Matenda osokoneza bongo

Neurosyphilis ndimatenda amtundu waubongo kapena msana. Nthawi zambiri amapezeka mwa anthu omwe akhala ali ndi chindoko osachiritsidwa kwazaka zambiri.

Neurosyphilis imayambitsidwa ndi Treponema pallidum. Awa ndi mabakiteriya omwe amayambitsa chindoko. Neurosyphilis nthawi zambiri imachitika pafupifupi zaka 10 mpaka 20 munthu atayamba kudwala chindoko. Sikuti aliyense amene ali ndi syphilis amakhala ndi vutoli.

Pali mitundu inayi yosiyanasiyana ya neurosyphilis:

• Asymptomatic (mawonekedwe wamba)
• General paresis
• Kusuntha
• Masamba dorsalis

Asymptomatic neurosyphilis imachitika asanafike chizindikiro chindoko. Kutanthauza kuti palibe zisonyezo.

Zizindikiro nthawi zambiri zimakhudza dongosolo lamanjenje. Kutengera mtundu wa neurosyphilis, zizindikilo zimatha kuphatikizira izi:

• Kuyenda modabwitsa (gait), kapena kulephera kuyenda
• Dzanzi zala zakumapazi, mapazi, kapena miyendo
• Mavuto ndi malingaliro, monga kusokonezeka kapena kusasamala bwino
• Mavuto amisala, monga kukhumudwa kapena kukwiya
• Mutu, khunyu, kapena khosi lolimba
• Kutaya chikhodzodzo (kusadziletsa)
• Kugwedezeka, kapena kufooka
• Mavuto owoneka, ngakhale khungu

Wothandizira zaumoyo wanu angawunike bwino ndipo atha kupeza izi:

• Maganizo osazolowereka
• Kutsekeka kwa minofu
• Kupanikizika kwa minofu
• Kusintha kwa malingaliro

Kuyezetsa magazi kumatha kuchitika kuti muzindikire zinthu zomwe mabakiteriya amayambitsa syphilis, izi zikuphatikiza:

• Treponema pallidum tinthu agglutination assay (TPPA)
• Mayeso a kafukufuku wa matenda a Venereal (VDRL)
• Kutentha kwa fluorescent treponemal antibody (FTA-ABS)
• Reagin wofulumira (RPR)

Ndi neurosyphilis, ndikofunikira kuyesa msana wam'mimba kuti muwone ngati pali chindoko.

Kuyesa kofufuza zovuta zamanjenje kungaphatikizepo:

• Cerebral angiogram
• Mutu wa CT
• Lumbar puncture (tap tap) ndi kusanthula kwa cerebrospinal fluid (CSF)
• Kujambula kwa MRI kwa ubongo, ubongo, kapena msana

Mankhwala a penicillin amagwiritsidwa ntchito pochiza matenda amitsempha. Itha kuperekedwa m'njira zosiyanasiyana:

• Jekeseni wamitsempha kangapo patsiku kwa masiku 10 mpaka 14.
• Pakamwa kanayi patsiku, kuphatikiza jakisoni wa minofu ya tsiku ndi tsiku, onse omwe amatengedwa kwa masiku 10 kapena 14.

Muyenera kuyezetsa magazi ndikutsata miyezi 3, 6, 12, 24, ndi 36 kuti muwone ngati matenda atha. Mudzafunika ma lumbar otsatira a CSF pakatha miyezi isanu ndi umodzi. Ngati muli ndi HIV / AIDS kapena matenda ena, nthawi yanu yotsatira ingakhale yosiyana.

Neurosyphilis ndi vuto lowopsa la syphilis. Momwe mumakhalira bwino zimadalira momwe matenda amthupi amathandizira munthu asanalandire chithandizo. Cholinga cha chithandizo ndikuteteza kuwonongeka kwina. Zambiri mwa zosinthazi sizisinthidwa.

Zizindikiro zimatha kukulira pang'onopang'ono.

Itanani omwe akukuthandizani ngati mudakhalapo ndi syphilis m'mbuyomu ndipo tsopano muli ndi zizindikilo zamavuto amanjenje.

Kuzindikira mwachangu ndi kuchiza matenda oyamba a syphilis kumatha kuteteza neurosyphilis.

Chindoko - neurosyphilis

• Central dongosolo lamanjenje ndi zotumphukira zamanjenje
• Chindoko chakumapeto

Zowonjezera Kutsekedwa kwa msana ndi kuyezetsa madzi amadzimadzi. Mu: Roberts JR, Custalow CB, Thomsen TW, olemba., Eds. Ndondomeko Zachipatala za Roberts ndi Hedges mu Emergency Medicine ndi Acute Care. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2019: chap 60.

National Institute of Neurological Disorders ndi tsamba la Stroke. Matenda osokoneza bongo. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Idasinthidwa pa Marichi 27, 2019. Idapezeka pa February 19, 2021.

Radolf JD, Tramont EC, Salazar JC. Chindoko (Treponema pallidum). Mu: Bennett JE, Dolin R, Blaser MJ, olemba., Eds. Mandell, Douglas, ndi Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 237.