Choloŵa cha fructose tsankho

Holeitary fructose intolerance ndi vuto lomwe limapangitsa munthu kusowa puloteni yofunikira kuti awononge fructose. Fructose ndi shuga wazipatso yemwe mwachilengedwe amapezeka mthupi. Fructose yopangidwa ndi anthu imagwiritsidwa ntchito ngati chotsekemera mu zakudya zambiri, kuphatikiza chakudya cha ana ndi zakumwa.

Izi zimachitika thupi likasowa enzyme yotchedwa aldolase B. Izi zimafunikira kuti athane ndi fructose.

Ngati munthu wopanda mankhwalawa adya fructose kapena sucrose (nzimbe kapena shuga wa beet, shuga wa patebulo), kusintha kwamavuto amthupi kumachitika mthupi. Thupi silingathe kusintha mtundu womwe umasunga shuga (glycogen) kukhala shuga. Zotsatira zake, shuga wamagazi amagwa ndipo zinthu zowopsa zimakunda m'chiwindi.

Kusalolera kwa fructose ndikobadwa nako, zomwe zikutanthauza kuti zitha kupitilizidwa kudzera m'mabanja. Ngati makolo onse atenga mtundu wa aldolase B wosagwira ntchito, mwana aliyense ali ndi mwayi wakukhudzidwa ndi 25% (1 mu 4).

Zizindikiro zimawoneka mwana atayamba kudya chakudya kapena chilinganizo.

Zizindikiro zoyambirira za kusagwirizana kwa fructose ndizofanana ndi za galactosemia (kulephera kugwiritsa ntchito shuga galactose). Zizindikiro zamtsogolo zimakhudzana kwambiri ndi matenda a chiwindi.

Zizindikiro zimaphatikizapo:

• Kugwedezeka
• Kugona mokwanira
• Kukwiya
• Khungu lachikaso kapena loyera la maso (jaundice)
• Kudyetsa bwino ndikukula ngati khanda, kulephera kukula bwino
• Mavuto mukatha kudya zipatso ndi zakudya zina zomwe zimakhala ndi fructose kapena sucrose
• Kusanza

Kuyesedwa kwakuthupi kumatha kuwonetsa:

• Kukulitsa chiwindi ndi ndulu
• Jaundice

Mayesero omwe amatsimikizira kuti matendawa ndi awa:

• Mayeso okutira magazi
• Mayeso a shuga wamagazi
• Maphunziro a enzyme
• Kuyesedwa kwachibadwa
• Ntchito ya impso
• Kuyesa kwa chiwindi
• Chiwindi
• Uric acid kuyesa magazi
• Kupenda kwamadzi

Shuga wamagazi amakhala wotsika, makamaka atalandira fructose kapena sucrose. Magulu a asidi a Uric adzakhala okwera.

Kuchotsa fructose ndi sucrose kuchokera ku zakudya ndizothandiza kwa anthu ambiri. Zovuta zitha kuthandizidwa. Mwachitsanzo, anthu ena amatha kumwa mankhwala kuti achepetse uric acid m'magazi awo ndikuchepetsa chiopsezo cha gout.

Kusalolera kwa fructose kungakhale kofatsa kapena koopsa.

Kupewa fructose ndi sucrose kumathandiza ana ambiri omwe ali ndi vutoli. Matendawa amakhala abwino nthawi zambiri.

Ana ochepa omwe ali ndi matendawa amatha kudwala matenda owopsa a chiwindi. Ngakhale kuchotsa fructose ndi sucrose kuchokera ku zakudya sizingateteze matenda owopsa a chiwindi mwa ana awa.

Momwe munthu amachitira bwino zimadalira:

• Posakhalitsa matendawa amapezeka
• Kodi fructose ndi sucrose zingachotsedwe posachedwa bwanji pachakudya
• Momwe ma enzyme amagwirira ntchito mthupi

Zovuta izi zitha kuchitika:

• Kupewa zakudya zomwe zili ndi fructose chifukwa cha zovuta zake
• Magazi
• Gout
• Matenda chifukwa chodya zakudya zokhala ndi fructose kapena sucrose
• Kulephera kwa chiwindi
• Shuga wamagazi ochepa (hypoglycemia)
• Kugwidwa
• Imfa

Itanani yemwe akukuthandizani ngati mwana wanu wayamba kukhala ndi matendawa atayamba kudyetsa. Ngati mwana wanu ali ndi vutoli, akatswiri amalangiza kuti akaonane ndi dokotala wodziwa zamankhwala amthupi kapena kagayidwe kazinthu.

Mabanja omwe ali ndi mbiri yakubadwa kwa tsankho la fructose omwe akufuna kukhala ndi mwana atha kulingalira za upangiri wa majini.

Zowononga zambiri za matendawa zitha kupewedwa ndi kuchepa kwa kudya kwa fructose ndi sucrose.

Fructosemia; Tsankho Fructose; Fructose aldolase B-kusowa; Kuperewera kwa Fructose-1, 6-bisphosphate aldolase

Bonnardeaux A, Bichet DG. Matenda obadwa nawo a aimpso tubule. Mu: Skorecki K, Chertow GM, Marsden PA, Taal MW, Yu ASL, olemba. Brenner ndi Rector a Impso. 10th ed. Philadelphia, PA: Elsevier; 2016: chap 45.

Kishnani PS, Chen YT. Zofooka mu kagayidwe chakudya. Mu: Kliegman RM, St. Geme JW, Schor NF, Blum NJ, Shah SS, Tasker RC, Wilson KM, olemba. Nelson Textbook of Pediatrics. Wolemba 21. Philadelphia, PA: Elsevier; 2020: chap 105.

Nadkarni P, Weinstock RS. Zakudya. Mu: McPherson RA, Pincus MR, olemba., Eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Wachitatu. St Louis, MO: Elsevier; 2017: mutu 16.

Scheinman SJ. Matenda opatsirana poyambitsa impso. Mu: Gilbert SJ, Weiner DE, olemba., Eds. Primer pa Matenda a Impso a National Kidney Foundation. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 38.