Matenda a Waldenstrom

Zamkati

• Kodi Zizindikiro Za Matenda a Waldenstrom Ndi Ziti?
• Kodi Zimayambitsa Matenda a Waldenstrom Ndi Chiyani?
• Kodi Matenda a Waldenstrom Amapezeka Bwanji?
• Kodi Matenda a Waldenstrom Amachiritsidwa Motani?
• Chemotherapy
• Plasmapheresis
• Biotherapy
• Opaleshoni
• Mayeso Amatenda
• Kodi Chiyembekezo Chosakhalitsa Ndi Chiyani?

Kodi Matenda a Waldenstrom Ndi Chiyani?

Chitetezo chanu cha mthupi chimapanga maselo omwe amateteza thupi lanu ku matenda. Selo limodzi lotere ndi B lymphocyte, yomwe imadziwikanso kuti B cell. Maselo a B amapangidwa m'mafupa. Amasunthira ndikukula m'matenda anu am'mimba ndi ndulu. Amatha kukhala maselo am'magazi, omwe ali ndi udindo wotulutsa antibody wotchedwa immunoglobulin M, kapena IgM. Ma antibodies amagwiritsidwa ntchito ndi thupi lanu kuthana ndi matenda obwera.

Nthawi zambiri, thupi lanu limatha kuyamba kupanga IgM yambiri. Izi zikachitika, magazi anu amakula. Izi zimadziwika kuti hyperviscosity, ndipo zimapangitsa kuti ziwalo zanu zonse ndi ziwalo zanu zizigwira bwino ntchito. Matendawa omwe thupi lanu limapanga IgM yochulukirapo amadziwika kuti matenda a Waldenstrom. Ndi mwaukadaulo mtundu wa khansa.

Matenda a Waldenstrom ndi khansa yosowa. American Cancer Society (ACS) akuti pali pafupifupi 1,100 mpaka 1,500 odwala matenda a Waldenstrom omwe amapezeka chaka chilichonse ku United States. Matendawa ndi a non-Hodgkin lymphoma omwe amakula pang'onopang'ono. Matenda a Waldenstrom amadziwikanso kuti:

• Macroglobulinemia ya Waldenstrom
• lymphoplasmacytic lymphoma
• chachikulu macroglobulinemia

Kodi Zizindikiro Za Matenda a Waldenstrom Ndi Ziti?

Zizindikiro za matenda a Waldenstrom zimasiyanasiyana kutengera kukula kwa matenda anu. Nthawi zina, anthu omwe ali ndi vutoli alibe zisonyezo. Zizindikiro zofala kwambiri za matendawa ndi izi:

• kufooka
• kutopa
• Kutuluka magazi m'kamwa kapena mphuno
• kuonda
• mikwingwirima
• zotupa pakhungu
• khungu
• zotupa zotupa

Ngati kuchuluka kwa IgM mthupi lanu kumakula kwambiri, mutha kukhala ndi zizindikilo zina. Zizindikirozi zimachitika kawirikawiri chifukwa cha kukhudzika mtima ndipo zimaphatikizapo:

• masomphenya amasintha, kuphatikiza kuwona bwino komanso kutaya masomphenya
• kupweteka mutu
• chizungulire kapena chizungulire
• kusintha kwa malingaliro

Kodi Zimayambitsa Matenda a Waldenstrom Ndi Chiyani?

Matenda a Waldenstrom amayamba thupi lanu likawonjezera ma antibodies a IgM. Zomwe zimayambitsa matendawa sizikudziwika.

Matendawa ndiofala kwambiri pakati pa anthu omwe ali ndi mabanja omwe ali ndi matendawa. Izi zikusonyeza kuti mwina ndi cholowa.

Kodi Matenda a Waldenstrom Amapezeka Bwanji?

Kuti mupeze matendawa, adokotala ayamba ndikuwunika ndikukufunsani zaumoyo wanu. Dokotala wanu amatha kuwona kutupa m'matenda anu, chiwindi, kapena ma lymph node mukamayesa.

Ngati muli ndi zizindikiro za matenda a Waldenstrom, dokotala wanu atha kuyitanitsa mayeso ena kuti mutsimikizire kuti mwapezeka. Mayesowa atha kuphatikiza:

• kuyesa magazi kuti adziwe kuchuluka kwa IgM ndikuwunika kuchuluka kwa magazi anu
• chifuwa chachikulu cha mafupa
• Kujambula kwa CT kwamafupa kapena minofu yofewa
• X-ray ya mafupa kapena minofu yofewa

CT scan ndi X-ray ya mafupa ndi minofu yofewa imagwiritsidwa ntchito kusiyanitsa matenda a Waldenstrom ndi mtundu wina wa khansa yotchedwa multiple myeloma.

Kodi Matenda a Waldenstrom Amachiritsidwa Motani?

Palibe mankhwala a matenda a Waldenstrom. Komabe, chithandizo chitha kukhala chothandiza kuwongolera zizindikiritso zanu. Chithandizo cha matenda a Waldenstrom chidzadalira kuopsa kwa zizindikiro zanu. Ngati muli ndi matenda a Waldenstrom popanda zizindikiro zilizonse zosokoneza, dokotala wanu sangakulimbikitseni chithandizo chilichonse. Simungafunike chithandizo mpaka mutakhala ndi zizindikilo. Izi zitha kutenga zaka zingapo.

Ngati muli ndi zizindikiro za matendawa, pali mankhwala osiyanasiyana omwe dokotala angakulimbikitseni. Izi zikuphatikiza:

Chemotherapy

Chemotherapy ndi mankhwala omwe amawononga maselo mthupi omwe amakula mwachangu. Mutha kulandira mankhwalawa ngati piritsi kapena kudzera m'mitsempha, zomwe zikutanthauza kudzera mumitsempha yanu. Chemotherapy ya matenda a Waldenstrom yapangidwa kuti iwononge maselo osadziwika omwe amapanga IgM yochulukirapo.

Plasmapheresis

Plasmapheresis, kapena kusinthana kwa plasma, ndi njira yomwe mapuloteni owonjezera otchedwa IgM immunoglobulins mu plasma amachotsedwa m'magazi ndi makina, ndipo plasma yotsalayo imaphatikizidwa ndi plasma yopereka ndikubwezeretsanso thupi.

Biotherapy

Biotherapy, kapena mankhwala othandizira, amagwiritsidwa ntchito kupititsa patsogolo chitetezo cha mthupi kuthana ndi khansa. Itha kugwiritsidwa ntchito ndi chemotherapy.

Opaleshoni

Ndizotheka kuti dokotala wanu angakulimbikitseni kuchitidwa opaleshoni kuti muchotse ndulu. Izi zimatchedwa splenectomy. Anthu omwe ali ndi njirayi amatha kuchepetsa kapena kuthetsa zizindikilo zawo kwazaka zambiri. Komabe, zizindikiro za matendawa nthawi zambiri zimabwerera mwa anthu omwe akhala ndi splenectomy.

Mayeso Amatenda

Mukazindikira, muyenera kufunsa dokotala wanu zamayesero azachipatala za mankhwala atsopano ndi njira zochizira matenda a Waldenstrom. Mayesero azachipatala nthawi zambiri amagwiritsidwa ntchito kuyesa mankhwala atsopano kapena kufufuza njira zatsopano zogwiritsira ntchito mankhwala omwe alipo kale. National Cancer Institute itha kukhala ikuthandizira zoyeserera zamankhwala zomwe zingakupatseni zochiritsira zowonjezera kuti muthane ndi matendawa.

Kodi Chiyembekezo Chosakhalitsa Ndi Chiyani?

Ngati mwapezeka kuti muli ndi matenda a Waldenstrom, malingaliro adzadalira kukula kwa matenda anu. Matendawa amakula mosiyanasiyana malinga ndi munthuyo. Anthu omwe amadwala pang'onopang'ono amakhala ndi nthawi yayitali poyerekeza ndi omwe matenda awo amakula msanga. Malinga ndi nkhani yomwe ili, malingaliro a matenda a Waldenstrom amatha kusiyanasiyana. Avereji ya kupulumuka kumakhala zaka zisanu mpaka pafupifupi 11 atapezeka ndi matenda.