Jekeseni wa Ustekinumab

Zamkati

• Asanalandire jekeseni wa ustekinumab,
• Jekeseni wa Ustekinumab imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la MAWONEKEDWE OTHANDIZA, pitani kuchipatala nthawi yomweyo:

Jekeseni wa Ustekinumab imagwiritsidwa ntchito pochizira zolembera zapakhosi psoriasis (matenda akhungu momwe mawonekedwe ofiira ofiira amatuluka m'malo ena amthupi) mwa akulu ndi ana azaka 6 kapena kupitilira apo omwe atha kupindula ndi mankhwala kapena phototherapy (chithandizo chomwe chimaphatikizapo kuwulula khungu ku kuwala kwa ultraviolet). Amagwiritsidwanso ntchito payekha kapena kuphatikiza methotrexate (Otrexup, Rasuvo, Trexall) kuchiza nyamakazi ya psoriatic (vuto lomwe limayambitsa kupweteka kwa mafupa ndi kutupa ndi mamba pakhungu) mwa akulu. Jekeseni wa Ustekinumab imagwiritsidwanso ntchito pochiza matenda a Crohn's (vuto lomwe thupi limagwiritsa ntchito ulusi wam'mimba, ndikupweteka, kutsegula m'mimba, kuchepa thupi, ndi malungo) mwa akulu. Jekeseni wa Ustekinumab imagwiritsidwanso ntchito pochizira ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda m'kati mwa kholingo [matumbo akulu] ndi rectum) mwa akulu. Jekeseni wa Ustekinumab ili mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira mwa kuyimitsa zochita za maselo ena m'thupi omwe amayambitsa zizindikiro za plaque psoriasis, psoriatic arthritis, matenda a Crohn, ndi ulcerative colitis.

Ustekinumab imabwera ngati yankho (madzi) jakisoni subcutaneous (pansi pa khungu) kapena kudzera m'mitsempha (mumtsempha). Pofuna kuchiza plaque psoriasis ndi psoriatic nyamakazi, nthawi zambiri amabayidwa mosavomerezeka milungu isanu ndi inayi pamiyeso iwiri yoyambirira kenako masabata khumi ndi awiri bola chithandizo chikapitirire. Pofuna kuchiza matenda a Crohn's and ulcerative colitis, nthawi zambiri amabayidwa kudzera m'mitsempha yamankhwala oyamba ndiyeno amapatsidwa subcutaneously milungu isanu ndi itatu iliyonse bola chithandizo chikapitirire.

Mulandila jakisoni woyamba wanu subcutaneous wa ustekinumab jekeseni mu ofesi ya dokotala wanu. Pambuyo pake, dokotala wanu akhoza kupitiliza kukupatsani jakisoni kapena kukulolani kuti mudzilowetse jekeseni wa ustekinumab nokha kapena kuti wosamalira azibaya jakisoni. Funsani dokotala wanu kapena wamankhwala kuti akuwonetseni inu kapena munthu yemwe akukhala jakisoni momwe angabayire ustekinumab. Musanagwiritse ntchito jekeseni wa ustekinumab nokha nthawi yoyamba, werengani malangizo olembedwa omwe amabwera nawo.

Ngati mankhwala anu abwera mu syringe kapena botolo loyambirira, gwiritsani ntchito sirinji kapena botolo kamodzi kokha ndikujambulitsa yankho lonse mu syringe. Ngakhale pangakhale yankho lomwe latsala mu syringe kapena chipangizocho, musachigwiritsenso ntchito. Kutaya singano zogwiritsidwa ntchito kale, ma syringe, ndi zida mu chidebe chosagundika. Lankhulani ndi dokotala wanu kapena wamankhwala za momwe mungatayire chidebe chosagwira mankhwala.

Musagwedezeke syringe kapena botolo lomwe lili ndi ustekinumab.

Nthawi zonse yang'anani yankho la ustekinumab musanaibayize. Onetsetsani kuti tsiku lomaliza ladutsa komanso kuti madziwo ndiwowoneka bwino kapena wachikaso pang'ono. Madziwo amatha kukhala ndi tinthu tating'onoting'ono toyera. Musagwiritse ntchito syringe kapena botolo loyikamo kale ngati lawonongeka, latha ntchito, lazizira, kapena ngati madzi ali mitambo kapena ali ndi tinthu tating'ono.

Mutha kubaya jekeseni wa ustekinumab mosadukiza paliponse patsogolo pa ntchafu yanu (mwendo wapamwamba), mikono yakunja, matako, kapena mimba (m'mimba) kupatula mchombo wanu ndi dera lamasentimita asanu mozungulira. Kuti muchepetse mwayi wowawa kapena kufiira, gwiritsani ntchito tsamba lina la jakisoni aliyense. Osalowetsa malo omwe khungu ndi lofewa, lophwanyika, lofiira, kapena lolimba kapena komwe muli ndi zipsera kapena zotambasula.

Dokotala wanu kapena wazamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa ustekinumab. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jekeseni wa ustekinumab,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi ustekinumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jekeseni wa ustekinumab. Ngati mukugwiritsa ntchito jakisoni woyambira kale, uzani dokotala ngati inuyo kapena munthu amene akupatsani jakisoni wamankhwala omwe simukugwirizana ndi latex kapena labala. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: anticoagulants (magazi ochepetsa magazi) monga warfarin (Coumadin, Jantoven) ndi mankhwala omwe amaletsa chitetezo chamthupi monga azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), methotrexate (Otrexup , Rasuvo, Trexall, Xatmep), sirolimus (Rapamune), ndi tacrolimus (Astagraf, Envarsus, Prograf); kapena steroids yamlomo monga dexamethasone (Hemady), methylprednisolone (Medrol), ndi prednisone (Rayos). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi khansa yamtundu uliwonse. Komanso uzani dokotala ngati mwalandira kapena mukulandira Phototherapy kapena kuwombera ziwengo (jakisoni angapo woperekedwa pafupipafupi kuti thupi lisagwidwe ndi zinthu zina).
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukalandira jakisoni wa ustekinumab, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukugwiritsa ntchito jakisoni wa ustekinumab.
• funsani dokotala wanu kuti muwone ngati mukufuna kulandira katemera uliwonse. Ndikofunika kukhala ndi katemera onse oyenera msinkhu wanu musanayambe mankhwala anu ndi jekeseni wa ustekinumab. Musakhale ndi katemera uliwonse mukamalandira chithandizo popanda kulankhula ndi dokotala. Ndikofunikira kwambiri kuti musalandire katemera wa BCG kwa chaka chimodzi musanalandire chithandizo, mukamalandira chithandizo, komanso chaka chimodzi mutalandira chithandizo. Komanso lankhulani ndi dokotala ngati aliyense m'banja lanu akufuna kulandira katemera mukamalandira jekeseni wa ustekinumab.
• muyenera kudziwa kuti jakisoni wa ustekinumab amachepetsa kuthekera kwanu kothana ndi matenda kuchokera ku mabakiteriya, mavairasi, ndi bowa ndikuwonjezera chiopsezo choti mutenga matenda owopsa kapena owopsa. Uzani dokotala wanu ngati nthawi zambiri mumakhala ndi matenda aliwonse kapena ngati muli kapena mukuganiza kuti mutha kukhala ndi matenda aliwonse pano. Izi zimaphatikizapo zotupa zatsopano kapena zosintha pakhungu, matenda ang'onoang'ono (monga mabala otseguka kapena zilonda), matenda omwe amabwera ndikutha (monga zilonda zozizira), ndi matenda osatha omwe samatha. Ngati mukumane ndi izi pazomwe mungachite mukamalandira jekeseni wa ustekinumab kapena mutangomaliza kumene, pitani kuchipatala nthawi yomweyo: kufooka; thukuta; kuzizira; kupweteka kwa minofu; chikhure; chifuwa; kupuma movutikira; malungo; kuonda; kutopa kwambiri; zizindikiro ngati chimfine; khungu lofunda, lofiira, kapena lopweteka; kupweteka kovuta, kovuta, kapena pafupipafupi; kutsegula m'mimba; kupweteka m'mimba; kapena zizindikiro zina za matenda.
• muyenera kudziwa kuti kugwiritsa ntchito jakisoni wa ustekinumab kumawonjezera chiopsezo kuti mudzadwala chifuwa chachikulu (TB; matenda opatsirana m'mapapo), makamaka ngati muli ndi kachilombo ka TB koma mulibe zizindikiro zilizonse za matendawa. Uzani dokotala wanu ngati mwakhalapo ndi TB kapena mudakhalapo ndi TB, ngati mudakhala m'dziko lomwe TB imafala, kapena ngati mudakhalapo ndi munthu amene ali ndi TB. Dokotala wanu adzakuyesani khungu kuti muwone ngati muli ndi kachilombo ka TB kosagwira ntchito. Ngati ndi kotheka, dokotala wanu adzakupatsani mankhwala ochizira matendawa musanayambe kugwiritsa ntchito jakisoni wa ustekinumab. Ngati muli ndi zizindikiro zotsatirazi za chifuwa chachikulu cha TB, kapena ngati mukukhala ndi zina mwazizindikiro mukamalandira chithandizo, pitani kuchipatala nthawi yomweyo: kukhosomola, kupweteka pachifuwa, kutsokomola magazi kapena ntchofu, kufooka kapena kutopa, kuonda, kusowa njala, kuzizira, malungo, kapena thukuta usiku.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Gwiritsani ntchito mlingo womwe mwaphonya mukangokumbukira ndikupitiliza dongosolo lanu lokhazikika. Musagwiritse ntchito mlingo wawiri kuti mupange omwe mwaphonya.

Jekeseni wa Ustekinumab imatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• yothamanga, mphuno, kapena kuyetsemula
• kutopa
• kufiira kapena kukwiya pamalo obayira
• nseru
• kusanza
• kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la MAWONEKEDWE OTHANDIZA, pitani kuchipatala nthawi yomweyo:

• kugwidwa
• chisokonezo
• masomphenya amasintha
• kumva kukomoka
• zidzolo
• kuyabwa
• ming'oma
• kutupa kwa nkhope, zikope, lilime, kapena mmero
• kuvuta kupuma
• zolimba pachifuwa kapena pakhosi

Jakisoni wa Ustekinumab ungapangitse kuti mukhale ndi khansa. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa.

Jekeseni wa Ustekinumab imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamagwiritsa ntchito mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Sungani mabotolo a ustekinumab ndi ma syringe oyikiratu mufiriji, koma musaziimitse.Sungani mabotolo ndi ma syringe oyikapo bwino m'makatoni awo oyambira kuti muwateteze ku kuwala. Tayani mankhwala aliwonse omwe ndi achikale kapena osafunikanso. Lankhulani ndi wamankhwala wanu za momwe mungagwiritsire ntchito mankhwala anu.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti aone momwe thupi lanu likuyankhira jakisoni wa ustekinumab.

Musalole kuti wina aliyense agwiritse ntchito mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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