Saxagliptin

Zamkati

• Musanayambe kumwa saxagliptin,
• Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
• Saxagliptin imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa saxagliptin ndipo itanani dokotala nthawi yomweyo:

Saxagliptin imagwiritsidwa ntchito limodzi ndi zakudya komanso masewera olimbitsa thupi kuti muchepetse shuga m'magazi a odwala matenda ashuga amtundu wa 2 (momwe shuga wamagazi amakhala wochuluka kwambiri chifukwa thupi silimatulutsa kapena kugwiritsa ntchito insulini mwachizolowezi). Saxagliptin ali mgulu la mankhwala otchedwa dipeptidyl peptidase-4 (DPP-4) inhibitors. Zimagwira ntchito pakuwonjezera kuchuluka kwa insulini yopangidwa ndi thupi mukatha kudya mukamafinya shuga. Saxagliptin sagwiritsidwa ntchito pochiza matenda ashuga amtundu wa 1 (momwe thupi silimatulutsa insulin motero, silingathe kuwongolera kuchuluka kwa shuga m'magazi) kapena matenda ashuga ketoacidosis (vuto lalikulu lomwe lingachitike ngati shuga wa magazi sanalandiridwe mankhwala ).

Popita nthawi, anthu omwe ali ndi matenda ashuga komanso shuga wambiri m'magazi amatha kukhala ndi mavuto owopsa kapena owopsa, kuphatikizapo matenda amtima, sitiroko, mavuto a impso, kuwonongeka kwa mitsempha, komanso mavuto amaso. Kumwa mankhwala (mankhwala), kusintha moyo wanu (mwachitsanzo, zakudya, kuchita masewera olimbitsa thupi, kusiya kusuta), komanso kuwunika shuga wanu wamagazi pafupipafupi kungakuthandizeni kuthana ndi matenda anu ashuga komanso kukhala ndi thanzi labwino. Mankhwalawa amathanso kuchepetsa mwayi wokhala ndi vuto la mtima, sitiroko, kapena zovuta zina zokhudzana ndi matenda ashuga monga impso kulephera, kuwonongeka kwamitsempha (dzanzi, miyendo yozizira kapena mapazi; kuchepa kwa kugonana kwa amuna ndi akazi), mavuto amaso, kuphatikiza kusintha kutaya masomphenya, kapena matenda a chiseyeye. Dokotala wanu ndi ena othandizira zaumoyo adzakambirana nanu za njira yabwino yothetsera matenda anu ashuga.

Saxagliptin imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Tengani saxagliptin mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani saxagliptin ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Saxagliptin imayang'anira mtundu wa 2 shuga koma samachiritsa. Pitirizani kumwa saxagliptin ngakhale mutakhala bwino. Osasiya kumwa saxagliptin osalankhula ndi dokotala.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba mankhwala ndi saxagliptin ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanayambe kumwa saxagliptin,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la saxagliptin, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a saxagliptin. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala ena oletsa mafangasi monga itraconazole (Onmel, Sporanox) ndi ketoconazole (Nizoral); clarithromycin (Biaxin); mankhwala ena a kachilombo ka HIV (kachilombo ka HIV m'thupi) kapena Edzi (matenda opatsirana m'thupi) monga atazanavir (Reyataz, ku Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); insulin kapena mankhwala am'kamwa a matenda ashuga monga chlorpropamide (Diabinese), glimepiride (Amaryl, ku Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, ku Glucovance), nateglinide (Starlix), pioglitazone (Actos, ku Actoplus Met, ku Duetact), repaglinide (Prandin, ku Prandimet), rosiglitazone (Avandia), tolazamide, ndi tolbutamide; nefazodone; ndi telithromycin (sikupezeka ku US; Ketek). Inu dokotala mungafunike kusintha mlingo wa mankhwala anu kapena kukuyang'anirani mosamala za zotsatirapo zake.
• auzeni adotolo ngati mumamwa kapena mudamwa mowa wambiri, ngati mwakhalapo ndi kapamba (kutupa kwa kapamba), miyala yamiyala, milingo yayikulu ya triglycerides (mafuta) m'magazi anu, kulephera kwa mtima, matenda ashuga ketoacidosis, kapena matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga saxagliptin, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa saxagliptin.
• lankhulani ndi dokotala wanu zomwe muyenera kuchita mukavulala kapena mutakhala ndi malungo kapena matenda. Izi zitha kukhudza shuga wamagazi komanso kuchuluka kwa saxagliptin yomwe mungafune.

Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Ndikofunika kudya chakudya chopatsa thanzi, kuchita masewera olimbitsa thupi nthawi zonse, komanso kuonda ngati kuli kofunikira. Izi zidzakuthandizani kuchepetsa matenda anu ashuga ndikuthandizira saxagliptin kugwira bwino ntchito.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange chosowacho pokhapokha dokotala atakuuzani kuti muyenera kutero.

Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.

Saxagliptin imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• chikhure
• mutu
• kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, siyani kumwa saxagliptin ndipo itanani dokotala nthawi yomweyo:

• zidzolo
• ming'oma
• khungu khungu
• kuyabwa
• kutupa kwa nkhope, milomo, lilime kapena pakhosi
• kuvuta kupuma kapena kumeza
• ukali
• kupweteka kosalekeza, komwe kumayambira kumtunda kumanzere kapena pakati pamimba koma kumafalikira kumbuyo
• kusanza
• kusowa chilakolako
• kutopa kwambiri
• kupuma movutikira, makamaka akagona pansi
• kutupa kwa mapazi, akakolo, kapena miyendo
• kunenepa mwadzidzidzi

Saxagliptin ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu atha kuyitanitsa mayeso ena a labotale musanadye komanso mukamalandira chithandizo cha saxagliptin kuti muwone momwe thupi lanu lingayankhire. Magazi anu a shuga ndi hemoglobin (HbA1c) a glycosylated amayenera kufufuzidwa pafupipafupi kuti mudziwe momwe mungayankhire kwa saxagliptin. Dokotala wanu amathanso kukuuzani momwe mungayang'anire kuyankha kwanu ku saxagliptin poyesa magazi anu kapena shuga wamkodzo kunyumba. Tsatirani malangizowa mosamala.

Muyenera kuvala chibangili chizindikiritso cha ashuga kuti mutsimikizire kuti mumalandira chithandizo chadzidzidzi pakagwa mwadzidzidzi.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Onglyza^®

• Kombiglyze^® XR (yokhala ndi Metformin, Saxagliptin)
• Qtern^® (yokhala ndi Dapagliflozin, Saxagliptin)
• Zovuta^® XR (yokhala ndi Dapagliflozin, Metformin, Saxagliptin)