Mlembi: Gregory Harris
Tsiku La Chilengedwe: 10 Epulo 2021
Sinthani Tsiku: 22 Novembala 2024
Anonim
L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?
Kanema: L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?

Zamkati

5-HTP (5-hydroxytryptophan) ndi mankhwala ochokera ku puloteni L-tryptophan. Amapangidwa kuchokera ku malonda kuchokera ku mbewu za chomera cha ku Africa chotchedwa Griffonia simplicifolia.

5-HTP imagwiritsidwa ntchito pamavuto akugona monga kusowa tulo, kukhumudwa, nkhawa, ndi zina zambiri, koma palibe umboni wabwino wasayansi wotsimikizira izi.

Mankhwala Achilengedwe Pazonse mitengo yogwira ntchito potengera umboni wasayansi molingana ndi muyeso wotsatirawu: Wogwira Mtima, Wogwira Mtima, Mwinanso Wogwira Ntchito, Mwinanso Wosagwira Ntchito, Mwinanso Wosagwira Ntchito, Wosagwira Ntchito, Ndi Umboni Wosakwanira Wowerengera.

Kuchita bwino kwa 5-HTP ndi awa:

Mwina zothandiza ...

  • Matenda okhumudwa. Kutenga 5-HTP pakamwa kumawoneka ngati kukuwongolera zizindikilo za kukhumudwa kwa anthu ena. Kafukufuku wina wamankhwala akuwonetsa kuti kumwa 5-HTP pakamwa kumatha kukhala kothandiza monga mankhwala ena opatsirana kupsinjika maganizo kuti athetse vuto lakukhumudwa. M'maphunziro ambiri, 150-800 mg tsiku lililonse la 5-HTP idatengedwa. Nthawi zina, mankhwala apamwamba akhala akugwiritsidwa ntchito.

Mwina sizothandiza kwa ...

  • Matenda a Down. Kafukufuku wina akuwonetsa kuti kupereka 5-HTP kwa makanda omwe ali ndi Down syndrome kumatha kusintha minofu ndi zochitika. Kafukufuku wina akuwonetsa kuti sizimapangitsa kusintha kwa minofu kapena kukula ikatengedwa kuyambira ukhanda mpaka zaka 3-4. Kafukufuku akuwonetsanso kuti kumwa 5-HTP limodzi ndi mankhwala ochiritsira amakulitsa chitukuko, maluso ochezera, kapena luso la chilankhulo.

Umboni wosakwanira woti ungagwire bwino ntchito ...

  • Mtundu wa nkhawa yomwe imadziwika ndimaganizo obwerezabwereza ndi machitidwe obwerezabwereza (kukakamira-kukakamiza kapena OCD). Kafukufuku woyambirira akuwonetsa kuti kutenga 5-HTP ndi antidepressant drug fluoxetine (Prozac) milungu 12 kumatha kusintha zizindikilo zina za OCD.
  • Kusokonezeka kwa mowa. Kafukufuku woyambirira akuwonetsa kuti kutenga 5-HTP ndi D-phenylalanine ndi L-glutamine masiku 40 kumatha kuchepetsa zizindikiritso zakumwa mowa. Komabe, kutenga 5-HTP ndi carbidopa tsiku lililonse kwa chaka chimodzi sikuwoneka kuti kumathandiza anthu kusiya kumwa. Zotsatira za 5-HTP yokha yauchidakwa sizidziwika.
  • Matenda a Alzheimer. Kafukufuku woyambirira akuwonetsa kuti kutenga 5-HTP pakamwa sikuthandiza zizindikiro za matenda a Alzheimer's.
  • Nkhawa. Umboni pazotsatira za 5-HTP pazovuta sizikudziwika. Kafukufuku woyambirira akuwonetsa kuti kutenga 25-150 mg ya 5-HTP pakamwa tsiku lililonse komanso carbidopa zikuwoneka kuti kumachepetsa zizindikiritso za anthu omwe ali ndi vuto la nkhawa. Komabe, kafukufuku wina woyambirira akuwonetsa kuti kumwa kwambiri 5-HTP, 225 mg tsiku lililonse kapena kupitilira apo, kumawoneka kuti kumawonjezera nkhawa. Komanso, kutenga 60 mg ya 5-HTP tsiku ndi tsiku kudzera mumitsempha sikuchepetsa nkhawa kwa anthu omwe ali ndi nkhawa.
  • Kuwonongeka kwaubongo komwe kumakhudza kuyenda kwa minofu (cerebellar ataxia). Umboni wogwiritsa ntchito 5-HTP ya cerebellar ataxia sichikudziwika bwinobwino. Umboni woyambirira ukuwonetsa kuti kutenga 5 mg / kg ya 5-HTP tsiku lililonse kwa miyezi 4 kumatha kuchepa kwamitsempha yamagetsi. Komabe, kafukufuku wina akuwonetsa kuti kutenga 5-HTP tsiku lililonse mpaka chaka chimodzi sikuthandizira kusintha kwa cerebellar ataxia.
  • Fibromyalgia. Kafukufuku woyambirira akuwonetsa kuti kutenga 100 mg ya 5-HTP pakamwa katatu tsiku lililonse kwa masiku 30-90 kumatha kupititsa patsogolo ululu, kukoma mtima, kugona, nkhawa, kutopa, komanso kuuma m'mawa kwa anthu omwe ali ndi fibromyalgia.
  • Zizindikiro za kusamba. Kafukufuku woyambirira akuwonetsa kuti kutenga 150 mg ya 5-HTP tsiku lililonse kwa milungu inayi sikuchepetsa kuchepa kwa azimayi omwe amabwera kumapeto kwa nthawi.
  • Migraine. Umboni pazotsatira za 5-HTP popewa kapena kuchiza mutu waching'alang'ala mwa akulu sadziwika. Kafukufuku wina akuwonetsa kuti kutenga 5-HTP tsiku lililonse sikuchepetsa mutu waching'alang'ala, pomwe maphunziro ena akuwonetsa kuti zitha kukhala zopindulitsa monga mankhwala akuchipatala. 5-HTP sikuwoneka ngati ichepetsa migraines mwa ana.
  • Kunenepa kwambiri. Kafukufuku woyambirira akuwonetsa kuti kutenga 5-HTP kumathandizira kuchepetsa kudya, kudya kwama caloriki, ndi kulemera kwa anthu onenepa kwambiri. Kafukufuku wina akuwonetsa kuti kugwiritsa ntchito mankhwala opopera mkamwa omwe ali ndi 5-HTP ndi zina zotulutsa (5-HTP-Nat Exts, Medestea Biotech Sp, Torino, Italy) kwa milungu inayi kumawonjezera kuchepa kwa thupi pafupifupi 41% mwa azimayi onenepa kwambiri omwe atha msambo.
  • Kusiya heroin, morphine, ndi mankhwala ena opioid. Kafukufuku woyambirira akuwonetsa kuti kutenga 200 mg ya 5-HTP tsiku lililonse kwa masiku 6 limodzi ndi tyrosine, phosphatidylcholine, ndi L-glutamine, kumatha kuchepetsa kugona ndi zizindikiritso zakutha pakubwezeretsa omwe adayamba kugwiritsa ntchito heroin.
  • Matenda a Parkinson. Kafukufuku woyambirira akuwonetsa kuti kutenga 100-150 mg ya 5-HTP pakamwa tsiku lililonse ndi mankhwala wamba kumawoneka kuti kumachepetsa kugwedezeka, koma maubwino awa amangopitilira kwa miyezi isanu. Kafukufuku wina woyambirira akuwonetsa kuti kutenga 50 mg ya 5-HTP tsiku lililonse kumatha kuchepetsa zizindikilo za kusuntha kwa mankhwala a levodopa, komanso zizindikilo za kukhumudwa, mwa anthu omwe ali ndi matenda a Parkinson. Koma kumwa kwambiri 5-HTP, 275-1500 mg tsiku lililonse, komanso carbidopa kumatha kukulitsa zizindikilo zina.
  • Kupweteka mutu. Kafukufuku woyambirira akuwonetsa kuti kutenga 100 mg ya 5-HTP katatu tsiku lililonse kwa masabata a 8 sikuchepetsa kupweteka kapena kutalika kwa mavuto am'mutu.
  • Matenda a chidwi-kuchepa kwa matenda (ADHD).
  • Kusowa tulo.
  • Matenda a Premenstrual dysphoric (PMDD).
  • Matenda a Premenstrual (PMS).
  • Matenda a Ramsey-Hunt.
  • Zochitika zina.
Umboni wina umafunika kuti muwonetsetse momwe 5-HTP imagwirira ntchito.

5-HTP imagwira ntchito muubongo ndi pakatikati mwa manjenje powonjezera kupanga mankhwala a serotonin. Serotonin imatha kukhudza kugona, kulakalaka, kutentha, machitidwe ogonana, komanso kumva kupweteka. Popeza 5-HTP imawonjezera kaphatikizidwe ka serotonin, imagwiritsidwa ntchito pamavuto angapo pomwe serotonin imakhulupirira kuti imagwira ntchito yofunika kuphatikiza kukhumudwa, kugona tulo, kunenepa kwambiri, ndi zina zambiri.

Mukamamwa: 5-HTP ndi WOTSATIRA BWINO mukamamwa moyenera. Amagwiritsidwa ntchito mosamala mpaka 400 mg tsiku lililonse mpaka chaka chimodzi. Koma anthu ena omwe atenga 5-HTP adwala matenda otchedwa eosinophilia-myalgia syndrome (EMS). EMS ndi vuto lalikulu lomwe limakhudza kufinya kwambiri kwa minofu (myalgia) ndi zovuta zamwazi (eosinophilia). Anthu ena amaganiza kuti EMS ikhoza kuyambitsidwa ndi chochitika mwangozi kapena choipitsa muzinthu zina za 5-HTP. Koma palibe umboni wokwanira wa sayansi wodziwa ngati EMS imayambitsidwa ndi 5-HTP, yonyansa, kapena chinthu china. Mpaka zambiri zidziwike, 5-HTP iyenera kugwiritsidwa ntchito mosamala.

Zotsatira zina zoyipa za 5-HTP ndi monga kutentha pa chifuwa, kupweteka m'mimba, nseru, kusanza, kutsegula m'mimba, kugona, mavuto azakugonana, komanso mavuto am'mimba.

5-HTP ndi ZOTSATIRA ZOSATETEZEKA akamamwa pakamwa mokwanira. Mlingo wochokera ku 6-10 magalamu tsiku lililonse walumikizidwa ndi mavuto am'mimba komanso kupindika kwa minofu.

Chenjezo lapadera & machenjezo:

Mimba ndi kuyamwitsa: Palibe zodalirika zokwanira kudziwa ngati 5-HTP ndiyabwino kugwiritsa ntchito mukakhala ndi pakati kapena poyamwitsa. Khalani otetezeka ndikupewa kugwiritsa ntchito.

Ana: 5-HTP ndi WOTSATIRA BWINO akamamwa moyenera. Mlingo wa 5 mg / kg tsiku lililonse wagwiritsidwa ntchito mosamala kwa zaka zitatu mwa makanda ndi ana mpaka wazaka 12. Monga momwe zimakhalira ndi achikulire, palinso nkhawa yokhudza kuthekera kwa eosinophilia-myalgia syndrome (EMS) mwa ana, vuto lalikulu lomwe limakhudza kufinya kwambiri kwa minofu (myalgia) komanso kusokonekera kwa magazi (eosinophilia).

Opaleshoni: 5-HTP imatha kukhudza mankhwala aubongo otchedwa serotonin. Mankhwala ena operekedwa panthawi yochita opaleshoni amathanso kukhudza serotonin. Kutenga 5-HTP musanachite opaleshoni kumatha kubweretsa serotonin yochulukirapo muubongo ndipo kumatha kubweretsa zovuta zoyipa kuphatikiza mavuto amtima, kunjenjemera, komanso kuda nkhawa. Uzani odwala kuti asiye kumwa 5-HTP osachepera masabata awiri asanachitike opaleshoni.

Zazikulu
Musatenge kuphatikiza uku.
Mankhwala a kukhumudwa (MAOIs)
5-HTP imawonjezera mankhwala mu ubongo otchedwa serotonin. Mankhwala ena omwe amagwiritsidwa ntchito pakukhumudwitsanso amachulukitsa serotonin. Kutenga 5-HTP ndi mankhwalawa omwe amagwiritsidwa ntchito pakukhumudwa kumatha kukulitsa serotonin kwambiri. Izi zitha kuyambitsa zovuta zoyipa kuphatikiza kupweteka kwa mutu, mavuto amtima, kunjenjemera, kusokonezeka, komanso kuda nkhawa.

Ena mwa mankhwala omwe amagwiritsidwa ntchito pakukhumudwa ndi monga phenelzine (Nardil), tranylcypromine (Parnate), ndi ena.
Wamkati
Samalani ndi kuphatikiza uku.
Carbidopa (Lodosyn)
5-HTP imatha kukhudza ubongo. Carbidopa (Lodosyn) amathanso kukhudza ubongo. Kutenga 5-HTP limodzi ndi carbidopa kumatha kuonjezera chiopsezo cha zovuta zoyipa kuphatikiza kuyankhula mwachangu, nkhawa, kukwiya, ndi ena.
Mankhwala osokoneza bongo (CNS depressants)
5-HTP ikhoza kuyambitsa tulo ndi kugona. Mankhwala omwe amachititsa kuti anthu azigona tulo amatchedwa mankhwala ogonetsa. Kutenga 5-HTP limodzi ndi mankhwala osokoneza bongo kumatha kubweretsa kugona kwambiri.

Mankhwala ena ogonetsa monga clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), ndi ena.
Mankhwala a Serotonergic
5-HTP ikhoza kuonjezera mankhwala mu ubongo otchedwa serotonin. Mankhwala ena amachulukitsanso serotonin. Kutenga 5-HTP limodzi ndi mankhwalawa kumatha kukulitsa serotonin kwambiri. Izi zitha kuyambitsa zovuta zoyipa kuphatikiza kupweteka kwa mutu, mavuto amtima, kunjenjemera, kusokonezeka, komanso kuda nkhawa.

Zina mwa mankhwalawa ndi monga fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Tofranil), sumatriptan (Imitrex), zolmitriptan (Zomig), rizatriptan methadone (Dolophine), tramadol (Ultram), ndi ena ambiri.
Zitsamba ndi zowonjezera zowonjezera
5-HTP imatha kuyambitsa tulo kapena kugona. Kuigwiritsa ntchito limodzi ndi zitsamba zina ndi zowonjezera zomwe zimakhala ndi vuto lomwelo zimatha kugona kwambiri. Zina mwa zitsamba ndi zowonjezerazi ndi monga calamus, California poppy, catnip, hop, Jamaican dogwood, kava, St. John's wort, skullcap, valerian, yerba mansa, ndi ena.
Zitsamba ndi zowonjezera ndi serotonergic katundu
5-HTP imawonjezera ubongo wamagulu otchedwa serotonin. Kutenga 5-HTP pamodzi ndi zitsamba zina ndi zowonjezera zomwe zimakulitsa serotonin zitha kubweretsa serotonin yochulukirapo ndipo zimayambitsa zovuta zina kuphatikiza mavuto amtima, kunjenjemera komanso kuda nkhawa. Zitsamba zina ndi zowonjezera zomwe zimawonjezera kuchuluka kwa serotonin ndi za ku Hawaii baby woodrose, L-tryptophan, S-adenosylmethionine (SAMe), ndi St. John's wort.
Palibe zochitika zodziwika ndi zakudya.
Mlingo wotsatira udaphunziridwa pakufufuza kwasayansi: ACHIKULU

NDI PAKAMWA:
  • Matenda okhumudwa: Kawirikawiri, 150-800 mg tsiku lililonse amatengedwa kwa masabata 2-6. Mankhwalawa nthawi zina amagawanika ndikugwiritsidwa ntchito ngati 50 mg mpaka 100 mg katatu patsiku. Nthawi zina mlingowo umayamba kutsika ndipo umachulukirachulukira pakadutsa milungu 1-2 mpaka mulingo wofuna kukwaniritsa. Nthawi zambiri, mankhwala apamwamba amagwiritsidwa ntchito. Mu kafukufuku wina, mlingowo umakulirakulira mpaka magalamu atatu patsiku.
2-Amino-3- (5-Hydroxy-1H-Indol-3-yl) Propanoic Acid, 5 Hydroxy-Tryptophan, 5 Hydroxy-Tryptophane, 5-Hydroxytryptophan, 5-Hydroxytryptophane, 5-Hydroxy L-Tryptophan, 5-Hydroxy L-Tryptophane, 5-Hydroxy Tryptophan, 5-L-Hydroxytryptophan, L-5 HTP, L-5-Hydroxytryptophan, L-5-Hydroxytryptophane, Oxitriptan.

Kuti mudziwe zambiri za momwe nkhaniyi idalembedwera, chonde onani Mankhwala Achilengedwe Pazonse njira.


  1. Meloni M, Puligheddu M, Sanna F, ndi al. Kuchita bwino ndi chitetezo cha 5-Hydroxytryptophan pamavuto obwera chifukwa cha levodopa mu matenda a Parkinson: Kupeza koyambirira. J Neurol Sci. Chidwi. 2020; 415: 116869. Onani zenizeni.
  2. Yousefzadeh F, Sahebolzamani E, Sadri A, ndi al. 5-Hydroxytryptophan ngati mankhwala othandizira pochiza matenda osokoneza bongo: kuyesedwa kosawona kawiri komwe kumayang'aniridwa ndi placebo. Int Chipatala cha Psychopharmacol. Chikhulupiriro. 2020; 35: 254-262. Onani zenizeni.
  3. Javelle F, Lampit A, Bloch W, Häussermann P, Johnson SL, Zimmer P.Zotsatira za 5-hydroxytryptophan pamitundu yosiyanasiyana ya kukhumudwa: kuwunika mwatsatanetsatane ndikuwunika meta. Zakudya Rev 2020; 78: 77-88. Onani zenizeni.
  4. Meloni M, Puligheddu M, Carta M, Cannas A, Figorilli M, Defazio G. Kuchita bwino ndi chitetezo cha 5-hydroxytryptophan pa kukhumudwa ndi mphwayi mu matenda a Parkinson: chiyambi choyambirira. Mphatso J Neurol 2020; 27: 779-786. Onani zenizeni.
  5. Israelyan N, Del Colle A, Li Z, ndi al. Zotsatira za Serotonin ndi Slow-Release 5-Hydroxytryptophan pa Kutuluka kwa m'mimba mu Model ya Kukhumudwa. Gastroenterology. 2019; 157: 507-521 (Adasankhidwa) Onani zenizeni.
  6. Michelson D, Tsamba SW, Casey R, et al. Matenda okhudzana ndi eosinophilia-myaligia okhudzana ndi kukhudzana ndi l-5-hydroxytryptophan. J Rheumatol. 1994; 21: 2261-5 (Pamasamba) Onani zenizeni.
  7. Lemaire PA, Adosraku RK. Njira ya HPLC yoyeserera molunjika kwa serotonin preursor, 5-hydroxytrophan, m'mbeu za Griffonia simplicifolia. Phytochem Anal 2002; 13: 333-7. Onani zowoneka.
  8. Rondanelli M, Opizzi A, Faliva M, Bucci M, Perna S. Ubale pakati pa kuyamwa kwa 5-hydroxytryptophan kuchokera pachakudya chophatikizika, pogwiritsa ntchito Griffonia simplicifolia yotulutsa, komanso momwe zimakhudzira azimayi onenepa kwambiri pambuyo poyamwa pakamwa. Idyani Disord Weight 2012; 17: e22-8. Onani zenizeni.
  9. Zowonjezera Mania kutsatira kuwonjezera kwa hydroxytryptophan ku monoamine oxidase inhibitor. Gen Hosp Psychiatry 2012; 34: 102.e13-4.
  10. Chen D, Liu Y, He W, Wang H, Wang Z.Neurotransmitter-precursor-precursor-supplemental for for detoxified heroin osokoneza. J Huazhong Univ Sci Technolog Med Sci. 2012; 32: 422-7.
  11. Gendle MH, Young EL, Romano AC. Zotsatira zakumlomo kwa 5-hydroxytryptophan pamalingaliro okhazikika: kuzindikira momwe kuthekera kolumikizirana kwa dopamine / serotonin mtsogolo. Hum Psychopharmacol. 2013; 28: 270-3. (Adasankhidwa)
  12. Msonkhano wa Komiti Yolangiza ya Pharmacy Compounding Adviceory June 17-18, 2015. Ipezeka pa: www.fda.gov/downloads/advisorycommittee/committeemeetingmaterials/drugs/pharmacycompoundingadvisorycommittee/ucm455276.pdf (yopezeka pa 8/21/15).
  13. Ulamuliro wa Zakudya ndi Mankhwala ku U.S. Mayiko amasiye ndi kuvomereza. Ipezeka pa: www.accessdata.fda.gov/script/opdlisting/oopd/index.cfm (yopezeka pa 8/20/2015).
  14. Das YT, Bagchi M, Bagchi D, Preuss HG. (Adasankhidwa) Chitetezo cha 5-hydroxy-L-tryptophan. Toxicol Lett. 2004; 150: 111-22. (Adasankhidwa) Onani zenizeni.
  15. Weise P, Koch R, Shaw KN, Rosenfeld MJ. Kugwiritsa ntchito 5-HTP pochiza matenda a Down's syndrome. Matenda 1974; 54165-8. Onani zenizeni.
  16. Bazelon M, Paine RS, Cowie VA, ndi al. Kusintha kwa hypotonia mwa makanda omwe ali ndi Down's syndrome poyendetsa 5-hydroxytryptophan. Lancet 1967; 1: 1130-3. Onani zenizeni.
  17. Sano I. Chithandizo cha kukhumudwa ndi L-5-hydroxytryptophan (L-5-HTP). Psychiatria et Neurologia Japonicas 1972; 74: 584 (Pamasamba)
  18. Klein P, Lees A, ndi Stern G. Zotsatira zakusowa kwa 5-hydroxytryptophan pakukhala kosasunthika kwa parkinsonia kochita zinthu moyenera komanso pamavuto ena amitsempha. Adv Advol 1986; 45: 603-604.
  19. VanPraag, H. M. ndi Korf, J. 5-Hydroxytryptophan monga antidepressant: Mtengo wolosera zamayeso a probenecid. Psychopharmacol Ng'ombe. 1972; 8: 34-35.
  20. Sicuteri F. 5-hydroxytryptophan mu prophylaxis ya migraine. Kulumikizana Kwama Pharmacological 1972; 4: 213-218.
  21. Rosano Burgio, F., Borgatti, R., Scarabello, E., ndi Lanzi, G. Kumutu kwa ana ndi achinyamata. Kukula kwa Msonkhano Woyamba Wapadziko Lonse Womvera Mutu mu Ana ndi Adolecents. 1989; 339-47.
  22. Mathew NT. 5-hydroxytryptophan mu prophylaxis ya migraine: kafukufuku wakhungu kawiri. Mutu 1978; 18: 111.
  23. De Benedittis G, Massei R. 5-HT otsogolera ku migraine prophylaxis: kafukufuku wopunduka ndi L-5-hydroxytryptophan. Kliniki J Pain 1986; 2: 123-129.
  24. Wyatt, R. J., Vaughan, T., Kaplan, J., Galanter, M., ndi Green, R. 5-Hydroxytryptophan ndi matenda osachiritsika a schizophrenia. Mu: Barchas J ndi Usdin E. Serotonin ndi Khalidwe. New York: Atolankhani Acedemic; 1973.
  25. Brodie HKH, Sack R, ndi Siever L. Clinical maphunziro a L-5-hydroxytryptophan pakukhumudwa. Mu: Barchas J ndi Usdin E. Serotonin ndi machitidwe. New York: Atolankhani Ophunzirira; 1973.
  26. Auffret, M., Comte, H., ndi Bene, J. Eosinophilia-myalgia matenda opangidwa ndi L-5 hydroxytryptophane: pafupifupi milandu itatu. Fund Clin Pharmacol 2013; Suppl 1: chithunzi P2-204.
  27. Cangiano C, Laviano A, Del Ben M, ndi al. Zotsatira zamkamwa 5-hydroxy-tryptophan pakudya mphamvu ndi kusankha kwa macronutrient mwa odwala matenda ashuga osadalira insulin. Int J Obes Relat Metab Disord 1998; 22: 648-54. Onani zenizeni.
  28. Ju, C.Y. ndi Tsai, C. T. Serotonergic njira zomwe zimakhudza kuponderezana kwa kudya ndi 5-HTP mu makoswe. Chin J Physiol 1995; 38: 235-240 (Pamasamba) Onani zenizeni.
  29. Pranzatelli, M. R., Tate, E., Galvan, I., ndi Wheeler, A. Kuyesedwa koyesedwa kwa 5-hydroxy-L-tryptophan ya ataxia mu khunyu ya myoclonus yomwe ikupita patsogolo. Clin Neurol. Neurosurg. 1996; 98: 161-164 (Pamasamba) Onani zenizeni.
  30. Frith, C. D., Johnston, E. C., Joseph, M.H, Powell, R. J., ndi Watts, R. W. Kuyesedwa kwamaso akhungu awiri a 5-hydroxytryptophan pankhani ya matenda a Lesch- Nyhan. J Neurol Neurosurg. Kusokoneza maganizo 1976; 39: 656-662. Onani zenizeni.
  31. Bastard, J., Truelle, J. L., ndi Emile, J. [Mphamvu ya 5 hydroxy-tryptophan mu matenda a Parkinson]. Nouv Wolemba Med 9-11-1976; 5: 1836-1837. Onani zenizeni.
  32. Trouillas P, Serratrice G, Laplane D, ndi al. Mawonekedwe opangira ma 5-hydroxytryptophan mu ataxia ya Friedreich. Zotsatira za kafukufuku wothandizana ndi mankhwala osokoneza bongo osawona. Mzere Neurol 1995; 52: 456-60. Onani zenizeni.
  33. Wessel K, Hermsdörfer J, Deger K, ndi al. Kuphunzira kawiri kosawona ndi mawonekedwe a hydroxytryptophan mwa odwala omwe ali ndi matenda opatsirana a cerebellar. Mzere Neurol 1995; 52: 451-5. Onani zenizeni.
  34. Alino, J. J., Gutierrez, J. L., ndi Iglesias, M. L. 5-Hydroxytryptophan (5-HTP) ndi MAOI (nialamide) pochiza zokhumudwitsa. Kafukufuku wowongoleredwa wakhungu kawiri. Int Pharmacopsychiatry 1976; 11: 8-15 (Pamasamba) Onani zenizeni.
  35. Pranzatelli, M. R., Tate, E., Huang, Y., Haas, R. H., Bodensteiner, J., Ashwal, S., ndi Franz, D. Neuropharmacology ya myoclonus khunyu wopita patsogolo: kuyankha kwa 5- hydroxy-L-tryptophan. Khunyu 1995; 36: 783-791. Onani zenizeni.
  36. Thomson, J., Rankin, H., Ashcroft, GW, Yates, CM, McQueen, JK, ndi Cummings, SW Chithandizo cha kukhumudwa pazochitika zambiri: kuyerekezera L- tryptophan, amitriptyline, komanso kuphatikiza kwa L-tryptophan ndi amitriptyline ndi placebo. Psychol Med 1982; 12: 741-751 (Pamasamba) Onani zenizeni.
  37. Trouillas, P., Garde, A., Robert, JM, Renaud, B., Adeleine, P., Bard, J., ndi Brudon, F. [Kugonjetsedwa kwa matenda a cerebellar omwe akuyang'aniridwa kwa nthawi yayitali 5-HTP kapena kuphatikiza kwa 5-HTP ndi benserazide. Milandu ya 26 yotsimikizidwa ndikuchiritsidwa pogwiritsa ntchito njira zamakompyuta]. Rev Neurol. (Paris) 1982; 138: 415-435 (Pamasamba) Onani zenizeni.
  38. Thal, L. J., Sharpless, N. S., Wolfson, L., ndi Katzman, R. Chithandizo cha myoclonus ndi L-5-hydroxytryptophan ndi carbidopa: kuwunika kwazachipatala, zamagetsi, komanso zamagetsi. Ann Neurol. 1980; 7: 570-576. Onani zenizeni.
  39. van Hiele LJ. l-5-Hydroxytryptophan mu kukhumudwa: mankhwala oyamba m'malo mwa zamisala? Chithandizo cha odwala 99 omwe ali ndi vuto la 'mankhwala osagwira'. Neuropsychobiology 1980; 6: 230-40. (Adasankhidwa) Onani zenizeni.
  40. Magnussen, ine.ndi Nielsen-Kudsk, F. Bioavailability ndi ma pharmacokinetics ofanana ndi omwe amapatsidwa L-5-hydroxytryptophan pakamwa pokhazikika. Acta Pharmacol Toxicol. (Copenh) 1980; 46: 257-262 (Adasankhidwa) Onani zenizeni.
  41. Trouillas, P., Garde, A., Robert, J. M., ndi Adeleine, P. [Kuponderezedwa kwa cerebellar ya anthu ataxia motsogozedwa ndi 5-hydroxytryptophan kwa nthawi yayitali]. CR Maonekedwe Acad Sci III 1-5-1981; 292: 119-122. Onani zenizeni.
  42. Pueschel SM, Reed RB, Cronk CE, Goldstein BI. 5-hydroxytryptophan ndi pyridoxine. Zotsatira zawo kwa ana aang'ono omwe ali ndi Down's syndrome. Ndine J Dis Mwana 1980; 134: 838-44. Onani zenizeni.
  43. Longo G, Rudoi I, Iannuccelli M, Strinati R, Panizon F. [Chithandizo cha mutu wofunikira pazaka zokula ndi L-5-HTP (yambirani kafukufuku wakhungu kawiri motsutsana ndi placebo)]. Wodwala Med Chir 1984; 6: 241-5. Onani zenizeni.
  44. Bono, G., Micieli, G., Sances, G., Calvani, M., ndi Nappi, G. L-5HTP chithandizo cham'mutu wam'mutu: kuyesa kuzindikira odwala omwe akumvera. Cephalalgia 1984; 4: 159-165 (Pamasamba) Onani zenizeni.
  45. Quadbeck, H., Lehmann, E., ndi Tegeler, J. Kuyerekeza kwa zomwe zimayambitsa kupsinjika kwa tryptophan, tryptophan / 5- hydroxytryptophan kuphatikiza ndi nomifensine. Neuropsychobiology 1984; 11: 111-115 (Pamasamba) Onani zenizeni.
  46. van Praag, H. M. Pofufuza momwe magwiridwe anthawi zonse amagwirira ntchito: 5-HTP / tyrosine zosakanikirana pakukhumudwa. Adv Biochem Psychopharmacol. 1984; 39: 301-314 (Pamasamba) Onani zenizeni.
  47. Trouillas P. Kugonjetsedwa kwa matenda a cerebellar okhala ndi nthawi yayitali yoyendetsa 5-HTP kapena kuphatikiza kwa 5-HTP-benserazide: Milandu 21 yokhala ndi zizindikiritso zomwe zimakonzedwa ndi kompyuta. Ital J Neurol Sci. 1984; 5: 253-266. Onani zenizeni.
  48. van Praag, H. M. ndi de Haan, S. Chemoprophylaxis wazokhumudwitsa. Kuyesa kuyerekeza lifiyamu ndi 5- hydroxytryptophan. Acta Psychiatr. Scand Suppl 1981; 290: 191-201. Onani zenizeni.
  49. van Praag, H. ndi de Hann, S. Kukhumudwa koopsa ndi 5-hydroxytryptophan prophylaxis. Kupuma kwa Psychiatry. 1980; 3: 75-83. Onani zenizeni.
  50. Soulairac, A. [Hypnotic zochita za mecloqualone. Kuyerekeza ndi zotsatira za placebo ndi secobarbital]. Onetsani Med 4-10-1971; 79: 817-818. Onani zenizeni.
  51. Chase, T. N., Ng, L. K., ndi Watanabe, matenda a A. M. Parkinson. Kusinthidwa ndi 5-hydroxytryptophan. Neurology. 1972; 22: 479-484. (Adasankhidwa) Onani zenizeni.
  52. Wyatt, R. J., Vaughan, T., Galanter, M., Kaplan, J., ndi Green, R. Kusintha kwamakhalidwe a odwala matenda a schizophrenic omwe apatsidwa L-5- hydroxytryptophan. Sayansi 9-22-1972; 177: 1124-1126. Onani zenizeni.
  53. van Praag HM, Korf J, Dols LC, Schut T. Kafukufuku woyendetsa ndege wonena za kuyerekezera kwamayeso a probenecid pogwiritsa ntchito 5-hydroxytryptophan ngati antidepressant. Psychopharmacologia. 1972; 25: 14-21. Onani zenizeni.
  54. Zarcone, V., Kales, A., Scharf, M., Tan, T. L., Simmons, J. Q., ndi Dement, W. C. Kubwereza kwamlomo kwa 5-hydroxytryptophan. Zomwe zimakhudza machitidwe ndi magonedwe mu ana awiri amisala. Arch Gen Psychiatry 1973; 28: 843-846 (Pamasamba) Onani zenizeni.
  55. Chadwick, D., Hallett, M., Harris, R., Jenner, P., Reynolds, EH, ndi Marsden, CD Clinical, biochemical, ndi thupi zomwe zimasiyanitsa myoclonus yomwe imayankha 5-hydroxytryptophan, tryptophan yokhala ndi monoamine oxidase inhibitor, ndi clonazepam. Ubongo 1977; 100: 455-487. Onani zenizeni.
  56. Van Woert, M.H, Rosenbaum, D., Howieson, J., ndi Bowers, M. B., Jr. chithandizo chanthawi yayitali cha myoclonus ndi matenda ena amitsempha ndi L-5- hydroxytryptophan ndi carbidopa. N Engl J Med 1-13-1977; 296: 70-75. Onani zenizeni.
  57. Nolen WA, van de Putte JJ, Dijken WA, Kamp JS. L-5HTP pakukhumudwa komwe kumagonjetsedwa ndi ma inhibitors obwezeretsanso. Phunziro lofananira lotseguka ndi tranylcypromine. Br J Psychiatry 1985; 147: 16-22. Onani zenizeni.
  58. De Benedittis G, Massei R. Serotonin otsogola pamutu wamutu woyamba. Kafukufuku wowonera wakhungu ndi L-5-hydroxytryptophan vs. placebo. J Neurosurg Sci 1985; 29: 239-48 (Pamasamba) Onani zenizeni.
  59. Titus F, Dávalos A, Alom J, Codina A. 5-Hydroxytryptophan motsutsana ndi methysergide mu prophylaxis ya migraine. Kuyesedwa kwamankhwala mwachisawawa. Eur Neurol. 1986; 25: 327-9 (Pamasamba) Onani zenizeni.
  60. Santucci M, Cortelli P, Rossi PG, Baruzzi A, Sacquegna T.L-5-hydroxytryptophan motsutsana ndi placebo muubwana wa migraine prophylaxis: kafukufuku wachiwiri wakhungu. Cephalalgia 1986; 6: 155-7 (Pamasamba) Onani zenizeni.
  61. Irwin, M. R., Marder, S. R., Fuentenebro, F., ndi Yuwiler, A. L-5-hydroxytryptophan imachepetsa zizindikiritso zabwino zama psychotic zopangidwa ndi D-amphetamine. Kupuma kwa Psychiatry. 1987; 22: 283-289. Onani zenizeni.
  62. Angst J, Woggon B, Schoepf J. Chithandizo cha kukhumudwa ndi L-5-hydroxytryptophan motsutsana ndi imipramine. Zotsatira zamaphunziro awiri otseguka komanso osawona kawiri. Arch Psychiatr Nervenkr 1977; 224: 175-86. Onani zenizeni.
  63. Kahn RS, Westenberg HG, Verhoeven WM, ndi al. Zotsatira za zomwe zimayambitsanso serotonin ndikutenga inhibitor pamavuto; kuyerekezera kosawona kwa 5-hydroxytryptophan, clomipramine ndi placebo. Int Clin Psychopharmacol. 1987; 21: 33-45. (Adasankhidwa) Onani zenizeni.
  64. De Giorgis G, Miletto R, Iannuccelli M, Camuffo M, Scerni S. Mutu polumikizana ndi zovuta za kugona mwa ana: kuwunika kwa psychodiagnostic ndikuwongolera maphunziro azachipatala - L-5-HTP motsutsana ndi placebo. Mankhwala Osokoneza Bongo a 1987; 13: 425-33. Onani zenizeni.
  65. Zmilacher, K., Battegay, R., ndi Gastpar, M. L-5-hydroxytryptophan okha komanso kuphatikiza ndi zotumphukira za decarboxylase inhibitor pochiza kukhumudwa. Neuropsychobiology 1988; 20: 28-35 (Pamasamba) Onani zenizeni.
  66. Nolen, W. A., van de Putte, J. J., Dijken, W. A., Kamp, J. S., Blansjaar, B. A., Kramer, H. J., ndi Haffmans, J. Njira yothandizira pakukhumudwa. II. MAO inhibitors mu kukhumudwa kosagwirizana ndi ma cyclic antidepressants: maphunziro awiri olamulidwa ndi tranylcypromine motsutsana ndi L-5-hydroxytryptophan ndi nomifensine. Acta Psychiatr. Mzere 1988; 78: 676-683. Onani zenizeni.
  67. Kaneko M, Kumashiro H, Takahashi Y, Hoshino Y. L-5HTP chithandizo ndi seramu 5-HT mulingo pambuyo pa L-5-HTP kutsitsa kwa odwala omwe ali ndi nkhawa. Neuropsychobiology 1979; 5: 232-40. Onani zenizeni.
  68. Rousseau JJ. Zotsatira za kuphatikiza kwa levo-5-hydroxytryptophan-dihydroergocristine pakukhumudwa komanso magwiridwe antchito a neuropsychic: kuyesedwa kwamankhwala osawona kawiri kwa odwala okalamba. Kliniki Ther 1987; 9: 267-72. Onani zenizeni.
  69. Anders, T. F., Cann, H. M., Ciaranello, R. D., Barchas, J. D., ndi Berger, P. A. Zowunikiranso zina zakugwiritsa ntchito 5-hydroxytryptophan mwa mwana yemwe ali ndi matenda a Lesch-Nyhan. Neuropadiatrie. 1978; 9: 157-166. Onani zenizeni.
  70. Ceci F, Cangiano C, Cairella M, et al. (Adasankhidwa) Zotsatira zakulankhula pakamwa 5-hydroxytryptophan pakudyetsa machitidwe azambiri zazimayi zazikulu kwambiri. J Neural Transm. 1989; 76: 109-17 (Pamasamba) Onani zenizeni.
  71. Jangid P, Malik P, Singh P, Sharma M, Gulia AK. Kuyerekeza kuyerekezera mphamvu ya l-5-hydroxytryptophan ndi fluoxetine mwa odwala omwe amakhala ndi vuto loyamba lokhumudwitsa. Asia J Psychiatr 2013; 6: 29-34. Onani zenizeni.
  72. Zarcone, V. P., Jr. ndi Hoddes, E. Zotsatira za 5-hydroxytryptophan pakugawika kwa REM kugona mwa zidakwa. Ndine J Psychiatry 1975; 132: 74-76. Onani zenizeni.
  73. Opladen, T., Hoffmann, G. F., ndi Blau, N. Kafukufuku wapadziko lonse lapansi wa odwala omwe ali ndi zofooka za tetrahydrobiopterin omwe ali ndi hyperphenylalaninaemia. J Cholowa. Metab Dis 2012; 35: 963-973. Onani zenizeni.
  74. Baraldi, S., Hepgul, N., Mondelli, V., ndi Pariante, C. M. Syndromeomatic treatment of interferon-alpha-induced depression in hepatitis C: kuwunika mwatsatanetsatane. J Chipatala cha Psychopharmacol. 2012; 32: 531-543. Onani zenizeni.
  75. Pan, L., McKain, BW, Madan-Khetarpal, S., Mcguire, M., Diler, RS, Perel, JM, Vockley, J., ndi Brent, kusowa kwa DA GTP-cyclohydrolase kumayankha sapropterin ndi 5-HTP supplementation : mpumulo wa kukhumudwa chifukwa chamankhwala komanso kudzipha. Mlandu wa BMJ. 2011; 2011 Onani zolemba.
  76. Friedman, J., Roze, E., Abdenur, JE, Chang, R., Gasperini, S., Saletti, V., Wali, GM, Eiroa, H., Neville, B., Felice, A., Parascandalo,. R., Zafeiriou, DI, Arrabal-Fernandez, L., Dill, P., Eichler, FS, Echenne, B., Gutierrez-Solana, LG, Hoffmann, GF, Hyland, K., Kusmierska, K., Tijssen,. MA, Lutz, T., Mazzuca, M., Penzien, J., Poll-The BT, Sykut-Cegielska, J., Szymanska, K., Thony, B., ndi Blau, N. Sepiapterin reductase kusowa: kuchiritsidwa kutsanzira kwa ziwalo za ubongo. Ann Neurol. 2012; 71: 520-530. Onani zenizeni.
  77. Jukic T, Rojc B, Boben-Bardutzky D, Hafner M, Ihan A. Kugwiritsa ntchito chowonjezera chakudya ndi D-phenylalanine, L-glutamine ndi L-5-hydroxytriptophan pothana ndi zizolowezi zochotsa mowa. Coll Antropol 2011; 35: 1225-30. (Adasankhidwa) Onani zenizeni.
  78. Sarris, J. Matenda okhumudwa: njira yothandizirana yothandizirana ndi othandizira. Njira ina.Health Med. 2011; 17: 26-37. Onani zenizeni.
  79. Dill, P., Wagner, M., Somerville, A., Thony, B., Blau, N., ndi Weber, P. Neurology ya ana: kuuma kwa paroxysmal, kuyang'ana mmwamba, ndi hypotonia: zizindikiritso za kuchepa kwa sepiapterin reductase. Neurology 1-31-2012; 78: e29-e32. Onani zenizeni.
  80. Horvath, GA, Selby, K., Poskitt, K., Hyland, K., Waters, PJ, Coulter-Mackie, M., ndi Stockler-Ipsiroglu, SG Hemiplegic migraine, khunyu, kupita patsogolo kwa spastic paraparesis, kusokonezeka kwa malingaliro, ndi kukomoka mwa abale ndi serotonin yotsika. Cephalalgia 2011; 31: 1580-1586 (Pamasamba) Onani zenizeni.
  81. Morrison, K. E. Kugwiritsa ntchito ma genome athunthu kumadziwitsa chithandizo: mankhwala omwe mwakukonda kwanu amatenga gawo lina kupita patsogolo. Kliniki Chem 2011; 57: 1638-1640. Onani zenizeni.
  82. Bainbridge, MN, Wiszniewski, W., Murdock, DR, Friedman, J., Gonzaga-Jauregui, C., Newsham, I., Reid, JG, Fink, JK, Morgan, MB, Gingras, MC, Muzny, DM, Hoang, LD, Yousaf, S., Lupski, JR, ndi Gibbs, RA Kugwiritsa ntchito ma genome onse oyendetsera bwino odwala. Sayansi Yotanthauzira. Med 6-15-2011; 3: 87re3. Onani zenizeni.
  83. den Boer JA, Westenberg HG. Khalidwe, neuroendocrine, ndi biochemical zotsatira za 5-hydroxytryptophan administration mu mantha mantha. Psychiatry Res 1990; 31: 267-78 (Pamasamba) Onani zenizeni.
  84. Adamsen, D., Meili, D., Blau, N., Thony, B., ndi Ramaekers, V. Autism yolumikizidwa ndi asidi wotsika wa 5-hydroxyindolacetic mu CSF ndi heterozygous SLC6A4 gene Gly56Ala kuphatikiza 5-HTTLPR L / L . Mol.Genet.Metab 2011; 102: 368-373. Onani zenizeni.
  85. Cross, D. R., Kellermann, G., McKenzie, L. B., Purvis, K. B., Hill, G. J., ndi Huisman, H. Chithandizo chamankhwala cha amino acid chokhala ndi ana omwe ali pachiwopsezo. Zaumoyo Wosamalira Ana. 2011; 37: 671-678. Onani zenizeni.
  86. Gendle, M.H ndi Golding, A. C. Kuyang'anira pakamwa kwa 5-hydroxytryptophan (5-HTP) kumapangitsa kuti zisankho zisamayende bwino koma osati pachiwopsezo: umboni wochokera ku Iowa Gask Task. Hum Psychopharmacol. 2010; 25: 491-499. Onani zenizeni.
  87. Iovieno, N., Dalton, E. D., Fava, M., ndi Mischoulon, D. Wachiwiri-tier antidepressants achilengedwe: kuwunikanso ndikuwunika. J Zimakhudza Kusokonezeka. 2011; 130: 343-357. Onani zenizeni.
  88. Leu-Semenescu, S., Arnulf, I., Decaix, C., Moussa, F., Clot, F., Boniol, C., Touitou, Y., Levy, R., Vidailhet, M., ndi Roze, E. Kugona ndi zotsatira zoyipa za kutayika kwa serotonin. Kugona 3-1-2010; 33: 307-314. Onani zenizeni.
  89. Omasulidwa RR. Chithandizo cha kutentha kwa msambo ndi 5-hydroxytryptophan. Maturitas 2010; 65: 383-5. Onani zenizeni.
  90. Masabata, B. S. Kapangidwe kazakudya zopatsa thanzi komanso zopangira mankhwala azitsitsimutso komanso zochita za nkhawa: Relarian. Med Sci Monit. 2009; 15: RA256-RA262. Onani zenizeni.
  91. Rondanelli M, Klersy C, Iadarola P, ndi al. Satiety ndi amino-acid mbiri mwa amayi onenepa kwambiri atalandira chithandizo chatsopano pogwiritsa ntchito chomera chachilengedwe. Int J Obes (Chikondi) 2009; 33: 1174-1182. Onani zenizeni.
  92. Maissen CP, Ludin HP. [Kuyerekeza zotsatira za 5-hydroxytryptophan ndi propranolol pakadutsa chithandizo cha migraine]. Schweiz Med Wochenschr 1991; 121: 1585-90 (Pamasamba) Onani zenizeni.
  93. Nkhono W, Bullias D, Charuvastra E, et al. Kuyesedwa kosasinthika, kolamulidwa ndi placebo kwamakonzedwe amino acid munthawi yake komanso kugona mokwanira. Ndine J Ther. 2010; 17: 133-9. Onani zenizeni.
  94. Trujillo-Martin, M. M., Serrano-Aguilar, P., Monton-Alvarez, F., ndi Carrillo-Fumero, R. Kugwiritsa ntchito bwino komanso chitetezo cha chithandizo chamankhwala osokoneza bongo ataxias: kuwunika mwatsatanetsatane. Kusokonezeka Kwa Magalimoto. 6-15-2009; 24: 1111-1124. Onani zenizeni.
  95. Rothman, R. B. Chithandizo cha kunenepa kwambiri ndi "kuphatikiza" mankhwala osokoneza bongo. Ndine J Ther 2010; 17: 596-603. Onani zenizeni.
  96. Chae, HS, Kang, OH, Choi, JG, Oh, YC, Lee, YS, Jang, HJ, Kim, JH, Park, H., Jung, KY, Sohn, DH, ndi Kwon, DY 5-hydroxytryptophan amachita pa njira yotulutsa protein kinase extracellular-signal yokhazikitsidwa ndi protein kinase njira yosinthira cyclooxygenase-2 ndi inducible nitric oxide synthase expression mu RAW 264.7 maselo. Biol Pharm Bull 2009; 32: 553-557. (Adasankhidwa) Onani zenizeni.
  97. Hendricks, E. J., Rothman, R. B., ndi Greenway, F. L. Momwe akatswiri a kunenepa kwambiri amagwiritsira ntchito mankhwala kuti athetse kunenepa kwambiri. Kunenepa kwambiri. (Silver.Spring) 2009; 17: 1730-1735. Onani zenizeni.
  98. Longo, N. Kusokonezeka kwa biopterin metabolism. J Cholowa. Metab Dis 2009; 32: 333-342. Onani zenizeni.
  99. Pons, R. Matenda a phenotypic a matenda a ana a neurotransmitter ndi khanda parkinsonism. J Cholowa. Metab Dis 2009; 32: 321-332. Onani zenizeni.
  100. Schaefer, M., Winterer, J., Sarkar, R., Uebelhack, R., Franke, L., Heinz, A., ndi Friebe, A. Milandu itatu ya tryptophan yowonjezera kapena monotherapy ya hepatitis C ndi IFNalpha -kuyanjana kwamalingaliro. Psychosomatics 2008; 49: 442-446. Onani zenizeni.
  101. Jacobsen, JP, Nielsen, EO, Hummel, R., Redrobe, JP, Mirza, N., ndi Weikop, P. Insensitivity ya mbewa za NMRI posankha serotonin reuptake inhibitors pamayeso oyimitsa mchira atha kusinthidwa ndi mgwirizano ndi 5 -hydroxytryptophan. Psychopharmacology (Berl) 2008; 199: 137-150. Onani zenizeni.
  102. Liu, K. M., Liu, T., Lee, N. C., Cheng, L.Y., Hsiao, K. J., ndi Niu, D. M. Kutsata kwanthawi yayitali kwa odwala aku China aku China amachiritsidwa koyambirira kwa kusowa kwa 6-pyruvoyl-tetrahydropterin synthase. Arch Neurol. 2008; 65: 387-392. Onani zenizeni.
  103. Horvath, GA, Stockler-Ipsiroglu, SG, Salvarinova-Zivkovic, R., Lillquist, YP, Connolly, M., Hyland, K., Blau, N., Rupar, T., ndi Madzi, PJ Autosomal yowerengera GTP cyclohydrolase I kusowa kopanda hyperphenylalaninemia: umboni wa phenotypic wopitilira pakati pa mitundu yayikulu komanso yochulukirapo. Mol.Genet.Metab 2008; 94: 127-131. Onani zenizeni.
  104. Morrow, J. D., Vikraman, S., Imeri, L., ndi Opp, M. R. Zotsatira zakugwiritsa ntchito serotonergic ndi 5-hydroxytryptophan pogona ndi kutentha kwa thupi kwa C57BL / 6J ndi mbewa zosowa za interleukin-6 ndizomwe zimakhudzana ndi nthawi komanso nthawi. Kugona 1-1-2008; 31: 21-33. Onani zenizeni.
  105. (Adasankhidwa) Meolie, AL, Rosen, C., Kristo, D., Kohrman, M., Gooneratne, N., Aguillard, RN, Fayle, R., Troell, R., Townsend, D., Claman, D., Hoban, T., ndi Mahowald, M. Mankhwala osalembetsedwa pakamwa osagona: kuwunika kwa zinthu zopanda umboni. J Clin Kugona Med 4-15-2005; 1: 173-187. Onani zenizeni.
  106. Cangiano C, Ceci F, Cairella M, et al. (Adasankhidwa) Zotsatira za 5-hydroxytryptophan pakudya ndi kutsatira malangizo azakudya mu maphunziro akuluakulu okalamba. Adv Exp Med Biol. 1991; 294: 591-3. (Adasankhidwa) Onani zenizeni.
  107. Petre-Quadens, O. ndi De Lee, C. 5-Hydroxytryptophan ndipo amagona mu Down's syndrome. J Neurol Sci. 1975; 26: 443-453 (Pamasamba) Onani zenizeni.
  108. Lesch, K. P., Hoh, A., Disselkamp-Tietze, J., Wiesmann, M., Osterheider, M., ndi Schulte, H. M. 5-Hydroxytryptamine1A kulandila kwa anthu omwe ali ndi vuto lodziletsa. Kuyerekeza odwala ndi zowongolera. Arch Gen Psychiatry 1991; 48: 540-547 (Pamasamba) Onani zenizeni.
  109. Halladay, AK, Wagner, GC, Sekowski, A., Rothman, RB, Baumann, MH, ndi Fisher, H. Kusintha kwa zakumwa zoledzeretsa, kugonja, komanso kufalitsa kwa monoamine mu makoswe omwe amathandizidwa ndi fentamini ndi 5-hydroxy-L-tryptophan . Kusinthasintha 2006; 59: 277-289. Onani zenizeni.
  110. Curcio, J. J., Kim, L. S., Wollner, D., ndi Pockaj, B. A. Kuthekera kwa 5-hydryoxytryptophan pakuchepetsa kutentha: kuyerekezera. Njira Zina za Med 2005; 10: 216-221. Onani zenizeni.
  111. Victor, S. ndi Ryan, S. W. Mankhwala osokoneza bongo popewa kupweteka kwa mutu kwa ana. Dongosolo Losungidwa la Cochrane. Syst. Rev 2003; CD002761. Onani zenizeni.
  112. George DT, Lindquist T, Rawlings RR, ndi al. Pharmacologic yokonza kudziletsa kwa odwala omwe ali chidakwa: palibe mphamvu ya 5-hydroxytryptophan kapena levodopa. Clin Pharmacol Ther 1992; 52: 553-60 (Pamasamba) Onani zenizeni.
  113. Shaw, K., Turner, J., ndi Del Mar, C. Tryptophan ndi 5-hydroxytryptophan kukhumudwa. Database la Cochrane. Syst Rev 2002; CD003198. Onani zenizeni.
  114. Ciaranello, R. D., Anders, T. F., Barchas, J. D., Berger, P. A., ndi Cann, H. M. Kugwiritsa ntchito 5-hydroxytryptophan mwa mwana yemwe ali ndi matenda a Lesch-Nyhan. Psychiatry Ya Ana Hum Dev 1976; 7: 127-133. Onani zenizeni.
  115. Anderson, L.T, Herrmann, L., ndi Dancis, J. Zotsatira za L-5-hydroxytryptophan pakudziyesa-mutilatin mu matenda a Lesch-Nyhan: lipoti loipa. Neuropadiatrie. 1976; 7: 439-442. Onani zenizeni.
  116. Growdon, J. H., Young, R. R., ndi Shahani, B. T. L-5-hydroxytryptophan pochiza ma syndromes angapo momwe myoclonus amadziwika. Neurology 1976; 26: 1135-1140 (Pamasamba) Onani zenizeni.
  117. Takahashi S, Kondo H, Kato N.Zotsatira za l-5-hydroxytryptophan pa ubongo monoamine metabolism ndi kuwunika momwe amathandizira odwala omwe ali ndi nkhawa. J Psychiatr Res. 1975; 12: 177-87 (Pamasamba) Onani zenizeni.
  118. Preshaw RM, Leavitt D, Hoag G. Zakudya zowonjezera 5-hydroxytryptophan ndi kwamikodzo 5-hydroxyindole acetic acid. CMAJ 2008; 178: 993. Onani zenizeni.
  119. Wolemba Byerley WF, Judd LL, Reimherr FW, Grosser BI. 5-Hydroxytryptophan: kuwunikanso mphamvu yake yothanirana ndi nkhawa komanso zovuta zake. J Clin Psychopharmacol 1987; 7: 127-37 .. Onani zenizeni.
  120. Shaw K, Turner J, Del Mar C. Tryptophan ndi 5-hydroxytryptophan kukhumudwa. Cochrane Database Syst Rev 2002; CD003198. (Adasankhidwa) Onani zenizeni.
  121. Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V. Kafukufuku wosawona wa 5-hydroxytryptophan motsutsana ndi placebo pochiza matenda oyamba a fibromyalgia. J Int Med Res 1990; 18: 201-9. Onani zenizeni.
  122. Johnson KL, Klarskov K, Benson LM, ndi al. Kukhalapo kwa pachimake X ndi zinthu zina zokhudzana ndi izi: zomwe zanenedwa ngati zowopsa ngati 5-hydroxy-L-tryptophan yokhudzana ndi eosinophilia-myalgia syndrome. J Rheumatol. 1999; 26: 2714-7. (Adasankhidwa) Onani zenizeni.
  123. Singhal AB, Caviness VS, Begleiter AF, ndi al. Cerebral vasoconstriction ndi sitiroko mutatha kugwiritsa ntchito mankhwala osokoneza bongo a serotonergic. Neurology 2002; 58: 130-3. (Adasankhidwa) Onani zenizeni.
  124. U. S. Food and Drug Administration, Center for Food Safety ndi Applied Nutrition, Office of Nutritional Products, Labeling, ndi Zakudya Zowonjezera Zakudya. Pepala Lolemba pa L-Tryptophan ndi 5-hydroxy-L-tryptophan, February 2001.
  125. Nardini M, De Stefano R, Iannuccelli M, ndi al. Kuchiza kwa kukhumudwa ndi L-5-hydroxytryptophan kuphatikiza chlorimipramine, kafukufuku wakhungu kawiri. Int J Clin Pharmacol Res. 1983; 3: 239-50. Onani zenizeni.
  126. Ribeiro CA. L-5-Hydroxytryptophan mu prophylaxis yamutu wopanikizika wopweteka: kafukufuku wopangidwa ndi khungu wakhungu kawiri, wosasinthika. Kumutu 2000; 40: 451-6. Onani zenizeni.
  127. Poldinger W, Calanchini B, Schwarz W. Njira yogwiritsira ntchito kukhumudwa: kuchepa kwa serotonin ngati vuto pakulimbana ndi 5-hydroxytryptophan ndi fluvoxamine. Psychopathology 1991; 24: 53-81. Onani zenizeni.
  128. Sternberg EM, Van Woert MH, Achinyamata SN, et al. Kukula kwa matenda ngati scleroderma panthawi yamankhwala a L-5-hydroxytryptophan ndi carbidopa. N Engl J Med 1980; 303: 782-7. Onani zenizeni.
  129. Ulamuliro wa Zakudya ndi Mankhwala ku U.S. Zosalala zimatsimikiziridwa pazakudya zowonjezera 5-hydroxy-L-tryptophan. Pepala Loyankhula la FDA, Ogasiti 31, 1998; T98-48.
  130. Meyer JS, Welch KM, Deshmukh VD, ndi al. Woyambitsa ma Neurotransmitter amino acid pochiza matenda amisala ambiri ndi matenda a Alzheimer's. J Amer Geriat Soc 1977; 25: 289-98 (Pamasamba) Onani zenizeni.
  131. Trouillas P, Brudon F, Adeleine P. Kupititsa patsogolo kwa cerebellar ataxia yokhala ndi levorotatory form 5-hydroxytryptophan: kafukufuku wakhungu kawiri wokhala ndi chidziwitso chazambiri. Mzere Neurol 1988; 45: 1217-22. Onani zenizeni.
  132. Kahn RS, Westenberg HG. L-5-hydroxytryptophan pochiza matenda amisala. J Zimakhudza Kusokonezeka 1985; 8: 197-200. Onani zenizeni.
  133. Cangiano C, Ceci F, Cancino A, et al. (Adasankhidwa) Kudya kakhalidwe ndi kutsatira malangizo azakudya muzolemera za akulu akulu omwe amathandizidwa ndi 5-hydroxytryptophan. Am J Zakudya Zamankhwala 1992; 56: 863-7. Onani zenizeni.
  134. Sarzi Puttini P, Caruso I. Matenda a fibromyalgia oyambira ndi 5-hydroxy-L-tryptophan: kafukufuku wamasiku 90 otseguka. J Int Med Res 1992; 20: 182-9. Onani zenizeni.
  135. Nakajima T, Kudo Y, Kaneko Z.Kuyeza kwa 5-hydroxy-L-tryptophan ngati mankhwala opatsirana. Folia Psychiatr Neurol Jpn 1978; 32: 223-30. Onani zenizeni.
  136. Michelson D, Tsamba SW, Casey R, et al. Matenda okhudzana ndi eosinophilia-myalgia omwe amakhudzana ndi kuwonekera kwa L-5-hydroxytryptophan. J Rheumatol. 1994; 21: 2261-5 (Pamasamba) Onani zenizeni.
  137. Mbalame TC. 5-Hydroxytryptophan: Wopanga Serotonin Precursor Wothandizira. Kuphatikiza Med Rev 1998; 3: 271-80. Onani zenizeni.
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