Kodi prolactinoma ndi chiyani, zizindikiro ndi momwe mankhwala amathandizira
Zamkati
Prolactinoma ndi chotupa chosaopsa chomwe chimapezeka mu pituitary gland, makamaka pamatenda a pituitary omwe amatsogolera kukulitsa kwa prolactin, yomwe ndi hormone yomwe imalimbikitsa ma gland a mammary kuti atulutse mkaka nthawi yapakati komanso yoyamwitsa. Kuchuluka kwa kuchuluka kwa prolactin kumadziwika ndi hyperprolactinemia, yomwe imatha kubweretsa kuwonekera kwa zizindikilo zina monga kusamba mosasamba, kusamba, kusabereka komanso kusowa mphamvu kwa amuna.
Prolactinoma imatha kugawidwa m'magulu awiri kutengera kukula kwake:
- Microprolactinoma, yomwe ili ndi m'mimba mwake osachepera 10 mm;
- Macroprolactinoma, Ili ndi m'mimba mwake wofanana kapena woposa 10 mm.
Kuzindikira kwa prolactinoma kumapangidwa kudzera muyeso ya prolactin m'magazi komanso zotsatira zoyesa kuyerekezera monga maginito resonance ndi computed tomography. Chithandizo chikuyenera kulimbikitsidwa ndi endocrinologist kapena neurologist malingana ndi mawonekedwe a chotupacho, ndipo kugwiritsa ntchito mankhwala osokoneza bongo kuti athetse milingo ya prolactin ndikuchepetsa zizindikilo zikuwonetsedwa.
Zizindikiro za Prolactinoma
Zizindikiro za Prolactinoma ndizokhudzana ndi kuwonjezeka kwa kuchuluka kwa ma prolactin, ndipo pakhoza kukhala:
- Kutulutsa mkaka wa m'mawere ngakhale osakhala ndi pakati kapena kuti wabereka mwana posachedwa;
- Msambo wosasamba kapena kusamba kulikonse,
- Kusabereka;
- Mphamvu, kwa amuna;
- Kuchepetsa chilakolako chogonana;
- Kukula kwa m'mawere mwa amuna.
Ngakhale kuchuluka kwa prolactin kumakhudzana ndi prolactinoma, zitha kuchitika chifukwa cha zochitika zina monga polycystic ovary syndrome, hypothyroidism, kupsinjika, panthawi yapakati komanso kuyamwitsa, kulephera kwa impso, kulephera kwa chiwindi kapena chifukwa cha mankhwala ena. Dziwani zambiri pazomwe zimayambitsa hyperprolactinemia.
Momwe matendawa amapangidwira
Matenda a prolactinoma amayamba poyang'ana kuchuluka kwa kufalikira kwa prolactin ndipo zikhalidwezo zimatha kusiyanasiyana kutengera mtundu wa prolactinoma:
- Pankhani ya microprolactinoma, mitengo ya prolactin ili pakati pa 50 ndi 300 ng / dL;
- Pankhani ya macroprolactinoma, ma practactin ali pakati pa 200 ndi 5000 ng / dL.
Kuphatikiza pa kuchuluka kwa kufalikira kwa prolactin, adokotala nthawi zambiri amawonetsa magwiridwe antchito a comput tomography ndi maginito amawu ojambula kuti atsimikizire mawonekedwe a chotupacho. Densitometry ya mafupa ndi echocardiogram itha kupemphedwanso kuti muwone ngati pali zovuta zina zokhudzana ndi kuchuluka kwa kuchuluka kwa kufalitsa kwa prolactin.
Onani momwe mayeso a prolactin amachitikira ndi momwe mungamvetsetse zotsatira zake.
Chithandizo cha prolactinoma
Chithandizo cha prolactinoma cholinga chake ndikuchepetsa zizindikiritso ndikubwezeretsanso chonde, kuphatikiza pakuwongolera kuchuluka kwa ma prolactin ndikuwongolera kukula kwa chotupa. Chithandizo choyamba chomwe wowonetsa endocrinologist ali nacho ndi mankhwala monga Bromocriptine ndi Cabergoline.
Ngati milingo ya prolactin siyimayendetsedwa, adokotala amalimbikitsa opaleshoni kuti ichotse chotupacho. Kuphatikiza apo, ngati munthuyo samvera mankhwala ndi mankhwala, radiotherapy ingalimbikitsidwe kuti muchepetse kukula kwa chotupacho komanso kupewa kupitilira kwa matendawa.