Momwe Zithandizo Zochedwetsera Kutha Ntchito Zimatha

Zamkati

• Ndi mankhwala ati omwe amagwiritsidwa ntchito kwambiri
• 1. Leuprolide
• 2. Triptorelin
• 3. Mbiri
• Momwe Mankhwala Amagwirira Ntchito
• Zotsatira zoyipa

Mankhwala omwe amachedwa kutha msinkhu ndi zinthu zomwe zimakhudza magwiridwe antchito a pituitary gland, kulepheretsa kutulutsa kwa LH ndi FSH, mahomoni awiri omwe ndiofunika kwambiri pakukula kwa ana.

Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito ngati atha msinkhu msanga, kuchedwetsa ntchitoyi ndikulola kuti mwana azikula mofanana ndi ana azaka zake.

Kuphatikiza apo, mankhwalawa atha kugwiritsidwanso ntchito pa dysphoria ya jenda, momwe mwanayo samasangalalira ndi jenda lomwe adabadwiramo, kumupatsa nthawi yochulukirapo kuti adzifufuze asanapange chisankho chokhwima komanso chotsimikiza monga kusintha kugonana.

Ndi mankhwala ati omwe amagwiritsidwa ntchito kwambiri

Njira zina zomwe zitha kuwonetsedwa kuti zichedwa kutha msinkhu ndi izi:

1. Leuprolide

Leuprolide, yomwe imadziwikanso kuti leuprorelin, ndimadzimadzi opanga omwe amagwira ntchito pochepetsa kutulutsa thupi kwa mahomoni a gonadotropin, kutsekereza kugwira ntchito kwa mazira ndi machende.

Mankhwalawa amaperekedwa ngati jakisoni kamodzi pamwezi, ndipo kuchuluka kwake kumafunikira molingana ndi kulemera kwa mwanayo.

2. Triptorelin

Triptorelin ndi mahomoni opanga, omwe amafanana ndi leuprolide, omwe amayeneranso kuperekedwa mwezi uliwonse.

3. Mbiri

Histrelin imagwiranso ntchito poletsa thupi kupanga mahomoni a gonadotropin, koma imayikidwa ngati chomera chomwe chimayikidwa pansi pa khungu kwa miyezi 12.

Mankhwalawa akaimitsidwa, kupanga mahomoni kumabwereranso mwakale ndipo msinkhu umatha msanga.

Dziwani momwe mungadziwire zisonyezo za kutha msinkhu ndikuwona chomwe chimayambitsa.

Momwe Mankhwala Amagwirira Ntchito

Mwa kulepheretsa mahomoni a gonadotropin ndi thupi, mankhwalawa amalepheretsa chithokomiro kutulutsa mahomoni awiri, omwe amadziwika kuti LH ndi FSH, omwe ali ndi udindo wolimbikitsa machende mwa anyamata kuti apange testosterone ndipo, mwa atsikana, thumba losunga mazira kutulutsa ma estrogens:

• Testosterone: ndi mahomoni akulu ogonana amuna, omwe amapangidwa kuyambira pafupifupi zaka 11, ndipo omwe ali ndi gawo loyambitsa kukula kwa tsitsi, kukula kwa mbolo ndikusintha kwa mawu;
• Estrogen: imadziwika kuti mahomoni achikazi omwe amayamba kupangidwa mozungulira zaka za 10, kuti athandize kukula kwa mabere, kugawira mafuta, kupanga mawonekedwe achikazi kwambiri, ndikuyamba kusamba.

Chifukwa chake, pochepetsa kuchuluka kwamahomoni ogonana mthupi, mankhwalawa amatha kuchedwetsa zosintha zonse zakutha msinkhu, kuteteza izi kuti zisachitike.

Zotsatira zoyipa

Chifukwa zimakhudza kapangidwe ka mahomoni, mankhwala amtunduwu amatha kukhala ndi zovuta zina mthupi monga kupangitsa kusintha kwadzidzidzi kwamalingaliro, kupweteka kwa mafupa, kupuma movutikira, chizungulire, kupweteka mutu, kufooka komanso kupweteka wamba.