Kadcyla

Zamkati

• Zisonyezero za Kadcyla
• Mtengo wa Kadcyla
• Momwe mungagwiritsire ntchito Kadcyla
• Zotsatira zoyipa za Kadcyla
• Zotsutsana za Kadcyla

Kadcyla ndi mankhwala omwe amawonetsedwa ngati chithandizo cha khansa ya m'mawere yokhala ndi metatheses zingapo mthupi. Mankhwalawa amagwira ntchito poletsa kukula ndi mapangidwe a metastases yatsopano ya khansa.

Kadcyla ndi mankhwala opangidwa ndi kampani yopanga mankhwala a Roche.

Zisonyezero za Kadcyla

Kadcyla amawonetsedwa ngati chithandizo cha khansa ya m'mawere yomwe ili kale msinkhu ndipo yafalikira kale mbali zina za thupi. Nthawi zambiri amapatsidwa kwa wodwalayo mankhwala ena a khansa atapatsidwa ndipo sanachite bwino.

Mankhwala a Kadcyla amapangidwa ndi mankhwala awiri, trastuzumab yomwe imalepheretsa kukula kwa maselo a khansa komanso mertansine yomwe imalowa m'maselo ndi kuwawononga, kuchepetsa chotupacho komanso kupita patsogolo kwa matendawa, komanso kutalikitsa moyo wa wodwalayo.

Mtengo wa Kadcyla

Mtengo wa Kadcyla pamwezi ndi $ 9800, pomwe chithandizo cha miyezi 9.6 chimawononga $ 94,000.

Momwe mungagwiritsire ntchito Kadcyla

Mlingo woyenera wa Kadcyla ndi 3.6 mg / kg ndipo umaperekedwa ndi jakisoni wobaya m'masabata atatu aliwonse.

Pachithandizo choyamba, mankhwalawa amayenera kuperekedwa kwa mphindi 90, odwala akuwonedwa kuti awone ngati ali ndi zotsatirapo zake. Ngati bwino analekerera, mankhwala ayenera kuperekedwa kwa mphindi 30.

Mlingo wopitilira 3.6 mg / kg sayenera kuperekedwa.

Zotsatira zoyipa za Kadcyla

Zotsatira zoyipa za Kadcyla ndi izi:

• Kutopa;
• Nseru ndi kusanza:
• Kupweteka kwa minofu;
• Kuchepetsa kuchuluka kwa ma platelet m'magazi;
• Mutu;
• Kuchuluka transaminases chiwindi;
• Kuzizira.

Zotsutsana za Kadcyla

Kadcyla imatsutsana panthawi yapakati chifukwa imayambitsa mavuto akulu am'mimba mwa mwana.

Mankhwala ena amatha kulumikizana ndi Kadcyla monga

• Imatinib;
• Isoniazid;
• Clarithromycin ndi telithromycin;
• Mankhwala antifungal;
• Mankhwala amtima: nicardipine, quinidine;
• Mankhwala a hepatitis C: boceprevir, telaprevir;
• Mankhwala a Edzi;
• Mavitamini ndi zinthu zachilengedwe.

Dokotala amayenera kudziwitsidwa nthawi zonse za mankhwala omwe wodwalayo amagwiritsa ntchito pafupipafupi kapena omwe akumwa panthawi yomwe ayamba kulandira chithandizo.