Kodi Glucosamine Imagwira? Ubwino, Mlingo ndi Zotsatira zoyipa

Zamkati

• Kodi Glucosamine ndi chiyani?
• Angachepetse Kutupa
• Imathandiza olowa Healthy
• Nthawi zambiri amagwiritsidwa ntchito pochiza mafupa ndi ziwalo
• Ntchito Zina za Glucosamine
• Kuphatikizana kwa Cystitis
• Matenda Opopa Matenda (IBD)
• Multiple Sclerosis (MS)
• Glaucoma
• Olowa Temporomandibular (TMJ)
• Kodi Zimathandizadi?
• Mlingo ndi Mafomu Owonjezera
• Zowopsa zomwe zingachitike ndi zoyipa zake
• Mfundo Yofunika Kwambiri

Glucosamine ndi molekyu yomwe imachitika mwachilengedwe m'thupi lanu, komanso ndiwowonjezera wodziwika bwino wazakudya.

Nthawi zambiri amagwiritsidwa ntchito pochiza matenda am'mafupa komanso molumikizana mafupa, amagwiritsidwanso ntchito kuthana ndi matenda ena angapo otupa.

Nkhaniyi ikufufuza zaubwino wa glucosamine, kuchuluka kwake ndi zoyipa zake.

Kodi Glucosamine ndi chiyani?

Glucosamine ndimapangidwe achilengedwe omwe amadziwika kuti ndi amino shuga (1).

Imakhala ngati gawo lomanga mamolekyulu osiyanasiyana ogwirira ntchito m'thupi lanu koma amadziwika makamaka pakukula ndi kusungunuka kwamafupa m'magulu anu (1).

Glucosamine imapezekanso munyama zina ndi ziwalo zina zomwe sianthu, kuphatikiza zipolopolo za nkhono zam'madzi, mafupa a nyama ndi bowa. Mitundu yowonjezera ya glucosamine nthawi zambiri imapangidwa kuchokera kuzinthu zachilengedwezi (2).

Glucosamine imagwiritsidwa ntchito pafupipafupi pochiza komanso kupewa zovuta zamagulu, monga osteoarthritis. Amatha kumwedwa pakamwa kapena kupaka pamutu mu kirimu kapena salve (2).

Glucosamine ndi mankhwala omwe amapezeka mwachilengedwe mwa anthu komanso nyama. Mwa anthu, zimathandizira kupanga karotila ndipo amagwiritsidwa ntchito ngati chakudya chowonjezera kuti athetse zovuta zamagulu monga osteoarthritis.

Angachepetse Kutupa

Glucosamine imagwiritsidwa ntchito mophatikizira pochiza zizindikiritso zosiyanasiyana.

Ngakhale njira za glucosamine sizimamvetsetseka bwino, zikuwoneka kuti zimachepetsa kutupa.

Kafukufuku wina wazoyeserera adawonetsa chidwi chotsutsana ndi zotupa pomwe glucosamine imagwiritsidwa ntchito m'maselo omwe amakhudzidwa ndimafupa ().

Kafukufuku wambiri wokhudza glucosamine amaphatikizira nthawi imodzi ndi chondroitin - chida chofanana ndi glucosamine, chomwe chimakhudzanso thupi lanu ndikupanga khungu labwino (4).

Kafukufuku mwa anthu opitilira 200 omwe adalumikizana ndi glucosamine othandizira kuti 28% ndi 24% ichepetse magawo awiri am'magazi am'mimba: CRP ndi PGE. Komabe, zotsatirazi sizinali zofunikira kwenikweni ().

Tiyenera kudziwa kuti kafukufuku yemweyo adapeza kutsika kwa 36% kwa zotupa zoterezi kwa anthu omwe amatenga chondroitin. Chotsatira ichi chinali chofunika ().

Kafukufuku wina adalimbikitsa izi. Kumbukirani kuti ambiri omwe amatenga chondroitin amafotokozanso nthawi imodzi ndi glucosamine.

Chifukwa chake, sizikudziwika ngati zotsatira zake zimayendetsedwa ndi chondroitin yokha kapena kuphatikiza zonse ziwiri zomwe zimapangidwa pamodzi ().

Pomaliza, pakufunika kafukufuku wambiri pa gawo la glucosamine pochepetsa zipsera zotupa mthupi lanu.

Momwe glucosamine imagwirira ntchito pochiza matenda samamveka bwino, koma kafukufuku wina akuwonetsa kuti imatha kuchepetsa kutupa - makamaka ikagwiritsidwa ntchito limodzi ndi ma chondroitin othandizira.

Imathandiza olowa Healthy

Glucosamine amapezeka mwachilengedwe mthupi lanu. Imodzi mwamaudindo ake akulu ndikuthandizira kukulira kwaminyewa pakati pamagulu anu (1).

Cartilage yapadera ndi mtundu wa minofu yoyera yoyera yomwe imakuta malekezero a mafupa anu komwe amakumana kuti apange ziwalo.

Minofu yamtunduwu - kuphatikizira ndi madzi othira mafuta otchedwa synovial fluid - amalola mafupa kuti aziyenda momasuka, ndikuchepetsa mikangano ndikulola kusuntha kopweteka pamafundo anu.

Glucosamine imathandizira kupanga mitundu ingapo yamankhwala omwe amaphatikizidwa pakupanga kachulukidwe ka articular ndi synovial fluid.

Kafukufuku wina akuwonetsa kuti supplemental glucosamine itha kuteteza minofu yolumikizana poletsa kuwonongeka kwa karoti.

Kafukufuku wocheperako mwa okwera njinga za 41 adapeza kuti kuwonjezera mpaka magalamu atatu a glucosamine tsiku lililonse kumachepetsa kuwonongeka kwa collagen m'mabondo ndi 27% poyerekeza ndi 8% pagulu la placebo ().

Kafukufuku wina wocheperako adapeza kuchepa kwambiri kwa collagen-breakers to collagen-synthesis marker in articular joints of players players treated with 3 gramu of glucosamine tsiku lililonse kwa miyezi itatu ().

Zotsatira izi zikuwonetsa kutetezedwa kophatikizana kwa glucosamine. Komabe, kafukufuku wina amafunika.

Glucosamine imathandizira kupanga ziwalo zofunikira kuti mugwirizane bwino. Ngakhale maphunziro ena ndi ofunikira, kafukufuku wina akuwonetsa kuti supplemental glucosamine itha kuteteza malumikizidwe anu kuti asawonongeke.

Nthawi zambiri amagwiritsidwa ntchito pochiza mafupa ndi ziwalo

Mavitamini a Glucosamine amatengedwa nthawi zambiri kuti athetse vuto la mafupa ndi olowa.

Molekyuluyi yawerengedwa makamaka kuti imatha kuchiza matenda komanso kukula kwa matenda okhudzana ndi nyamakazi, nyamakazi ya nyamakazi ndi kufooka kwa mafupa.

Kafukufuku wambiri akuwonetsa kuti kuwonjezera tsiku lililonse ndi glucosamine sulphate kumatha kupereka chithandizo chothandiza kwa nthawi yayitali cha osteoarthritis powapatsa kuchepa kwakukulu kwa zowawa, kukonza malo olowa komanso kuchepa kwa matenda (,, 10, 11).

Kafukufuku wina adavumbulutsa kuchepa kwamatenda a nyamakazi (RA) mu mbewa zomwe zimathandizidwa ndi mitundu yosiyanasiyana ya glucosamine (,).

Mosiyana ndi izi, kafukufuku wamunthu sanawonetse kusintha kulikonse pakukula kwa RA pogwiritsa ntchito glucosamine. Komabe, omwe adachita nawo kafukufukuyu adanenanso zakusintha kwa chizindikiritso ().

Kafukufuku wina woyambirira wama mbewa omwe ali ndi kufooka kwa mafupa amawonetsanso kuthekera kokugwiritsa ntchito glucosamine kukonza mphamvu ya mafupa ().

Ngakhale zotsatirazi ndizolimbikitsa, kafukufuku wambiri waumunthu amafunikira kuti amvetsetse momwe angagwiritsire ntchito glucosamine m'matenda olumikizana ndi mafupa.

Ngakhale glucosamine imagwiritsidwa ntchito pafupipafupi pochiza mafupa osiyanasiyana ndi mafupa olumikizana, kufufuza kwina pazotsatira zake kumafunikira.

Ntchito Zina za Glucosamine

Ngakhale anthu amagwiritsa ntchito glucosamine pochiza matenda osiyanasiyana otupa, zambiri za sayansi zothandizirako ndizochepa.

Kuphatikizana kwa Cystitis

Glucosamine imalimbikitsidwa kwambiri ngati chithandizo cha interstitial cystitis (IC), vuto lomwe limakhudzana ndi kusowa kwa mankhwalawa glycosaminoglycan.

Chifukwa glucosamine ndiyotsogola pachipindachi, akuti amathandizira ma glucosamine othandizira kuthandizira IC ().

Tsoka ilo, deta yodalirika yasayansi yothandizira mfundoyi ikusowa.

Matenda Opopa Matenda (IBD)

Monga interstitial cystitis, matenda opweteka am'mimba (IBD) amathandizidwa ndi kuchepa kwa glycosaminoglycan ().

Kafukufuku wocheperako amathandizira lingaliro loti glucosamine imatha kuchiza IBD. Komabe, kafukufuku wama mbewa omwe ali ndi IBD adawonetsa kuti kuwonjezera ndi glucosamine kumatha kuchepetsa kutupa ().

Pomaliza, kafukufuku wina amafunika kuti apeze mayankho otsimikizika.

Multiple Sclerosis (MS)

Olemba ena amati glucosamine atha kukhala mankhwala othandiza a multiple sclerosis (MS). Komabe, kuthandizira kafukufuku sikusowa.

Kafukufuku wina adawonetsa momwe kugwiritsa ntchito glucosamine sulphate limodzi ndi mankhwala achikhalidwe pakubwezeretsanso kwa MS. Zotsatira sizinawonongeke pakubwezeretsanso kapena kupitilira kwa matenda chifukwa cha glucosamine ().

Glaucoma

Glaucoma imakhulupirira kuti imachiritsidwa ndi glucosamine.

Kafukufuku woyambirira akuwonetsa kuti glucosamine sulphate ingalimbikitse thanzi la diso kudzera pakuchepetsa kutupa komanso zotsatira za antioxidant mu retina yanu).

Mosiyana ndi izi, kafukufuku wina wocheperako adawonetsa kuti kudya kwambiri glucosamine kumatha kuvulaza anthu omwe ali ndi glaucoma ().

Zonsezi, zomwe zilipo pakadali pano ndizosadziwika.

Olowa Temporomandibular (TMJ)

Ena amati glucosamine ndi mankhwala othandiza a TMJ, kapena olowa mu temporomandibular. Komabe, kafukufuku wotsimikizira izi sikokwanira.

Kafukufuku wina wocheperako adawonetsa kuchepa kwakukulu kwa zopweteka ndi zotupa, komanso kuchuluka kwa nsagwada mwa omwe atenga nawo gawo omwe adalandira kuphatikiza kwa glucosamine sulphate ndi chondroitin ().

Kafukufuku wina wocheperako sanawone zotsatira zakanthawi kochepa za glucosamine hydrochloride zowonjezera kwa anthu omwe ali ndi TMJ. Komabe, kusintha kwakukulu pakusamalira kwakanthawi kwakanthawi kunanenedwa ().

Zotsatira za kafukufukuzi zikulonjeza koma sizipereka deta yokwanira kuti zithandizire zomaliza zilizonse. Kafufuzidwe kena kofunikira.

Ngakhale glucosamine nthawi zambiri imawerengedwa ngati mankhwala othandiza pazinthu zosiyanasiyana, palibe chidziwitso chotsimikizika pazokhudza zake.

Kodi Zimathandizadi?

Ngakhale zonena zazikuluzikulu zimanenedwa pazokhudza zabwino za glucosamine pamatenda ambiri, kafukufuku wopezeka amangogwiritsira ntchito magwiritsidwe ake ochepa.

Pakadali pano, umboni wamphamvu kwambiri umathandizira kugwiritsa ntchito glucosamine sulphate pochiza matenda a osteoarthritis kwakanthawi. Izi zati, sizingagwire ntchito kwa aliyense ().

Malinga ndi zomwe zilipo, ndizochepa kukhala njira yabwino yothandizira matenda ena kapena zotupa.

Ngati mukuganiza zogwiritsa ntchito glucosamine, kumbukirani mtundu wa chowonjezera chomwe mungasankhe - chifukwa izi zitha kupanga kusiyana kwamomwe zimakukhudzirani.

M'mayiko ena - kuphatikiza US - pamakhala malamulo ochepa kwambiri pazowonjezera zakudya. Chifukwa chake, zolemba zitha kukhala zachinyengo (2).

Nthawi zonse ndibwino kuti mufufuze chiphaso chachitatu kuti muwonetsetse kuti mukulandiradi zomwe mumalipira. Opanga omwe amafuna kuti zinthu zawo ziyesedwe kuti ndi zoyera ndi munthu wina amakhala ndi miyezo yapamwamba.

ConsumerLab, NSF International ndi US Pharmacopeia (USP) ndi makampani ochepa odziyimira pawokha omwe amapereka ziphaso. Ngati muwona chimodzi mwazizindikiro zawo pazowonjezera zanu, mwina ndizabwino.

Kafukufuku wambiri amathandizira kugwiritsa ntchito glucosamine-sulphate yongothana ndi matenda a osteoarthritis. Ndizochepa kuti zitheke pantchito zina.

Mlingo ndi Mafomu Owonjezera

Mlingo wa glucosamine ndi 1,500 mg patsiku, womwe mutha kumwa kamodzi kapena pang'ono pang'ono tsiku lonse (2).

Mavitamini a Glucosamine amapangidwa kuchokera kuzinthu zachilengedwe - monga nkhono za nkhono kapena bowa - kapena zopangidwa mwaluso labu.

Zowonjezera za Glucosamine zimapezeka m'njira ziwiri (1):

• Glucosamine sulphate
• Glucosamine hydrochloride

Nthawi zina, glucosamine sulphate imagulitsidwanso kuphatikiza ndi chondroitin sulphate.

Zambiri zamasayansi zimawonetsa kufunikira kwakukulu kwa glucosamine sulphate kapena glucosamine sulphate yophatikizidwa ndi chondroitin.

Glucosamine nthawi zambiri amathiridwa 1,500 mg patsiku. Mwa mitundu yomwe ilipo, glucosamine sulphate - kapena yopanda chondroitin - ndiyomwe ndiyothandiza kwambiri.

Zowopsa zomwe zingachitike ndi zoyipa zake

Zowonjezera za glucosamine mwina ndizotetezeka kwa anthu ambiri. Komabe, pali zoopsa zina.

Zovuta zomwe zingachitike ndi monga (1):

• Nseru ndi kusanza
• Kutsekula m'mimba
• Kutentha pa chifuwa
• Kupweteka m'mimba

Simuyenera kumwa glucosamine ngati muli ndi pakati kapena mukuyamwitsa chifukwa chosowa umboni wotsimikizira chitetezo chake.

Glucosamine itha kukulitsa kuwongolera shuga wamagazi kwa anthu omwe ali ndi matenda ashuga, ngakhale izi zili zochepa. Ngati muli ndi matenda ashuga kapena mukumwa mankhwala a shuga, kambiranani ndi dokotala musanatenge glucosamine (2).

Glucosamine ndiyotetezeka kwa anthu ambiri. Amamva kukwiya pang'ono m'mimba. Ngati muli ndi matenda ashuga, glucosamine imatha kukulitsa mphamvu yolamulira shuga.

Mfundo Yofunika Kwambiri

Glucosamine imakhalapo mwachilengedwe mthupi lanu ndipo imagwira ntchito yofunikira pakukula ndi kusamalira malo olimba.

Ngakhale glucosamine imagwiritsidwa ntchito pochiza matenda osiyanasiyana ophatikizana, mafupa ndi yotupa, monga IBD, interstitial cystitis ndi TMJ, kafukufuku ambiri amangothandiza pakuthandizira kuwongolera zizindikiritso za osteoarthritis.

Zikuwoneka ngati zotetezeka kwa anthu ambiri pamlingo wa 1,500 mg patsiku koma zimatha kuyambitsa zovuta zina.

Ngati mukufuna chithandizo cha nyamakazi, kumwa mankhwala a glucosamine kungakhale koyenera kulingalira, koma onetsetsani kuti mwalankhula ndi dokotala poyamba.