Ranitidine jekeseni

Zamkati

• Jakisoni wa Ranitidine amagwiritsidwa ntchito mwa anthu omwe ali mchipatala kuti athetse vuto linalake m'mimba momwe mumatulutsa asidi wambiri kapena kuchiza zilonda (zilonda zamkati mwa m'mimba kapena m'matumbo) zomwe sizinachiritsidwe bwino ndi mankhwala ena. Jakisoni wa Ranitidine amagwiritsidwanso ntchito kwakanthawi kochepa mwa anthu omwe sangathe kumwa mankhwala akumwa
• Asanalandire jakisoni wa ranitidine,
• Ranitidine jekeseni imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

[Wolemba 04/01/2020]

NKHANI: A FDA adalengeza kuti ikupempha opanga kuti achotse mankhwala onse ndi owonjezera (OTC) a ranitidine pamsika nthawi yomweyo.

Ili ndiye gawo laposachedwa pakufufuza komwe kumachitika za mankhwala omwe amadziwika kuti N-Nitrosodimethylamine (NDMA) mu mankhwala a ranitidine (omwe amadziwika kuti Zantac). NDMA ndi khansa yamagazi yamunthu (chinthu chomwe chingayambitse khansa). FDA yatsimikiza kuti kusadetsedwa kwa mankhwala ena a ranitidine kumawonjezeka pakapita nthawi ndipo ikasungidwa pamwambamwamba kuposa kutentha kungapangitse kuti ogula azikhala pazosavomerezeka zodetsazi. Chifukwa cha pempholi lofunsira kuti atulutse msika, zinthu za ranitidine sizipezeka pamankhwala atsopano kapena omwe alipo kale kapena kugwiritsa ntchito OTC ku U.S.

MALANGIZO: Ranitidine ndi blockamine ya histamine-2, yomwe imachepetsa kuchuluka kwa asidi opangidwa ndi m'mimba. Mankhwala a ranitidine amavomerezedwa pazizindikiro zingapo, kuphatikiza chithandizo ndi kupewa zilonda zam'mimba ndi m'matumbo komanso kuchiza matenda a reflux am'mimba.

Malangizo:

• Ogwiritsa: A FDA akulangizanso ogula omwe akutenga OTC ranitidine kuti asiye kumwa mapiritsi kapena madzi aliwonse omwe ali nawo pano, kuwataya moyenera osagula ena; kwa iwo omwe akufuna kupitiliza kuchiza matenda awo, ayenera kulingalira zogwiritsa ntchito zinthu zina zovomerezeka za OTC.
• Odwala: Odwala omwe amamwa mankhwala a ranitidine ayenera kulankhula ndi akatswiri awo azaumoyo za njira zina zamankhwala asanayimitse mankhwalawo, popeza pali mankhwala angapo omwe amavomerezedwa kuti agwiritsidwe ntchito mofananamo ndi ranitidine omwe alibe zoopsa zomwezi kuchokera ku NDMA. Mpaka pano, kuyesa kwa FDA sikunapeze NDMA mu famotidine (Pepcid), cimetidine (Tagamet), esomeprazole (Nexium), lansoprazole (Prevacid) kapena omeprazole (Prilosec).
• Ogulitsa ndi Odwala:Potengera mliri wapano wa COVID-19, a FDA amalimbikitsa odwala ndi ogula kuti asatenge mankhwala awo kumalo obwezera mankhwala koma amatsatira njira zomwe a FDA akuyembekeza, zomwe zimapezeka pa: https://bit.ly/3dOccPG, zomwe zimaphatikizapo njira kutaya bwino mankhwalawa kunyumba.

Kuti mumve zambiri pitani patsamba la FDA ku: http://www.fda.gov/Safety/MedWatch/SafetyInformation ndi http://www.fda.gov/Drugs/DrugSafety.

Jakisoni wa Ranitidine amagwiritsidwa ntchito mwa anthu omwe ali mchipatala kuti athetse vuto linalake m'mimba momwe mumatulutsa asidi wambiri kapena kuchiza zilonda (zilonda zamkati mwa m'mimba kapena m'matumbo) zomwe sizinachiritsidwe bwino ndi mankhwala ena. Jakisoni wa Ranitidine amagwiritsidwanso ntchito kwakanthawi kochepa mwa anthu omwe sangathe kumwa mankhwala akumwa

• kuchiza zilonda,
• kuteteza zilonda kuti zisabwere zitachira,
• kuchiza matenda amtundu wa gastroesophageal reflux (GERD, vuto lomwe kubwerera kumbuyo kwa asidi kuchokera m'mimba kumayambitsa kutentha kwa mtima ndi kuvulala kwa khosi [chubu pakati pakhosi ndi m'mimba]),
• komanso kuthana ndi vuto lomwe m'mimba limatulutsa asidi wambiri, monga Zollinger-Ellison syndrome (zotupa m'mapiko ndi m'matumbo ang'onoang'ono zomwe zidapangitsa kuchuluka kwa asidi m'mimba).

Jakisoni wa Ranitidine ali mgulu la mankhwala otchedwa H₂ zotchinga. Zimagwira ntchito pochepetsa kuchuluka kwa asidi opangidwa m'mimba.

Jakisoni wa Ranitidine amabwera ngati yankho (madzi) osakanikirana ndi madzimadzi ena ndikubayidwa kudzera m'mitsempha (mumtsempha) kwa mphindi 5 mpaka 20. Ranitidine amathanso kubayidwa mu minofu. Nthawi zambiri amaperekedwa maola 6 kapena 8 aliwonse, komanso amathanso kupatsidwa kulowetsedwa nthawi zonse kupitilira maola 24.

Mutha kulandira jakisoni wa ranitidine kuchipatala kapena mutha kupereka mankhwalawo kunyumba. Ngati mukulandira jakisoni wa ranitidine kunyumba, wothandizira zaumoyo wanu akuwonetsani momwe mungagwiritsire ntchito mankhwalawa. Onetsetsani kuti mumvetsetsa izi, ndipo funsani omwe akukuthandizani ngati muli ndi mafunso.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa ranitidine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi matupi awo sagwirizana ndi ranitidine, famotidine, cimetidine, nizatidine (Axid), mankhwala ena aliwonse, kapena china chilichonse mu jakisoni wa ranitidine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: anticoagulants ('magazi ochepetsa magazi') monga warfarin (Coumadin), atazanavir (Reyataz, ku Evotaz), delavirdine (Rescriptor), gefitinib (Iressa), glipizide (Glucotrol), ketoconazole (Nizoral) , midazolam (pakamwa), procainamide, ndi triazolam (Halcion). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mudakhalapo ndi porphyria (matenda obadwa nawo amwazi womwe ungayambitse khungu kapena mavuto amanjenje), kapena matenda a impso kapena chiwindi.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukalandira jakisoni wa ranitidine, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ranitidine jekeseni imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kupweteka, kuwotcha, kapena kuyabwa m'dera lomwe munabayidwa mankhwala

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kugunda kochedwa mtima
• ming'oma
• kuyabwa
• zidzolo
• kuvuta kupuma kapena kumeza
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• kukhumudwa m'mimba
• kutopa kwambiri
• kutuluka mwachilendo kapena kuphwanya
• kusowa mphamvu
• kusowa chilakolako
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• zizindikiro ngati chimfine

Jakisoni wa Ranitidine angayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira jakisoni wa ranitidine.

Musanayezetsedwe kwa labotale, uzani adotolo ndi ogwira nawo ntchito kuti mukugwiritsa ntchito jakisoni wa ranitidine.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zantac^®