Eltrombopag

Zamkati

• Musanatenge eltrombopag,
• Eltrombopag ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Ngati muli ndi matenda otupa chiwindi a C (matenda opatsirana omwe amatha kuwononga chiwindi) ndipo mumamwa eltrombopag ndi mankhwala a hepatitis C otchedwa interferon (Peginterferon, Pegintron, ena) ndi ribavirin (Copegus, Rebetol, Ribasphere, ena), pali chiopsezo chowonjezeka kuti mutha kuwonongeka chiwindi. Ngati mukukumana ndi izi, itanani dokotala wanu mwachangu: chikaso cha khungu kapena maso, mkodzo wakuda, kutopa kwambiri, kupweteka kumtunda chakumanja kwam'mimba, kutupa kwa m'mimba, kapena kusokonezeka.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labotale musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira pa eltrombopag.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi eltrombopag ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kotenga eltrombopag.

Eltrombopag imagwiritsidwa ntchito kuonjezera kuchuluka kwa ma platelet (maselo omwe amathandiza magazi kuundana) kuti achepetse mwayi wotaya magazi mwa akulu ndi ana azaka 1 kapena kupitilira apo omwe ali ndi immune thrombocytopenia (ITP; vuto lomwe lingayambitse zipsera zosazolowereka kapena Kutuluka magazi chifukwa cha kuchuluka kwa magazi othandiza magazi kuundana m'magazi) komanso omwe sanathandizidwe kapena kuchiritsidwa ndi mankhwala ena, kuphatikiza mankhwala kapena opareshoni yochotsa ndulu. Eltrombopag imagwiritsidwanso ntchito kukulitsa kuchuluka kwa ma platelet mwa anthu omwe ali ndi hepatitis C (matenda omwe amawononga chiwindi) kuti athe kuyamba ndikupitiliza kulandira chithandizo ndi interferon (Peginterferon, Pegintron, ena) ndi ribavirin (Rebetol). Eltrombopag imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuti athetse kuchepa kwa magazi m'thupi (momwe thupi silimapangira maselo amwazi okwanira) mwa akulu ndi ana azaka ziwiri kapena kupitilira apo. Amagwiritsidwanso ntchito kuthana ndi kuchepa kwa magazi m'thupi mwa akulu omwe sanathandizidwe ndi mankhwala ena. Eltrombopag imagwiritsidwa ntchito kuonjezera kuchuluka kwa ma platelet okwanira kuti muchepetse magazi omwe amapezeka ndi anthu omwe ali ndi ITP kapena aplastic anemia, kapena kulola chithandizo ndi interferon ndi ribavirin mwa anthu omwe ali ndi hepatitis C. Komabe sikuti imagwiritsidwa ntchito kuonjezera kuchuluka kwa ma platelet mulingo wabwinobwino. Eltrombopag sayenera kugwiritsidwa ntchito pochizira anthu omwe ali ndi ma platelet ochepa chifukwa cha zinthu zina kupatula ITP, hepatitis C, kapena aplastic anemia. Eltrombopag ali mgulu la mankhwala otchedwa thrombopoietin receptor agonists. Zimagwira ntchito popangitsa ma cell am'mafupa kupanga ma platelet ambiri.

Eltrombopag imabwera ngati piritsi komanso ngati ufa wothira pakamwa (madzi) kuti mutenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku wopanda kanthu, osachepera ola limodzi musanadye kapena maola awiri mutadya. Tengani eltrombopag mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani eltrombopag chimodzimodzi monga mwawuzidwa. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Tengani eltrombopag osachepera maola 2 musanadye kapena maola 4 mutadya kapena kumwa zakudya zomwe zili ndi calcium yambiri, monga mkaka, timadziti tokhala ndi calcium, chimanga, oatmeal, ndi buledi; nsomba ya trauti; ngale; masamba obiriwira monga sipinachi ndi masamba obiriwira; ndi tofu ndi zinthu zina za soya. Funsani dokotala wanu ngati simukudziwa ngati chakudya chili ndi calcium yambiri. Mutha kupeza zothandiza kutenga eltrombopag pafupi kumayambiriro kapena kumapeto kwa tsiku lanu kuti muzitha kudya izi nthawi zambiri mukadzuka.

Kumeza mapiritsi lonse. Osagawanika, kutafuna, kapena kuwaphwanya ndikuwasakaniza ndi chakudya kapena zakumwa.

Ngati mukumwa ufawu kuti muyimitse pakamwa, werengani mosamala malangizo a wopanga kuti agwiritse ntchito omwe amabwera ndi mankhwalawa. Malangizowa amafotokoza momwe mungakonzekerere ndikuyeza mlingo wanu. Sakanizani ufa ndi madzi ozizira kapena ozizira musanagwiritse ntchito. Osasakaniza ufa ndi madzi otentha. Atangotha ​​kukonzekera, kumeza mlingo. Ngati satengedwa mkati mwa mphindi 30 kapena ngati pali madzi otsala, tulutsani zosakanizazo mu zinyalala (musatsanulire pansi pake).

Musalole kuti ufa ufike pakhungu lanu. Mukathira utsi pakhungu lanu, mutsukeni msanga ndi sopo. Itanani dokotala wanu ngati muli ndi khungu kapena ngati muli ndi mafunso.

Dokotala wanu mwina angakuyambitseni pamlingo wochepa wa eltrombopag ndikusintha mlingo wanu kutengera yankho lanu ku mankhwalawo. Kumayambiriro kwa chithandizo chanu, adokotala amalamula kuti mukayezetse magazi kuti muwone kuchuluka kwa magazi anu kamodzi sabata iliyonse. Dokotala wanu akhoza kukulitsa mlingo wanu ngati mulingo wanu wamagazi ndi wotsika kwambiri. Ngati mulingo wanu wamagazi ndiwokwera kwambiri, dokotala akhoza kuchepetsa mlingo wanu kapena sangakupatseni eltrombopag kwakanthawi. Pambuyo poti chithandizo chanu chapitilira kwakanthawi ndipo dokotala wanu wapeza mulingo wa eltrombopag womwe umakugwirirani ntchito, mulingo wanu wamagazi uzayang'aniridwa kangapo. Mulingo wanu wamaplatelet udzawunikidwanso sabata iliyonse kwa masabata osachepera 4 mutasiya kumwa eltrombopag.

Ngati muli ndi ITP yanthawi yayitali, mutha kulandira mankhwala ena othandizira matenda anu komanso eltrombopag. Dokotala wanu akhoza kuchepetsa kuchuluka kwa mankhwalawa ngati eltrombopag ikukuthandizani.

Eltrombopag sagwira ntchito kwa aliyense. Ngati mulingo wanu wam'madzi sukulira mokwanira mutatenga eltrombopag kwakanthawi, dokotala wanu angakuuzeni kuti musiye kumwa eltrombopag.

Eltrombopag itha kuthandizira kuwongolera matenda anu koma singachiritse. Pitirizani kutenga eltrombopag ngakhale mukumva bwino. Osasiya kumwa eltrombopag osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge eltrombopag,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la eltrombopag, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a eltrombopag. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants (opopera magazi) monga warfarin (Coumadin, Jantoven); chifuwa (Tracleer); mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor, ku Caduet), fluvastatin (Lescol), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), ndi simvastatin (Zocor, Flolopid, ku Vytorin); ezetimibe (Zetia, mu Vytorin); glyburide (Diabeta, Glynase); imatinib (Gleevec); irinotecan (Camptosar, Onivyde); olmesartan (Benicar, ku Azor, ku Tribenzor); lapatinib (Tykerb); methotrexate (Rasuvo, Trexall, ena); mitochantrone; repaglinide (Prandin): rifampin (Rimactane, Rifadin, ku Rifamate, Rifater); sulfasalazine (Azulfidine); topotecan (Hycamtin), ndi valsartan (Diovan, ku Byvalson, ku Entresto, ku Exforge). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.Mankhwala ena ambiri amathanso kulumikizana ndi eltrombopag, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• ngati mukumwa maantacid okhala ndi calcium, aluminium, kapena magnesium (Maalox, Mylanta, Tums) kapena mavitamini kapena mchere wonongera okhala ndi calcium, iron, zinc kapena selenium, tengani eltrombopag 2 hours isanakwane kapena maola 4 mutamwa.
• uzani adotolo ngati muli ochokera ku East Asia (Chinese, Japan, Taiwan, kapena Korea) ndipo ngati mwakhalapo ndi cataract (mitambo yamaso ya diso yomwe ingayambitse mavuto a masomphenya), kuundana kwa magazi, vuto lililonse zomwe zimawonjezera chiopsezo kuti mudzadwala magazi, kutuluka magazi, myelodysplastic syndrome (MDS; matenda amwazi omwe angayambitse khansa), kapena matenda a chiwindi. Muuzeni dokotala ngati mwachitidwapo opaleshoni kuti muchotse nthenda yanu.
• Uzani dokotala wanu ngati muli ndi pakati, kapena konzekerani kutenga pakati. Simuyenera kutenga pakati mukamamwa ndi eltrombopag. Gwiritsani ntchito njira yolerera pamene mukulandira chithandizo komanso masiku 7 mutatha kumwa mankhwala. Mukakhala ndi pakati mukatenga eltrombopag, itanani dokotala wanu.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa eltrombopag.
• pitilizani kupewa zinthu zomwe zitha kuvulaza ndikutuluka magazi mukamalandira chithandizo cha eltrombopag. Eltrombopag imaperekedwa kuti ichepetse chiopsezo choti mudzakhala ndi magazi ambiri, komabe pali chiopsezo kuti kutuluka magazi kumatha kuchitika.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya. Musatenge mlingo umodzi wa eltrombopag tsiku limodzi.

Eltrombopag ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka kwa msana
• kupweteka kwa minofu
• mutu
• Zizindikiro za chimfine monga malungo, mutu, zilonda zapakhosi, chifuwa, kutopa, kuzizira, komanso kupweteka kwa thupi
• kufooka
• kutopa kwambiri
• kuchepa kudya
• kupweteka kapena kutupa pakamwa kapena pakhosi
• kutayika tsitsi
• zidzolo
• khungu limasintha
• kuyabwa pakhungu, kuyabwa, kapena kutentha
• kutupa kwa akakolo, mapazi, kapena miyendo yakumunsi
• kupweteka kwa mano (mwa ana)

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kutupa, kupweteka, kukoma mtima, kutentha kapena kufiira mwendo umodzi
• kupuma pang'ono, kutsokomola magazi, kugunda kwamtima, kupuma mwachangu, kupweteka mukamapuma kwambiri
• kupweteka pachifuwa, mikono, kumbuyo, khosi, nsagwada, kapena m'mimba, kutuluka thukuta lozizira, mutu wopepuka
• kulankhula pang'onopang'ono kapena kovuta, kufooka mwadzidzidzi kapena kufooka kwa nkhope, mkono kapena mwendo, kupweteka mwadzidzidzi, mavuto owonera mwadzidzidzi, kuyenda movutikira
• kupweteka m'mimba, nseru, kusanza, kutsegula m'mimba
• mitambo, masomphenya, kapena masomphenya ena amasintha

Eltrombopag ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Ngati mankhwala anu abwera ndi paketi ya desiccant (paketi yaying'ono yomwe ili ndi chinthu chomwe chimatenga chinyezi kuti mankhwala asamaume), siyani paketiyo mu botolo koma samalani kuti musayimeze.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• zidzolo
• kuchepa kwa mtima
• kutopa kwambiri

Dokotala wanu amalamula kuti muyesedwe diso musanachitike komanso mukamalandira chithandizo cha eltrombopag.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Malangizo^®