Mayeso a Troponin

Chiyeso cha troponin chimayeza kuchuluka kwa mapuloteni a troponin T kapena troponin I m'magazi. Mapuloteniwa amamasulidwa pomwe minofu ya mtima yawonongeka, monga yomwe imachitika ndimatenda amtima. Kuwonongeka kwakukulu komwe kumakhalapo pamtima, kuchuluka kwa troponin T ndi ine kudzakhala m'magazi.

Muyenera kuyesa magazi.

Palibe njira zapadera zofunika kukonzekera, nthawi zambiri.

Mutha kumva kupweteka pang'ono kapena mbola pamene singano imayikidwa. Muthanso kumva kupwetekedwa pamalowo magazi atatengedwa.

Chifukwa chodziwika kwambiri choyesera izi ndikuwona ngati vuto la mtima lachitika. Wothandizira zaumoyo wanu adzaitanitsa mayesowa ngati mukumva kupweteka pachifuwa komanso zizindikilo zina za matenda amtima. Mayesowa amabwerezedwa kawiri mumaora ena 6 mpaka 24 otsatira.

Wothandizira anu amathanso kuyeserera izi ngati muli ndi angina yomwe ikuipiraipira, koma palibe zizindikilo zina za matenda amtima. (Angina ndikumva kupweteka pachifuwa komwe kumaganiziridwa kuti kumachokera ku gawo lina la mtima wanu osalandira magazi okwanira.)

Mayeso a troponin amathanso kuchitidwa kuti athandizire ndikuwunika zina zomwe zimayambitsa kuvulala kwa mtima.

Kuyesaku kungachitike limodzi ndi mayeso ena amtundu wamtima, monga CPK isoenzymes kapena myoglobin.

Magulu a mtima troponin nthawi zambiri amakhala otsika kwambiri omwe samapezeka ndi mayesero ambiri amwazi.

Kukhala ndi milingo yodziwika bwino ya troponin maola 12 pambuyo poti kupweteka pachifuwa kwayamba kumatanthauza kuti matenda a mtima sangachitike.

Mtengo wabwinobwino ungasiyane pang'ono pakati pa ma laboratories osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyana (mwachitsanzo, "high sensitivity troponin test") kapena kuyesa zitsanzo zosiyanasiyana. Komanso, ma lab ena amakhala ndi ma cut cut osiyanasiyana a "normal" komanso "infarction of myocardial infarction." Lankhulani ndi omwe akukuthandizani za tanthauzo la zotsatira zanu zoyeserera.

Ngakhale kuwonjezeka pang'ono pamlingo wa troponin nthawi zambiri kumatanthauza kuti pakhala kuwonongeka pamtima. Matenda a troponin okwera kwambiri ndi chizindikiro chakuti kudwala kwamtima kwachitika.

Odwala ambiri omwe adadwala matenda a mtima awonjezera ma troponin mkati mwa maola 6. Pambuyo maola 12, pafupifupi aliyense amene wadwala matenda amtima adzakhala atakweza gawo.

Magulu a Troponin amatha kukhalabe okwera kwa milungu iwiri kapena iwiri mutadwala mtima.

Kuchuluka kwa ma troponin atha kukhalanso chifukwa cha:

• Kugunda kwamtima modabwitsa
• Kuthamanga kwa magazi m'mitsempha yamapapo (pulmonary hypertension)
• Kutsekedwa kwamitsempha yam'mapapo ndi magazi, mafuta, kapena chotupa (pulmonary embolus)
• Kulephera kwa mtima
• Mitsempha ya Coronary spasm
• Kutupa kwa minofu yamtima nthawi zambiri chifukwa cha kachilombo (myocarditis)
• Kuchita masewera olimbitsa thupi kwakanthawi (mwachitsanzo, chifukwa cha marathons kapena ma triathlons)
• Zovuta zomwe zimavulaza mtima, monga ngozi yagalimoto
• Kuchepa kwa minofu ya mtima (cardiomyopathy)
• Matenda a impso a nthawi yayitali

Kuchuluka kwa ma troponin amathanso chifukwa cha njira zina zamankhwala monga:

• Angioplasty yamtima / kununkha
• Kutsekemera kwa mtima kapena kusintha kwa mtima wamagetsi (kudodometsa mtima kwa akatswiri azachipatala kuti athetse vuto la mtima)
• Tsegulani opaleshoni yamtima
• Kuchotsa mafunde pafupipafupi pamtima

Zindikirani; TnI; Malangizo TnT; Troponin woyamba wa mtima I; Troponin yodziwika ndi mtima T; cTnl; cTnT

Bohula EA, Morrow DA. ST-Elevation infarction ya myocardial: kasamalidwe. Mu: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2018: mutu 59.

Bonaca, MP, Sabatine MS. Yandikirani kwa wodwalayo ndi kupweteka pachifuwa. Mu: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2019: mutu 56.

Levine GN, Bates ER, Blankenship JC, ndi al. 2015 ACC / AHA / SCAI Yakhazikika pamalingaliro oyambira omwe angachitike kwa odwala omwe ali ndi ST-Elevation myocardial infarction: zosintha za 2011 ACCF / AHA / SCAI yaupangiri wothandizidwa ndi coronary and 2013 ACCF / AHA wowongolera kasamalidwe ka ST- Elevation myocardial infarction: lipoti la American College of Cardiology / American Heart Association Task Force pamayendedwe azachipatala ndi Society for Cardiovascular Angiography and Intervention. Kuzungulira. 2016; 133 (11): 1135-1147. PMID: 26490017 www.ncbi.nlm.nih.gov/pubmed/26490017.

Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD; Executive Group m'malo mwa Joint European Society of Cardiology (ESC) / American College of Cardiology (ACC) / American Heart Association (AHA) / World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Tanthauzo Lachinayi la Universal Myocardial Infarction (2018). Kuzungulira. 2018; 138 (20): e618-e651 PMID: 30571511 www.ncbi.nlm.nih.gov/pubmed/30571511. (Adasankhidwa)