Thrombocytopenia yomwe imayambitsa mankhwala osokoneza bongo

Thrombocytopenia ndi vuto lililonse lomwe mulibe ma platelet okwanira. Ma Platelet ndi maselo m'magazi omwe amathandiza magazi kuundana. Kuchuluka kwamaplateletti kumapangitsa magazi kutuluka kwambiri.

Mankhwala kapena mankhwalawa akamayambitsa kuchuluka kwamagulu ochepa, amatchedwa thrombocytopenia wothandizidwa ndi mankhwala.

Mankhwala opatsirana pogwiritsa ntchito mankhwala osokoneza bongo a thrombocytopenia amapezeka pamene mankhwala ena amawononga maselo othandiza magazi kuundana kapena kusokoneza thupi kuti likhale lokwanira.

Pali mitundu iwiri ya mankhwala osokoneza bongo omwe amachititsa kuti thrombocytopenia: chitetezo cha mthupi komanso chosagwira ntchito.

Ngati mankhwala amachititsa kuti thupi lanu lipange ma antibodies, omwe amafufuza ndikuwononga magazi anu othandiza magazi kuundana, vutoli limatchedwa immune thrombocytopenia. Heparin, wochepetsetsa magazi, ndiye chifukwa chodziwika kwambiri chamankhwala osokoneza bongo a thrombocytopenia.

Ngati mankhwala amalepheretsa mafupa anu kupanga ma platelet okwanira, vutoli limatchedwa non-immune thrombocytopenia. Mankhwala a chemotherapy komanso mankhwala olanda omwe amatchedwa valproic acid atha kubweretsa vutoli.

Mankhwala ena omwe amayambitsa thrombocytopenia omwe amapangidwa ndi mankhwala ndi awa:

• Furosemide
• Golide, yemwe amachiza nyamakazi
• Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)
• Penicillin
• Quinidine
• Quinine
• Ranitidine
• Sulfonamides
• Linezolid ndi maantibayotiki ena
• Zolemba

Kuchepetsa ma platelet kungayambitse:

• Kutuluka magazi mosazolowereka
• Kukhetsa magazi mukamatsuka mano
• Kuvulaza kosavuta
• Onetsani mawanga ofiira pakhungu (petechiae)

Gawo loyamba ndikusiya kugwiritsa ntchito mankhwala omwe akuyambitsa vutoli.

Kwa anthu omwe ali ndi magazi owopsa moyo, chithandizo chitha kukhala:

• Immunoglobulin therapy (IVIG) yoperekedwa kudzera mumitsempha
• Kusinthana kwa plasma (plasmapheresis)
• Kuika magazi m'matangadza
• Mankhwala a Corticosteroid

Kutaya magazi kumatha kuopseza moyo ukachitika muubongo kapena ziwalo zina.

Mayi woyembekezera yemwe ali ndi ma antibodies m'maplateleti amatha kupatsira mwanayo m'mimba.

Itanani yemwe akukuthandizani ngati muli ndi magazi osadziwika kapena kuvulala ndipo mukumwa mankhwala, monga omwe atchulidwa pamwambapa.

Thrombocytopenia yotulutsa mankhwala; Immune thrombocytopenia - mankhwala

• Mapangidwe a magazi
• Kuundana kwamagazi

Abrams CS. Thrombocytopenia. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. Wolemba 25. Philadelphia, PA: Elsevier Saunders; 2016: chap 172.

Zolemba pa Warkentin TE. Thrombocytopenia yoyambitsidwa ndi kuwonongedwa kwa ma platelet, hypersplenism, kapena hemodilution. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 132.