Chotsitsa

Zamkati

• Kuti mutenge mapiritsi a deferasirox kuti ayimitsidwe (Exjade), tsatirani izi:
• Musanatenge deferasirox,
• Deferasirox angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena zomwe zatchulidwa mgulu la CHENJEZO LOFUNIKA, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Deferasirox imatha kuwononga impso. Chiwopsezo choti mungawononge impso ndi chachikulu ngati muli ndi matenda ambiri, kapena mukudwala kwambiri chifukwa cha matenda amwazi. Uzani dokotala wanu ngati mwakhalapo ndi matenda a impso. Dokotala wanu angakuuzeni kuti musatenge deferasirox. Ngati mukumane ndi izi, uzani dokotala nthawi yomweyo: kuchepa pokodza, kutupa m'miyendo, miyendo, kapena mapazi, kutopa kwambiri, kupuma pang'ono, komanso kusokonezeka. Kwa ana omwe amamwa mankhwalawa, pali chiopsezo chowonjezeka choti mudzakhala ndi vuto la impso mukadwala mukamamwa deferasirox ndikupanga kutsekula m'mimba, kusanza, malungo, kapena kusiya kumwa madzi nthawi zonse. Itanani dokotala wanu nthawi yomweyo ngati mukukumana ndi izi.

Deferasirox amathanso kuwononga chiwindi. Chiwopsezo choti chiwindi chimatha kuwonongeka chimakhala chachikulu ngati mutapitirira zaka 55, kapena ngati muli ndi matenda ena ovuta. Uzani dokotala wanu ngati mwakhalapo kapena mukudwala matenda a chiwindi. Mukakhala ndi zizindikiro zotsatirazi, itanani dokotala wanu mwachangu: khungu lachikaso kapena maso, zikwangwani ngati chimfine, kusowa mphamvu, kusowa kwa njala, kupweteka kumtunda kwakumanja kwam'mimba, kapena mabala kapena magazi osadziwika.

Deferasirox amathanso kuyambitsa magazi akulu kapena owopseza moyo m'mimba kapena m'matumbo. Chiwopsezo choti mutuluka magazi m'mimba kapena m'matumbo chingakhale chachikulu ngati ndinu okalamba, kapena mukudwala kwambiri chifukwa cha magazi. Uzani dokotala wanu ngati mwakhalapo ndi maplateleti ochepa (mtundu wa khungu lamagazi womwe umafunikira kuti muchepetse magazi), kapena ngati mukumwa mankhwala aliwonse awa: anticoagulants (oponda magazi) monga warfarin (Coumadin , Jantoven); aspirin kapena mankhwala ena osagwiritsa ntchito zotupa (NSAIDs) monga ibuprofen (Advil, Motrin, ena) ndi naproxen (Aleve, Naprosyn, ena); mankhwala ena olimbitsa mafupa kuphatikiza alendronate (Binosto, Fosamax), etidronate, ibandronate (Boniva), pamidronate, risedronate (Actonel, Atelvia), ndi zoledronic acid (Reclast, Zometa); kapena steroids monga dexamethasone, methylprednisolone (A-methapred, Depo-medrol, Medrol, Solu-medrol), kapena prednisone (Rayos). Ngati mukukumana ndi izi, itanani dokotala wanu nthawi yomweyo: kuwotcha m'mimba, masanzi ofiira kwambiri kapena owoneka ngati malo a khofi, magazi ofiira owoneka bwino, kapena mipando yakuda kapena yodikira.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso a labotale musanadye komanso mukamalandira chithandizo kuti muwone ngati zili bwino kuti mutenge deferasirox ndikuwona ngati mukukula zotsatirazi.

Deferasirox amagwiritsidwa ntchito pochizira achikulire ndi ana azaka ziwiri kapena kupitilira apo omwe ali ndi chitsulo chochuluka mthupi mwawo chifukwa adalandira magazi ambiri. Amagwiritsidwanso ntchito pochizira akuluakulu ndi ana azaka 10 kapena kupitilira apo omwe ali ndi chitsulo chochuluka mthupi mwawo chifukwa cha matenda amwazi wamagazi omwe amatchedwa thalassemia osadalira magazi (NTDT). Deferasirox ali mgulu la mankhwala otchedwa iron chelators. Imagwira ndikulumikiza chitsulo m'thupi kuti chitha kutulutsidwa (kuchotsedwa mthupi) mu ndowe.

Deferasirox imabwera ngati piritsi, granules, ndi piritsi loyimitsira (piritsi losungunuka m'madzi) kuti mutenge pakamwa. Imayenera kutengedwa m'mimba yopanda kanthu kamodzi patsiku, osachepera mphindi 30 musanadye, Mapiritsi ndi granules amathanso kutengedwa ndi chakudya chopepuka monga muffin wonse wa Chingerezi wokhala ndi odzola ndi mkaka wosalala, kapena sangweji yaying'ono pa mkate wonse wa tirigu. Tengani deferasirox mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani deferasirox ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Zinthu zosiyanasiyana za deferasirox zimalowetsedwa ndi thupi m'njira zosiyanasiyana ndipo sizingasinthane wina ndi mnzake. Ngati mukufuna kusintha kuchokera pa chinthu china cha deferasirox kupita china, dokotala angafunikire kusintha mlingo wanu. Nthawi iliyonse mukalandira mankhwala anu, onetsetsani kuti mwalandira mankhwala a deferasirox omwe adakulamulirani. Funsani wamankhwala wanu ngati simukudziwa kuti mwalandira mankhwala oyenera.

Pomeza mapiritsi a deferasirox (Jadenu) ndi madzi kapena madzi ena. Ngati mukuvutika kumeza piritsi, mutha kuphwanya piritsi ndikusakaniza ndi zakudya zofewa monga yogurt kapena maapulosi msanga musanadye. Komabe, musaphwanye piritsi la 90 mg (Jadenu) pogwiritsa ntchito chida chaphwanyidwa chomwe chasokonekera m'mbali.

Kuti mutenge deferasirox granules (Jadenu), perekani timadzuwa pa chakudya chofewa ngati yogurt kapena maapulosi msanga musanadye.

Kuti mutenge mapiritsi a deferasirox kuti ayimitsidwe (Exjade), tsatirani izi:

1. Nthawi zonse sungunulani mapiritsi oyimitsa madzi musanamwe. Osatafuna kapena kumeza mapiritsiwa kuti ayimitsidwe kwathunthu.
2. Ngati mukumwa zosakwana 1000 mg ya deferasirox, lembani chikho theka (pafupifupi 3.5 oz / 100 mL) ndi madzi, msuzi wa apulo, kapena madzi a lalanje. Ngati mukumwa zoposa 10 mg ya deferasirox, lembani kapu (pafupifupi 7 oz / 200 mL) ndi madzi, msuzi wa apulo, kapena msuzi wa lalanje. Ngati simukudziwa kuchuluka kwa deferasirox yomwe muyenera kumwa, funsani dokotala kapena wamankhwala.
3. Ikani chiwerengero cha mapiritsi omwe dokotala wanena kuti mutenge mu kapu.
4. Thirani madziwo kwa mphindi zitatu kuti asungunuke.
5. Imwani madziwo nthawi yomweyo.
6. Onjezerani pang'ono pokha mu kapu yopanda kanthu ndikuyambitsa. Sambani chikho kuti musungunuke mankhwala aliwonse omwe akadali mugalasi kapena pa oyambitsa.
7. Imwani madzi otsalawo.

Dokotala wanu amatha kusintha mlingo wanu wa deferasirox osapitilira kamodzi pa miyezi itatu kapena isanu ndi umodzi, kutengera zotsatira za mayeso anu a labotale.

Deferasirox amachotsa chitsulo chowonjezera m'thupi lanu pang'onopang'ono pakapita nthawi. Pitirizani kutenga deferasirox ngakhale mukumva bwino. Musaleke kumwa deferasirox osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge deferasirox,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la deferasirox, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a deferasirox, granules, kapena mapiritsi oyimitsa. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchula mankhwala omwe ali mgawo LOFUNIKITSA CHENJEZO ndi zina mwa izi: alosetron (Lotronex), aprepitant (Cinvanti, Emend), budesonide (Entocort, Pulmicort, Uceris, ku Symbicort), buspirone, cholestyramine (Prevalite), colesevelam (Welchol), colestipol (Colestid), conivaptan (Vaprisol), cyclosporine (Gengraf, Neoral, Sandimmune), darifenacin (Enablex), darunavir (Prezista, ku Prezcobix), dasatinib (Sprycel), dihydroergotamine (DHE 45, Migranalone (Multaq), duloxetine (Cymbalta), eletriptan (Relpax), eplerenone (Inspra), ergotamine (Ergomar, ku Cafergot, Migergot), everolimus (Afinitor, Zortress), felodipine, fentanyl (Actiq, Duragesic, Subsys, (Arnuity Ellipta, Flovent, ku Breo Ellipta, Advair), njira zolerera za mahomoni (mapiritsi oletsa kubereka, zigamba, mphete, kapena jakisoni), indinavir (Crixivan), lopinavir (ku Kaletra), lovastatin (Altoprev), lurasidone (Latuda), maravirococ (Selzentry), midazolam, nisoldipine (Sular), paclitax el (Abraxane, Taxol), phenytoin (Dilantin, Phenytek), phenobarbital, pimozide (Orap), quetiapine (Seroquel), quinidine (ku Nuedexta), ramelteon (Rozerem), repaglinide (Prandin, ku Prandimet), rifampin (Radampin) , ku Rifamate, ku Rifater), ritonavir (Norvir, ku Kaletra, Technivie, Viekira Pak), saquinavir (Invirase), sildenafil (Revatio, Viagra), simvastatin (Flolopid, Zocor, ku Vytorin), siroliumus (Rapamuneus), tacrol Astagraf, Envarsus, Prograf), theophylline (Theo-24), ticagrelor (Brilinta), tipranavir (Aptivus), tizanidine (Zanaflex), triazolam (Halcion), tolvaptan (Samsca), ndi vardenafil (Levitra, Staxyn). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa ma antiacids okhala ndi aluminiyamu monga Amphojel, Alternagel, Gaviscon, Maalox, kapena Mylanta, tengani maola 2 isanachitike kapena itatha deferasirox.
• uzani dokotala wanu pazogulitsa zomwe mukugwiritsa ntchito, makamaka melatonin, kapena zowonjezera za caffeine.
• uzani dokotala wanu ngati muli ndi myelodysplastic syndrome (vuto lalikulu la mafupa omwe ali pachiwopsezo chachikulu chotenga khansa), kapena khansa. Dokotala wanu angakuuzeni kuti musatenge deferasirox.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga deferasirox, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya pambuyo pake tsikulo, osachepera maola 2 mutatha kudya komaliza ndi mphindi 30 musanadye. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira kapena ngati simungathe kutenga deferasirox pamimba yopanda kanthu, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Deferasirox angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka m'mimba
• nseru
• kusanza
• kutsegula m'mimba

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena zomwe zatchulidwa mgulu la CHENJEZO LOFUNIKA, itanani dokotala wanu mwachangu:

• kutaya kumva
• mavuto owonera
• zidzolo, ming'oma, khungu kapena khungu lotupa, malungo, ma lymph node otupa
• kuvuta kupuma kapena kumeza; kutupa kwa nkhope, mmero, lilime, milomo, kapena maso; ukali
• kuvulaza kapena kutuluka mwachilendo

Deferasirox angayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• chikasu cha khungu kapena maso
• kupweteka kumtunda chakumanja kwam'mimba
• kuvulaza kapena kutuluka mwachilendo
• kusowa mphamvu
• kusowa chilakolako
• zizindikiro ngati chimfine
• kutsegula m'mimba
• nseru
• kusanza
• kuchepa pokodza
• kutupa kwa miyendo kapena akakolo

Sungani maimidwe onse ndi dokotala wanu. Muyenera kukhala ndi mayeso akumva ndi maso musanayambe deferasirox ndipo kamodzi pachaka mukamamwa mankhwalawa.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Kutuluka^®
• Jadenu^®