Mlembi: Joan Hall
Tsiku La Chilengedwe: 3 Febuluwale 2021
Sinthani Tsiku: 29 Jayuwale 2025
Anonim
SURPASS ET: ropeginterferon versus anagrelide as second line therapy in essential thrombocythemia
Kanema: SURPASS ET: ropeginterferon versus anagrelide as second line therapy in essential thrombocythemia

Zamkati

Anagrelide amagwiritsidwa ntchito pochepetsa kuchuluka kwa magazi othandiza magazi kuundana (mtundu wa maselo amwazi omwe amafunikira kuti athane ndi magazi) m'magazi a odwala omwe ali ndi vuto la m'mafupa, momwe thupi limapangira mitundu yambiri yamitundu yamagazi, monga thrombocythemia yofunikira (momwe thupi limapangira ma platelet ochulukirapo) kapena polycythemia vera (momwe thupi limapangira maselo ofiira ochulukirapo ndipo nthawi zina ma platelet ambiri). Anagrelide ali mgulu la mankhwala otchedwa ma platelet-reduction agents. Zimagwira ntchito pochepetsa kupangidwa kwa ma platelet mthupi.

Anagrelide amabwera ngati kapisozi kuti atenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kawiri kapena kanayi patsiku. Tengani anagrelide mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani anagrelide ndendende monga mwalamulo. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.


Dokotala wanu mwina angakuyambitseni pa mlingo wochepa wa anagrelide ndipo pang'onopang'ono muwonjezere mlingo wanu, osati kangapo kamodzi pa sabata. Dokotala wanu akhoza kusintha mlingo wanu mukamalandira chithandizo kutengera momwe thupi lanu lingayankhire mankhwala. Tsatirani malangizowa mosamala.

Anagrelide amatha kuthandizira kuwongolera matenda anu koma sangachiritse. Pitilizani kutenga anagrelide ngakhale mukumva bwino. Osasiya kumwa anagrelide osalankhula ndi dokotala. Ngati mwasiya mwadzidzidzi kugwiritsa ntchito anagrelide, kuchuluka kwa ma platelet m'magazi anu kudzawonjezeka ndipo mutha kukhala ndi zizindikilo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanatenge anagrelide,

  • uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la anagrelide kapena mankhwala aliwonse.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: atazanavir (Reyataz); cilostazol (Pletal); cimetidine (Tagamet); clozapine (Clozaril); cyclobenzaprine (Flexeril); maantibayotiki a fluoroquinolone kuphatikiza ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), ena; fluvoxamine (Luvox); imipramine (Tofranil); inamrinone; mexiletine (Mexitil); milrinone (Primacor); naproxen (Aleve, Naprosyn, ku Prevacid NapraPAC); riluzole (Rilutek); sucralfate (Carafate); tacrine (Cognex); theophylline (Elixophyllin, Theo-24, Theolair, ena); ndi ticlopidine (Ticlid). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu ngati mwakhalapo ndi matenda otuluka magazi; kuthamanga kapena kuthamanga kwa magazi; tsankho la lactose (kulephera kugaya mkaka) kapena matenda amtima, impso, kapena chiwindi.
  • Musatenge anagrelide ngati muli ndi pakati kapena mukufuna kukhala ndi pakati.Muyenera kugwiritsa ntchito njira yolerera yoletsa kutenga mimba mukamamwa ndi anagrelide. Lankhulani ndi dokotala wanu za mitundu yoletsa yomwe ili yoyenera kwa inu. Mukakhala ndi pakati mukatenga anagrelide, itanani dokotala wanu mwachangu. Osamayamwitsa mukamamwa anagrelide.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukugwiritsa ntchito anagrelide.
  • Muyenera kudziwa kuti anagrelide imatha kukupangitsani kukhala ozunguzika, makamaka mukayamba kumwa mankhwalawa. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
  • Muyenera kudziwa kuti anagrelide imatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukadzuka msanga kuchokera pamalo abodza. Izi ndizofala kwambiri mukayamba kumwa anagrelide. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.
  • konzekerani kupeŵa kuwunika kwa dzuwa kosafunikira kapena kwanthawi yayitali komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zoteteza ku dzuwa. Anagrelide imatha kupangitsa khungu lanu kuzindikira kuwala kwa dzuwa.

Lankhulani ndi dokotala wanu za kudya mphesa ndi kumwa madzi amphesa mukamamwa mankhwalawa.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Anagrelide amatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • mutu
  • mpweya
  • nseru
  • kusanza
  • kutsegula m'mimba
  • kudzimbidwa
  • kupweteka m'mimba
  • kutentha pa chifuwa
  • kugwedeza
  • kusowa chilakolako
  • mphuno
  • m'mphuno
  • chikhure
  • zilonda mkamwa
  • chizungulire
  • kukhumudwa
  • manjenje
  • kuyiwala
  • chisokonezo
  • kuvuta kugona kapena kugona
  • kusowa mphamvu kapena kugona
  • kufooka
  • kupweteka kwa minofu, olowa kapena kumbuyo
  • kukokana kwamiyendo
  • kutayika tsitsi
  • malungo
  • zizindikiro ngati chimfine
  • pokodza kwambiri
  • kulira m'makutu
  • kuyabwa

Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • zidzolo
  • ming'oma
  • kutuluka mwachilendo kapena kuphwanya
  • magazi mkodzo kapena chopondapo
  • chimbudzi chakuda kapena chochedwa
  • kupweteka pachifuwa
  • kumenyedwa kwamphamvu pachifuwa
  • kugunda kwamphamvu, kwamphamvu, kapena kosasinthasintha
  • kutupa kwa mikono, manja, mapazi, akakolo kapena miyendo yakumunsi
  • kuvuta kupuma
  • chifuwa
  • mawu odekha kapena ovuta
  • kukomoka
  • kufooka kapena kufooka kwa mkono kapena mwendo
  • kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
  • kulanda
  • kusintha kwa masomphenya

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).


Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala kapena kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

  • kutuluka mwachilendo kapena kuphwanya

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu lingayankhire anagrelide.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Agrylin®
Idasinthidwa Komaliza - 08/15/2015

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