Cholowa hemorrhagic telangiectasia

Therangiectasia yotengera magazi (HHT) ndi matenda obadwa nawo m'mitsempha yamagazi yomwe imatha kuyambitsa magazi ochulukirapo.

HHT imadutsa m'mabanja momwe amafunikira kwambiri. Izi zikutanthauza kuti jini yosazolowereka imafunika kuchokera kwa kholo limodzi kuti athe kutenga matendawa.

Asayansi apeza majini anayi okhudzidwa ndi izi. Zonsezi zimawoneka ngati zofunika kuti mitsempha ya magazi ikule bwino. Kusintha kwa mtundu uliwonse wa majiniwa kumayambitsa HHT.

Anthu omwe ali ndi HHT amatha kukhala ndi mitsempha yachilendo m'magawo angapo amthupi. Zombozi zimatchedwa kuti arteriovenous malformations (AVMs).

Ngati ali pakhungu, amatchedwa telangiectasias. Malo omwe amapezeka kwambiri ndi milomo, lilime, makutu, ndi zala. Mitsempha yamagazi yachilendo imatha kukhalanso muubongo, mapapo, chiwindi, matumbo, kapena madera ena.

Zizindikiro za matendawa ndi monga:

• Kutulutsa magazi pafupipafupi mwa ana
• Kutulutsa magazi m'matumbo (GI), kuphatikiza kutaya magazi m'mipando, kapena malo amdima kapena akuda
• Kugwidwa kapena kusadziwika, zikwapu zazing'ono (kuchokera kutaya magazi kulowa muubongo)
• Kupuma pang'ono
• Kukulitsa chiwindi
• Mtima kulephera
• Kuchepa kwa magazi chifukwa cha chitsulo chochepa

Wothandizira zaumoyo adzakufufuza ndikufunsa za zizindikiro zanu. Wopatsa chidziwitso amatha kuzindikira ma telangiectases poyesedwa. Nthawi zambiri pamakhala mbiri yabanja yazimenezi.

Mayeso ndi awa:

• Mayeso amwazi wamagazi
• Kuyesa magazi
• Kuyerekeza kuyesa kwa mtima wotchedwa echocardiogram
• Endoscopy, yomwe imagwiritsa ntchito kamera yaying'ono yolumikizidwa ndi chubu chowonda kuti muyang'ane mkati mwa thupi lanu
• MRI kuti ipeze ma AVM muubongo
• Makina a CT kapena ultrasound kuti azindikire ma AVM m'chiwindi

Kuyezetsa magazi kumapezeka kuti kuyang'ane kusintha kwa majini omwe amakhudzana ndi matendawa.

Chithandizo chitha kukhala:

• Opaleshoni yochiza magazi m'malo ena
• Electrocautery (Kutenthetsa minofu ndi magetsi) kapena opareshoni ya laser kuti muzitha kutulutsa magazi m'mphuno pafupipafupi kapena kolemera
• Matenda am'mitsempha (kubaya chinthu kudzera mu chubu chochepa) kuti athetse mitsempha yamagazi muubongo ndi ziwalo zina za thupi

Anthu ena amayankha mankhwala a estrogen, omwe amachepetsa magawo omwe amatuluka magazi. Iron amathanso kuperekedwa ngati pali kutaya magazi kochuluka, komwe kumabweretsa kuchepa kwa magazi. Pewani kumwa mankhwala ochepetsa magazi. Mankhwala ena omwe amakhudza kukula kwa zotengera zamagazi akuwerengedwa ngati njira zamankhwala zamtsogolo.

Anthu ena angafunike kumwa maantibayotiki asanayambe ntchito ya mano kapena opaleshoni. Anthu omwe ali ndi ma AVM am'mapapo ayenera kupewa kusambira pamadzi kuti ateteze matenda osokoneza bongo (ma bend). Funsani omwe akukuthandizani zomwe mungachite kuti musamalire.

Izi zitha kupereka zambiri pa HHT:

• Malo Othandizira Kuteteza ndi Kuteteza Matenda - www.cdc.gov/ncbddd/hht
• Chiritsani HHT - curehht.org
• National Organisation for Rare Disways - rarediseases.org/rare-diseases/hereditary-hemorrhagic-telangiectasia

Anthu omwe ali ndi matendawa amatha kukhala ndi moyo wathanzi, kutengera komwe ma AVM amakhala mthupi.

Zovuta izi zitha kuchitika:

• Mtima kulephera
• Kuthamanga kwa magazi m'mapapu (kuthamanga kwa magazi)
• Kutuluka magazi mkati
• Kupuma pang'ono
• Sitiroko

Itanani omwe akukuthandizani ngati inu kapena mwana wanu mumatuluka magazi nthawi zambiri pamphuno kapena zizindikiro zina za matendawa.

Uphungu wamtunduwu umalimbikitsidwa kwa maanja omwe akufuna kukhala ndi ana komanso omwe ali ndi mbiri ya banja la HHT. Ngati muli ndi vutoli, chithandizo chamankhwala chingateteze mitundu ina ya sitiroko ndi mtima kulephera.

HHT; Matenda a Osler-Weber-Rendu; Matenda a Osler-Weber-Rendu; Matenda a Rendu-Osler-Weber

• Njira yoyendera
• Mitsempha ya ubongo

Brandt LJ, Aroniadis OC. Mavuto am'mimba am'mimba. Mu: Feldman M, Friedman LS, Brandt LJ, olemba. Sleisenger ndi Matenda a Mimba ndi a Fordtran Amatenda a Chiwindi. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 37.

Cappell MS, Lebwohl O. Telangiectasia yotulutsa magazi mu: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson IH, eds. Kuchiza kwa Matenda a Khungu: Njira Zambiri Zakuchiritsira. Wolemba 4. Philadelphia, PA: Elsevier Saunders; 2014: mutu 98.

McDonald J, Pyeritz RE. Cholowa hemorrhagic telangiectasia. Mu: Adam MP, Ardinger HH, Pagon RA, et al, eds. GeneReviews [Intaneti]. Seattle, WA: Yunivesite ya Washington, Seattle; 1993-2019. Idasinthidwa pa February 2, 2017. Idapezeka pa Meyi 6, 2019.