Jekeseni wa Certolizumab

Zamkati

• Jekeseni wa Certolizumab imagwiritsidwa ntchito kuthana ndi zizindikiritso zamavuto ena amthupi (momwe chitetezo cha mthupi chimagwirira mbali zabwino za thupi ndikupangitsa kupweteka, kutupa, ndi kuwonongeka) kuphatikiza izi:
• Musanagwiritse ntchito jakisoni wa certolizumab,
• Jekeseni wa Certolizumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

Jekeseni wa Certolizumab ungachepetse kuthekera kwanu kothana ndi matenda ndikuwonjezera chiopsezo choti mutenge matenda owopsa kapena owopsa kuphatikizira matenda a fungus, bakiteriya, ndi ma virus omwe angafalikire m'thupi. Matendawa angafunike kuthandizidwa kuchipatala ndipo atha kupha. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati muli kapena mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera ndikadutsa (monga zilonda zozizira), ndi matenda opatsirana omwe samatha. Komanso muuzeni dokotala ngati mwakhalapo ndi matenda a shuga, hepatitis B (matenda opatsirana omwe amakhudza chiwindi), kachilombo ka HIV, kapena vuto lililonse lomwe limakhudza chitetezo cha mthupi lanu, komanso ngati mumakhala kapena munakhalapo madera monga zigwa za Mtsinje wa Ohio ndi Mississippi komwe matenda ofala a mafangasi amafala kwambiri. Funsani dokotala wanu ngati simukudziwa ngati matendawa amapezeka ponseponse m'dera lanu. Uzani dokotala wanu ngati mukumwa mankhwala omwe amachepetsa chitetezo cha mthupi monga abatacept (Orencia), adalimumab (Humira), anakinra (Kineret), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), methotrexate ( Otrexup, Rasuvo, Trexall), natalizumab (Tysabri), rituximab (Rituxan), steroids kuphatikizapo dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), ndi prednisone (Rayos), ndi tocilizumab (Actemra).

Dokotala wanu adzakuyang'anirani ngati muli ndi matendawa mukamalandira chithandizo chake. Ngati muli ndi zizindikiro zotsatirazi musanayambe kumwa mankhwala kapena ngati mukukumana ndi zizindikiro zotsatirazi mukamalandira chithandizo kapena mutangochira kumene, itanani dokotala wanu nthawi yomweyo: zilonda zapakhosi; chifuwa; kutsokomola ntchofu zamagazi; malungo; kupweteka m'mimba; kutsegula m'mimba; zizindikiro ngati chimfine; mabala otseguka kapena zilonda; kuonda; kufooka; thukuta; kuvuta kupuma; kukodza kovuta, pafupipafupi, kapena kupweteka; kapena zizindikiro zina za matenda.

Mutha kukhala kuti mwadwala kale chifuwa chachikulu (TB; matenda owopsa am'mapapo) kapena hepatitis B (kachilombo kamene kamakhudza chiwindi) koma mulibe zizindikiro zilizonse za matendawa. Poterepa, kugwiritsa ntchito jakisoni wa certolizumab kumatha kupangitsa kuti matenda anu akhale owopsa ndikupangitsani kukhala ndi zizindikilo. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB kosagwira ntchito ndipo atha kuyitanitsa kuyesa magazi kuti muwone ngati muli ndi matenda a hepatitis B osagwira ntchito. Ngati ndi kotheka, dokotala wanu adzakupatsani mankhwala ochizira matendawa musanayambe kugwiritsa ntchito certolizumab. Uzani dokotala ngati mwadwalapo kapena munakhalapo ndi TB, ngati munakhalako kapena munapitako kudziko kumene TB imafala, kapena ngati munakhalapo ndi munthu amene ali ndi TB. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati muli ndi zina mwazizindikiro mukumwa mankhwala, pitani kuchipatala mwachangu: chifuwa, kuonda, kuchepa kwa minofu, kapena malungo. Komanso itanani dokotala wanu nthawi yomweyo ngati muli ndi zina mwazizindikiro za matenda a chiwindi a B kapena ngati muli ndi zina mwazizindikiro mukalandira kapena mutalandira chithandizo: kutopa kwambiri, khungu lachikaso kapena maso, kusowa chilakolako chambiri, nseru kapena kusanza, kupweteka kwa minofu, mkodzo wamdima, matumbo ofiira dongo, malungo, kuzizira, kupweteka m'mimba, kapena zotupa.

Ana ndi achinyamata ena omwe adalandira mankhwala ofanana ndi jakisoni wa certolizumab adayamba khansa yoopsa kapena yowopsa kuphatikizapo lymphoma (khansa yomwe imayamba m'maselo omwe amalimbana ndi matenda). Ana ndi achinyamata sayenera kulandira jakisoni wa certolizumab, koma nthawi zina, dokotala amatha kusankha kuti jakisoni wa certolizumab ndiye mankhwala abwino kwambiri ochizira matenda a mwana. Ngati jakisoni wa certolizumab wapatsidwa kwa mwana wanu, muyenera kulankhula ndi dokotala wa mwana wanu za kuopsa ndi zabwino zogwiritsa ntchito mankhwalawa. Mwana wanu akayamba kudwala matendawa, itanani dokotala wake mwachangu: kuonda kosadziwika; zotupa zotupa pakhosi, pansi, kapena kubuula; kapena kuvulaza kosavuta kapena kutuluka magazi.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa certolizumab ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito jakisoni wa certolizumab.

Jekeseni wa Certolizumab imagwiritsidwa ntchito kuthana ndi zizindikiritso zamavuto ena amthupi (momwe chitetezo cha mthupi chimagwirira mbali zabwino za thupi ndikupangitsa kupweteka, kutupa, ndi kuwonongeka) kuphatikiza izi:

• Matenda a Crohn (matenda omwe thupi limagwiritsa ntchito gawo la m'mimba, kumayambitsa kupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) zomwe sizinasinthe mukamalandira mankhwala ena,
• nyamakazi ya nyamakazi (momwe thupi limagwirira ziwalo zake, zimapweteka, kutupa, komanso kutayika kwa ntchito),
• psoriatic nyamakazi (vuto lomwe limayambitsa kupweteka kwamagulu ndi kutupa ndi masikelo pakhungu),
• ankylosing spondylitis yogwira (momwe thupi limagwirira malo olumikizana ndi msana ndi madera ena omwe amayambitsa kupweteka, kutupa, ndi kuwonongeka kwamagulu) ndikusintha komwe kumawoneka pa X-ray,
• yogwira non-radiographic axial spondyloarthritis (momwe thupi limagwirira malo olumikizirana mafupa a msana ndi madera ena omwe amachititsa ululu ndi zizindikilo zotupa), koma osasintha pa X-ray,
• plaque psoriasis (matenda apakhungu pomwe pamakhala zigamba zofiira pamiyendo ina m'thupi) mwa anthu omwe atha kupindula ndi mankhwala kapena Phototherapy (mankhwala omwe amaphatikiza khungu ndi kuwala kwa ultraviolet).

Jekeseni ya Certolizumab ili mgulu la mankhwala otchedwa tumor necrosis factor (TNF) inhibitors. Zimagwira ntchito poletsa ntchito ya TNF, chinthu m'thupi chomwe chimayambitsa kutupa.

Jekeseni wa Certolizumab umabwera ngati ufa wosakanizidwa ndi madzi osabereka ndikujambulidwa subcutaneously (pansi pa khungu) ndi dokotala kapena namwino kuofesi ya zamankhwala komanso ngati jekeseni lodzaza kale lomwe mutha kubaya pansi pokha kunyumba. Pamene jakisoni wa certolizumab amagwiritsidwa ntchito pochiza matenda a Crohn, nthawi zambiri amaperekedwa milungu iwiri iliyonse pamlingo woyamba woyamba ndiyeno milungu inayi iliyonse bola chithandizo chikapitirire. Pamene jakisoni wa certolizumab amagwiritsidwa ntchito pochiza nyamakazi ya nyamakazi, psoriatic nyamakazi, ankylosing spondylitis, kapena axial spondyloarthritis, nthawi zambiri imaperekedwa milungu iwiri iliyonse pamayeso atatu oyamba ndiyeno milungu iwiri kapena inayi bola chithandizo chikapitirire. Jekeseni ya certolizumab ikagwiritsidwa ntchito pochizira plaque psoriasis, imaperekedwa kwamasabata awiri aliwonse. Ngati mukubaya jekeseni wa certolizumab nokha, tsatirani malangizo mosamala pa cholembera chanu. Osabayikira certolizumab yochulukirapo kuposa momwe adanenera dokotala.

Ngati mukubaya jekeseni wa certolizumab nokha kunyumba kapena kukhala ndi mnzanu kapena wachibale akubayirani mankhwalawo, funsani dokotala wanu kuti akuwonetseni kapena munthu amene akumubaya mankhwalawo kuti amubayire. Inu ndi munthu amene mukubaya mankhwalawo muyeneranso kuwerenga malangizo omwe agwiritsidwe ntchito omwe amabwera ndi mankhwalawo.

Musanatsegule phukusi lomwe lili ndi mankhwala anu, onetsetsani kuti phukusilo silinang'ambike, kuti zisindikizo zowoneka bwino pamwamba ndi pansi pa phukusili sizikusowa kapena kusweka komanso kuti tsiku lomaliza lakusindikizidwa phukusili silinachitike wadutsa. Mukatsegula phukusili, yang'anani mosamala madzi omwe ali mu syringe. Madziwo ayenera kukhala oyera kapena otumbululuka achikasu ndipo sayenera kukhala ndi tinthu tating'ono tambiri. Itanani wamankhwala wanu, ngati pali zovuta zilizonse ndi phukusi kapena syringe. Osabaya mankhwala.

Mutha kubaya jekeseni wa certolizumab paliponse m'mimba kapena ntchafu kupatula mchombo wanu (batani lamimba) ndi dera mainchesi awiri mozungulira. Osabaya mankhwalawo pakhungu lofewa, lophwanyika, lofiira, kapena lolimba, kapena lomwe lili ndi zipsera kapena zotambasula. Osabaya mankhwala pamalo amodzi kangapo. Sankhani malo atsopano osachepera inchi imodzi kuchokera pomwe mudagwiritsa ntchito nthawi iliyonse mukabaya mankhwala. Ngati dokotala wakuwuzani kuti mubayire masirinji awiri a certolizumab pamlingo uliwonse, sankhani malo osiyana a jakisoni aliyense.

Musagwiritsenso ntchito ma syringeum odzaza kale a certolizumab ndipo musabwererenso ma syringe mukatha kugwiritsa ntchito. Tayani majakisoni ogwiritsidwira ntchito m'chidebe chosagwira. Funsani wamankhwala wanu momwe angatayire chidebecho.

Jekeseni wa Certolizumab itha kuthandizira kuwongolera zizindikilo zanu, koma sizingathetse vuto lanu. Osasiya kugwiritsa ntchito jakisoni wa certolizumab osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanagwiritse ntchito jakisoni wa certolizumab,

• uzani adotolo ndi wamankhwala ngati simukugwirizana ndi jakisoni wa certolizumab; Mankhwala ena aliwonse, lalabala kapena labala, kapena chilichonse chosakaniza mu jakisoni wa certolizumab. Funsani wamankhwala wanu kapena onani chitsogozo cha mankhwala kuti muwone mndandanda wazosakaniza. Ngati mukugwiritsa ntchito jakisoni woyambira kale, uzani dokotala ngati inu kapena munthu amene mukubaya jakisoni wa mankhwalawa ali ndi vuto la latex.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo mankhwala omwe atchulidwa mgulu la CHENJEZO LOFUNIKA. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhalapo ndi matenda omwe amakhudza dongosolo lanu lamanjenje, monga multiple sclerosis (MS; matenda omwe misempha sagwira ntchito moyenera imayambitsa kufooka, kufooka, kutayika kwa kulumikizana kwa minofu ndi mavuto ndi masomphenya, kulankhula , ndi chikhodzodzo) Matenda a Guillain-Barré (kufooka, kumva kulira, ndi ziwalo zotheka chifukwa cha kuwonongeka kwamitsempha mwadzidzidzi) kapena optic neuritis (kutupa kwa mitsempha yomwe imatumiza mauthenga kuchokera kumaso kupita kuubongo); dzanzi, kutentha, kapena kumva kulasalasa m'mbali iliyonse ya thupi lanu; kugwidwa; mtima kulephera; khansa yamtundu uliwonse; kapena mavuto otaya magazi kapena matenda omwe amakhudza magazi anu.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukamagwiritsa ntchito jakisoni wa certolizumab, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni yamano, uzani adotolo kapena dokotala kuti mukugwiritsa ntchito jakisoni wa certolizumab.
• mulibe katemera popanda kulankhula ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni mlingo womwe mwaphonya mukangokumbukira. Ngati ili pafupi nthawi ya mlingo wanu wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Osabaya jakisoni kawiri kuti mupange yomwe mwaphonya.

Jekeseni wa Certolizumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kufiira, kuyabwa, kupweteka, kapena kutupa pamalo obayira
• mutu
• kupweteka kwa msana

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• kupuma movutikira
• zovuta kumeza kapena kupuma
• kupweteka pachifuwa
• kunenepa mwadzidzidzi
• ming'oma
• kutentha kotentha
• chizungulire kapena kukomoka
• zidzolo, makamaka masaya kapena mikono yomwe imakulira padzuwa
• kuvulaza kapena kutuluka mwachilendo
• khungu lotumbululuka
• khungu lotupa
• kutopa kwambiri
• dzanzi kapena kumva kulasalasa
• mavuto ndi masomphenya
• kufooka m'manja kapena m'miyendo
• kupweteka pamodzi
• kusowa chilakolako
• zigamba zofiira ndi zopukutira pakhungu

Akuluakulu omwe amalandira jakisoni wa certolizumab atha kukhala ndi khansa yapakhungu, lymphoma, ndi mitundu ina ya khansa kuposa anthu omwe salandila jakisoni wa certolizumab. Lankhulani ndi dokotala wanu za kuopsa kolandira mankhwalawa.

Jekeseni wa Certolizumab ingayambitse zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mabotolo ndi ma syringe oyikiratu mu katoni yoyambirira yomwe idawateteza ku kuwala komanso kosafikirika ndi ana. Sungani jakisoni wa certolizumab mufiriji ndipo musazime.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu lingayankhire jakisoni wa certolizumab.

Musanayesedwe labotale, uzani adotolo ndi omwe akuwagwiritsa ntchito kuti mukugwiritsa ntchito jakisoni wa certolizumab.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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