agwiritse ntchito chimodzimodzi. Apa tikuwona momwe Copaxone ndi Glatopa alili ofanana komanso osiyana.

Zosakaniza

Copaxone ndi Glatopa onse ali ndi mankhwala omwewo: glatiramer acetate.

Komabe, ngakhale Copaxone ndi mankhwala odziwika ndi dzina, Glatopa ndi Copaxone wamba. Mankhwala achibadwa ndi mankhwala enieni a mankhwala omwe ali ndi dzina lodziwika.

Ntchito

Copaxone ndi Glatopa onse amavomerezedwa kuti athetse mitundu ina ya multiple sclerosis (MS) mwa akulu.

Makamaka, Copaxone ndi Glatopa zitha kugwiritsidwa ntchito pochita izi:

• matenda opatsirana (CIS)
• Kubwezeretsanso MS (RRMS)
• MS yachiwiri yogwira ntchito (SPMS)

Copaxone ndi Glatopa onse amatchedwa mankhwala osintha matenda. Amagwira ntchito pothandiza kuyimitsa chitetezo chamthupi chanu kuti chisamakhudzitse mitsempha yanu. Mankhwalawa amatha kuchepetsa kuchuluka kwa MS komwe mumabwereranso komanso amachepetsa matenda anu kukulira.

Mphamvu zamankhwala ndi mawonekedwe

Copaxone ndi Glatopa onse amabwera ngati zothetsera vuto limodzi. Zonsezi zimaperekedwa ndi jakisoni wocheperako (jakisoni pansi pa khungu lanu). Kutengera mphamvu yamankhwala omwe dokotala akukulemberani, mumamwa mankhwala aliwonse kamodzi kapena kamodzi pa sabata.

Wothandizira zaumoyo wanu akuphunzitsani kapena kukusamalirani momwe mungabayire mankhwalawa.

Kuchita bwino ndi chitetezo

Dipatimenti ya Food and Drug Administration (FDA) imawona kuti ma genics ndi otetezeka komanso ogwira ntchito monganso mankhwala oyamba aja. Izi zikutanthauza kuti Glatopa amawerengedwa kuti ndi othandiza pochiza MS ndi CIS monga Copaxone. Zimatanthauzanso kuti Copaxone ndi Glatopa zonse zimatha kuyambitsa zovuta zomwezo.

Kuti mudziwe za zovuta zoyipa komanso zoyipa za Copaxone, onani gawo la "zoyipa za Copaxone" pamwambapa.

Mtengo

Copaxone ndi dzina lodziwika bwino, pomwe Glatopa ndi Copaxone. Mankhwala omwe amadziwika ndi dzina lawo nthawi zambiri amawononga ndalama zambiri kuposa omwe amadzipangira okha.

Malinga ndi kuyerekezera kwa GoodRx.com, Glatopa amawononga ndalama zochepa kwambiri kuposa mtengo wa Copaxone. Koma mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, malo omwe muli, komanso mankhwala omwe mumagwiritsa ntchito.

Copaxone vs. Tecfidera

Mutha kudabwa momwe Copaxone ikufananirana ndi mankhwala ena omwe amaperekedwa kuti agwiritse ntchito chimodzimodzi. Apa tikuwona momwe Copaxone ndi Tecfidera alili ofanana komanso osiyana.

Zosakaniza

Copaxone imakhala ndi glatiramer acetate, pomwe Tecfidera imakhala ndi dimethyl fumarate.

Ntchito

Copaxone ndi Tecfidera onse amavomerezedwa kuti athetse mitundu ina ya multiple sclerosis (MS) mwa akulu.

Makamaka, Copaxone ndi Tecfidera zitha kugwiritsidwa ntchito pochita izi:

• matenda opatsirana (CIS)
• Kubwezeretsanso MS (RRMS)
• MS yachiwiri yogwira ntchito (SPMS)

Copaxone ndi Tecfidera onse amatchedwa mankhwala osintha matenda. Amagwira ntchito pothandiza kuyimitsa chitetezo chamthupi chanu kuti chisamakhudzitse mitsempha yanu. Mankhwalawa amatha kuchepetsa kuchuluka kwa MS komwe mumabwereranso komanso amachepetsa matenda anu kukulira.

Mafomu azamankhwala ndi makonzedwe

Copaxone imabwera ngati yankho mkati mwa mankhwala amodzi. Amatengedwa ndi jakisoni wocheperako (jakisoni pansi pa khungu lanu). Kutengera ndi mphamvu ya mankhwala omwe dokotala amakupatsani, amatha kumwa kamodzi kapena tsiku limodzi kapena katatu pamlungu. Wothandizira zaumoyo wanu akuphunzitsani inu kapena omwe amakusamalirani momwe mungagwiritsire ntchito mankhwalawa.

Tecfidera, kumbali inayo, imabwera ngati makapisozi omwe amatengedwa pakamwa. Zimatengedwa kawiri tsiku lililonse.

Zotsatira zoyipa ndi zoopsa

Copaxone ndi Tecfidera onse ali ndi mankhwala osintha matenda. Komabe, mankhwalawa amagwira ntchito m'njira zosiyanasiyana mthupi lanu. Copaxone ndi Tecfidera zimatha kuyambitsa zovuta zina zofanana. M'munsimu muli zitsanzo za zotsatirazi.

Zotsatira zoyipa

Mndandandawu uli ndi zovuta khumi zoyipa kwambiri zomwe zimatha kuchitika ndi Copaxone, ndi Tecfidera, kapena ndi Copaxone ndi Tecfidera (akatenga payekha).

• Zitha kuchitika ndi Copaxone:
  • zochita za jakisoni, zomwe zingayambitse kufiira, kupweteka, kuyabwa, zotupa, kapena kutupa m'dera la jakisoni wanu
  • kupuma movutikira
  • nkhawa
  • kufooka
  • matenda, monga chimfine ndi chimfine
  • kupweteka kumbuyo kwanu kapena ziwalo zina za thupi lanu
  • kupweteka kwa mtima (kumverera ngati mtima wanu ukugunda, kukugwedezeka, kapena kugunda)
  • kutuluka thukuta kuposa masiku onse
  • kusintha kwa kulemera, kuphatikiza kunenepa kapena kuchepa thupi
• Zitha kuchitika ndi Tecfidera:
  • kupweteka m'mimba (m'mimba)
  • kutsegula m'mimba
  • kudzimbidwa
• Zitha kuchitika ndi Copaxone ndi Tecfidera:
  • kuchapa
  • nseru ndi kusanza
  • zotupa pakhungu

Zotsatira zoyipa

Mndandandawu muli zitsanzo za zovuta zoyipa zomwe zingachitike ndi Copaxone, ndi Tecfidera, kapena ndi mankhwala onsewa (akamwedwa payekhapayekha).

• Zitha kuchitika ndi Copaxone:
  • post injection reaction (zomwe zimachitika mkati mwa thupi lanu mutangolandira jakisoni wa mankhwala)
  • kupweteka pachifuwa
  • kuwonongeka kwa khungu pamalo a jakisoni wanu
• Zitha kuchitika ndi Tecfidera:
  • lymphopenia (kuchepa kwa maselo oyera amwazi otchedwa ma lymphocyte)
  • kupita patsogolo kwa leukoencephalopathy (PML), komwe kumayambitsa matenda opha ubongo wanu
  • Matenda ena akulu, monga shingles (matenda omwe amayamba chifukwa cha herpes zoster virus)
  • kuwonongeka kwa chiwindi
• Zitha kuchitika ndi Copaxone ndi Tecfidera:
  • kwambiri thupi lawo siligwirizana

Kuchita bwino

Copaxone ndi Tecfidera onse amavomerezedwa kuti athetse mitundu ina ya MS komanso CIS. Mankhwalawa sanafanane mwachindunji m'maphunziro azachipatala. Koma maphunziro osiyana apeza kuti Copaxone ndi Tecfidera ndizothandiza kuthana ndi izi.

Kafukufuku wina adapeza kuti Tecfidera inali yothandiza kwambiri kuposa Copaxone pochepetsa kuchuluka kwa MS kubwereranso ndikuchepetsa kukulira kwaumalema komwe kumayambitsidwa ndi MS.

Kuphatikiza apo, kafukufuku wina wapeza kuti Tecfidera imakhala yothandiza kwambiri kuposa Copaxone pochepetsa kuchuluka kwa MS kubwerera. Komabe, kafukufukuyu adapeza kuti mankhwalawa anali othandiza mofananamo pakuchepetsa kuchepa kwaumphawi komwe kumayambitsidwa ndi MS.

Ngati mukufuna kumwa imodzi mwa mankhwalawa ku MS, lankhulani ndi dokotala wanu. Angakulimbikitseni mankhwala omwe angakhale abwino kwa inu.

Mtengo

Copaxone ndi Tecfidera onse ndi mankhwala osokoneza bongo. Copaxone imapezekanso mu mawonekedwe achibadwa. Pakadali pano palibe mitundu ya Tecfidera yomwe ilipo. Mankhwala omwe ali ndi dzina nthawi zambiri amawononga ndalama zambiri kuposa ma generic.

Malinga ndi kuyerekezera kwa WellRx.com, Tecfidera imawononga ndalama zambiri kuposa Copaxone. Koma mtengo weniweni womwe mudzalipire mankhwalawa umadalira dongosolo lanu la inshuwaransi, malo omwe muli, komanso mankhwala omwe mumagwiritsa ntchito.

Copaxone ya MS

Food and Drug Administration (FDA) imavomereza mankhwala akuchipatala monga Copaxone kuti athetse mavuto ena. Copaxone itha kugwiritsidwanso ntchito polemba zina pazinthu zina. Kugwiritsa ntchito mankhwala osokoneza bongo ndi pamene mankhwala omwe amavomerezedwa kuti athetse vuto limodzi amagwiritsidwa ntchito kuthana ndi vuto lina.

Copaxone ndivomerezedwa ndi FDA kuti athetse mitundu yobwerezabwereza ya multiple sclerosis (MS) mwa akulu. Mankhwalawa amavomerezedwanso kuti athetse matendawa (CIS) mwa akulu. (CIS ndi vuto lomwe limayambitsa zizindikiro ngati za MS.)

Makamaka, Copaxone itha kugwiritsidwa ntchito pochita izi:

• CIS. Ndi CIS, muli ndi gawo lazizindikiro zofananira ndi MS zomwe zimatha maola 24. CIS itha kukhala MS kapena ayi.
• Kubwezeretsanso MS (RRMS). Ndi mtundu uwu wa MS, mumakhala ndi nthawi yomwe matenda anu a MS amabwereranso (kuwuka) ndikutsatiridwa ndi nthawi yomwe matenda anu a MS akukhululukidwa (bwino kapena achoka).
• Yogwira MS yachiwiri yopita patsogolo (SPMS). Ndi mtundu uwu wa MS, vuto lanu limakulirakulirabe, koma mumakhalabe ndi nthawi yobwereranso. Mukamabwereranso, zizindikiro zanu zimaipiraipira kwakanthawi.

Ndi MS, chitetezo chanu chamthupi chimalowerera misempha yanu molakwika. Mitsempha yowonongeka ndiye imakhala ndi vuto lolumikizana ndi ubongo wanu. Vutoli limatha kuyambitsa zizindikilo zosiyanasiyana, kutengera mitsempha yomwe yawonongeka.

Ndi mitundu yobwerezabwereza ya MS, muli ndi magawo owonongeka kwamitsempha omwe amayambitsa zizindikiro zatsopano za MS. Kapena mutha kukhala ndi nthawi yomwe matenda anu a MS amabwerera kapena kuwonjezeka atatha kusintha.

Copaxone ndi mankhwala osintha matenda. Zimagwira ntchito pochiza MS ndi CIS pothandizira kuyimitsa chitetezo chamthupi chanu kuti chisalimbane ndi mitsempha yanu. Pochita izi, mankhwalawa amachepetsa kuchuluka kwa MS komwe mumabwereranso komanso amachepetsa kukula kwa matenda anu.

Kuchita bwino kwa MS

M'maphunziro angapo azachipatala, Copaxone inali yothandiza pochiza mitundu yobwezeretsanso ya MS. Makamaka, Copaxone idachepetsa kuchuluka kwa MS kubwereranso komwe anthu anali nako. Ndipo mankhwalawa adachepetsa kuchuluka kwa zotupa zamaubongo (madera owonongeka kwa mitsempha) omwe anthu anali nawo matendawa. Copaxone inachepetsanso MS kuti iwonongeke mwa anthu omwe amagwiritsa ntchito mankhwalawa.

Mwachitsanzo, maphunziro awiri adayang'ana momwe kugwiritsa ntchito Copaxone 20 mg tsiku lililonse kwa anthu omwe ali ndi MS. Kwa zaka 2 chithandizo:

• Anthu omwe adatenga Copaxone anali ndi 0.6 mpaka 1.19 MS omwe amabwereranso. Poyerekeza, anthu omwe adatenga placebo (osagwiritsa ntchito mankhwala osokoneza bongo) anali ndi 1,68 mpaka 2.4 MS obwereranso.
• 34% mpaka 56% ya anthu omwe adatenga Copaxone sanabwererenso ku MS. Poyerekeza, 27% mpaka 28% ya anthu omwe adatenga placebo sanabwererenso ku MS.

Kuphatikiza apo, kafukufuku wina adawona momwe kugwiritsa ntchito Copaxone 20 mg tsiku lililonse pakukula kwa zotupa zina zamaubongo. Zilondazi, zomwe zimawonetsa madera otupa muubongo, zimadziwika ndi sikani za MRI. Pa miyezi 9 ya chithandizo:

• theka la anthu omwe adatenga Copaxone adapanga zilonda zatsopano zosachepera 11
• theka la anthu omwe adatenga maloboti adayamba zilonda zatsopano zosachepera 17

Kafukufuku wina adawona momwe kugwiritsa ntchito Copaxone 40 mg katatu pamlungu mwa anthu omwe ali ndi MS. Oposa chaka chimodzi chothandizidwa, poyerekeza ndi anthu omwe amagwiritsa ntchito placebo, anthu omwe amagwiritsa ntchito Copaxone anali:

• 34% chiwopsezo chochepa cha MS kubwerera
• Chiwopsezo chotsika cha 45% cha zotupa zamaubongo zomwe zimawonetsa malo otupa muubongo wawo
• 35% chiwopsezo chotsika cha zotupa zatsopano kapena zomwe zikukula zomwe zimawonetsa malo owonongeka muubongo wawo

Kuchita bwino kwa CIS

Kafukufuku wamankhwala adayang'ana chithandizo cha Copaxone mwa anthu omwe ali ndi CIS. Pakafukufukuyu, Copaxone idachepetsa chiopsezo cha anthu kukhala ndi gawo lachiwiri lazizindikiro zonga za MS.

Pazaka zopitilira zitatu za chithandizo, anthu omwe amamwa Copaxone 20 mg tsiku lililonse anali ocheperako ndi 45% kuti akhale ndi gawo lachiwiri la zofananira za MS kuposa anthu omwe adatenga malowa.

Copaxone ndi ana

Copaxone sivomerezedwa kuti igwiritsidwe ntchito kwa ana azaka 17 kapena kupitirira apo. Komabe, mankhwalawa nthawi zina amagwiritsidwa ntchito pochiza MS kwa ana. (Ndi kugwiritsa ntchito zilembo, mankhwala omwe amavomerezedwa pazinthu zina amagwiritsidwa ntchito pazinthu zina.)

Kafukufuku wina wasonyeza kuti glatiramer (mankhwala omwe ali ku Copaxone) amatha kuchepetsa kuchuluka kwa MS kubwerera kwa ana. Kafukufukuyu adawonetsanso kuti mankhwalawa adachepetsa kukulirakulira kwaumphawi komwe kumayambitsidwa ndi MS. Kuphatikiza apo, International Pediatric Multiple Sclerosis Study Group ikulimbikitsa kugwiritsa ntchito Copaxone ngati imodzi mwanjira zoyambirira zothandizira ana omwe ali ndi MS.

Ngati muli ndi mafunso okhudza kugwiritsa ntchito Copaxone kuchiza MS mwa mwana, lankhulani ndi dokotala wanu.

Kutha kwa Copaxone, kusunga, ndi kutaya

Mukalandira Copaxone ku pharmacy yanu, tsiku lomaliza la mankhwalawo lidzasindikizidwa m'bokosi la ma syringe, komanso ma syringe okha. Tsiku lothera ntchito limatsimikizira kuti mankhwalawa ndi othandiza kugwiritsa ntchito munthawi inayake.

Maganizo apano a Food and Drug Administration (FDA) ndikupewa kugwiritsa ntchito mankhwala omwe atha ntchito. Ngati mwagwiritsa ntchito mankhwala omwe sanadutse tsiku lomaliza, lankhulani ndi wamankhwala wanu ngati mungakwanitse kuugwiritsabe ntchito.

Yosungirako

Kutalika kwa nthawi yayitali kumadalira mankhwala, kuphatikiza momwe mungasungire mankhwalawo.

Masirinji okhathamira a Copaxone amayenera kusungidwa m'firiji kutentha kwa 36 ° F mpaka 46 ° F (2 ° C mpaka 8 ° C). Osamaunditsa ma syringe a Copaxone. Ngati syringe yauma, musagwiritse ntchito. M'malo mwake, tayani syringe mu chidebe chakuthwa.

Ngati simungathe kuyika firiji Copaxone, monga paulendo, mutha kusunga mankhwalawo kutentha kwapakati (59 ° F mpaka 86 ° F / 15 ° C mpaka 30 ° C). Komabe, mutha kusunga Copaxone kutentha kwapakati pa mwezi umodzi. Ndipo pamene mankhwalawa akusungidwa kunja kwa firiji, onetsetsani kuti kutentha sikukwera pamwamba pa 86 ° F (30 ° C).

Kaya mukusunga Copaxone mufiriji kapena kutentha kwapakati, muyenera kusunga ma syringe m'matumba awo amkati, mkati mwa katoni yoyamba. Kuchita izi kudzateteza mankhwala ku kuwala.

Kutaya

Mukangogwiritsa ntchito jakisoni, singano, kapena autoinjector, ikani mu chidebe chovomerezeka chovomerezeka ndi FDA. Izi zimathandiza kupewa ena, kuphatikiza ana ndi ziweto, kumwa mankhwalawo mwangozi kapena kudzivulaza ndi singano. Mutha kugula chidebe chakuthwa pa intaneti, kapena kufunsa dokotala, wamankhwala, kapena kampani ya inshuwaransi yazaumoyo komwe mungapeze.

Nkhaniyi imapereka malangizo othandiza pothana ndi mankhwala. Muthanso kufunsa wamankhwala wanu kuti mumve momwe mungathere mankhwala anu.

Mafunso wamba pa Copaxone

Nawa mayankho pamafunso omwe amafunsidwa kawirikawiri za Copaxone.

Kodi ndidzakhala ndi zizindikilo zobwerera m'mbuyo kapena zotsatirapo zoyipa nditaleka Copaxone?

Ayi, ndizokayikitsa. Zizindikiro zobwerera m'mbuyo ndi zovuta zomwe zingachitike mukasiya kumwa mankhwala omwe thupi lanu limadalira. (Ndikudalira, thupi lanu limafunikira mankhwalawa kuti mumve bwino.)

Kuyimitsa Copaxone sikudziwika chifukwa choyambitsa matendawa. Chifukwa cha izi, simuyenera kusiya kumwa mankhwalawa pang'onopang'ono, monga momwe mumachitira ndi mankhwala ena omwe amatha kuyambitsa matendawa.

Komabe, kumbukirani kuti kuyimitsa Copaxone kungayambitse matenda anu a sclerosis (MS) kuti abwerere kapena kukulira.

Ngati muli ndi mafunso okhudza kuletsa Copaxone, kambiranani ndi dokotala wanu. Amatha kukambirana nanu za kuopsa ndi zabwino zosiya mankhwalawa.

Kodi kugwiritsa ntchito Copaxone kumawonjezera chiopsezo changa cha khansa?

Ayi. Pakadali pano akuganiza kuti palibe chiopsezo chowonjezeka cha khansa pogwiritsa ntchito Copaxone. Ngakhale panali malipoti ena a khansa mwa anthu omwe amamwa mankhwalawa atatulutsidwa pamsika, malipotiwa anali osowa. Ndipo chiopsezo chowonjezeka cha khansa sichinagwirizane mwachindunji ndi kugwiritsa ntchito Copaxone.

Komabe, mankhwala ena omwe amagwiritsidwa ntchito pochiza multiple sclerosis (MS), monga omwe amayambitsa matenda opatsirana pogonana, amatha kuonjezera khansa. Zitsanzo za mankhwalawa ndi monga alemtuzumab (Lemtrada) ndi mitoxantrone.

Nthawi zambiri, chitetezo chamthupi chanu chimapha majeremusi, komanso maselo amthupi lanu omwe siabwino kapena sakugwira ntchito bwino. Izi zimakuthandizani kukutetezani kuti musadwale khansa komanso matenda. Koma ndi chitetezo cha mthupi, chitetezo chanu cha mthupi chimaponderezedwa (kufooka) ndipo sichigwira ntchito moyenera. Ngati chitetezo chanu cha mthupi chitaponderezedwa, muli pachiwopsezo chachikulu chotenga khansa ndi matenda ena.

Copaxone imapangitsa kuti magawo ena amthupi lanu asamagwire ntchito mopitilira muyeso. Komabe, Copaxone amatchedwa immunomodulator, osati immunosuppressant. Izi ndichifukwa Copaxone amasintha momwe chitetezo chamthupi chimagwirira ntchito, m'malo mopondereza chitetezo chanu.

Ngati muli ndi mafunso okhudza kuopsa kwa chithandizo cha Copaxone, lankhulani ndi dokotala wanu.

Kodi Copaxone ndi biologic?

Ayi, Copaxone si biologic. Biologics ndi mankhwala omwe amapangidwa kuchokera m'maselo amoyo. Copaxone imapangidwa ndi mankhwala.

Zina mwa njira zosinthira matenda zomwe zimagwiritsidwa ntchito pochiza ma sclerosis (MS) ndizambiri zamoyo, koma Copaxone siimodzi mwazomwezi. Zitsanzo za biologics zomwe zimagwiritsidwa ntchito pochiza MS zimaphatikizapo alemtuzumab (Lemtrada), natalizumab (Tysabri), ndi ocrelizumab (Ocrevus).

Kuti mumve zambiri za momwe Copaxone imagwirira ntchito ku MS, onani gawo "Momwe Copaxone imagwirira ntchito" pansipa.

Kodi mungatenge nthawi yayitali bwanji Copaxone?

Copaxone amayenera kugwiritsidwa ntchito ngati chithandizo chanthawi yayitali. Mwambiri, mutha kupitiliza kuzigwiritsa ntchito malinga ngati ikupitilizabe kukhala yotetezeka kwa inu.

Koma ngati mukukhala ndi zovuta zina kapena zoyipa, kapena mankhwalawo samayang'anira matenda anu mokwanira, mungafunikire kusinthana ndi mankhwala ena. Zikatero, dokotala wanu angakupatseni chithandizo china.

Ngati muli ndi mafunso okhudza kutalika kwa nthawi yomwe muyenera kumwa Copaxone, lankhulani ndi dokotala wanu.

Kodi ndingapereke magazi ndikumwa Copaxone?

Inde. Malinga ndi American Red Cross, kumwa Copaxone sikuyenera kukulepheretsani kupereka magazi. Komanso ndibwino kupereka magazi ngati muli ndi multiple sclerosis (MS), bola ngati matenda anu akuyendetsedwa bwino ndipo muli ndi thanzi labwino.

Ngati muli ndi mafunso onena ngati zili bwino kuti mupereke magazi, lankhulani ndi dokotala wanu. Kapena mutha kulumikizana ndi American Red Cross pochezera tsamba lawo.

Copaxone ndi mimba

Copaxone sinaphunzire mwa amayi apakati. Chifukwa chake sichidziwika ngati mankhwalawa ndi abwino kumwa panthawi yapakati.

Amayi ena adatenga Copaxone ali ndi pakati. Koma palibe chidziwitso chokwanira chonena ngati mankhwalawa amachulukitsa chiwopsezo cha kupunduka kwa kubadwa kapena kupita padera.

Kafukufuku wazinyama adachitidwa mwa akazi apakati omwe adapatsidwa Copaxone. Ndipo maphunzirowa sanawonetse vuto lililonse kwa fetus pomwe mankhwalawo amagwiritsidwa ntchito. Koma kumbukirani kuti kafukufuku wopangidwa ndi nyama samaneneratu nthawi zonse zomwe zidzachitike mwa anthu.

Ngati muli ndi pakati kapena mutha kutenga pakati, lankhulani ndi dokotala wanu ngati Copaxone ili yoyenera kwa inu. Ndipo ngati mukumwa kale Copaxone ndipo mutakhala ndi pakati, onetsetsani kuti mwamuyimbira dokotala nthawi yomweyo.

Copaxone ndi kulera

Sizikudziwika ngati Copaxone ndiyabwino kutenga nthawi yapakati. Ngati mukugonana ndipo inu kapena mnzanu mutha kutenga pakati, lankhulani ndi adotolo za zosowa zanu zakulera mukamagwiritsa ntchito Copaxone.

Copaxone ndi kuyamwitsa

Sizikudziwika ngati Copaxone imadutsa mkaka wa m'mawere kapena ngati ingakhudze mwana yemwe akuyamwitsa.

Ngati mukuyamwitsa kapena mukukonzekera kuyamwitsa, lankhulani ndi dokotala wanu ngati Copaxone ili yoyenera kwa inu.

Copaxone ndi mowa

Mowa sudziwika kuti umagwirizana ndi Copaxone. Komabe, ngati muli ndi zovuta zina kuchokera ku Copaxone, monga kuthamanga kapena kusuta, kumwa mowa kumatha kukulitsa mavuto anu.

Copaxone itatulutsidwa pamsika, panali malipoti a anthu omwe amagwiritsa ntchito mankhwalawa osalolera mowa. (Ndikosalolera zakumwa zoledzeretsa, mutha kukhala ndi machitidwe ena mukangomwa mowa. Izi zimatha kuphatikizira kumaso kapena mphuno.)

Komabe, malipoti awa anali osowa. Ndipo kusalolera mowa sikunalumikizidwe mwachindunji ndi kugwiritsa ntchito Copaxone.

Kuopsa kwakumwa mowa mwa anthu omwe ali ndi multiple sclerosis (MS) sikudziwika kwenikweni. Ngati mumamwa mowa, kambiranani ndi dokotala wanu za kuchuluka kwa zomwe muyenera kumwa.

Kuyanjana kwa Copaxone

Palibe kulumikizana kulikonse komwe kumadziwika pakati pa Copaxone ndi mankhwala ena aliwonse, zitsamba, zowonjezera, kapena zakudya.

Komabe, musanatenge Copaxone, lankhulani ndi dokotala komanso wamankhwala. Auzeni zamankhwala onse omwe mumalandira, pa-pakauntala, ndi mankhwala ena omwe mumamwa. Auzeni za mavitamini, zitsamba, ndi zowonjezera zilizonse zomwe mumagwiritsa ntchito. Kugawana izi kungakuthandizeni kupewa kuyanjana komwe kungachitike.

Ngati muli ndi mafunso okhudzana ndi mankhwala omwe angakukhudzeni, funsani dokotala kapena wamankhwala.

Momwe Copaxone imagwirira ntchito

Copaxone imavomerezedwa kuti ithetse mitundu yobwerezabwereza ya multiple sclerosis (MS) ndi matenda omwe amakhala okhaokha (CIS). (CIS ndi vuto lomwe limayambitsa zizindikiro ngati za MS.)

Kodi chimachitika ndi chiyani mu MS?

MS ndimkhalidwe wa nthawi yayitali womwe umakulirakulira pakapita nthawi. Zimakhudza dongosolo lanu lamanjenje (CNS), lomwe limapangidwa ndi ubongo wanu ndi msana. CNS yanu imakhalanso ndi mitsempha yomwe imatumiza mauthenga pakati pa ubongo wanu ndi thupi lanu lonse.

Iliyonse ya minyewa imeneyi imazunguliridwa ndi minofu yotchedwa myelin sheath. Chingwe cha myelin chili ngati zokutira pulasitiki zomwe zimazungulira mawaya mkati mwa chingwe chamagetsi. Ngati m'chimake chawonongeka, mitsempha yanu siyingathenso kutumiza mauthenga.

Ndi MS, chitetezo chanu cha mthupi chimayamba kuwononga molakwika ma sheelin sheath ozungulira misempha yanu. Izi zimayambitsa kutupa komwe kumawononga ma sheelath sheath. Kuwonongeka kumapangitsa kuti zikhale zovuta kuti mitsempha yanu izitumiza ndikulandila mauthenga. Kutengera ndi misempha iti yomwe yawonongeka, zizindikiro zanu za MS zimatha kusiyanasiyana pang'ono.

Chitetezo cha mthupi lanu chikatha kuwononga myelin sheath, zilonda zamiyala zimatha kuzungulira m'malo owonongeka. Minofu yovulalayo imapangitsanso kuti zikhale zovuta kuti mitsempha yanu izitumiza ndi kulandira mauthenga. Madera owonongeka ndi mabala pamitsempha yanu amatchedwa zotupa. Maderawa amatha kuwoneka pazithunzi za MRI, zomwe ndi mayeso oyeserera omwe amagwiritsidwa ntchito kuwunika MS.

Kodi kubwereranso MS ndi chiyani?

Ndi mitundu yobwerezabwereza ya MS, mudzakhala ndi nthawi yomwe matenda anu amayamba kukhala bwino kapena amatha kwathunthu. (Nthawi izi zimatchedwa kukhululukidwa.) Koma mudzakhalanso ndi nthawi yazizindikiro zatsopano za MS, kapena nthawi yomwe matenda anu a MS amabwerera kapena kukulira atatha kusintha. (Nthawi izi zimatchedwa kubwereranso.)

Kukhululukidwa kumachitika maselo amitsempha yanu akamadzikonza okha kuchokera kuwonongeka komwe kumayambitsidwa ndi MS. Kukhululukiranso kumatha kuchitika pamene thupi lanu limapanga njira zatsopano zamitsempha zomwe zimadutsa mitsempha yomwe yawonongeka ndi MS. Nthawi zakhululukidwe zitha kukhala kwa miyezi ingapo mpaka zaka zochepa.

Chigawo chilichonse cha kuwonongeka kwa mitsempha ndi zomwe zimayambitsa zimatha kukhala masiku angapo kapena miyezi ingapo. Izi zimatchedwa kuukira kwa MS kapena MS kubwerera. Popita nthawi, zizindikiro zobwerera m'mbuyo zimatha kukulira kapena kukulirakulira. Kukula kumeneku kumabweretsa zovuta pantchito za tsiku ndi tsiku monga kuyenda kapena kulankhula.

CIS ndi chiyani?

Ndi CIS, muli ndi gawo limodzi lazizindikiro za MS zomwe zimatha pafupifupi maola 24. CIS itha kupita ku MS kapena ayi, koma itha kukhala chizindikiro cha MS. Chifukwa cha izi, nthawi zambiri imagawidwa ndimikhalidwe ina, monga kubwereranso kwa mitundu ya MS.

Kodi Copaxone amachita chiyani?

Copaxone ndi mankhwala osinthira matenda amitundu yobwereranso ya MS, komanso CIS. Imachedwetsa kuwonongeka kwa mitsempha komwe kumayambitsidwa ndi MS komanso kumachepetsa kukula kwa matendawa.

Copaxone imakhala ndi mankhwala osokoneza bongo a glatiramer acetate. Ndi mapuloteni omwe amapangidwa mu labu. Komabe, ndi ofanana kwambiri ndi imodzi mwa mapuloteni omwe mwachilengedwe amapezeka mthupi la myelin.

Copaxone amatchedwa immunomodulator. Zimagwira ntchito posintha zochitika za ma cell ena m'thupi lanu. Ngakhale samamvetsetsa bwino momwe mankhwalawa amagwirira ntchito, amaganiza kuti amayatsa maselo ena oyera am'magazi, otchedwa suppressor T cell. Maselowa amagwira ntchito m'njira zingapo kuyimitsa chitetezo chanu chamthupi kuti chisalimbane ndi minofu yanu ya myelin sheath.

Mukakhala ndi zovuta zochepa pamutu wanu wa myelin, muyenera kukhala ndi MS ochepa kubwerera. Izi zitha kuchepetsa kukulirakulira kwazomwe mukukula komanso kulumala.

Zimatenga nthawi yayitali bwanji kuti zigwire ntchito?

Copaxone iyamba kugwira ntchito posachedwa jekeseni wanu woyamba, koma simungathe kuzindikira kuti ikugwira ntchito. Izi ndichifukwa choti mankhwalawa amathandiza kuti matenda anu asakule kwambiri, m'malo mothana ndi zomwe muli nazo.

Koma mukamalandira chithandizo, dokotala angawone ngati Copaxone ikugwirirani ntchito. Kuti achite izi, atha kuyitanitsa mayeso ena azithunzi, monga MRI scan.

Mtengo wa Copaxone

Monga mankhwala onse, mtengo wa Copaxone umasiyana.

Mtengo weniweni womwe mudzalipira umadalira dongosolo la inshuwaransi yanu, komwe mumakhala, komanso malo ogulitsira mankhwala omwe mumagwiritsa ntchito.

Ndondomeko yanu ya inshuwaransi ingafune kuti mupeze chilolezo musanavomereze Copaxone. Izi zikutanthauza kuti dokotala wanu ndi kampani ya inshuwaransi adzafunika kuti adziwitse za mankhwala anu kampani ya inshuwaransi isanakonze mankhwalawo. Kampani ya inshuwaransi iunikanso pempholi ndikudziwitsani inu ndi dokotala ngati pulani yanu ipanga Copaxone.

Ngati simukudziwa ngati mukufuna kupeza chilolezo cha Copaxone, lemberani kampani yanu ya inshuwaransi.

Thandizo lazachuma komanso inshuwaransi

Ngati mukufuna thandizo lazachuma kuti mulipire Copaxone, kapena ngati mukufuna thandizo kuti mumvetsetse inshuwaransi yanu, thandizo lilipo.

Teva Neuroscience, Inc., wopanga Copaxone, amapereka pulogalamu yotchedwa Shared Solutions. Pulogalamuyi imapereka thandizo lazachuma, kuphatikiza khadi ya copay yomwe ingathandize kutsitsa mtengo wa Copaxone.

Kuti mumve zambiri komanso kuti mudziwe ngati mukuyenera kuthandizidwa, imbani 800-887-8100 kapena pitani patsamba lino.

Mtundu wa generic

Copaxone imapezeka mu mawonekedwe achibadwa otchedwa glatiramer acetate. Mankhwala achibadwa ndi mankhwala enieni a mankhwala omwe ali ndi dzina lodziwika. Mankhwalawa amawoneka kuti ndi otetezeka komanso ogwira ntchito ngati mankhwala oyamba. Ndipo ma generic amawononga mtengo wotsika poyerekeza ndi mankhwala omwe amadziwika ndi dzina.

Kuti mudziwe momwe mtengo wa genatiramer acetate ukuyerekeza ndi mtengo wa Copaxone, pitani ku GoodRx.com. Apanso, mtengo womwe mumapeza pa GoodRx.com ndiomwe mungalipire popanda inshuwaransi. Mtengo weniweni womwe mudzalipira umadalira dongosolo la inshuwaransi yanu, komwe mumakhala, komanso malo ogulitsira mankhwala omwe mumagwiritsa ntchito.

Ngati dokotala wanu wakupatsani Copaxone ndipo mukufuna kugwiritsa ntchito generic glatiramer acetate m'malo mwake, lankhulani ndi dokotala wanu. Amatha kukhala ndi zokonda zamtundu wina kapena zinazo. Muyeneranso kuwunika inshuwaransi yanu, chifukwa imangokhudza chimodzi kapena chimzake.

Njira zopewera Copaxone

Musanatenge Copaxone, kambiranani ndi dokotala za mbiri yanu. Copaxone mwina siyabwino kwa inu ngati muli ndi zovuta zina zamankhwala kapena zina zomwe zimakhudza thanzi lanu. Izi zikuphatikiza:

• Zovuta za Copaxone. Musatenge Copaxone ngati munayamba mwakumana ndi Copaxone, glatiramer acetate (mankhwala omwe amagwiritsidwa ntchito ku Copaxone), kapena mannitol (chinthu chosagwira ntchito ku Copaxone). Ngati simukudziwa za matenda anu a mankhwala, kambiranani ndi dokotala wanu.
• Mimba. Sidziwika ngati Copaxone ndi yotetezeka kugwiritsa ntchito nthawi yapakati. Kuti mumve zambiri, onani gawo la "Copaxone and pregnancy" pamwambapa.
• Kuyamwitsa. Sidziwika ngati Copaxone imadutsa mkaka wa m'mawere. Kuti mumve zambiri, onani gawo la "Copaxone ndi yoyamwitsa" pamwambapa.

Zindikirani: Kuti mumve zambiri za zotsatira zoyipa za Copaxone, onani gawo la "Zotsatira za Copaxone" pamwambapa.

Kuledzera kwa Copaxone

Musagwiritse ntchito Copaxone yochulukirapo kuposa momwe dokotala akuwalimbikitsira. Kwa mankhwala ena, kutero kumatha kubweretsa mavuto osafunikira kapena bongo.

Zoyenera kuchita ngati mwatenga Copaxone wambiri

Ngati mukuganiza kuti mwamwa kwambiri mankhwalawa, itanani dokotala wanu. Muthanso kuyitanitsa American Association of Poison Control Center ku 800-222-1222 kapena kugwiritsa ntchito chida chawo pa intaneti. Koma ngati matenda anu akukulira, itanani 911 kapena pitani kuchipatala chapafupi pomwepo.

Zambiri zamaluso za Copaxone

Zotsatirazi zimaperekedwa kwa azachipatala ndi ena othandizira azaumoyo.

Zisonyezero

Copaxone imavomerezedwa kuti ikwaniritse izi:

• matenda opatsirana (CIS)
• Kubwezeretsanso MS (RRMS)
• MS yachiwiri yogwira ntchito (SPMS)

Njira yogwirira ntchito

Copaxone ndi mankhwala osintha matenda omwe ali ndi mankhwala osokoneza bongo a glatiramer acetate. Ndi mankhwala osokoneza bongo, ngakhale sizimveka bwino momwe amagwirira ntchito.

Glatiramer acetate ndi yopanga mapuloteni molekyulu omwe amafanana ndi amodzi mwa mapuloteni achilengedwe omwe amapezeka mu myelin. Zikuwoneka kuti zimayambitsa ma cell a T opondereza omwe amalepheretsa chitetezo cha mthupi ku myelin.

Glatiramer potero amachepetsa chitetezo cha mthupi pa myelin, zomwe zimapangitsa kuti MS ichepetse kubwerera ndikuchepetsa kukula kwa matendawa.

Pharmacokinetics ndi metabolism

Copaxone yochulukirapo imasungunuka ndi tinthu tating'onoting'ono tomwe timayendetsedwa. Copaxone yonse yosasunthika komanso yama hydrolyzed imalowa m'magazi amitsempha komanso amachitidwe. Hafu ya moyo wa Copaxone sadziwika.

Zotsutsana

Copaxone sayenera kugwiritsidwa ntchito mwa anthu omwe ali ndi vuto lodana ndi glatiramer acetate kapena mannitol.

Yosungirako

Sungani Copaxone mufiriji pazotentha za 36 ° F mpaka 46 ° F (2 ° C mpaka 8 ° C). Sungani mankhwalawo phukusi loyambirira. Osazizira. Ngati jakisoni wa Copaxone wasungunuka, musagwiritse ntchito.

Ngati zingafunike, Copaxone imatha kusungidwa kutentha (59 ° F mpaka 86 ° F / 15 ° C mpaka 30 ° C) mpaka mwezi umodzi.

Chodzikanira: Medical News Today yachita zonse zotheka kuti zitsimikizire kuti chidziwitso chonse ndicholondola, chokwanira, komanso chaposachedwa. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi ukadaulo wa akatswiri pazachipatala. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse. Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizingapangidwe kuti zigwiritse ntchito, mayendedwe, zodzitetezera, machenjezo, kulumikizana ndi mankhwala, kusokonezeka, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso za mankhwala omwe apatsidwa sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera kwa odwala onse kapena ntchito zina zilizonse.